Giuseppe Catanuto

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milano, Lombardy, Italy

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Publications (15)26.41 Total impact

  • Article: Outcome of different timings of radiotherapy in implant-based breast reconstructions.
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    ABSTRACT: The therapeutic role of postmastectomy radiation therapy has been demonstrated both in locally advanced breast cancer and in other high-risk conditions. Implant-based breast reconstruction for irradiated patients can generate higher complication rates. In this study, the authors observed the effects of radiation on temporary expanders and permanent implants. The estimate of the totally failed reconstruction rate was the principal endpoint of this study. Capsular contracture rates and patients' and surgeons' subjective evaluations were the secondary endpoints. Two hundred fifty-seven patients were consecutively involved in this study. The population was stratified into two groups: group 1, postmastectomy radiation therapy on permanent implants (n = 109 patients); and group 2, postmastectomy radiation therapy on tissue expanders (n = 50 patients). A nonirradiated control group made up of 98 patients was selected randomly. All patients underwent a two-stage immediate breast reconstruction with subpectoral temporary expanders and permanent implants. The totally failed reconstruction rate was significantly higher in group 2, with 40 percent of unsuccessful reconstructions compared with 6.4 percent in group 1 and 2.3 percent in the control group (p < 0.0001). The capsular contracture rate was significantly higher for groups 1 and 2 compared with the control group. The shape and symmetry assessment and the patients' opinions demonstrated a higher incidence of good results in group 1 in comparison with group 2. The best scores were always obtained by the control group. This study demonstrated that radiotherapy during tissue expansion may compromise the outcome of implant-based breast reconstruction. Therapeutic, II.
    Plastic and reconstructive surgery 08/2011; 128(2):353-9. · 2.74 Impact Factor
  • Article: Skin/nipple sparing mastectomies and implant-based breast reconstruction in patients with large and ptotic breast: oncological and reconstructive results.
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    ABSTRACT: In this study we performed 77 procedures on 65 patients fulfilling the oncological criteria for skin-sparing mastectomy and presenting with large or medium size breasts. All the operations were performed as a single-stage procedure with an anatomical prosthesis allocated into a compound pouch, made up of the pectoralis major, serratus anterior fascia, and a lower dermal adipose flap. The medium size of the anatomical implants employed was 444.3 cc. The implant removal rate was 14.2%. At a median follow-up of 36 months we reported a 0.5% local recurrence rate per year. The overall specific survival rate was 98.2%. This study confirms the safety and effectiveness of this technical variation of skin and nipple-sparing mastectomies. All breast, irrespective of mammary shape and size, can be reconstructed with medium size implants and, if required, contralateral adjustments. The overall complication rate is in keeping with previous studies.
    Breast (Edinburgh, Scotland) 03/2011; 21(3):267-71. · 2.09 Impact Factor
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    Conference Proceeding: Human Breast Shape Analysis using PCA.
    BIOSIGNALS 2010 - Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing, Valencia, Spain, January 20-23, 2010; 01/2010
  • Article: Re: Surface area measurement of the female breast: Phase I. Validation of a novel optical technique.
    Plastic and reconstructive surgery 12/2009; 124(6):2194; author reply 2194-5. · 2.74 Impact Factor
  • Article: Motion compensation in hand-held laser scanning for surface modeling in plastic and reconstructive surgery.
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    ABSTRACT: The purpose of this work is to develop a new integrated methodology for breast morphology assessment in plastic and reconstructive surgery. Such a methodology comprises hand-held laser scanning with active compensation of breathing motion and involuntary movements, in order to obtain a thorough and artifacts-free representation of patient breast shape. This was obtained by tracking surface motion with a configuration of passive markers fitted on the patient's thoraco-abdominal region. The proposed method, based on a mapping procedure, has been compared with respiratory gating, that is commonly used in radiotherapy and biomedical imaging applications. The results show that the implemented procedure is adequately able to compensate for motion, resulting in quantitative surface description to be used for clinical evaluation.
    Annals of biomedical engineering 10/2009; 37(9):1877-85. · 2.41 Impact Factor
  • Article: Conservative mastectomies.
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    ABSTRACT: Nowadays, oncological breast surgery has to be performed to maximize cosmetic results, and even mastectomies, when unavoidable, should conform to acceptable aesthetics. We investigated surgical approaches to skin-sparing mastectomies. Scar positioning and volume replacement were evaluated. We also discuss nipple-sparing mastectomy (NSM), probably the most outstanding item in the current debate on breast shape preservation. We give suggestions for safe admission criteria and effective treatment.
    Aesthetic Plastic Surgery 08/2009; 33(5):681-6. · 1.41 Impact Factor
  • Article: Three-dimensional digital evaluation of breast symmetry after breast conservation therapy.
    Giuseppe Catanuto, Andrea Spano, A Pennati, M Nava
    Journal of the American College of Surgeons 02/2009; 208(1):166; author reply 166-7. · 4.55 Impact Factor
  • Article: Extra-projected implants as an alternative surgical model for breast reconstruction. Implantation strategy and early results.
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    ABSTRACT: The present study reports on patients who underwent breast reconstructions with extra-projection implants. Two-hundred and thirty-four women were treated for 238 breast reconstructions irrespectively of breast shape and size. In this series we aimed to reconstruct for all women a bilateral cosmetic medium-size breast (between 400 and 500 cc), highly projected, with a little to moderate ptosis rather then a ptotic one exactly matching the contra-lateral. This is demonstrated by volume of implants that ranged from 397 cc for ladies with small breast who received an augmentation, to 533 cc for those who side required a reduction surgery. Eighty-six percent of patients received contra-lateral procedures. Complication rate was 8.4% and 66% of reconstructions were rated as good in the patients' opinion. Extra-projection implants, coupled with contra-lateral breast surgery, provide a good aesthetic outcome and avoid myocutaneous flaps only on the basis of breast size and shape.
    The Breast 06/2008; 17(4):361-6. · 2.49 Impact Factor
  • Article: Silicone barrier sheath as an "oncologic vallum" in two-stage reconstruction with expanders for large, recurrent, soft-tissue cancer.
    Egidio Riggio, Giuseppe Catanuto, Maurizio B Nava
    Plastic and reconstructive surgery 02/2007; 119(1):445-6. · 2.74 Impact Factor
  • Article: Skin-reducing mastectomy.
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    ABSTRACT: The authors propose a combined flap technique to reconstruct large and medium-sized ptotic breasts in a single-stage operation by use of anatomical permanent implants. The authors enrolled 28 patients fulfilling criteria for skin-sparing mastectomy and presenting with ptotic breasts whose areola-to-inframammary fold distance was more than 8 cm. All reconstructions were performed as a single-stage procedure. After preoperative planning, a large area in the lower half of the breast was deepithelialized according to the conventional Wise pattern. Mastectomy was then carried out. To perform reconstructions, the inferomedial fibers of the pectoralis major muscle were dissected and sutured to the superior border of the inferior dermal flap. An anatomical implant was then inserted into the pouch, which was closed laterally with the previously harvested serratus anterior fascia. Skin flaps were finally closed down to the inframammary fold. The authors performed 30 procedures on 28 patients. The medium size anatomical implants was 433 cc. Twelve women achieved symmetrization in a single stage ending in a symmetric inverted-T scar. The overall complication rate was 20 percent, with four cases (13 percent) complicated by severe, extensive necrosis of the skin flaps requiring implant removal. Breast cancer treatment must nowadays optimize cosmetic results. This can be accomplished in selected cases by means of a single-stage operation that the authors call "skin-reducing mastectomy." The final scars imitate those of cosmetic surgery. Careful patient selection and improvement in the learning curve may reduce the complication rate.
    Plastic and reconstructive surgery 10/2006; 118(3):603-10; discussion 611-3. · 2.74 Impact Factor
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    Article: Objective outcome evaluation of breast surgery.
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    ABSTRACT: A new method is proposed to unambiguously define a geometric partitioning of 3D models of female thorax. A breast partitioning scheme is derived from simple geometric primitives and well-defined anatomical points. Relevant measurements can be extrapolated from breast partition. Our method has been tested on a number of breast 3D models acquired by means of a commercial scanner on real clinical cases.
    Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 02/2006; 9(Pt 1):776-83.
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    Conference Proceeding: Unambiguous Analysis of Woman Breast Shape for Plastic Surgery Outcome Evaluation.
    Fourth Eurographics Italian Chapter Conference 2006, University of Catania, Italy, 22-24 February 2006; 01/2006
  • Article: Re: Wise pattern mastectomy with immediate breast reconstruction.
    The Breast 09/2005; 14(4):333; author reply 334. · 2.49 Impact Factor
  • Article: Biliary squamous cell carcinoma.
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    ABSTRACT: Squamous cell carcinoma of the liver, bile ducts and gallbladder is extremely rare. We report a case of squamous cell carcinoma of the common bile duct manifesting atypically without jaundice, despite its large size and proximal bile duct dilation. A review of the literature concerning all other squamous carcinoma of the biliary tract is presented including 3 other bile duct cancers, 17 intrahepatic and 30 gallbladder cancers. Compared to the more common adenocarcinoma these rare biliary cancers seem to present particular clinical features and prognostic differences which may be important for planning treatment.
    Chirurgia italiana 56(2):289-95.
  • Article: New technologies for the assessment of breast surgical outcomes.
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    ABSTRACT: Although interest in objective and quantitative breast surgical outcome assessment is rapidly increasing, published reports have yet to make a real impact on everyday clinical practice. The authors offer a preliminary report on an innovative methodology customized for breast shape evaluation that, in our opinion, could overcome most of the technical and conceptual limitations of previous studies. Three-dimensional/four-dimensional breast scanning was performed using a breast-dedicated prototype laser scanner made up of a handheld device, including a charge-coupled device (CCD) camera coupled to a spot laser source. Two additional motion analyzer cameras were used for handheld device tracking and the acquisition of patient motion. Seven female volunteers, including both subjects who had undergone cosmetic or reconstructive breast surgery and those with no such history, underwent a dynamic breast shape survey. Curvature mapping on three-dimensional mesh warranted precise measurements of local geometric properties of the breast surface. Elaboration and representation of breast dynamic behavior during common motor tasks (eg, walking, running, sitting, and lying) was also possible. The scanning methodology reported here reliably describes the breast surface not only in a static position, but also at specific postures or during motion of the body. It also opens the door for quantitative static and dynamic assessment of surgical outcomes, the intraoperative assessment of breast shape, and other applications. Limitations include the relatively long amount of time required for each scan and the need for technical and clinical validation, particularly with respect to four-dimensional assessment.
    Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 29(6):505-8.