Kyung Seek Choi

Soonchunhyang University, Onyang, South Chungcheong, South Korea

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Publications (32)38.19 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: To assess the changes in diabetic retinopathy (DR) in Type 2 diabetes (T2DM) patients after bariatric surgery. Consecutive 20 patients with T2DM who underwent bariatric surgery and were followed for at least 12 months were enrolled. The case history was reviewed retrospectively, and laboratory data were assessed at baseline and every 3 months postoperatively. Two retinal specialists evaluated the severity of DR with dilated fundus examination preoperatively and postoperatively. Factors associated with DR progression were assessed. During the follow-up period, 2 of 12 patients without DR and 2 of 3 patients with mild nonproliferative DR before surgery developed moderate nonproliferative DR. All five patients with moderate nonproliferative DR or worse preoperatively had progression requiring intervention. Preexisting DR (P = 0.005) and albuminuria (P = 0.01) were identified as associated with DR progression. Six patients (30%) entered remission of T2DM, but remission of T2DM could not halt the DR progression. Diabetic retinopathy progression can occur in patients with or without before DR after bariatric surgery, regardless of remission of T2DM. All patients with T2DM should be examined regularly by an ophthalmologist postoperatively, and more carefully patients with previous DR or albuminuria.
    Retina 01/2015; · 3.18 Impact Factor
  • Yong Joon Kim, Bo Mi Choi, Kyung Seek Choi
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    ABSTRACT: Granulicatella elegans is a normal component of the oral flora and is an unusual causative agent of infective endocarditis. A case of G. elegans periorbital infection of the eyelid after dental treatment is reported. A healthy 35-year-old man presented with painful swelling of the left upper eyelid. He was empirically treated with oral amoxicillin for 1 week. He presented 3 months later with the same clinical features. G. elegans and Staphylococcus epidermidis were identified in bacterial cultures from wound aspirates. Probable relapse of periorbital infection was successfully treated with a 6-week course of oral amoxicillin. This is the first reported case of a non-bloodstream infection caused by G. elegans. Clinicians should be aware of G. elegans as an unusual causative agent of periorbital infection. Within the limitations of this case report, prolonged antibiotic therapy is recommended for a G. elegans periorbital infection to minimize the risk of relapse.
    Ophthalmic Plastic and Reconstructive Surgery 08/2014; · 0.91 Impact Factor
  • Yong Joon Kim, Kyung Seek Choi
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    ABSTRACT: Abstract Purpose: The purpose of this study was to measure the pressure difference between the anterior chamber (AC) and the vitreous cavity (VC) in eyes with and without pupillary block. Materials and methods: Seven vitrectomized porcine eyes were used. Infusion pressures of 10-80 mmHg were generated with a vented gas forced infusion system. Measurements of pressure were obtained with digital manometry connected to 25-gauge catheters from the AC and VC simultaneously. After increasing AC pressure to each target pressure, VC pressure was recorded, and vice versa. Inspection was performed with portable slit-lamp biomicroscopy to identify the development of pupillary block at the end of each experiment. Results: When the AC pressure was increased, the VC pressure obtained was similar to the AC pressure in all cases. When the VC pressure increased, the AC pressure obtained was similar to that at a VC pressure of less than 50 mmHg. When the VC pressure was increased rapidly to 60, 70, and 80 mmHg, the AC pressures obtained were 57.6 ± 1.0, 64.0 ± 0.8, and 69.6 ± 2.4 mmHg, respectively. Thus, the VC pressures obtained were 1.5, 5.9, and 9.1 mmHg higher than pressures obtained from AC with target pressures of 60, 70, and 80 mmHg, respectively (p = 0.027, 0.001, and 0.001, respectively). Pupillary block was observed in cases where the VC pressure was increased to more than 50 mmHg. Conclusions: The AC pressure could be significantly lower than the VC pressure in some eyes with pupillary block.
    Current Eye Research 07/2014; · 1.66 Impact Factor
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    ABSTRACT: Purpose: To comprehend the mechanism of focal chorioretinal damage by analysis of the pressure distribution and dynamic pressure induced by infused air during fluid-air exchange. Methods: A precise simulation featuring a model eye and a fluid circuit was designed to analyze fluid-air exchange. The pressure distribution, flow velocity, and dynamic pressure induced by infusion of air into an air-filled eye were analyzed using an approach based on fluid dynamics. The size of the port and the infusion pressure were varied during simulated iterations. We simulated infusion of an air-filled eye with balanced salt solution (BSS) to better understand the mechanism of chorioretinal damage induced by infused air. Results: Infused air was projected straight toward a point on the retina contralateral to the infusion port (the "vulnerable point"). The highest pressure was evident at the vulnerable point, and the lowest pressure was recorded on most retinal areas. Simulations using greater infusion pressure and a port of larger size were associated with elevations in dynamic pressure and the pressure gradient. The pressure gradients were 2.8 and 5.1 mmHg, respectively, when infusion pressures of 30 and 50 mmHg were delivered through a 20-gauge port. The pressure gradient associated with BSS infusion was greater than that created by air, but lasted for only a moment. Conclusions: Our simulation explains the mechanism of focal chorioretinal damage in numerical terms. Infused air induces a prolonged increase in focal pressure on the vulnerable point, and this may be responsible for visual field defects arising after fluid-air exchange.
    Investigative Ophthalmology &amp Visual Science 05/2014; · 3.66 Impact Factor
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    Jee Wook Kim, Kyung Seek Choi
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    ABSTRACT: We aimed to quantify the displacement of macular capillaries using infrared fundus photographs and image processing software (ImageJ) in patients with idiopathic epiretinal membrane (ERM) who have undergone vitrectomy and to analyze the correlation between vessel displacement and retinal thickness. This prospective study included 16 patients who underwent vitrectomy for idiopathic ERM. Ophthalmic examination and optical coherence tomography (OCT) were performed before and 3 months after surgery. The length of radial vessel segment included in each area (VLA) and the length from the foveola to the vessel branching point (FBL) depending on the superior, inferior, nasal, and temporal areas of the macula were measured using infrared fundus images and image processing software (ImageJ). Preoperative and postoperative parameters were compared and correlations between VLA, FBL, macular thickness, and visual acuity were assessed. The VLA of superior, inferior, and temporal areas showed a significant postoperative reduction. VLA differences showed a positive correlation with differences in macular thickness, which corresponded to the superior, inferior, and temporal areas; however, no correlation was observed in the nasal area. The FBL of the superior and inferior areas was significantly increased postoperatively. A positive correlation was observed between FBL differences and macular thickness differences in the superior area. Postoperative change in VLA and FBL did not show a significant correlation with postoperative best corrected visual acuity (BCVA) and BCVA differences. Infrared fundus photographs and image processing software can be useful for quantifying progressive changes in retinal surface distortion after surgical removal of ERM. Macular edema and vascular distortion showed significant improvement after surgery. Furthermore, a correlation was observed between topographic and tomographic changes.
    BMC Ophthalmology 04/2014; 14(1):51. · 1.08 Impact Factor
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    Donghyun Wang, Kyung Seek Choi, Sung Jin Lee
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    ABSTRACT: This study compared serum vascular endothelial growth factor (VEGF) concentration between patients given the bilateral and unilateral intravitreal injections of bevacizumab. In a prospective manner, serum VEGF levels in treatment-naive patients with age-related macular degeneration who underwent bilateral or unilateral intravitreal injections of bevacizumab were investigated. After informed consent, peripheral blood was collected from in patients who underwent bilateral or unilateral intravitreal injection of bevacizumab before and 1 month after the injection. Serum VEGF levels were measured by enzyme-linked immunosorbent assay after centrifugation. In addition, best-corrected visual acuity (BCVA) and central retinal thickness (CRT) before and 1 month after the injection were compared between each group. Twenty patients received bilateral injections (40 eyes) and 20 patients received unilateral injections. The VEGF concentrations (pg/mL) before the bilateral injection were 235.75 ± 183.16 and 252.53 ± 233.52 for the unilateral injection. They were significantly reduced to 153.88 ± 113.26 and 189.42 ± 251.72 after 1 month, respectively (p = 0.037 and 0.019), which are showing no significant difference between the two groups (p = 0.771). And there were no significant intergroup difference in pre- and postoperative BCVA and CRT. The bilateral simultaneous intravitreal injection of bevacizumab did not differ greatly from unilateral intravitreal injection in the influence on serum VEGF levels and the therapeutic outcome.
    Korean Journal of Ophthalmology 02/2014; 28(1):32-8.
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    Yong Joon Kim, Sang Hyouk Park, Kyung Seek Choi
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    ABSTRACT: Purpose: To report the ocular health of a community after an accidental release of hydrofluoric acid (HF). Methods: The hospital records of 327 patients that were exposed to HF between Sep 9, 2012 and Oct 31, 2012 were reviewed. Demographic characteristics, subjective ocular symptoms, and the ophthalmologic examination results of the patients were analyzed retrospectively. Results: Among the 327 patients, 203 patients (62.1%) were exposed to hydrofluoric acid (HF) within 1,000 m of the site of the accident. A total of 131 patients (40.1%) were exposed to HF over 3 days. The most frequently reported ocular symptoms after HF exposure were ocular pain (49.5%) and conjunctival hyperemia (37.9%). Conjunctival hyperemia (43.4%), corneal erosion (23.9%), conjunctiva papilla, and follicles (24.2% and 14.4%, respectively) were noted during ophthalmologic examinations, but 46.2% of patients were normal on examination. None of the patients had vision-threatening damages. Conclusions: In this study, severe ocular surface changes, which can affect vision, were not identified. This result could be explained by the low atmospheric HF concentration after the accident.
    Journal of the Korean Ophthalmological Society 11/2013; 54(11):1663-8.
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    ABSTRACT: To evaluate the clinical usefulness of binocular multifocal electroretinography (mfERG) by comparing results with conventional monocular mfERG in patients with monocular macular disease. mfERG testing was conducted on 32 patients with monocular macular disease and 30 normal subjects. An initial mfERG was simultaneously recorded from both eyes with two recording electrodes under binocular stimulation. A second mfERG was subsequently recorded with conventional monocular stimulation. Amplitudes and implicit times of each ring response of the binocular and monocular recordings were compared. Ring ratios of the binocular and monocular recording were also compared. In the macular disease group, there were no statistical differences in amplitude or implicit time for each of the five concentric rings between the monocular and binocular recordings. However, with binocular simulation, the ring ratios (ring 1 / ring 4, ring 1 / ring 5) were significantly reduced in the affected eye. In the normal control group, there were no statistical differences in any parameters between the monocular and binocular recordings. Binocular mfERG could be a good alternative to the conventional monocular test. In addition, given that the test needs stable fixation of the affected eye during the binocular test, the reliability of the test results could be improved, especially for patients with monocular macular disease.
    Korean Journal of Ophthalmology 08/2013; 27(4):261-7.
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    ABSTRACT: Purpose: To ascertain the difference of intraocular pressure (IOP) measurement between vitrectomized air-filled and fluid-filled eyes. Methods: Thirty-one eyes of 31 consecutive patients who underwent conventional vitrectomy and intraocular gas tamponade were assessed. After vitrectomy, IOP of the fluid-filled eyes was measured by Tono-Pen. Thereafter, fluid-air exchange was performed, and IOP of the air-filled eyes was measured again. The IOP within each fluid- and air-filled eye was varied by selecting settings on the vitrectomy system, from 10 to 50 mmHg with 5-mmHg increments. Postoperatively, IOP was assessed by both Tono-Pen and Goldmann applanation tonometry (GAT). Linear and nonlinear regression analyses were conducted between intraoperatively measured Tono-Pen readings and actual IOPs. Bland-Altman plot was used to assess the agreements between postoperatively measured Tono-Pen readings and GAT readings. Results: The discrepancy between Tono-Pen readings and actual IOP in fluid-filled eyes was not significant, except for the profound high pressures over 45 mmHg. However, Tono-Pen readings in air-filled eyes were significantly lower than actual IOPs in all ranges, and Tono-Pen increasingly underestimates IOP at higher levels. Intraoperative Tono-Pen readings were correlated significantly with actual IOP and a quadratic equation evidenced the best fit (R(2 ) =( ) 0.996). Postoperatively, difference of the measurements between Tono-Pen and GAT was not significant. Conclusion: Tono-Pen and GAT significantly underestimate actual IOP in air-filled eyes. It should be considered that actual IOP would be greater than the measured IOP in gas-filled eyes, even though the IOP is measured as normal.
    Acta ophthalmologica 05/2013; · 2.44 Impact Factor
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    ABSTRACT: PURPOSE:: The authors investigated the surgical outcomes of massive subretinal hemorrhage draining via a retinotomy procedure in bullous hemorrhagic retinal detachment (HRD). METHODS:: Clinical records of consecutive patients with age-related macular degeneration who underwent surgery for bullous HRD were reviewed. Outcomes included anatomical success, visual acuity, and postoperative complications. RESULTS:: Seventeen consecutive eyes of 17 patients were included in this series. Of the 17 eyes, 8 eyes had total HRD and 9 eyes had half total inferior HRD including the macula. The mean interval between initial symptom presentation and operation was 22.6 ± 11.7 days. All patients underwent pars plana vitrectomy and internal drainage of the subretinal hemorrhage through a posterior drainage retinotomy. The mean follow-up period was 37.1 months (range, 12-66 months). Finally, successful retinal reattachment was achieved in 15 of the 17 eyes (88.2%), but 2 remained nonprogressive localized inferior retinal detachment because of proliferative vitreoretinopathy. All preoperative visual acuities were hand movements or worse, and 10 eyes (58.8%) achieved a postoperative minimum functional vision of 20/1000 or better. CONCLUSION:: Successful retinal reattachment and achievement of minimum functional vision is possible after PPV and retinotomy with evacuation of a massive subretinal hemorrhage for bullous HRD secondary to age-related macular degeneration.
    Retina (Philadelphia, Pa.) 03/2013; · 2.93 Impact Factor
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    Yong Joon Kim, Kyung Seek Choi
    Plastic and Reconstructive Surgery 02/2013; 131(2):298e-9e. · 3.33 Impact Factor
  • Hae Jung Sun, Kyung Seek Choi, Sung Jin Lee
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    ABSTRACT: Intravitreal injection of bevacizumab in retinopathy of prematurity has shown satisfactory results without any systemic complications. However, increased fibrosis and tissue contraction are reported as adverse effects in some cases. A premature girl, born at 29 weeks + 4 days of gestation, had bilateral aggressive posterior retinopathy of prematurity (APROP) on her first screening at 3 weeks of age. She received extensive, near confluent, laser ablation of the avascular retina and off-label intravitreal bevacizumab (0.75 mg) injection OU. The right eye showed a slight regression, but a localized tractional membrane was noted OS. After another intravitreal bevacizumab injection in each eye, the left eye underwent lens-sparing vitrectomy (LSV) because of contraction of the proliferative membrane leading to a dome-shaped tractional retinal detachment (TRD). At 6-week follow-up, the left eye showed complete retinal reattachment. Both eyes showed prompt resolution of vascular engorgement with anterior progression of the peripheral retinal vasculature. Intravitreal bevacizumab is safe and effective as a treatment of APROP. In some cases tissue contraction may occur, but because TRD is localized to the posterior pole, effective LSV can be performed.
    Japanese Journal of Ophthalmology 07/2012; 56(5):476-80. · 1.80 Impact Factor
  • Seung Hoon Kim, Kyung Seek Choi
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    ABSTRACT: To compare the infusion pressure shown by a vitrectomy device with the actual intraocular pressure (IOP) observed during pars plana vitrectomy. Furthermore, we evaluated the effects of variable parameters on the actual IOP during vitrectomy surgery. Porcine eyes were obtained within 24 h of slaughter. Actual IOP was measured by a digital manometer during vitrectomy using the vented gas forced infusion (VGFI) system, as well as the gravity system. We analyzed the actual IOP according to the groups divided by remnant volume of infusion fluid: (500 ml; control group, 250, 125, and 50 ml). Finally, actual IOP was determined after changing variable parameters such as cutting rate, vacuum pressure, and the VGFI setting. Settings for a VGFI system and pressure supplied by a gravity system significantly correlated with actual IOP (r = 0.99, p = 0.0001; r = 0.99, and p = 0.0001). Actual IOP declined with decreasing volume of infusion fluid. If the volume of infusion fluid was <125 ml, actual IOP decreased significantly compared with the control group and the difference in actual IOP reflected a significant difference in the VGFI setting of 30 mmHg. Cutting rate as well as VGFI setting and vacuum pressure affected actual IOP. Infusion pressure shown by the vitrectomy device was similar to actual IOP in porcine eyes. However, volume of infusion fluid and variable parameters could change the actual IOP during pars plana vitrectomy. Our results may help to optimize the ideal parameters such as infusion pressure, vacuum pressure, and cutting rate of vitrectomy systems used to treat vitreoretinal diseases.
    Current eye research 05/2012; 37(8):698-703. · 1.51 Impact Factor
  • Sun Young Jang, Kyung Seek Choi, Sung Jin Lee
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    ABSTRACT: Intravitreal injection of bevacizumab has been shown to satisfactorily treat retinopathy of prematurity; nevertheless, the safety of antivascular endothelial growth factor therapy in children remains uncertain. We report a patient with bilateral, zone 1, stage 3 plus retinopathy of prematurity who was treated with combined laser photocoagulation and intravitreal ranibizumab injection and demonstrated full regression at 3 months after injection but then developed bilateral retinal detachments 1 month later.
    Journal of AAPOS: the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus 10/2010; 14(5):457-9. · 1.07 Impact Factor
  • Sun Young Jang, Kyung Seek Choi, Sung Jin Lee
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    ABSTRACT: We describe the surgical technique of using an illuminated infusion chandelier for cataract extraction in patients with absent red reflex due to vitreous hemorrhage. A 23-gauge illuminated infusion chandelier was used for cataract extraction in 6 consecutive patients (6 eyes) who underwent combined surgery: phacoemulsification and 23-gauge sutureless vitrectomy. During surgery, the light from the illuminated infusion chandelier was used to enhance the red reflex and to better visualize the lens structure and capsule. Continuous curvilinear capsulorhexis and phacoemulsification were successfully performed. Capsular polishing was also performed safely and easily. The posterior capsule remained intact and the intraocular lens was inserted into the bag in all cases. Thus, the use of the 23-gauge illuminated infusion chandelier can improve visualization of the lens structure and capsule, thereby facilitating successful cataract extraction in select patients with vitreous hemorrhage.
    Archives of ophthalmology 07/2010; 128(7):911-4. · 3.86 Impact Factor
  • Kyung Seek Choi, Hoon Dong Kim, Sung Jin Lee
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    ABSTRACT: To compare the shape and self-sealing nature of scleral incision sites according to bevel shape and trocar blade direction in 23-gauge microincisional vitrectomy surgery. Twenty-three-gauge microincisional vitrectomies were performed in 60 eyes using a single-step entry system (Alcon Surgical, USA) and a 23-gauge two-step Eckardt vitrectomy system (DORC, the Netherlands). Trocar cannula were inserted using trocar blades bevel-up (20 eyes) or bevel-down (20 eyes). In 20 eyes, trocars were inserted after sclerotomies were performed using a microvitreoretinal (MVR) blade. After removing the cannula, we compared the scleral wound shapes and looked for leakage. A total of 180 sclerotomies were done: 60 in the bevel-up direction (group 1), 60 in the bevel-down direction (group 2), and 60 using an MVR blade (group 3). Bevel-up insertion produced a V-shaped sclerotomy wound, whereas bevel-down insertion produced a reverse V-shaped wound. The MVR blade produced a slit-shaped wound. Wound leakage was identified in 21 V-shaped wounds, seven reverse V-shaped wounds, and four slit-shaped wounds. We observed no cases of hypotony, vitreous incarceration, or endophthalmitis. The self-sealing effect of slit-shaped wounds and reverse V-shaped wounds was superior to that of V-shaped wounds.
    Current eye research 06/2010; 35(6):499-504. · 1.51 Impact Factor
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    ABSTRACT: Two patients complained of blurred vision approximately 6 months after having combined vitrectomy and phacoemulsification with implantation of a C-flex 570C hydrophilic acrylic intraocular lens (IOL). Multiple granules were noted on the anterior surface of the IOLs in both patients. Intraocular lens exchange was performed in both eyes, and the explanted IOLs were sent for histopathological analysis. Scanning electron microscopy confirmed the presence of cracks and granules on the IOL surfaces and energy-dispersive x-ray spectroscopy demonstrated calcium deposition. Based on the calcification pattern on the anterior surface of the IOLs, 2 additional cases of opacification were identified under slitlamp examination. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
    Journal of Cataract and Refractive Surgery 04/2010; 36(4):676-81. · 2.75 Impact Factor
  • Kyung Seek Choi, Sung Yong Park, Hae Jung Sun
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    ABSTRACT: Scleral fixation of a foldable intraocular lens (IOL) was performed in 17 eyes of 17 patients using a new small incision technique with injector implantation. All eyes were implanted with a hydrophobic acrylic three-piece IOL, either with phacoemulsification surgery or secondarily. No cases of intraoperative or postoperative complications were observed. The operation time required for scleral fixation only was less than 30 minutes in all cases. Scleral fixation of foldable IOLs using a self-sealing tunnel incision and injector technique minimizes intraoperative hypotony and related complications such as suprachoroidal hemorrhage. Furthermore, this technique saves surgery time and the sutureless technique used for most patients can reduce postoperative astigmatism.
    Ophthalmic Surgery Lasers and Imaging 03/2010; 41(2):272-5. · 1.32 Impact Factor
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    Jun Ho Choi, Sung Jin Lee, Kyung Seek Choi
    Journal of the Korean Ophthalmological Society 01/2010; 51(6).
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    Yong Jun Lee, Kyung Seek Choi, Sung Jin Lee
    Journal of the Korean Ophthalmological Society 01/2010; 51(6).