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ABSTRACT: Traumatic rupture of the diaphragm (TRD) is a rare occurrence, with variable morbidity and mortality. The aim of this study was to analyze cases of TRD in a tertiary hospital and assess prognostic factors associated with mortality.
A retrospective study was performed of patients diagnosed with TRD in Hospital Universitario La Fe, Valencia, Spain, between 1969 and 2006. The following variables were analyzed: sex, age, cause, diagnosis, associated lesions, surgical procedure, side and size of the lesion, visceral herniation, and postoperative morbidity and mortality.
The study group comprised 132 patients (105 men, 79.5%) with a mean (SD) age of 39.64 (17.04) years. Traffic accidents were the most common cause of TRD. Rupture involved the left hemidiaphragm in 96 cases (72.7%), and 113 patients (85.6%) had associated lesions, most often affecting the abdomen. Thoracotomy was performed in 83 cases (62.9%) and laparotomy in 41 (31.1%). Visceral herniation was reported in 90 patients (68.3%), most often involving the stomach. The rates of perioperative morbidity and mortality were 62.8% and 20.5%, respectively. Diagnostic delay and the presence of morbidity and serious associated lesions all had a statistically significant impact on mortality (P< .05). In the case of serious associated lesions, the odds ratio was 2.898 (95% confidence interval, 1.018-8.250) and for perioperative morbidity it was 1.488 (95% confidence interval, 1.231-1.798).
TRD is an infrequent occurrence in young men, is generally caused by traffic accidents, and is more common on the left side. Associated lesions are present in most cases and represent the main prognostic factor affecting morbidity and mortality. TRD can be considered a relative surgical emergency when not accompanied by other lesions that in themselves constitute surgical emergencies.
Archivos de Bronconeumología 04/2008; 44(4):197-203. · 2.17 Impact Factor
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Archivos de Bronconeumología 02/2005; 41(1):59. · 2.17 Impact Factor
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The Journal of cardiovascular surgery 11/2004; 45(5):525. · 1.56 Impact Factor
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ABSTRACT: We report five cases of thyroid carcinoma with tracheal invasion. In two patients infiltration was found during thyroid exeresis. Diagnosis was based on respiratory signs such as hemoptysis and stridor in the other three patients. The pathologic diagnosis was papillary carcinoma for four patients and follicular carcinoma for one, the only man in the series. Treatment by thyroidectomy, tracheal resection and end-to-end anastomosis with node removal was followed by long-term survival. A search for tracheal involvement during thyroidectomy and clinical suspicion were the keys to a good prognosis for these patients.
Archivos de Bronconeumología 12/2002; 38(11):542-4. · 2.17 Impact Factor
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Archivos de Bronconeumología 02/2002; 38(1):55-6. · 2.17 Impact Factor
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ABSTRACT: This study aimed to validate in our population changes in the stage II criteria for non-small cell bronchogenic carcinoma.
We retrospectively reviewed and followed the course of disease in 336 patients who underwent complete resection in our hospital between January 1969 and December 1995 with stage II disease, classified as T1N1M0 (41), T2N1M0 (144) and T3N0M0 (151).
The expected five-year survival in our population was 43.19 +/- 2.90%. Estimated mean survival was 3 +/- 0.71 years (95% confidence interval: 1.60-4.40). Mean survival was 8.82 +/- 0.67 years (95% confidence interval 7.51-10.13). Five-year survival was 53.32 +/- 8.55% for tumors classified as T1N1M0, 38.57 +/- 4.40% for T2N1M0, and 44.46 +/- 4.30% for T3N0M0. We observed significant differences in survival depending on histological type, tumor size, and IIA or IIB staging, degree of tumor invasion (T), number of nodes involved (N1) and location. T3N0M0 tumors displayed great variation in expected survival rates in relation to structures involved (27.53% to 59.98%). Multivariate analysis confirmed degree of tumor invasion, size and histological type to be the main prognostic factors.
We conclude that the new staging system gives a more realistic prognosis for patients in our practice. The stage IIA and IIB division is appropriate and gives significantly different prognoses. However, the T3N0M0 category is heterogeneous and is not significantly different from T1-2N1M0, such that stage II overall continues to be an indivisible, homogeneous group of patients. Other prognostic variables, such as histological type, affect survival in our patients.
Archivos de Bronconeumología 02/2001; 37(1):19-26. · 2.17 Impact Factor
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ABSTRACT: We analyzed the survival after surgery for non-small cell lung cancer (NSCLC) classified as T3N0. Between January 1969 and 1995, 151 patients underwent surgery for NSCLC in our hospital. Survival analysis was performed using the Kaplan-Meier statistical method and the curves were compared using Mantel-Cox, Breslow and Tarone-Ware tests. The estimated five-year survival in the studied population was 44.46 +/- 4.30%. Four groups were defined based on degree of tumoral invasion of mediastinal structures, parietal pleura, chest wall or superior sulcus. Significant differences in five-year survival were observed between groups. Patients in the mediastinal group (59.98 +/- 8.71%) had the best prognosis, followed by patients with parietal pleura involvement (52.79 +/- 6.69%). Survival in the chest wall group was 27.53 +/- 7.22%. No patients with superior sulcus tumors survived over five years (median survival 1.50 +/- 1.16 years; 95% confidence interval 0.00 to 3.77 years). Prognosis is clearly determined by degree of tumoral invasion in T3N0 patients. In spite of the evident conceptual improvements achieved with the revised International Staging System, the system still fails to fully define prognosis in such cases.
Archivos de Bronconeumología 11/2000; 36(9):510-4. · 2.17 Impact Factor
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Archivos de Bronconeumología 11/1999; 35(10):512. · 2.17 Impact Factor
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ABSTRACT: ObjectiveTraumatic rupture of the diaphragm (TRD) is a rare occurrence, with variable morbidity and mortality. The aim of this study was to analyze cases of TRD in a tertiary hospital and assess prognostic factors associated with mortality.Patients and methodsA retrospective study was performed of patients diagnosed with TRD in Hospital Universitario La Fe, Valencia, Spain, between 1969 and 2006. The following variables were analyzed: sex, age, cause, diagnosis, associated lesions, surgical procedure, side and size of the lesion, visceral herniation, and postoperative morbidity and mortality.ResultsThe study group comprised 132 patients (105 men, 79.5%) with a mean (SD) age of 39.64 (17.04) years. Traffic accidents were the most common cause of TRD. Rupture involved the left hemidiaphragm in 96 cases (72.7%), and 113 patients (85.6%) had associated lesions, most often affecting the abdomen. Thoracotomy was performed in 83 cases (62.9%) and laparotomy in 41 (31.1%). Visceral herniation was reported in 90 patients (68.3%), most often involving the stomach.The rates of perioperative morbidity and mortality were 62.8% and 20.5%, respectively. Diagnostic delay and the presence of morbidity and serious associated lesions all had a statistically significant impact on mortality (P<.05). In the case of serious associated lesions, the odds ratio was 2.898 (95% confidence interval, 1.018-8.250) and for perioperative morbidity it was 1.488 (95% confidence interval, 1.231-1.798).ConclusionsTRD is an infrequent occurrence in young men, is generally caused by traffic accidents, and is more common on the left side. Associated lesions are present in most cases and represent the main prognostic factor affecting morbidity and mortality. TRD can be considered a relative surgical emergency when not accompanied by other lesions that in themselves constitute surgical emergencies.ObjetivoLa rotura diafragmática traumática (RDT) es una lesión infrecuente, con tasas variables de morbimortalidad. El objetivo del estudio ha sido analizar la experiencia en RDT de un hospital terciario y los factores pronósticos de mortalidad.Pacientes y métodosSe ha realizado un estudio analítico y retrospectivo de los pacientes diagnosticados de RDT entre 1969 y 2006 en el Hospital La Fe. Se analizaron: sexo, edad, causa, diagnóstico, lesiones asociadas, procedimiento quirúrgico, lado y tamaño, herniación visceral y morbimortalidad postoperatoria.ResultadosSe incluyó en el estudio a 132 pacientes (105 varones; 79,5%) con una edad media ± desviación estándar de 39,64 ± 17,04 años. Los accidentes de tráfico fueron la causa más frecuente de RDT. En 96 casos (72,7%) se afectó el hemidiafragma izquierdo y 113 pacientes (85,6%) asociaron lesiones, de las cuales las abdominales fueron las más frecuentes. Se abordaron por toracotomía 83 casos (62,9%) y por laparotomía 41 (31,1%). En 90 pacientes (68,3%) se evidenció herniación visceral, siendo el estómago la más frecuente.Las tasas de morbilidad y mortalidad perioperatorias fueron del 62,8 y el 20,5%, respectivamente. La presencia de morbilidad y de lesiones asociadas graves, y el retraso diagnóstico tuvieron un impacto significativo en la mortalidad (p < 0,05. Lesiones graves: odds ratio = 2,898; intervalo de confianza del 95%, 1,018-8,250. Morbilidad perioperatoria: odds ratio = 1,488; intervalo de confianza del 95%, 1,231-1,798).ConclusionesLa RDT es una entidad infrecuente que se da en varones jóvenes, generalmente por accidentes de tráfico, y es más frecuente en el lado izquierdo. Las lesiones asociadas están presentes en la mayoría de los casos y son el principal factor pronóstico que condiciona la morbimortalidad. La RDT puede considerarse una urgencia quirúrgica diferida, en ausencia de otras lesiones que constituyan una urgencia quirúrgica en sí mismas.
Archivos de Bronconeumología ((English Edition)).
