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ABSTRACT: We report a method of the placement of the guiding catheter in two cases in which the diagnostic catheter could be easily engaged to the target coronary arteries but not a guiding catheter, due to a distorted aortic sinus and an osteal subtotal occlusion, respectively. After engaging to the target coronary artery with a diagnostic catheter, a coronary guidewire was advanced through the diagnostic catheter, and exchanged with a guiding catheter over the guidewires. The procedures were completed with success.
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 11/2012; 40(7):628-31.
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ABSTRACT: We present a 20-year-old male patient with cor triatriatum sinistrum with fenestrations and long-standing dyspnea on exertion, fatigue, and palpitation. An apical early to mid-systolic murmur of grade I-II/VI was heard on cardiac auscultation. Electrocardiography showed sinus rhythm and an incomplete right bundle branch block. Transthoracic echocardiography showed a membrane dividing the left atrium into two compartments. Transesophageal echocardiography showed a membrane with fenestrations originating from the left upper pulmonary vein, extending to the interatrial septum, and dividing the left atrium into two compartments as proximal and distal. Cardiac MR imaging for further detailed anatomical assessment demonstrated similar findings without additional anomaly. Medical follow-up was conducted due to no pressure gradient across the membrane.
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 06/2012; 40(4):347-9.
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Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 04/2012; 40(3):286.
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 06/2011; 11(4):373; author reply 373-4. · 0.44 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 05/2011; 11(3):277; author reply 277-8. · 0.44 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 02/2011; 11(1):E3-4. · 0.44 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 11/2010; 10(6):559; author reply 559. · 0.44 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 11/2010; 10(6):E29. · 0.44 Impact Factor
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ABSTRACT: QT prolongation and obesity are associated with ventricular arrhythmia and sudden cardiac death. The relationship between uncomplicated obesity and QT interval prolongation is not clear.
The aim of the study was to investigate the effects of uncomplicated obesity on QT interval in young men.
A total of 122 men, including 59 obese patients and 63 controls, were recruited into the study. Patients with hypertension, diabetes mellitus, and ischemic heart disease were ineligible. Body mass index (BMI) of all patients was calculated. QT interval was measured from the precordial lead--V5, and corrected QT (QTC) was calculated using the Bazett's formula.
Mean age, BMI, and waist circumference (WC) of obese patients and controls were as follows: 22.0 +/-3.0 years, 36.2 +/-2.2 kg/m(2), and 114 +/-8.1 cm; 22.6 +/-2.9 years, 24.7 +/-2.5 kg/m(2), and 81.6 +/-7.5 cm, respectively. There was a statistically significant difference between the obese and control groups with regard to BMI and WC (P <0.001). Furthermore, statistically significant differences were observed between the 2 groups in terms of QTC (407.9 +/-17.1 ms vs. 397.7 +/-14.0 ms, respectively, P <0.001), systolic (126.9 +/-8.2 mmHg vs. 114.2 +/-11.1 mmHg, respectively, P <0.001) and diastolic blood pressure (78.3 +/-4.5 mmHg vs. 66.9 +/-10 mmHg, respectively, P <0.001). There was a positive correlation between QTC interval and both WC (r = 0.357, P <0.001) and BMI (r = 0.424, P <0.001). There was no association between QTC and blood pressure.
Uncomplicated obesity in young men is associated with QT interval prolongation. Weight gain may inversely affect cardiac repolarization in uncomplicated obesity.
Polskie archiwum medycyny wewnȩtrznej 06/2010; 120(6):209-13. · 1.37 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 06/2010; 10(3):291. · 0.44 Impact Factor
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ABSTRACT: The middiastolic flow of mitral L wave may result from pathologies that impair the diastolic function of the heart. Echocardiographic examination of a 48-year-old female patient with a three-year history of partial pericardiectomy showed mild left ventricular hypertrophy, mild mitral regurgitation, and mitral annular calcification. During pulse-Doppler examination, a prominent forward transmitral flow (mitral L wave) was noted. The patient developed supraventricular tachycardia attacks on simultaneous electrocardiographic monitoring, during which the mitral L wave disappeared, but E and A waves sustained. Variations in the velocities of the forward transmitral flow were less than 25% during deep inspiration. Tissue Doppler imaging showed equal velocities (0.06 m/sec) of the E' and A' waves recorded at the lateral mitral annulus.
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 01/2010; 38(7):499-501.
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Omer Yiğiner,
Namık Ozmen,
Fatih Ozçelik,
Tuğrul Inanç, Ejder Kardeşoğlu,
Omer Uz,
Zafer Işılak,
Mustafa Aparcı,
Irfan Sahin,
Erol Arslan,
Bekir Sıtkı Cebeci
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ABSTRACT: Lipid levels of most patients receiving antilipidemic therapy are not under control as proposed by the guidelines. We evaluated adherence to statin therapy and LDL cholesterol goal attainment in type 2 diabetic and secondary prevention patients.
A total of 194 patients (131 men, 63 women; mean age 57 ± 11 years) who had been on statin therapy for at least a year for a target LDL cholesterol level of <100 mg/dl were administered a two-part questionnaire. The first part inquired demographic and clinical characteristics, duration of hyperlipidemia, referral to a dietician, risk factors and, if present, the reasons for drug discontinuation. The second part consisted of 23 questions (total score 30) inquiring the knowledge levels of patients about hypercholesterolemia.
There were 61 primary (31.4%, diabetics) and 133 secondary (68.6%) prevention patients. The mean LDL level was 122.6 ± 28.7 mg/dl. The incidence of attaining target LDL level was only 23.7% (n=46), being lower in diabetics compared to secondary prevention patients (6.6% vs. 31.6, p<0.0001). The mean knowledge score was 18.2 ± 5. When the threshold score was taken as 18 (median), attainment of the target LDL level was significantly higher in patients having a score of ≥ 18 (32%) compared to those with a lower score (14.9%). There were 77 patients (40%) who sought dietician counseling. Patients with a high school or higher education and those with dietician counseling had higher knowledge scores compared to those with a lower education level and without dietician counseling (p<0.0001). Intermittent drug discontinuation was seen in 109 patients (56.2%), the most common reason being decrease in cholesterol levels to normal (35%).
Target LDL level was achieved in only about 24%. As the knowledge on hypercholesterolemia accrues, the success rate of LDL cholesterol goal attainment increases.
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 01/2010; 38(8):544-50.
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ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) may be associated with insulin resistance. We aimed to evaluate elastic properties of aorta in patients with NAFLD.
Ninety-two patients with NAFLD and 47 healthy subjects were performed ultrasonographic and echocardiographic examination. Aortic stiffness index (ASI), aortic distensibility (AD) and aortic strain (AS) were compared between healthy subjects and patients and also among grade I and II liver steatosis. Statistical analysis was performed by Independent-Samples t-test, Pearson's correlation test using SPSS 11.0.
ASI was significantly increased whereas AS and AD were reduced (p>0.05) in patients compared to normal ones. ASI was significantly increased while AD and AS slightly increased in patients with grade II liver steatosis compare to grade I. SBP and DBP, cholesterol levels, fasting blood glucose (FBG) were also increased and doppler flow parameters of mitral inflow were abnormally changed in those patients. ASI was positively correlated with FBG, ALT and ALP levels, LDL cholesterol, heart rate and deceleration time of mitral E wave.
Elastic properties of aorta were abnormally changed in patients with NAFLD. Multiple hemodynamic abnormalities probably associated with insulin resistance may be accountable for abnormal elastic properties of aorta.
Diabetes research and clinical practice 11/2009; 87(1):44-50. · 2.16 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 09/2009; 9(4):357-8. · 0.44 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 07/2009; 9(3):256. · 0.44 Impact Factor
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Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 01/2009; 37(6):439-40.
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ABSTRACT: We investigated whether coronary calcification detected by multislice computed tomography (MSCT) was correlated with plasma osteopontin, serum fetuin-A, and visfatin levels.
The study included 64 consecutive patients (51 males, 13 females; mean age 49.5+/-10.9 years; range 33 to 78 years) who underwent MSCT for suspected coronary artery disease. Coronary artery calcification (CAC) scores of the patients were calculated using the Agatston scoring method. Plasma osteopontin, serum fetuin-A, and visfatin levels were measured from fasting blood samples and correlations were sought with calcium scores.
Coronary calcification was detected in 32 patients (50%). The mean CAC score was 146.5+/-333.7 Agatston units (AU), indicating an intermediate risk for coronary artery disease. In 10 patients (15.6%), the CAC score exceeded 400 AU. The mean fetuin-A, visfatin, and osteopontin levels were 25.6+/-6.4 ng/ml, 19.7+/-47.2 ng/ml, and 20.4+/-16.1 ng/ml, respectively. Serum visfatin (r=0.15, p=0.37) and fetuin-A (r=0.17, p=0.22) were not correlated with the CAC score, whereas plasma osteopontin level showed a moderate correlation with the CAC score (r=0.35; p=0.008). In ROC analysis, the area under the curve for identification of CAC was greatest for osteopontin (0.741; p=0.004), followed by fetuin-A (0.574; p=0.31), and visfatin (0.580; p=0.27). The cut-off value was 18.45 ng/ml for osteopontin, with a sensitivity of 72% and specificity of 73%.
Our results suggest that there might be an association between CAC and plasma osteopontin levels. Research should continue to find out a metabolic parameter that will strongly indicate coronary calcification.
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 01/2009; 37(6):397-402.
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 10/2007; 7(3):343. · 0.44 Impact Factor
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Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 10/2006; 6(3):286. · 0.44 Impact Factor
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ABSTRACT: Heart failure is a leading cause of cardiovascular mortality and morbidity. It has been shown that inflammatory markers may play a role in the pathogenesis of heart failure. Therefore, inflammatory markers and anticytokine therapy in heart failure have become the attractive subjects in the literature. There are new studies regarding this issue in the literature. In this article, we reviewed inflammatory markers in heart failure and their prognostic significance based on the literature data.
Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology 04/2006; 6(1):51-4. · 0.44 Impact Factor
