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ABSTRACT: Digital pelvic radiographs are used to identify the locations of implanted iodine-125 seeds and their numbers after insertion. However, it is difficult and laborious to visually identify and count all implanted seeds on the pelvic radiographs within a short time. Therefore, our purpose in this research was to develop an automated method for estimation of the number of implanted seeds based on two-view analysis of pelvic radiographs. First, the images of the seed candidates on the pelvic image were enhanced using a difference of Gaussian filter, and were identified by binarizing the enhanced image with a threshold value determined by multiple-gray level thresholding. Second, a simple rule-base method using ten image features was applied for false positive removal. Third, the candidates for the likely number of a multiply overlapping seed region, which may include one or more seeds, were estimated by a seed area histogram analysis and calculation of the probability of the likely number of overlapping seeds. As a result, the proposed method detected 99.9% of implanted seeds with 0.71 false positives per image on average in a test for training cases, and 99.2% with 0.32 false positives in a validation test. Moreover, the number of implanted seeds was estimated correctly at an overall recognition rate of 100% in the validation test using the proposed method. Therefore, the verification time for the number of implanted seeds could be reduced by the provision of several candidates for the likely number of seeds.
Journal of Radiation Research 07/2012; 53(5):742-52. · 1.68 Impact Factor
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Hidemichi Kawata
Nippon Hoshasen Gijutsu Gakkai zasshi 07/2010; 66(7):791-801.
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ABSTRACT: We evaluated an appropriate region of interest (ROI) size for the measurement of full width at half maximum (FWHM) in the bead method (0.1 mm and 0.5 mm diameter; lead) and the microdisk method (0.05 mm thickness and 1.0 mm diameter; tungsten) using multislice computed tomography (CT). The FWHM of preset slice thicknesses 0.625 mm, 1.25 mm, 5.0 mm and 7.5 mm were measured by varying helical pitch, location of measurement [center and off-center of scan field of view (SFOV)] and ROI size, and they were compared with the tolerance stated in the Japanese Industrial Standards (JIS). It was conlcuded that the appropriate ROI size was influenced by preset slice thickness in this study. At the center of SFOV, measurements of FWHM were enabled within the tolerance of the JIS with small variations in all preset slice thicknesses if the ROI sizes were set between 0.4 times and equal to the size of the bead or microdisk indicating the maximum CT value in the series of CT images. At the off-center of SFOV, the tendency of increasing FWHM was confirmed, but it was shown that variations of the off-center in thicker slice thickness were larger regardless of helical pitch when the orbital synchronized helical scan technique was not used.
Nippon Hoshasen Gijutsu Gakkai zasshi 03/2010; 66(3):217-24.
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Hidemichi Kawata
Nippon Hoshasen Gijutsu Gakkai zasshi 07/2009; 65(6):727.
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ABSTRACT: Determination of the region of interest (ROI) for dynamic renal function has been highly discordant among operators because of the dependence on factors such as the rate of injection of radioactive medicines, constitution, and renal function. To simplify this problem, we developed a computer algorithm that provides automatic analysis for both localization of the kidney and automatic determination of ROIs using computed tomographic (CT) images. The bilateral kidneys were extracted from enhanced CT images, and the CT pixel size was adjusted to dynamic renal function images. The template-matching technique was used for these images, and the kidney renal location was analyzed on additional functional images constructed by dynamic renal function images. As a result, we were able to obtain time-activity curves of both renal function and quantified glomerular filtration rate (GFR). In conclusion, the computer algorithm we developed was considered to provide reliable results, apart from the variability among operators, because of its good reproducibility.
Nippon Hoshasen Gijutsu Gakkai zasshi 01/2008; 63(12):1377-81.
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ABSTRACT: Recent progress in radiation therapy has been greatly enhanced in many facilities by the development of new machines for treatment, improved computer technology for radiotherapy treatment planning systems (RTPs), increased accuracy of radiation therapy such as stereotactic irradiation, and intensity-modulated radiation therapy (IMRT). Quality control (QC) of the isocenter, which has consisted of gantry rotation and limiting the radiation field, is important for greater accuracy of these radiation therapy technologies. Star-shot analyses using computed radiography (CR) for evaluation of the isocenter were employed in this study. Devices to support CR were created, and a method of automatically analyzing images obtained by the star-shot technique, which calculated the error (distance) from the isocenter and the incident beam angle, were developed. In terms of the accuracy of our method, the average maximum error was 0.33 mm (less than 2 pixels: 0.35 mm), the average absolute error and incident beam angle errors were 0.3 mm and 0.4 degrees at maximum and at one standard deviation (SD), respectively. In this study, the processing times were 16 sec at minimum, 152 sec at maximum, 18 sec at most frequencies, and 23.6 sec on average. In conclusion, it was considered that our newly developed method for analyzing star-shot images using CR enabled immediate, quantitative evaluation of the isocenter.
Nippon Hoshasen Gijutsu Gakkai zasshi 01/2007; 62(12):1657-65.
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Hidemichi Kawata
Nippon Hoshasen Gijutsu Gakkai zasshi 09/2005; 61(8):1106-10.
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Seiji Kawamura,
Shigehiro Fukushima,
Yukiyasu Yoshinaga, Hidemichi Kawata,
Hisao Miura,
Teruo Miyagawa,
Yoshifumi Fukudome,
Noriyoshi Umezaki,
Masatoshi Ishibashi,
Seiichiro Morita,
Naofumi Hayabuchi
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ABSTRACT: The temporal image subtraction technique was applied to bone scintigraphy, using Photoshop (commercially available image processing software) and Morpher (public domain warping software). For the temporal subtraction images, 81 subtraction images (19 cases) were prepared by a method used to subtract the previous images from the current ones. Registration of the current and previous images was performed by manual operation using Photoshop, and warping was done using the warping function of Morpher. In addition, difference images prepared after correcting the distributions of radioactive isotopes of the current and previous images using the count of the pelvic region were also examined. Compared with manual operation, alignment of images by warping improved registration and reduced the generation of pseudo-images of subtraction images. The rate of identification of abnormal accumulation-enhanced regions and subjective evaluation by doctors was improved for warping more than for manual operation. Furthermore, abnormal hot regions, which are difficult to find in film images, could be found in three subtraction images. In addition, it was confirmed that abnormal hot regions become more visible in many cases by preparing subtraction images after correcting the count between images using the count of the pelvic region. Thus, it is suggested that the temporal image subtraction technique in bone scintigraphy enables more accurate observation of enhancement of or changes in abnormal hot regions, which will support diagnostic reading. It is considered that enhancement of or changes in abnormal hot regions will be more accurately understood through further detailed discussion in the future.
Nippon Hoshasen Gijutsu Gakkai zasshi 08/2005; 61(7):997-1005.
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ABSTRACT: Magnetization transfer contrast (MTC) was evaluated by changing the off-set frequency and pulse intensity of MTC with the spoiled gradient echo (SPGR) sequence (T2*-weighted image) using an experimental phantom that included olive oil, protein, fiber, collagen, and pure water. The intensity of pure water reached a constant level just above the off-set frequency (1200 Hz) regardless of MT pulse power. The contrast-to-noise ratio (CNR) in each of the phantom materials was maximal at the MT pulse power of 2500 degrees (equivalent flip angle). The CNR and image noise obtained by body coil were inferior to those obtained with an extremity coil. In clinical application, the MTC effect on chondrosarcoma was higher (MT ratio, ROI-1:0.448, ROI-2:0.382) than those of other cases in this study. Since the image contrast was improved between the malignant fibrous histiocytoma (MFH, MT ratio, ROI-1:0.282, ROI-2:0.289) and peripheral tissues, extraskeletal extension could be observed more easily than without MTC imaging. In conclusion, the effects of MTC might be in providing useful information, in presuming composed tissues, differential diagnoses, and extent to the surrounding structures because of changing the image contrast to surrounding tissues corresponding to the rate of included bound water.
Nippon Hoshasen Gijutsu Gakkai zasshi 11/2004; 60(10):1437-43.
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Hidemichi Kawata
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ABSTRACT: Beam quality for digital chest radiography in digital radiography systems (DR systems) with RbBr:Tl(+) photostimulable storage phosphors was investigated. Measurements of overall Wiener spectrum (overall WS) and observer performance experiments by means of Scheffé's method of paired comparisons were performed under the same exposure (5.16x10(-7)C/kg) at the X-ray detector of DR systems (sampling distance: 175 micro m, 2,048x2,048 pixels, 12 bits, look-up table: THX2) with a phantom lung and metacryl plates. Overall WS values were indicated to be inferior at higher tube voltages. All of the overall WS values were greater than those of screen film systems (HGM/UR1:S/F) at radiographic density 0.50, which was considered the density of the mediastinum and the area below the diaphragm (low density area), and at radiographic densities 1.00 and 1.50, considered as lung, WS values of S/F were located between the overall WS values of 80 kV and 100 kV, and 120 kV and 140 kV, respectively. Evaluation of visibility including mediastinum, lung, and total were indicated to be superior at the lower tube voltages. In evaluation of the mediastinum, the base image, which was obtained by 100 kV tube voltage (effective energy: 46.0 kV) in this study, was not significant from 90 kV to 110 kV tube voltages (range, +/-10 kV), and in-lung and total evaluations were not significant from 90 kV to 120 kV (range, -10 kV to +20 kV), and from 80 kV to 120 kV (range, +/-20 kV) tube voltages by 99% confidence interval. In conclusion, optimal beam quality for digital chest radiography with RbBr:Tl(+) photostimulable storage phosphors was considered to be less than 110 kV tube voltage (effective energy, 47.9 keV) in 0.1 mm copper and 3.8 mm aluminum total filtration. In this case, the granularity in low-density areas were inferior to those of S/F systems but nearly equal to the middle and high-density areas of chest images, and exposure dose was 14.3% lower than that of the base image obtained by 100 kV (effective energy, 46.0 keV) tube voltage in this study.
Nippon Hoshasen Gijutsu Gakkai zasshi 10/2003; 59(9):1174-82.
