M Malvaso

Publications (4)2.88 Total impact

• Article: [Treatment with low-dose HGH in children of short stature due to somatotropin deficiency].

  G Scirè, G L Spadoni, M Malvaso, A Scalamandrè, B Bacchielli, M L Manca Bitti
  Minerva pediatrica 07/1983; 35(12):633-8.
• Article: [Blood platelet oxygen consumption in pituitary dwarfs (author's transl)].

  D Del Principe, B Boscherini, A Menichelli, O Giardini, F Mastracchio, M Malvaso, M Gabriotti, G L Spadoni
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  ABSTRACT: Oxygen consumption in blood platelets of 14 pituitary dwarfs aged from 2 to 8 years was investigated before and after a 2 months' treatment with growth hormone (GH). No significant difference was found between dwarfs and control subjects in respect of basal platelet oxygen uptake (4.0 +/- 3.8 mmol O2/10(9) platelets/min in dwarfs as against 6.4 +/- 4.1 in controls), but the abrupt increase in oxygen consumption induced by thrombin was significantly reduced in dwarfs (4.3 +/- 4.1) as compared with controls (12.3 +/- 7.6; p less than 0.01). During GH treatment, however, the dwarfs' response to thrombin stimulation was similar to that of controls. Since dwarfs had normal platelet malonyldialdehyde production, it is likely that the mitochondrial component of thrombin-induced high oxygen consumption was deficient. These results suggest that blood platelets may contribute to the protective effect of GH deficiency against atherosclerosis.
  La Nouvelle presse médicale 06/1981; 10(24):2015-7.
• Source

  Available from: Anna Maria Pasquino

  Article: Hypothalamic-pituitary-gonadotropic function in girls with premature thelarche.

  A M Pasquino, F Piccolo, A Scalamandre, M Malvaso, R Ortolani, B Boscherini
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  ABSTRACT: Hypothalamic-pituitary-gonadotropic activity was investigated in 9 girls with premature thelarche, and compared with that in 9 healthy girls and 6 girls with true precocious puberty. The gonadotropin stimulation test with luteinising hormone-releasing hormone was used. Girls with premature thelarche showed luteinising hormone response resembling that of normal girls, and follicle-stimulating hormone (FSH) response quite similar to that of girls with precocious puberty. This suggests that in premature thelarche there is a partial activation of the diencephalic-hypophyseal-gonadal axis, which affects FSH only. Premature thelarche therefore, should be considered as one of the disorders due to altered sensitivity of the hypothalamic receptors which regulate sex maturation.
  Archives of Disease in Childhood 01/1981; 55(12):941-4. · 2.88 Impact Factor
• Article: [Evaluation of neurologic and mental development in children with congenital hypothyroidism treated after the first month of life (author's transl)].

  M L Manca Bitti, V Quintè, E Benatouil, S Conti, M Malvaso, P Panei, G L Spadoni
  La Pediatria medica e chirurgica: Medical and surgical pediatrics 3(6):507-10.