Ramin Ghahremanzadeh

Publications (18)38.99 Total impact

• Article: Ultrasound-assisted synthesis of 2,2'-(2-oxoindoline-3,3-diyl)bis(1H-indene-1,3(2H)-dione) derivatives.

  Ramin Ghahremanzadeh, Fatemeh Fereshtehnejad, Peiman Mirzaei, Ayoob Bazgir
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  ABSTRACT: A simple and efficient procedure for the synthesis of 2,2'-(2-oxoindoline-3,3-diyl)bis(1H-indene-1,3(2H)-dione) derivatives, 2,2'-(2-oxo-1,2-dihydroacenaphthylene-1,1-diyl)bis(1H-indene-1,3(2H)-dione) and 2,2'-(1,3-dioxo-2,3-dihydro-1H-indene-2,2-diyl)bis(1H-indene-1,3(2H)-dione) by the reaction of 1,3-indandione and isatins or acenaphthylene-1,2-dione or ninhydrine in ethanol under ultrasonic irradiation in the presence of p-TSA is reported. The advantages of this method are the use of an inexpensive and readily available catalyst, easy work-up, good yields, and the use of ethanol as a solvent that is considered to be relatively environmentally benign.
  Ultrasonics Sonochemistry 01/2011; 18(1):415-8. · 3.57 Impact Factor
• Article: WITHDRAWN: Sonochemical three-component synthesis of pyrazolotriazoles.

  Ramin Ghahremanzadeh, Fatemeh Fereshtehnejad, Ghaffar Hosseini, Ayoob Bazgir
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  ABSTRACT: This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
  Ultrasonics Sonochemistry 12/2010; · 3.57 Impact Factor
• Article: One‐pot synthesis of spiro[diindeno[1,2‐b:2′,1′‐e]pyridine‐11,3′‐indoline]‐triones

  Ramin Ghahremanzadeh, Fatemeh Fereshtehnejad, Ayoob Bazgir
  Journal of Heterocyclic Chemistry 07/2010; 47(5):1031 - 1034. · 1.22 Impact Factor
• Article: Three-component synthesis of 2-oxoindolin-3-ylphosphonates.

  Ghazaleh Imani Shakibaei, Afsaneh Feiz, Ramin Ghahremanzadeh, Ayoob Bazgir
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  ABSTRACT: A one-pot, three-component and catalyst-free method for the efficient and simple synthesis of dialkyl 3-(dicyanomethyl)-2-oxoindolin-3-ylphosphonates at 50 degrees C under solvent-free conditions is reported. The features of this procedure are mild reaction conditions, high yields of products, and operational simplicity.
  Chemical & pharmaceutical bulletin 07/2010; 58(7):896-900. · 1.70 Impact Factor
• Article: One‐pot and three‐component synthesis of spiro[chromeno[2,3‐d] pyrimidine‐5,3′‐indoline]‐diones and spiro[chromeno[2,3‐c] pyrazole‐4,3′‐indoline]‐diones

  Ramin Ghahremanzadeh, Fatemeh Fereshtehnejad, Zahra Yasaei, Tayebeh Amanpour, Ayoob Bazgir
  Journal of Heterocyclic Chemistry 06/2010; 47(4):967 - 972. · 1.22 Impact Factor
• Article: Chromeno[2,3-d]pyrimidine-triones synthesis by a three-component coupling reaction.

  Ramin Ghahremanzadeh, Fatemeh Fereshtehnejad, Ayoob Bazgir
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  ABSTRACT: A simple and one-pot synthesis of new chromeno[2,3-d]pyrimidine-triones by a three-component condensation reaction of barbituric acids, aldehydes and cyclohexane-1,3-diones in refluxing ethanol in the presence of p-toluenesulfonic acid (p-TSA) for 3-10 h is reported. Two cyclohexane-1,3-diones, four barbituric acids and six substituted aldehydes were chosen for the library validation. Prominent among the advantages of this new method are operational simplicity, good yields and easy work-up procedures employed.
  Chemical & pharmaceutical bulletin 04/2010; 58(4):516-20. · 1.70 Impact Factor
• Article: Simple and catalyst-free synthesis of oxoindolin-3-yl phosphonates.

  Ghazaleh Imani Shakibaei, Saadi Samadi, Ramin Ghahremanzadeh, Ayoob Bazgir
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  ABSTRACT: An efficient, simple, and catalyst-free synthesis of dialkyl or diaryl 3-(dicyanomethyl)-2-oxoindolin-3-ylphosphonates by the reaction of dialkyl or diaryl phosphites and oxoindolin-3-ylidenemalononitriles under solvent-free conditions is reported. The reaction of imino isatins with dialkyl or diaryl phosphites results in the formation of dialkyl or diaryl 2-oxo-3-(arylamino)indolin-3-ylphosphonates.
  Journal of Combinatorial Chemistry 03/2010; 12(2):295-7. · 3.41 Impact Factor
• Article: One‐pot, three‐component synthesis of spironaphthopyrano[2,3‐d]pyrimidine‐5,3′‐indolines in water

  Ramin Ghahremanzadeh, Tayebeh Amanpour, Maryam Sayyafi, Ayoob Bazgir
  Journal of Heterocyclic Chemistry 03/2010; 47(2):421 - 424. · 1.22 Impact Factor
• Article: Clean synthesis of spiro[indole‐3,8′‐phenaleno[1,2‐b]pyran]‐9′‐carbonitriles and spiro[indole‐3,4′‐pyrano[4,3‐b]pyran]‐3′‐carbonitriles by one‐pot, three‐component reactions

  Ramin Ghahremanzadeh, Tayebeh Amanpour, Ayoob Bazgir
  Journal of Heterocyclic Chemistry 12/2009; 47(1):46 - 49. · 1.22 Impact Factor
• Article: An efficient, three‐component synthesis of spiro[benzo[g]chromene‐4,3′‐indoline]‐3‐carbonitrile and spiro[indoline‐3,5′‐pyrano[2,3‐d]pyrimidine]‐6′‐carbonitrile derivatives

  Ramin Ghahremanzadeh, Tayebeh Amanpour, Ayoob Bazgir
  Journal of Heterocyclic Chemistry 11/2009; 46(6):1266 - 1270. · 1.22 Impact Factor
• Article: One-pot, pseudo four-component synthesis of a spiro[diindeno[1,2-b:2',1'-e]pyridine-11,3'-indoline]-trione library.

  Ramin Ghahremanzadeh, Ghazaleh Imani Shakibaei, Somayeh Ahadi, Ayoob Bazgir
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  ABSTRACT: A one-pot, pseudo four-component method for the efficient and simple synthesis of spiro[diindeno[1,2-b:2',1'-e]pyridine-11,3'-indoline]-2',10,12-trione derivatives in refluxing acetonitrile is reported. The features of this procedure are mild reaction conditions, high yields of products, and operational simplicity.
  Journal of Combinatorial Chemistry 10/2009; 12(1):191-4. · 3.41 Impact Factor
• Article: Ultrasound-assisted one-pot, three-component synthesis of spiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-2,6'(1'H)-diones in water.

  Ayoob Bazgir, Somayeh Ahadi, Ramin Ghahremanzadeh, Hamid Reza Khavasi, Peiman Mirzaei
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  ABSTRACT: A simple, facile, efficient and three-component procedure for the synthesis of spiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-2,6'(1'H)-diones by the reaction of 4-hydroxycumarin, isatins and 1H-pyrazol-5-amines in water under ultrasonic irradiation is reported. The advantages of this method are the use of an inexpensive and readily available catalyst, easy work-up, good yields, and the use of water as a solvent that is considered to be relatively environmentally benign.
  Ultrasonics Sonochemistry 09/2009; 17(2):447-52. · 3.57 Impact Factor
• Article: Ultrasound-assisted one-pot, three-component synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones.

  Mohammad Reza Nabid, Seyed Jamal Tabatabaei Rezaei, Ramin Ghahremanzadeh, Ayoob Bazgir
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  ABSTRACT: Triethylamine was found to be an efficient catalyst for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by one-pot reaction of phthalhydrazide, aromatic aldehydes, and malononitrile or ethyl cyanoacetate in ethanol under ultrasonic irradiation. The advantages of this method are the use of an inexpensive and readily available catalyst, easy workup, improved yields, and the use of ethanol as a solvent that is considered to be relatively environmentally benign.
  Ultrasonics Sonochemistry 07/2009; 17(1):159-61. · 3.57 Impact Factor
• Article: Efficient synthesis of spiro[chromeno[2,3-d]pyrimidine-5,3'-indoline]-tetraones by a one-pot and three-component reaction.

  Khosrow Jadidi, Ramin Ghahremanzadeh, Ayoob Bazgir
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  ABSTRACT: An efficient one-pot synthesis of novel 8,9-dihydrospiro[chromeno[2,3-d]pyrimidine-5,3'-indoline]-2,2',4,6(1H,3H,7H)-tetraone derivatives by a three-component condensation reaction of barbituric acids, isatins and cyclohexane-1,3-diones in refluxing water in the presence of p-TSA for 10 h is reported. Two cyclohexane-1,3-diones, three barbituric acids, and eight substituted isatins were chosen for the library validation. Reaction of 5,5-dimethyl-cyclohexane-1,3-dione and acenaphthylene-1,2-dione with barbituric acids resulted in the formation of spiro[acenaphthylene-1,5'-chromeno[2,3-d]pyrimidine] derivatives.
  Journal of Combinatorial Chemistry 03/2009; 11(3):341-4. · 3.41 Impact Factor
• Article: Clean synthesis and antibacterial activities of spiro[pyrimido[4,5-b]quinoline-5,5'-pyrrolo[2,3-d]pyrimidine]-pentaones.

  Ramin Ghahremanzadeh, Seyyedeh Cobra Azimi, Nader Gholami, Ayoob Bazgir
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  ABSTRACT: A simple, clean and efficient method for the synthesis of spiro[pyrimido[4,5-b]quinoline-5,5'-pyrrolo[2,3-d]pyrimidine]-pentaone derivatives by condensation reaction of 6-amino-uracils and isatins in aqueous media is reported. These products were evaluated in vitro for their antibacterial activities.
  CHEMICAL & PHARMACEUTICAL BULLETIN 12/2008; 56(11):1617-20. · 1.59 Impact Factor
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  Article: Reaction of phthalhydrazide and acetylenedicarboxylates in the presence of N-heterocycles: an efficient synthesis of phthalazine derivatives

  Ramin Ghahremanzadeh, Somayyeh Ahadi, Maryam Sayyafi, Ayoob Bazgir
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  ABSTRACT: a b s t r a c t Some new phthalazine derivatives were prepared by reaction of phthalhydrazide and dialkyl acetylenedi-carboxylates in the presence of N-heterocycles.
  04/2008;
• Article: Eco-friendly synthesis of 1,4-benzodiazepine-2,5-diones in the ionic liquid [bmim]Br

  Khosrow Jadidi, Ramin Ghahremanzadeh, Davoud Asgari, Parisa Eslami, Hamid Arvin-Nezhad
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  ABSTRACT: The green reaction of isatoic anhydrides with �-amino acids in presence of the ionic liquid 1-butyl-3-methylimidazolium bromide afforded 1,4- benzodiazepine-2,5-diones in excellent yields in absence of a catalyst. The reaction workup is simple and the ionic liquid was easily recovered from the reaction and reused. The methodology was quite general and a range of cyclic and acyclic �-amino acids were examined to produce 1,4-benzodiazepine-2,5-diones.
  Monatsh Chem. 01/2008; 139:1229.
• Article: Novel one-pot, three-component synthesis of spiro[indoline-pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine]trione library.

  Ramin Ghahremanzadeh, Maryam Sayyafi, Somayeh Ahadi, Ayoob Bazgir
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  ABSTRACT: A one-pot method for the efficient and simple synthesis of the novel spiro[indoline-pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine]trione derivatives by a three-component condensation reaction of barbituric acids, 1H-pyrazol-5-amines and isatins in aqueous media is reported.
  Journal of Combinatorial Chemistry 11(3):393-6. · 3.41 Impact Factor