Peng Cui

Hefei University of Technology, Luchow, Anhui Sheng, China

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Publications (143)317.42 Total impact

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    ABSTRACT: An Ms7.0 earthquake, focal depth 13 km, struck Lushan on April 20, 2013, caused 196 deaths and 21 missing, 13,484 injuries, and affected more than two million people. A field investigation was taken immediately after the quake, and the induced hazards were analyzed in comparison with the Wenchuan earthquake. We have identified 1,460 landslides and avalanches and four dammed lakes, which were generally small and concentrated on high elevation. Avalanches and rockfalls developed in cliffs and steep slopes of hard rocks, including Jinjixia of Baosheng Town and Dayanxia of Shuangshi Town, Lushan, and the K317 section the Xiaoguanzi section north to Lingguan Town along the provincial highway S210. Landslides were relatively less, mainly in moderate and small scales, developing in sandstone, shale, and loose colluviums. Only one single large landslide was observed to turn into debris slide-flow. Dammed lakes were formed by avalanches and landslides, all in small size and of low danger degree. The earthquake-induced hazards distributed in belt on the hanging wall along the faults, and their major controlling factors include tectonics, lithology, structure surface, and landform. More than 99 % landslides were within 30 km to the epicenter, and 678 within 10 km, accounting for 46 % of the total; about 50 % landslides were distributed on slopes between 35° and 55°, and 11 % on slope exceeding 75°; 60 % on slopes at the altitudes between 1,000 and 1,500 m, 77 % on slopes between 900 and 1,500 m; and 24 and 62 % in hard rocks and section between hard and soft rocks, respectively. Compared with the case of Wenchuan earthquake, both the number and extension of landslides and avalanches in Lushan earthquake-affected area are much smaller, only 5.53 % in number and 0.57 % in area. The earthquake has increased the instability of slope and potentiality of landslide and debris flow. Accordingly, the active period is expected to be relatively short comparing with that in Wenchuan earthquake-hit area. However, the insidious and concealed hazards bring difficulty for risk investigation.
    Natural Hazards 09/2014; 73(2). · 1.64 Impact Factor
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    ABSTRACT: The formation of landslide dams is often induced by earthquakes in mountainous areas. The failure of a landslide dam typically results in catastrophic flash floods or debris flows downstream. Significant attention has been given to the processes and mechanisms involved in the failure of individual landslide dams. However, the processes leading to domino failures of multiple landslide dams remain unclear. In this study, experimental tests were carried out to investigate the domino failure of landslide dams and the consequent enlargement of downstream debris flows. Different blockage conditions were considered, including complete blockage, partial blockage and erodible bed (no blockage). The mean velocity of the flow front was estimated by videos. Total stress transducers (TSTs) and Laser range finders (LRFs) were employed to measure the total stress and the depth of the flow front, respectively. Under a complete blockage pattern, a portion of the debris flow was trapped in front of each retained landslide dam before the latter collapsed completely. This was accompanied by a dramatic decrease in the mean velocity of the flow front. Conversely, under both partial blockage and erodible bed conditions, the mean velocity of the flow front increased gradually downward along the sloping channel. Domino failures of the landslide dams were triggered when a series of dams (complete blockage and partial blockage) were distributed along the flume. However, not all of these domino failures led to enlarged debris flows. The modes of dam failures have significant impacts on the enlargement of debris flows. Therefore, further research is necessary to understand the mechanisms of domino failures of landslide dams and their effects on the enlargement of debris flows.
    International Journal of Sediment Research 09/2014; 29(3):414–422. · 0.72 Impact Factor
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    ABSTRACT: Melanoma is the most malignant cutaneous cancer and causes over 9,000 deaths annually. Because fatality rates from malignant melanoma (MM) increase dramatically upon metastasis, we investigated tumorigenesis and metastasis of MM in transcriptome analyses of three distinct cell lines that correspond with the stages of MM pathogenesis: the normal stage (HEMn-LP), the onset of MM (A375), and the metastasis stage (A2058). Using next-generation sequencing (NGS) technology, we detected asymmetrical expression of genes among the three cell lines, notably on chromosomes 9, 12, and 14, suggesting their involvement in tumorigenesis and metastasis of MM. These genes were clustered into 41 categories based on their expression patterns, and their biological functions were analyzed using Ingenuity Pathway Analysis. In the top cancer-associated category, HIF1A, IL8, TERT, ONECUT1, and FOXA1 directly interacted with either transcription factors or cytokines that are known to be involved in the tumorigenesis or metastasis of other malignant tumors. The present data suggest that cytokine regulatory pathways in macrophages predominate over other pathways during the pathogenesis of MM. This study provides new targets for the downstream mechanistic studies of the tumorigenesis and metastasis of MM and demonstrates a new strategy for studies of the progression of other malignant cancers.
    Gene 07/2014; · 2.20 Impact Factor
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    ABSTRACT: Translational selection is a ubiquitous and significant mechanism to regulate protein expression in prokaryotes and unicellular eukaryotes. Recent evidence has shown that translational selection is weakly operative in highly expressed genes in human and other vertebrates. However, it remains unclear whether translational selection acts differentially on human genes depending on their expression patterns.
    Biology Direct 07/2014; 9(1):17. · 2.72 Impact Factor
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    ABSTRACT: Cerebrum postnatal development is a complicated biological process precisely controlled by multiple genes. To understand the molecular mechanism of cerebrum development, we compared dynamics of mouse cerebrum transcriptome through three developmental stages using high-throughput RNA-seq technique. Three libraries were generated from mouse cerebrum at infancy, adolescence and adulthood, respectively. Consequently, 44,557,729 (infancy), 59,257,530 (adolescence) and 72,729,636 (adulthood) reads were produced, which were assembled into 15,344, 16,048 and 15,775 genes, respectively. We found that the overall gene expression level increased from infancy to adolescence and decreased later on upon reaching adulthood. The adolescence cerebrum has the most active gene expression, with expression of a large number of regulatory genes up-regulated and some crucial pathways activated. Transcription factors (TFs) analysis suggested the similar dynamics as expression profiling, especially those TFs functioning in neurogenesis differentiation, oligodendrocyte lineage determination and circadian rhythms regulation. Moreover, our data revealed drastic increase of myelin basic protein (MBP)-coding gene expression in adolescence and adulthood, suggesting that brain myelin may be generated since mouse adolescence. In addition, differential gene expression analysis indicated the activation of rhythmic pathway, suggesting the function of rhythmic movement since adolescence; Furthermore, Furthermore, during infancy and adolescence periods, gene expression related to axonrepulsion and attraction showed the opposite trends, indicating that axon repulsion was activated after birth, while axon attraction might be activated at the embryonic stage and declined during the postnatal development. Our results from the present study may shed light on the molecular mechanism underlying the postnatal development of mammalian cerebrum.
    Genomics Proteomics & Bioinformatics 06/2014;
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    ABSTRACT: We present a simple template carbonization method to produce nanoporous carbons in which potassium biphthalate and magnesium powder serve as the carbon source and hard template, respectively. It reveals that increasing the carbonization temperature can lead to an increase in crystallinity but porosity and the resultant electrochemical performance in supercapacitor application also decreases. The carbon-3:1-800 sample that was obtained by carbonizing potassium biphthalate and magnesium powder (mass ratio of 3:1) at 800 °C exhibits the best electrochemical performance. It has the largest BET surface area of 1745.6 m2 g−1 and a high pore volume of 1.46 cm3 g−1. When measured in a three-electrode system, the carbon-3:1-800 sample delivers a large specific capacitance of 234.2 F g−1 at a current density of 1 A g−1 and high capacitance retention of 96.6% even after 10000 cycles. More importantly, the influence of the operation temperature of the carbon-3:1-800 sample on the electrochemical behavior was also investigated in a two-electrode system. The energy density can reach up to 96.9 W h kg−1 in the case of the power density of 1.5 kW kg−1; it also reveals that a higher operation temperature can result in better electrochemical performance, enabling its implementation under extreme circumstances.
    J. Mater. Chem. A. 06/2014; 2(25).
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    ABSTRACT: In areas hit by the 2008 Wenchuan earthquake that occurred in Sichuan Province, China, debris flows are often generated from landslide deposits during heavy rainstorms. The broadly graded and unconsolidated landslide deposits respond to rainfall in very complex mechanical and hydraulic manners. An artificial rainfall test was conducted to simulate the rainfall infiltration and surface runoff processes occurring on the landslide deposit slope at the Wenjiagou Gully, China, with heavy rainfall rates (140 mm/h) incorporated. An innovative flume was designed to collect the slope interflow and surface runoff separately. Sensors to monitor the pore water content (PWP) and volumetric water content (VWC) were deployed. The results indicated that there were four stages in the hydrological response of landslide deposits during the artificial rain event: infiltration, a slow increase in interflow (surface runoff begins), a rapid increase in interflow (surface runoff slowly increases) and a steady state. Bed gradient increase will lead to PWP rapidly ascending and regressive failure happening. Concomitant with the observed increases in PWP and VWC, the shear strength of the landslide deposits decreased and led to the occurrence of small-scale shallow failures. Surface runoff, interflow and fine particle migration effects are presented to interpret the process of shallow failure. And although shallow slope failure is the result of interaction with the above three factors induced by rainfall, the key underlying factor is the characteristically loose structure of landslide deposits.
    Engineering Geology 05/2014; · 1.40 Impact Factor
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    ABSTRACT: We demonstrate a rational template carbonization method to produce nitrogen-containing nanoporous carbons at 800 °C, using 1, 10-phenanthroline (or benzimidazole) as carbon/nitrogen source and magnesium citrate as template. The mass ratio of 1, 10-phenanthroline (or benzimidazole) and magnesium citrate has exerted the vital role in the determination of pore structures and the resulting electrochemical performances. It reveals that the carbon-P:Mg-1:1 (obtained by heating 1, 10-phenanthroline and magnesium citrate at 800 °C with the mass ratio of 1:1) and carbon-B:Mg-1:1 (obtained by heating benzimidazole and magnesium citrate at 800 °C with the mass ratio of 1:1) samples both are amorphous, nitrogen-containing, and highly nanoporous in nature. The carbon-P:Mg-1:1 sample has a large BET surface area of 1,657.4 m2 g−1 and high pore volume of 1.83 cm3 g−1, and those of carbon-B:Mg-1:1 sample are of 1,105.4 m2 g−1 and 1.67 cm3 g−1, respectively. Based on a three-electrode system using a 6-mol L−1 KOH aqueous solution as electrolyte, the carbon-P:Mg-1:1 and carbon-B:Mg-1:1 samples can deliver large specific capacitances of 289.0 and 255.6 F g−1 at a current density of 0.5 A g−1. They can also exhibit high energy densities of 40.1 and 35.5 Wh kg−1 when designated the power density as 0.25 kW kg−1 as well as highly long-term cycling durabilities.
    Journal of Solid State Electrochemistry 03/2014; · 2.28 Impact Factor
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    ABSTRACT: Porous carbons have been synthesized by a direct carbonization of potassium biphthalate without an activation process. The experimental results demonstrate that the carbonization temperature plays a crucial role in determining the surface area and pore structure as well as the correlative capacitive performance. The carbon-700/800/900 samples display surface areas of 672, 1,023, and 1,380 m2 g−1 and total pore volumes of 0.38, 0.56, and 0.78 cm3 g−1, respectively. The specific capacitances of the carbon-700/800/900 samples are 300.4, 272.3, and 243.4 F g−1, respectively, at a current density of 0.5 A g−1. More importantly, the carbon-900 sample possesses the highest capacitance retention (~98.4 %) even undergoing charge–discharge 10,000 times. The potassium biphthalate used as a carbon source is inexpensive and commercially available, making it promising for the large-scale production of porous carbons as an excellent electrode material for supercapacitors.
    Journal of Solid State Electrochemistry 01/2014; 18(1). · 2.28 Impact Factor
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    ABSTRACT: Declining vegetation coverage caused by serious soil erosion in dry-hot river valley of the Jinsha River has resulted in a vicious cycle of environmental deterioration and aggravated soil erosion. In order to identify the relationship between vegetation succession and transformation of soil erosion, the methods of “space replacing time” and 137Cs technique have been used to analyze community structure of vegetation and distribution characteristics of 137Cs contents in the slopes and vegetation units of five succession stages, which included native grassland, shrub, sapling forest, half-mature forest and near mature forest in Jiangjiagou gully, Dongchuan city, Yunnan province. We found, during the course of succession, the number of species in communities increased with vegetation development and succession, but the 137Cs loss decreased with vegetation succession. Following the succession, near mature forest had the highest 137Cs inventory and native grassland had the lowest 137Cs inventory in both slopes and vegetation units. Principal component analysis showed that 137Cs inventory was significantly positively correlated with average crown diameter of tree (ACDT), species number, tree coverage and average tree height. Average crown diameter of shrub (ACDS) and average shrub height were also positively related to 137Cs inventory but to a lesser extent. Based on the results of our study, we illustrated the improvement of soil erosion control through soil conservation and water regulation with vegetation succession. Consequently, the results suggest that community features significantly affect soil erosion, through which we can evaluate and predict the soil erosion intensity of different vegetation.
    Ecological Engineering 01/2014; 62:13–26. · 2.96 Impact Factor
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    ABSTRACT: The density, viscosity, and surface tension of aqueous solution of 1,4-bis-(2-hydroxypropyl)-piperazine (HPP) sulfate, corresponding to a molar ratio of HPP to sulfuric acid of 2:1, were measured at different temperatures, up to 333.15 K. The HPP sulfate mass fraction ranged from (0.062 to 0.372). The density and viscosity experimental data have been correlated with different equations. Results showed that the density, viscosity, and surface tension of the aqueous solution of HPP sulfate decreased as the temperature increases. The density and viscosity increased with mass fraction of HPP sulfate, whereas surface tension decreased linearly with temperatures from (303.15 to 333.15) K. The density and viscosity correlated values are in good agreement with the experimental ones. The surface tension of the aqueous solution of HPP sulfate decreased with HPP sulfate mass fraction quickly in HPP sulfate mass range of (0.062 to 0.248); however, when HPP sulfate mass fraction was from (0.248 to 0.372), the decrease rate obviously reduced, suggesting that molecular association in HPP sulfate solution played an important role on surface tension.
    Journal of Chemical & Engineering Data 11/2013; 58(12):3327–3331. · 2.00 Impact Factor
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    ABSTRACT: High-performance porous carbons as supercapacitor electrode materials have been prepared by a simple but efficient template carbonization process, in which commercially available terephthalic acid–zinc complex is used as a carbon source. It reveals that the carbonization temperature plays a crucial role in determining the structure and capacitive performance of carbons. The carbon-1000 sample has high surface area of 1138 m2 g–1 and large pore volume of 1.44 cm3 g–1 as well as rationally hierarchical pore size distribution. In a three-electrode system, the carbon-1000 sample possesses high specific capacitances of 266.0 F g–1 at 0.5 A g–1 and good cycling stability. In a two-electrode system, the operation temperature (25/50/80 °C) can greatly influence the electrochemical performance of the carbon-1000 sample, especially with an extended voltage window ( 3 V). The temperature-dependent operation makes it possible for the application of supercapacitors under extreme conditions.
    Industrial & Engineering Chemistry Research. 11/2013; 52(46):16211–16219.
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    ABSTRACT: To explore the mechanisms controlling erythroid differentiation and development, we analyzed the genome-wide transcription dynamics occurring during the differentiation of human embryonic stem cells (HESCs) into the erythroid lineage and development of embryonic to adult erythropoiesis using high throughput sequencing technology. HESCs and erythroid cells at three developmental stages: ESER (embryonic), FLER (fetal), and PBER (adult) were analyzed. Our findings revealed that the number of expressed genes decreased during differentiation, whereas the total expression intensity increased. At each of the three transitions (HESCs-ESERs, ESERs-FLERs, and FLERs-PBERs), many differentially expressed genes were observed, which were involved in maintaining pluripotency, early erythroid specification, rapid cell growth, and cell-cell adhesion and interaction. We also discovered dynamic networks and their central nodes in each transition. Our study provides a fundamental basis for further investigation of erythroid differentiation and development, and has implications in using ESERs for transfusion product in clinical settings.
    Genomics 10/2013; · 3.01 Impact Factor
  • G.G.D. Zhou, K.H. Hu, P. Cui
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    ABSTRACT: Understanding the characteristics and mechanics of granular avalanches along sloping channels is fundamental and vital for the study of different geophysical flows in the field. By using the discrete element method (DEM), three-dimensional (3D) granular (mass) flows along a sloping channel are numerically modelled to study the contact behaviour between solid particles. The evolution of 3D unsteady granular flows from a quasi-static state to an inertial flow is systematically investigated through numerical simulations. Captured velocity profiles along the flow height show variation in the flow regimes, while utilisation of the definition of the Savage number allows study of the vibration of solids inside a granular body along the sloping channels. These numerical results are compared with field measurements to observe the effect of channel confinement on the solids discharge per unit width of granular flows. This particulate study illustrates that, for unsteady granular flows, solid particles in the front head are more collision dominated, with shear rates and Savage numbers greatly enhanced. Also, the solids discharge inside a granular body is not uniformly distributed. Finally, channel width acts as a confinement to the granular debris flow, which can significantly affect sediment transport.
    Journal of Flood Risk Management 06/2013; 6(2). · 1.49 Impact Factor
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    ABSTRACT: During the last 70 years of general climatic amelioration, 18 glacial-lake outburst floods (GLOFs) and related debris flows have occurred from 15 moraine-dammed lakes in Tibet, China. Catastrophic loss of life and property has occurred because of the following factors: the large volumes of water discharged, the steep gradients of the U-shaped channels, and the amount and texture of the downstream channel bed and bank material. The peak discharge of each GLOF exceeded 1000 m3/s. These flood discharges transformed to non-cohesive debris flows if the channels contained sufficient loose sediment for entrainment (bulking) and if their gradients were >1%. We focus on this key element, transformation, and suggest that it be included in evaluating future GLOF-related risk, the probability of transformation to debris flow and hyperconcentrated flow. The general, sequential evolution of the flows can be described as from proximal GLOFs, to sedimentladen streamflow, to hyperconcentrated flow, to non-cohesive debris flow (viscous or cohesive debris flow only if sufficient fine sediment is present), and then, distally, back to hyperconcentrated flow and sediment-laden streamflow as sediment is progressively deposited. Most of the Tibet examples transformed only to non-cohesive debris flows. The important lesson for future hazard assessment and mitigation planning is that, as a GLOF entrains (bulks) enough sediment to become a debris flow, the flow volume must increase by at least three times (the "bulking factor"). In fact, the transforming flow waves overrun and mix with downstream streamflow, in addition to adding the entrained sediment (and thus enabling addition of yet more sediment and a bulking factor in excess of three times). To effectively reduce the risk of GLOF debris flows, reducing the level of a potentially dangerous lake with a siphon or excavated spillway or installing gabions in combination with a downstream debris dam are the primary approaches.
    Physical Geography. 05/2013; 31(6):508-527.
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  • 01/2013;
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    ABSTRACT: Debris flows are typically caused by natural terrain landslides triggered by intense rainfalls. If an incoming mountain torrent collapses a series of landslide dams, large debris flows can form in a very short period. Moreover, the torrent can amplify the scale of the debris flow in the flow direction. The catastrophic debris flows that occurred in Zhouqu, China, on 8 August 2010 were caused by intense rainfall and the upstream cascading failure of landslide dams along the gullies. In the wake of the incident, a field study was conducted to better understand the process of cascading landslide dam failures and the formation of debris flows. This paper looks at the geomorphic properties of the debris-flow gullies, estimates the peak flow discharges at different locations using three different methods, and analyzes the key modes (i.e., different landslide dam types and their combinations) of cascading landslide dam failures and their effect on the scale amplification of debris flows. The results show that five key modes in Luojiayu gully and two modes in Sanyanyu gully accounted for the scale amplification of downstream debris flows in the Zhouqu event. This study illustrates how the hazardous process of natural debris flows can begin several kilometers upstream as a complex cascade of geomorphic events (failure of landslide dams and erosion of the sloping bed) can scale to become catastrophic discharges. Neglecting recognition of these hazardous geomorphic and hydrodynamic processes may result in a high cost.
    Geomorphology 01/2013; 182:173–189. · 2.58 Impact Factor
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    ABSTRACT: Mammalian testis development is a complex and highly sophisticated process. To study the dynamic change of normal testis development at the transcriptional level, we investigated mouse testes at three postnatal ages: 6 days postnatal, 4 weeks old, and 10 weeks old, representing infant (PN1), juvenile (PN2), and adult (PN3) stages, respectively. Using ultra high-throughput RNA sequencing (RNA-seq) technology, we obtained 211 million reads with a length of 35 bp. We identified 18837 genes that were expressed in mouse testes, and found that genes expressed at the highest level were involved in spermatogenesis. The gene expression pattern in PN1 was distinct from that in PN2 and PN3, which indicates that spermatogenesis has commenced in PN2. We analyzed a large number of genes related to spermatogenesis and somatic development of the testis, which play important roles at different developmental stages. We also found that the MAPK, Hedgehog, and Wnt signaling pathways were significantly involved at different developmental stages. These findings further our understanding of the molecular mechanisms that regulate testis development. Our study also demonstrates significant advantages of RNA-seq technology for studying transcriptome during development.
    Science China. Life sciences 12/2012; · 2.02 Impact Factor
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    ABSTRACT: A debris-flow catastrophe hit the city of Zhouqu, Gansu Province, western China, at midnight on 7 August 2010 following a local extreme rainfall of 77.3 mm h-1 in the Sanyanyu and Luojiayu ravines, which are located to the north of the urban area. Eight buildings damaged in the event were investigated in detail to study the characteristics and patterns of damage to buildings by debris flows. It was found that major structural damage was caused by the frontal impact of proximal debris flows, while non-structural damage was caused by lateral accumulation and abrasion of sediment. The impact had a boundary decreasing effect when debris flows encountered a series of obstacles, and the inter-positioning of buildings produced so-called back shielding effects on the damage. Impact, accumulation, and abrasion were the three main patterns of damage to buildings in this event. The damage scale depended not only on the flow properties, such as density, velocity, and depth, but also on the structural strength of buildings, material, orientation, and geometry. Reinforced concrete-framed structures can effectively resist a much higher debris-flow impact than brick-concrete structures. With respect to the two typical types of structure, a classification scheme to assess building damage is proposed by referring to the Chinese Classification System of Earthquake Damage to Buildings. Furthermore, three damage scales (major structural, minor structural, and non-structural damage) are defined by critical values of impact pressure. Finally, five countermeasures for effectively mitigating the damage are proposed according to the on-site investigation.
    Natural hazards and earth system sciences 07/2012; 12(7):2209-2217. · 1.75 Impact Factor

Publication Stats

3k Citations
317.42 Total Impact Points

Institutions

  • 2006–2014
    • Hefei University of Technology
      • School of Chemical Engineering
      Luchow, Anhui Sheng, China
  • 2004–2014
    • Beijing Genomics Institute
      Bao'an, Guangdong, China
    • Chinese Academy of Sciences
      • • Institute of Mountain Hazards and Environment
      • • Key Laboratory of Zoological Systematics and Evolution
      • • Key Laboratory of Materials Physics
      • • Institute of Solid State Physics
      Peping, Beijing, China
  • 2012
    • King Abdullah University of Science and Technology
      • Computational Bioscience Research Center (CBCR)
      Djidda, Makkah, Saudi Arabia
  • 2005–2012
    • Northeast Institute of Geography and Agroecology
      • • Institute of Mountain Hazards and Environment
      • • Institute of Solid State Physics
      • • Key Laboratory of Materials Physics
      Peping, Beijing, China
  • 2001–2010
    • Hefei Institute of Physical Sciences, Chinese Academy of Sciences
      Luchow, Anhui Sheng, China
  • 2008
    • Sichuan University
      Hua-yang, Sichuan, China
  • 2007
    • Inner Mongolia Agricultural University
      Suiyüan, Inner Mongolia, China
  • 1995
    • Academia Sinica
      T’ai-pei, Taipei, Taiwan