Michał Karlik

Poznan University of Medical Sciences, Poznań, Greater Poland Voivodeship, Poland

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Publications (19)8.31 Total impact

  • Article: Observations on hearing preservation in patients with hybrid-L electrode implanted at Poznan University of Medical Sciences in Poland.
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    ABSTRACT: The objective of the paper is to evaluate the hearing preservation rate in patients with high frequency hearing loss, treated with Cochlear Nucleus Freedom Hybrid-L implant in the Otolaryngology Department, Poznan University of Medical Sciences in Poland. Study was designed as the retrospective analysis. Twenty-one patients were operated and implanted with Nucleus Freedom Hybrid-L implant. Pure tone thresholds were recorded prior to the surgery and at the time of speech processor switch-on. Patients were subdivided into two groups with respect to their PTA thresholds: group A-classic indications and group B-extended indications. Average PTA for three frequencies (250, 500, 1,000 Hz) were calculated for each patient pre- and postoperatively. In the group of 21 implanted patients in 17 cases we have observed preservation of hearing (12 patients from group A, 5 patients from group B) with a mean value of 13.1 dB. In 4 out of 21 patients deafness on the implanted ear was noted. Our results clearly indicate that with standard procedure hearing preservation can be obtained in majority of patients. Hearing preservation was not achieved in 19 %, but owing to design of the electrode of the Cochlear Nucleus Hybrid-L that enables to work as CI platform alone, in patients who lost their hearing after surgery re-implantations were not required. This proves that EAS is a safe and reliable method to help patients with specific type of hearing loss.
    Archives of Oto-Rhino-Laryngology 12/2012; · 1.29 Impact Factor
  • Article: Erratum to: Simple technique for RNA purification from mouse inner ear hair cells.
    Molecular Biology Reports 04/2012; 39(4):5047. · 2.93 Impact Factor
  • Article: Simple technique for RNA purification from mouse inner ear hair cells.
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    ABSTRACT: Obtaining a good quality of RNA from small population of cells remain an issue. Isolation for a special anatomic location such as inner ear placed in the temporal bone become a challenge, especially in terms of time needed for isolation of living tissue from the bone, which is a key factor to preserve the RNA. Due to limited accessibility to the technologies such as laser dissection, we present a simplified procedure for isolation of good quality of RNA from the inner ear for further studies.
    Molecular Biology Reports 02/2012; 39(6):6467-9. · 2.93 Impact Factor
  • Article: [Comparison of different deafening strategies based on ototoxic drugs on mouse animals model].
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    ABSTRACT: To compare safety, reliability and usefulness of two deafening protocols on animal mouse model, based on aminoglycosides exposure Adults mice, Bulb/C, deafened with kanamycine 14 days treatment (group I), single kanamycin injection followed by etacrinic acid administration (group II) and control group. Hearing evaluation performed with ABR recordings on 6th day after drug exposure Both protocols were not able to guarantee complete ablation of the inner ear in tested animals. Although short deafening strategy was more effective (83.33% deaf mice) it was combined with high rate of mortality during general anesthesia for hearing evaluation. Variable outcomes in deafening mouse animal model implies the necessity of hearing evaluation every time prior to the pathophysiological as well as molecular studies. Mice exposed to severe oto- and nephrotoxic insult do not recover after anesthetic drug administration, thus harvesting inner ear tissues especially as the source of RNA should be performed immediately after ABR recordings.
    Otolaryngologia polska. The Polish otolaryngology 01/2012; 66(1):56-60.
  • Article: Polish universal neonatal hearing screening program-4-year experience (2003-2006).
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    ABSTRACT: The aim of this paper is to share our experience and observations in running the Universal Neonatal Hearing Screening Program on a national level, present results and indicate some problems that have arisen during these 4 years. Polish Universal Neonatal Hearing Screening Program started back in 2002 in all neonatal units in Poland. Implemented testing methods consisted of test of transient evoked otoacoustic emission (TEOAE) performed in all new born children in their first 2-3 days of life and auditory brainstem response testing (ABR) conducted on children, who did not meet the TEOAE pass criteria. Additional questionnaire registered information on ototoxic drugs and family history of hearing impairment in every newborn. Diagnosed children were further referred for treatment and rehabilitation. After 4 years of running the program (between 2003 and 2006) a total number of 1,392,427 children were screened for hearing impairment, what stands for 96.3% of all delivered babies, registered in Poland. The screening program enabled to identify and refer for further treatment 2485 children with various types of hearing loss, 312 with profound (0.02% of population) and 145 with severe sensorineural hearing loss (0.11% of population). Our results indicate the accuracy of newborn hearing screening which remain an issue. Although improvement is needed in both intervention systems and diagnostic follow-up of hospitals, the Polish Universal Neonatal Hearing Program fully has achieved the main goal, the identification and treatment of hearing impaired children.
    International Journal of Pediatric Otorhinolaryngology 11/2008; 72(12):1783-7. · 1.17 Impact Factor
  • Article: Comparison of rehabilitation results in deaf patients with and without genetically related hearing loss.
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    ABSTRACT: The introduction of prognostic tools to evaluate rehabilitation progress in cochlear implant patients (CI patients) is of great importance. The authors attempted to verify whether the identified 35delG mutation in the GJB2 gene can serve as a valuable indicator for rehabilitation progress of CI patients. A group of 51 subjects was studied. Molecular analysis was based on the identification of 35delG in GJB2. Logopedic assessment was performed with a non-verbal test of seven sounds, evaluating detection, discrimination and identification of the sounds during the first, third and sixth months after implantation. Results indicated that patients with GJB2-related deafness (DFNB1)s achieve better results in rehabilitation, but only at the early stages of rehabilitation. Prolonged rehabilitation equalised differences, which, subsequently, excluded this marker as an indicator for rehabilitation evaluation.
    Cochlear Implants International 10/2008; 9(3):132-42.
  • Article: [Universal neonatal hearing screening--parents view].
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    ABSTRACT: The aim of the study was to determine the parents view and attitude to the universal neonatal hearing screening. parents of randomly selected 200 infants, who underwent hearing rescreening, were surveyed using the authors questionnaire. the universal neonatal hearing screening and the way it is conducted is accepted by the vast majority of the parents in the region of Wielkopolska. The parents with higher social and economic status express their negative emotions associated with the organisation of hearing screening more often, their expectations towards the system of medical care are rising. the newborn hearing screening has been a good stimulus for parents intently observation of their child auditory reaction.
    Otolaryngologia polska. The Polish otolaryngology 02/2006; 60(5):753-6.
  • Article: [Cochlear implantation in visually impaired patients--long-term rehabilitation results].
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    ABSTRACT: The aim of the study was to assess the rehabilitation results in visually impaired patients with cochlear implants. Material consisted of 9 patients (2 with prelingual deafness, 3 with perilingual deafness, 4 with postlingual deafness) from 244 implanted persons in Poznań. METHODS: In all the patients the rehabilitation results were evaluated using Test of Auditory Perception of Speech (TAPS) and screening test. RESULTS: In the group of patients with pre- and perilingual deafness a little bit slower progress of rehabilitation was found, according to 117 persons with prelingual deafness and 34 persons with perilingual deafness without vision disorders. Within the group of patients with postlingual deafness important progress of rehabilitation was observed. Two brothers with Usher syndrome 1-2 months after speech processor switch-on reached the highest level of test, they could communicate with family. One person after 5 months of rehabilitation could talk by phone without any problems. In all implanted visually impaired patients improvement of auditory perception of speech was observed.
    Otolaryngologia polska. The Polish otolaryngology 02/2005; 59(3):415-9.
  • Article: [Voice disorders in rheumatoid arthritis].
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    ABSTRACT: The report presents three patients with coincidence of voice disorders and rheumatoid arthritis. Material consisted of 3 females aged 39, 48 and 74 years. Methods included phoniatric examination, videolaryngoscopy, stroboscopy and acoustic voice analysis MDVP). Results: In the two youngest patients the laryngoscopic changes were located on vocal folds, mostly as yellow nodules. The appropriate mobility of both vocal folds was found. The MDVP analysis particularly revealed changes in parameters describing perturbation of amplitude in both cases. In the third case oedema in the region of the crico-arytenoid joints and vestibular folds were observed. MDVP analysis showed slight disturbances in the parameters describing frequency perturbation.
    Otolaryngologia polska. The Polish otolaryngology 02/2005; 59(4):603-6.
  • Article: [Contraindication for cochlear implantation in Wildervanck's syndrome].
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    ABSTRACT: A case of 4-year-old boy with Wildervanck's syndrome and associated profound sensorineural hearing loss is presented. The child was disqualified from cochlear implantation following the CT scan of petrous pyramids which revealed inner ear malformation. The authors emphasize role of CT imaging in the management of profound sensorineural hearing loss in children before final qualification for cochlear implantation.
    Otolaryngologia polska. The Polish otolaryngology 02/2004; 58(4):803-6.
  • Article: [Poznań's program of cochlear implantation: 10 years experience].
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    ABSTRACT: The first cochlear implant in the ENT Department in Poznań was introduced in adult patient in January 1994. One year later the first deaf child was implanted. During 10 years over 200 deaf people were operated on. Modifications of diagnostics, surgery and rehabilitation were presented. Lowering the age of the implantation, changes of audiological criteria, genetic diagnostic and possibility of implantation in multi-handicapped patients were emphasized. Almost all surgeries were performed through the posterior tympanotomy and in one cases through the middle fossa approach. In one child with total ossification in CT scans Nucleus Double Array was used. Speech rehabilitation bases on auditory-verbal therapy. Rehabilitation consists of individual sessions with speech therapist and group therapy. Logorytmics exercises were introduced.
    Otolaryngologia polska. The Polish otolaryngology 02/2004; 58(1):37-43.
  • Article: [The changes in the distinctness and discrimination of phonems of cochlear implants children].
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    ABSTRACT: Hearing impaired children do not develop oral speech in the same time with the hearing ones. Cochlear implants may change this situation. Implanted deaf children may develop oral speech but only after long speech rehabilitation. Acquisition of language skills should be assesed correctly in every patient. It is important because this therapy is quite expensive. There are many quantitative and qualitative methods used all over the world. In some cases score is calculated as percentage of correctly repeated words. Sometimes it did not reflect true level of language development. 240 people were implanted in Poznań in years 1994-2004. Two years ago, evaluation of changes in the distinctness and discrimination of phonems of cochlear implants children was begun. We found differences between standard speech audiometry and distinctness and discrimination of phonems.
    Otolaryngologia polska. The Polish otolaryngology 02/2004; 58(5):965-70.
  • Article: [Quality of life in children with cochlear implants and their families (Program Schwarzenberg)--initial report].
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    ABSTRACT: The aim of the study was to present the results of international evaluation program "Quality of Life in children and their families--Schwarzenberg Initiative". The parents of children under 15 years old was asked to fill out specially prepared questionnaires. 1240 children from 9 countries participated in the study. In Poland 60 families filled out the questionnaires. 80 questions concerned several topics, including reaction of parents to the first information about impaired hearing of their child, using hearing aids before and after implantation, evaluation of behaviour in kindergarten and in school. This initial report describes only a few important topics. In 27.7% of Polish families the impaired hearing of their child was a cause to stop the work of one of the parents, to decrease time of work or to change the place of work in 9.1%. In most of the children the perception of sound was noticed. Only a few families from Austria, Slovenia, Swiss and Italy reported unsatisfactory results after implantation. Implantation increases quality of life of implanted children and their families.
    Otolaryngologia polska. The Polish otolaryngology 02/2004; 58(3):535-9.
  • Article: [Enlarged vestibular aqueduct syndrome in patients with hypoacusis and deafness].
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    ABSTRACT: In 1978 Valvassori and Clemis have reported that enlarged vestibular aqueduct can cause progressive perceptive hearing loss and finally deafness. AIM: Analysis of CT scans of patients with cochlear implants. Analysis of radiological data of 120 implanted patients was performed. CT examinations were performed during qualification to cochlear implantation. Most of the CT scans were performed using high resolution computed tomography (HRCT). A special attention was paid to patients with progressive perceptive hearing loss and CT of two patients with "gusher" during CI surgery. In one case (6-years old girl with bilateral profound perceptive hearing loss diagnosed in 2nd year of age) an enlarged vestibular aqueduct was found radiologically. In the second case (16 years old girl with progressive perceptive hearing loss since 1st year of age) no enlarged vestibular aqueduct was detected. Diagnostics and treatment of enlarged vestibular aqueduct syndrome are presented.
    Otolaryngologia polska. The Polish otolaryngology 02/2003; 57(4):497-500.
  • Article: [Preliminary results of objective audiological assessment of children with hearing impairment selected in neonatal hearing screening].
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    ABSTRACT: The aim of the paper was to present the results of the objective audiological assessment of 48 babies and infants at the age of 1-16 months, referred the Department of Phoniatrics and Audiology in Poznań (Poland) from January 2001 to July 2002. The children were selected in neonatal hearing screening, based on the OAE, questionnaire of hearing loss with high risk factors. We discuss high percentage of false positive results of OAE, late referrals for hearing screening, difficulties of follow-up.
    Otolaryngologia polska. The Polish otolaryngology 02/2003; 57(4):531-5.
  • Article: [Usefulness of TAPS (Polish version) for evaluation of CI children's progress in speech rehabilitation--7 years of observation].
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    ABSTRACT: The speech rehabilitation of pre- and perilingually deafened children with cochlear implants it is a very long process. It should be individualized for needs of every young patient. It is possible only after correct evaluation of speech level. There are many tests for this evaluation. Among them same are more known like TAPS test. Test of Auditory Perception of Speech (TAPS) was elaborated in English at Basel University in Swiss. It was translated to Polish at Adam Mickiewicz University and Karol Marcinkowski University School of Medical Sciences in Poznań. The authors present their own 7-years observations.
    Otolaryngologia polska. The Polish otolaryngology 02/2003; 57(2):251-5.
  • Article: [Two cases of rare unilateral sensorineural hearing loss].
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    ABSTRACT: We report a case of unilateral sensorineural hearing loss due to Borrelia burgdorferi infection and in a patient with haemophilia B and hepatitis C treated with alpha-interferon. An audiological check-up of that kind of patients is indicated in order to exclude hearing loss.
    Otolaryngologia polska. The Polish otolaryngology 02/2003; 57(1):115-9.
  • Article: [Distinctness and discrimination of phonemes in children with cochlear implants--preliminary report].
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    ABSTRACT: There are many tests prepared for speech evaluation for different age groups and with any disabilities. The percent of correct repeated mono- or bisyllabes words create the final result. Sometimes this score is lower than real oral communication skill of CI patient. In the years 1994-2002 in Poznań 158 cochlear implantations were performed. Since few months the evaluation of the distinctness and discrimination of phonems of cochlear implants children are being conducted. It was found some differences between distinctness and discrimination of phonems and discrimination of words. It means that scores achieved by children in standarized words--tests do not reflect the real level of speech development of each child.
    Otolaryngologia polska. The Polish otolaryngology 02/2003; 57(1):109-13.
  • Article: [Olfaction in congenital hypothyroidism].
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    ABSTRACT: The aim of the study is to present results of the olfactory testing in congenital hypothyroidism in the group of 20 subjects. The etiology of hypothyroidism included: Pendred's syndrome in 2 cases, hypoplasia in 2 cases, athyreosis in 5 cases and ectopy of thyroid gland in 11 cases. Olfactory testing involved olfactometry by Elsberg-Levy modified by Pruszewicz for 4 odorants: coffee, lemon, mint and anise; smell fatigability test by Pruszewicz et al. for lemon. Level of plasma TSH was determined in each subject. Age of the subjects, at which hormonal replacement therapy was started and regularity of the treatment were taken into consideration. Obtained results: impaired odorant identification and shortened smell fatigability period prove a significant impact of thyroid status on central nervous system development most probably already prior to birth and on cognition processes.
    Otolaryngologia polska. The Polish otolaryngology 02/2002; 56(5):577-81.