Peter Roggentin

Publications of Peter Roggentin

• Babies and bearded dragons: sudden increase in reptile-associated Salmonella enterica serovar Tennessee infections, Germany 2008.

  Authors: Bettina Weiss, Wolfgang Rabsch, Rita Prager, Erhard Tietze, Judith Koch, Frank Mutschmann, Peter Roggentin, Christina Frank

  Vector borne and zoonotic diseases (Larchmont, N.Y.). 05/2011; 11(9):1299-301.

  In 2008 a marked increase in Salmonella enterica serovar Tennessee infections in infants occurred in Germany. In March and April 2008, eight cases were notified compared to a median of 0-1 cases inIn 2008 a marked increase in Salmonella enterica serovar Tennessee infections in infants occurred in Germany. In March and April 2008, eight cases were notified compared to a median of 0-1 cases in 2001-2006. We carried out an investigation including a case-control study to identify the source of infection. A patient was a child < 3 years of age with Salmonella Tennessee isolated from stool from September 1, 2007, through December 31, 2008, identified through the national surveillance system. A control was a child with a notified rotavirus infection in the matching district, frequency matched by age group. We conducted telephone interviews on feeding, herbal infusions, and animal contact. Matched odds ratios (mOR) were calculated using exact conditional logistic regression. For Salmonella Tennessee isolates, pulsed-field gel electrophoresis and multiple-locus variable number tandem repeat analysis were performed. Further cloacal swab samples of reptiles kept in case households were investigated. We identified 18 cases < 3 years. Ten children were male; median age was 3 months (1-32 months). In 8 of 16 case households reptiles were kept. Direct contact between child and reptile was denied. Other forms of reptile contact were reported in four of the remaining eight households. Ten case- and 21 control-patients were included in the study. Only keeping of a reptile and "any reptile contact" were associated with Salmonella Tennessee infection (mOR 29.0; 95% CI 3.1 ± ∞ and mOR 119.5; 95% CI 11.7 - ∞). Identical Salmonella Tennessee strains of child and reptile kept in the same household could be shown in 2 cases. Reptiles were the apparent source of Salmonella Tennessee infection in these infants. Indirect contact between infants and reptiles seems to be sufficient to cause infection and should therefore be avoided.

• Supplement 2003-2007 (No. 47) to the White-Kauffmann-Le Minor scheme.

  Authors: Martine Guibourdenche, Peter Roggentin, Matthew Mikoleit, Patricia I Fields, Jochen Bockemühl, Patrick A D Grimont, François-Xavier Weill

  Research in microbiology. 10/2009;

  This supplement reports the characterization of 70 new Salmonella serovars recognized between 2003 and 2007 by the WHO Collaborating Center for Reference and Research on Salmonella: 44 were assignedThis supplement reports the characterization of 70 new Salmonella serovars recognized between 2003 and 2007 by the WHO Collaborating Center for Reference and Research on Salmonella: 44 were assigned to Salmonella enterica subspecies enterica, 11 to subspecies salamae, 5 to subspecies arizonae, 8 to subspecies diarizonae, one to subspecies houtenae and one to Salmonella bongori. One new serovar, Mygdal, displayed a new H factor, H:z(91).

• Shiga toxin-producing Escherichia coli infection in Germany: different risk factors for different age groups.

  Authors: Dirk Werber, Susanne C Behnke, Angelika Fruth, Roswitha Merle, Susanne Menzler, Sabine Glaser, Lothar Kreienbrock, Rita Prager, Helmut Tschäpe, Peter Roggentin, Jochen Bockemühl, Andrea Ammon

  American journal of epidemiology. 02/2007; 165(4):425-34.

  The authors conducted a matched case-control study in Germany to identify risk factors for sporadic illness associated with Shiga toxin-producing Escherichia coli (STEC) infection, regardless ofThe authors conducted a matched case-control study in Germany to identify risk factors for sporadic illness associated with Shiga toxin-producing Escherichia coli (STEC) infection, regardless of serogroup. From April 2001 through March 2003, cases were prospectively enrolled through a laboratory-based sentinel surveillance system located in 14 of the 16 German federal states. One control was identified per case, matched by age and region. Conditional logistic regression was used in the analysis, which was conducted separately for three age groups (<3 years, 3-9 years, and > or =10 years). The median age of the 202 enrolled cases was 2.5 years (range, 3 months-89 years). Hemolytic uremic syndrome developed in five patients. Non-O157 strains accounted for 85% of the isolated STEC. In children under 3 years of age, having touched a ruminant had the highest odds of disease, and raw milk was the only food identified as a risk factor. In contrast, in persons aged 10 years or older, only food items (i.e., lamb meat, raw spreadable sausages) were significantly associated with illness. In this study, risk factors were age-specific. Direct transmission through food played a lesser role in children under 3 years of age, the population at greatest risk of both acquiring STEC infection and developing hemolytic uremic syndrome.

• Salmonella agona outbreak from contaminated aniseed, Germany.

  Authors: Judith Koch, Annette Schrauder, Katharina Alpers, Dirk Werber, Christina Frank, Rita Prager, Wolfgang Rabsch, Susanne Broll, Fabian Feil, Peter Roggentin, Jochen Bockemühl, Helmut Tschäpe, Andrea Ammon, Klaus Stark

  Emerging infectious diseases. 08/2005; 11(7):1124-7.

  A nationwide outbreak of Salmonella Agona caused by aniseed-containing herbal tea occurred from October 2002 through July 2003 among infants in Germany. Consumers should adhere strictly to brewingA nationwide outbreak of Salmonella Agona caused by aniseed-containing herbal tea occurred from October 2002 through July 2003 among infants in Germany. Consumers should adhere strictly to brewing instructions, although in exceptional cases this precaution may not be protective, particularly when preparing tea for vulnerable age groups.

• International outbreak of Salmonella Oranienburg due to German chocolate.

  Authors: Dirk Werber, Johannes Dreesman, Fabian Feil, Ulrich van Treeck, Gerhard Fell, Steen Ethelberg, Anja M Hauri, Peter Roggentin, Rita Prager, Ian S T Fisher, Susanne C Behnke, Edda Bartelt, Ekkehard Weise, Andrea Ellis, Anja Siitonen, Yvonne Andersson, Helmut Tschäpe, Michael H Kramer, Andrea Ammon

  BMC infectious diseases. 03/2005; 5(1):7.

  BACKGROUND: This report describes a large international chocolate-associated Salmonella outbreak originating from Germany. METHODS: We conducted epidemiologic investigations including a case-controlBACKGROUND: This report describes a large international chocolate-associated Salmonella outbreak originating from Germany. METHODS: We conducted epidemiologic investigations including a case-control study, and food safety investigations. Salmonella (S.) Oranienburg isolates were subtyped by the use of pulsed-field gel electrophoresis (PFGE). RESULTS: From 1 October 2001 through 24 March 2002, an estimated excess of 439 S. Oranienburg notifications was registered in Germany. Simultaneously, an increase in S. Oranienburg infections was noted in other European countries in the Enter-net surveillance network. In a multistate matched case-control study in Germany, daily consumption of chocolate (matched odds ratio [MOR]: 4.8; 95% confidence interval [CI]: 1.3-26.5), having shopped at a large chain of discount grocery stores (MOR: 4.2; CI: 1.2-23.0), and consumption of chocolate purchased there (MOR: 5.0; CI: 1.1-47.0) were associated with illness. Subsequently, two brands from the same company, one exclusively produced for that chain, tested positive for S. Oranienburg. In two other European countries and in Canada chocolate from company A was ascertained that also contained S. Oranienburg. Isolates from humans and from chocolates had indistinguishable PFGE profiles. No source or point of contamination was identified. Epidemiological identification of chocolate as a vehicle of infections required two months, and was facilitated by proxy measures. CONCLUSIONS: Despite the use of improved production technologies, the chocolate industry continues to carry a small risk of manufacturing Salmonella-containing products. Particularly in diffuse outbreak-settings, clear associations with surrogates of exposure should suffice to trigger public health action. Networks such as Enter-net have become invaluable for facilitating rapid and appropriate management of international outbreaks.

• A nationwide outbreak of Salmonella Bovismorbificans PT24, Germany, December 2004-March 2005.

  Authors: Andreas Gilsdorf, Andreas Jansen, Katharina Alpers, Helga Dieckmann, Ulrich van Treeck, Anja M Hauri, Gerhard Fell, Martina Littmann, Peter Rautenberg, Rita Prager, Wolfgang Rabsch, Peter Roggentin, Andreas Schroeter, Angelika Miko, Edda Bartelt, Juliane Braunig, Andrea Ammon

  Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin. 02/2005; 10(3):E050324.1.

• Sequence-based typing of flaB is a more stable screening tool than typing of flaA for monitoring of Campylobacter populations.

  Authors: Alexander Mellmann, Jan Mosters, Edda Bartelt, Peter Roggentin, Andrea Ammon, Alexander W Friedrich, Helge Karch, Dag Harmsen

  Journal of clinical microbiology. 11/2004; 42(10):4840-2.

  Different typing schemes for Campylobacter spp. were evaluated with 70 outbreak and sporadic isolates. The discriminatory indexes were 0.944 (by pulsed-field gel electrophoresis), 0.920 (byDifferent typing schemes for Campylobacter spp. were evaluated with 70 outbreak and sporadic isolates. The discriminatory indexes were 0.944 (by pulsed-field gel electrophoresis), 0.920 (by genotyping of the flagellin A gene), 0.902 (by genotyping of flaB), and 0.886 (by multilocus sequence typing). Cross-classification gave 94.77 or 95.82% (PFGE-flaA or PFGE-flaB) concordance. flaA was overdiscriminatory in three cases, most probably due to intragenomic recombination.

• Molecular epidemiology of Salmonella enterica serovar Agona: characterization of a diffuse outbreak caused by aniseed-fennel-caraway infusion

  Authors: Wolfgang Rabsch, Rita Prager, Judith Koch, Klaus Stark, Peter Roggentin, Jochen Bockemühl, G. Beckmann, R. Stark, W. Siegl, Andrea Ammon, Helmut Tschäpe

  During 2002-2003 increased numbers of notified salmonellosis due to S. enterica serovar Agona were observed in Germany. In order to understand the recent spread of this serovar and to trace the routeDuring 2002-2003 increased numbers of notified salmonellosis due to S. enterica serovar Agona were observed in Germany. In order to understand the recent spread of this serovar and to trace the route of infection to its source, a new phage-typing scheme and pulsed field gel electrophoresis (PFGE) were used to analyse these isolates. By using 14 bacteriophages, 52 phage types were distinguished among the S. Agona strains. PFGE also differentiated 52 different patterns. A combination of both methods generated 94 clonal types among 165 S. Agona strains originating from Germany and other countries including the United States, United Arab Emirates, Turkey, India, Austria and Finland, indicating a great biological diversity within this serovar. However, 36 recent S. Agona isolates from infantile gastroenteritis in Germany, from an untreated batch of aniseed imported from Turkey and from fennel-aniseed-caraway infusion (packed in tea bags) revealed clonal identity indicating their epidemiological relatedness as a new source of infection. It is suggested that strains of S. Agona will continue to be of public health concern, and that phage typing together with PFGE typing should be applied as reliable and rapid tools for epidemiological subtyping and future monitoring.