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F. Frauscher,
A. Klauser,
A. P. Berger,
E. J. Halpern, G. Feuchtner,
F. Koppelstaetter,
L. Pallwein,
G. M. Pinggera,
H. Weirich,
W. Horninger,
G. Bartsch,
D. zur Nedden
[show abstract]
[hide abstract]
ABSTRACT: Die Sonographie der Prostata zeigt eine zunehmende Bedeutung, welche sich in erster Linie durch die steigende Inzidenz des
Prostatakarzinoms, dem häufigsten Malignom des Mannes, ergibt. Die Prostatasonographie ist das bildgebende Verfahren der ersten
Wahl in der Abklärung von Prostataerkrankungen. Die Wertigkeit der konventionellen transrektalen B-Bild-Sonographie wurde
intensiv evaluiert. Dieser Beitrag soll insbesondere neue Ultraschalltechnologien zur Detektion des Prostatakarzinoms darstellen.
Die farbkodierte Duplexsonographie, Powerdopplersonographie nativ und mit Anwendung von Ultraschallkontrastmitteln (Echosignalverstärker)
haben neue Möglichkeiten zur Früherkennung des Prostatakarzinoms eröffnet, bzw. bieten auch wertvolle Information sowohl in
der präoperativen Abklärung als auch in der therapeutischen Verlaufskontrolle. Die Anwendung von Ultraschallkontrastmitteln
mit neuen Ultraschalltechnologien (z. B. “B-Bild-Harmonic-Sonographie”) scheint eine weitere Verbesserung des diagnostischen
Potenzials zu ermöglichen. Weiterführende Studien sind jedoch notwendig, um den eindeutigen klinischen Stellenwert der derzeitig
sehr erfolgversprechenden kontrastmittelverstärkten Sonographie zu evaluieren.
The value of ultrasound (US) in the diagnosis of prostate cancer has increased in importance in the past decade, which is
mainly related due to the increasing incidence of prostate cancer, the most common malignancy in men. The value of conventional
gray-scale US for prostate cancer detection has been extensively investigated. The introduction of US contrast agents has
dramatically changed the role of US for prostate cancer detection. Advances in US techniques were introduced to further increase
the role of US contrast agents. Although most of these advances in US techniques, which use the interaction of the contrast
agent with the transmitted US waves are very sensitive for the detection of microbubbles, are mostly unexplored, in particular
for prostate applications. First reports of contrast-enhanced US investigations of blood flow of the prostate have shown that
contrast-enhanced US adds important information to the conventional US technique. We present a critical evaluation of the
current status of transrectal US imaging for prostate cancer detection. Furthermore, we give background information on US
contrast agents and imaging modalities. Early results of contrast-enhanced US suggest the feasibility of the use of US contrast
agents to enhance US imaging of the prostate. The application of US contrast agents for the detection and clinical staging
of prostate cancer is promising. However, future clinical trials will be needed to determine the promise of contrast-enhanced
US of the prostate evolves into clinical application.
Der Radiologe 04/2012; 43(6):455-463. · 0.61 Impact Factor
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ABSTRACT: Acute chest pain is a common symptom but triage decisions in these patients remain a challenge. Patient's history, cardiac enzyme levels, or electrocardiograms often are unspecific. Nowadays, multidetector-row computed tomography (CT) currently represents the imaging modality of choice for diagnosing or excluding pulmonary embolism (PE) or acute aortic syndrome (AAS). Furthermore, recent studies have demonstrated advantages for non-invasive imaging of the coronary arteries by CT. The so called triple rule-out CT allows the depiction of the pulmonary arteries, the thoracic aorta, and the coronary arteries within a single examination with a simultaneous attenuation of these three vessel territories. This enables the detection of life-threatening such as PE, AAS and ACS, as well as of non-life-threatening diseases causing acute chest pain.
Praxis 04/2010; 99(9):545-52.
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[show abstract]
[hide abstract]
ABSTRACT: Real-time sonoelastography (SE), a newly introduced ultrasound technique, has already shown conclusive results in breast, prostate, and thyroid tumor diagnostics. This study investigated the performance of SE for the differentiation of Achilles tendon alterations of tendinopathy compared to clinical examination and conventional ultrasound (US).
Achilles tendons in 25 consecutive patients with chronic Achilles tendinopathy and 25 healthy volunteers were examined clinically by US and by SE.
In the healthy volunteers, SE showed the tendon to be hard (93 %), while distinct softening was found in 57 % of the patients. SE showed more frequent involvement of the distal (64 %) and middle third (80 %) than the proximal third (28 %) of the Achilles tendon. Using SE a mean sensitivity of 94 %, specificity of 99 %, and accuracy of 97 % were found when clinical examination was used as the reference standard. The correlation to US was 0.89. Mild softening was found in 7 % of the healthy volunteers and in 11 % of the patients.
Our results emphasize that only distinct softening of Achilles tendons is comparable to clinical examination and US findings. However, mild softening might be explained by very early changes in tissue elasticity in the case of Achilles tendinopathy, which should be assessed in follow-up studies.
Ultraschall in der Medizin 11/2009; 31(4):394-400. · 2.40 Impact Factor
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ABSTRACT: Inflammatory processes may increase the urothelial thickness of the renal pyelon. Purpose of the study was to assess sonographic measurement of pyelon wall thickness (PWT) in adult patients with acute pyelonephritis, chronic urinary tract infection (UTI) and indwelling ureteral stents.
Four study groups (acute pyelonephritis n=50, chronic UTI n=10, indwelling ureteral stents n=10, controls n=25) underwent renal ultrasonography (Acuson Seqouia, Mountain View, CA; 6 MHz Transducer). The renal pyelon was imaged in transverse and longitudinal planes. PWT measurements of patients with acute pyelonephritis were repeated after successful antibiotic treatment.
Mean PWT in healthy controls was 1.0 mm+/-0.19. In patients with acute pyelonephritis, PWT was significantly increased to 2.9 mm+/-0.89 (p<0.001). PWT decreased significantly after antibiotic treatment to 1.4 mm+/-0.47 (p<0.001). Kidneys with indwelling stents presented with a PWT of 2.7 mm+/-0.68, kidneys with chronic UTI demonstrated a PWT of 2.8 mm+/-0.62. PWT in these patient groups was significantly greater than PWT in healthy volunteers (p<0.001). The interobserver agreement was excellent (p<0.001).
PWT is a reproducible diagnostic criterion for acute pyelonephritis. Based upon our experience, we suggest a cut-off value of 2.0 mm to distinguish healthy kidneys from those with urothelium thickened by inflammation. PWT cannot be used to distinguish acute pyelonephritis from chronic inflammation of the urothelium.
Ultraschall in der Medizin 01/2008; 28(6):593-7. · 2.40 Impact Factor
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F Frauscher,
A Klauser,
A P Berger,
E J Halpern, G Feuchtner,
F Koppelstaetter,
L Pallwein,
G M Pinggera,
H Weirich,
W Horninger,
G Bartsch,
D zur Nedden
[show abstract]
[hide abstract]
ABSTRACT: The value of ultrasound (US) in the diagnosis of prostate cancer has increased in importance in the past decade, which is mainly related due to the increasing incidence of prostate cancer, the most common malignancy in men. The value of conventional gray-scale US for prostate cancer detection has been extensively investigated. The introduction of US contrast agents has dramatically changed the role of US for prostate cancer detection. Advances in US techniques were introduced to further increase the role of US contrast agents. Although most of these advances in US techniques, which use the interaction of the contrast agent with the transmitted US waves are very sensitive for the detection of microbubbles, are mostly unexplored, in particular for prostate applications. First reports of contrast-enhanced US investigations of blood flow of the prostate have shown that contrast-enhanced US adds important information to the conventional US technique. We present a critical evaluation of the current status of transrectal US imaging for prostate cancer detection. Furthermore, we give background information on US contrast agents and imaging modalities. Early results of contrast-enhanced US suggest the feasibility of the use of US contrast agents to enhance US imaging of the prostate. The application of US contrast agents for the detection and clinical staging of prostate cancer is promising. However, future clinical trials will be needed to determine the promise of contrast-enhanced US of the prostate evolves into clinical application.
Der Radiologe 07/2003; 43(6):455-63. · 0.61 Impact Factor
