Lars Söderström

Publications (3)20.17 Total impact

• Article: IgE to Gly m 5 and Gly m 6 is associated with severe allergic reactions to soybean in Japanese children.

  Komei Ito, Sigrid Sjölander, Sakura Sato, Robert Movérare, Akira Tanaka, Lars Söderström, Magnus Borres, Maryam Poorafshar, Motohiro Ebisawa
  The Journal of allergy and clinical immunology 05/2011; 128(3):673-5. · 9.17 Impact Factor
• Source

  Available from: jsaweb.jp

  Article: Usefulness of wheat and soybean specific IgE antibody titers for the diagnosis of food allergy.

  Takatsugu Komata, Lars Söderström, Magnus P Borres, Hiroshi Tachimoto, Motohiro Ebisawa
  [show abstract] [hide abstract]
  ABSTRACT: Since the first suggestion of threshold values for food specific IgE antibody levels in relation to clinical reactivity, several authors have proposed different threshold values for different allergens. We investigated the relationship between wheat/soybean specific IgE antibody levels and the outcome of wheat/soybean allergy diagnosis in children of different ages. A retrospective study was conducted in 536 children admitted consecutively to our clinic with the suspicion of wheat and/or soybean allergy. The children underwent an oral food challenge and blood samples for specific IgE measurement were obtained. The children who reacted to the oral food challenge had higher specific IgE titers to the specific allergen compared to the non-reacting group. The risk for reaction increased 2.33-fold (95% CI 1.90-2.87) for wheat and 2.08-fold (95% CI 1.65-2.61) for soybean, with increasing levels of specific IgE. A significant difference between the ages of subjects pertained only to wheat. We found a relationship between the probability of failed challenge and the concentration of IgE antibodies to both wheat and soybean. Age influences the relationship of allergen specific IgE levels to wheat and oral food challenge outcome. Younger children are more likely to react to low levels of specific IgE antibody concentration to wheat than older children.
  Allergology International 09/2009; 58(4):599-603.
• Article: The predictive relationship of food-specific serum IgE concentrations to challenge outcomes for egg and milk varies by patient age.

  Takatsugu Komata, Lars Söderström, Magnus P Borres, Hiroshi Tachimoto, Motohiro Ebisawa
  Journal of Allergy and Clinical Immunology 06/2007; 119(5):1272-4. · 11.00 Impact Factor