P Melado Sánchez

Universidad de Las Palmas de Gran Canaria, Las Palmas, Canary Islands, Spain

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Publications (3)2.89 Total impact

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    ABSTRACT: A 73-year-old man was admitted to our hospital after convulsive seizures preceded by encephalopathy lasting one week. He had a history of long-standing chronic obstructive pulmonary disease and analysis showed hypokalemia, respiratory alkalosis and toxic levels of theophylline. We discuss the severity of the convulsions and arrhythmias, the high incidence of hypokalemia in theophylline poisoning, as well as the role of hypokalemia in the pathogenesis of the convulsions and the high level of mortality in this type of intoxication. Other possible mechanisms involved in theophylline encephalopathy are mentioned, along with the controversial use of theophylline for continuous treatment of chronic obstructive pulmonary disease.
    Archivos de Bronconeumología 01/1995; 31(7):368-70. · 1.82 Impact Factor
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    ABSTRACT: A patient with AIDS was admitted to our hospital because of pruritic and disabling erythroderma, it was treated with Lindane without improvement. Skin biopsy of a crusty lesion showed Sarcoptes scabiei hominis, and the diagnosis of Norwegian scabies was made. After a long and intensive treatment with several drugs, cure was achieved. In the following three months we detected 42 people with scabies, all in some relation with the index case. This feature of high contagiousness of Norwegian scabies in a constant, through the scanty literature we have found; and it is due to its diagnostic and therapeutic problems.
    Revista Clínica Española 10/1993; 193(4):155-8. · 1.06 Impact Factor
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    ABSTRACT: Over a 2-year period, 3 patients with deep venous thrombosis associated to advanced pulmonary tuberculosis have been observed. One of them died suddenly, probably due to thromboembolic complications. In the other two cases, a triggering factor of venous thrombosis, probably related to tuberculosis, was detected and their evolution was satisfactory. The high frequency of antiphospholipid antibodies detected in the tuberculosis and the potential relationship between these and deficit of protein S is mentioned. Advanced pulmonary tuberculosis is described as a risk factor for the development of venous thrombosis in patients with negative serology for human immunodeficiency virus type 1 and 2. We recommend not to use deep venous catheters and we stress the potential value of heparin prophylactic therapy in order to prevent venous thrombosis and its complications.
    Anales de medicina interna (Madrid, Spain: 1984) 09/1993; 10(8):398-400.