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ABSTRACT: Carcinosarcoma of the breast, also known as metaplastic carcinoma, is rare with very few cases reported in the literature. A 46-year old female patient presented with a mass in her left breast. Physical examination, ultrasonography and mammography findings were consistent with malignancy. The mass was totally removed. Histopathological examination revealed carcinosarcoma of the breast. Histologic grade of the tumour was III. Ki67 proliferation index was found 40% positive. Tumour cells were positive for p53 (70% positive), c-erb-B2 (5% positive), pancytokeratin and EMA in carcinomatous areas, and vimentin in sarcomatous areas. There was no metastasis in axillary lymph node and distant metastasis. The patient is receiving chemotherapy and is under follow-up in the 54th month. Along with a review of the literature, we present the information regarding the clinical and histological findings and treatment of the patient who was operated due to breast carcinosarcoma. KEYWORDS: Breast; Carcinoma; Carcinosarcoma.
Journal of Clinical Medicine Research 03/2010; 2(2):96-8.
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Thyroid: official journal of the American Thyroid Association 02/2010; 20(2):231-2. · 2.60 Impact Factor
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ABSTRACT: To compare the efficacy and safety of radical and conservative surgical interventions for liver hydatid disease.
The study comprised 59 patients in two groups who had undergone radical and conservative surgical procedures for liver hydatid disease in our department between 2004 and 2009. Preoperative diagnostic tools, medical treatments, demographic and clinical characteristics, postoperative follow-up, and recurrence were compared in both groups.
This non-randomized retrospective study included 59 patients who had undergone liver hydatid disease surgery. The radical technique was used in 18 patients (mean age: 42.1 +/- 13.5 years, seven male, 11 female), and the conservative technique was used in 41 patients (mean age: 43.5 +/- 13.9 years, 17 male, 24 female). The follow-up period ranged from 3 to 58 mo. Although operative time was significantly shorter in the conservative group (P < 0.001), recurrence was significantly reduced in the radical group (P = 0.045). No statistically significant differences were found in terms of hospitalization duration, cyst count and size, location, postoperative complications, scolicidal solution usage, or follow-up duration between the two groups.
The more effective method for preventing postoperative recurrence is radical surgery. Endoscopic retrograde cholangiopancreatography for bile leakage in the early postoperative period may decrease the requirement for repeat surgery.
World Journal of Gastroenterology 02/2010; 16(8):953-9. · 2.47 Impact Factor
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ABSTRACT: Renal oncocytomas are benign neoplasms derived from cells of the distal renal tubule, and comprise 5% to 7% of primary renal neoplasms. Oncocytomas are mostly asymptomatic, and the majority of tumors are discovered incidentally. In this case report, we present a case of a patient with a giant oncocytoma arising from her left kidney.
We describe a 25-year-old Turkish woman who was admitted to our hospital with abdominal pain and a 3-year palpable abdominal mass, which was found present since her second pregnancy. Examination revealed a 15 x 20-cm mass in her abdominal cavity. Computed tomography revealed a mass with regular outlines, measuring 18 x 11 x 12 cm, associated with the left kidney, and causing marked hydroureteronephrosis. We excised the mass and performed a left nephrectomy on our patient. The immunohistopathology of the mass was consistent with renal oncocytoma. No local or distant metastasis was seen at 6 months postoperatively.
To the best of our knowledge, this is the second largest renal oncocytoma described in the English language literature. This is also the first reported giant oncocytoma that presented during pregnancy.
Journal of Medical Case Reports 01/2010; 4:52.
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ABSTRACT: Vesical diverticula frequently result from bladder outlet obstructions. However, giant vesical diverticula which cause acute abdomen or intestinal obstruction are very rare. Our review of the English medical literature found 3 cases of bladder diverticula which caused gastrointestinal symptoms. Here, we present a 57-year-old man with a giant diverticulum of the urinary bladder who complained of abdominal pain, nausea and vomiting, constipation, no passage of gas or feces, and abdominal distension for 3 d. A 20 cm x 15 cm diverticulum was observed upon laparotomy. The colonic obstruction was secondary to external compression of the rectum against the sacrum by a distended vesical diverticulum. We performed a diverticulectomy and primary closure. Twelve months postoperatively, the patient had no difficulty with voiding or defecation.
World Journal of Gastroenterology 09/2009; 15(31):3957-9. · 2.47 Impact Factor
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ABSTRACT: Foreign body ingestion is rare in adults. In recent years, however, ingestion of the pins that are used for securing turbans has frequently been observed among young Islamic women. This article reviews the patients who were admitted to our emergency unit for turban pin ingestion.
Between 2005 and 2009, 42 patients were admitted to our emergency unit with problems involving turban pins. The patients' characteristics were analyzed, including age; marital status; career; type, number, and location of pins; and history of gastrointestinal surgery.
The patients ranged in age between 11 and 48 years. Of the patients, 22 were single, and 20 were married; 19 were students, and 23 were housewives. The patients visited the emergency unit within 1 to 12 h after they had ingested the pins. Eight of the patients had ingested two pins each, while the others had ingested one pin each. The pins ingested most frequently were those with ball heads. Spontaneous excretion took 3 to 16 days. Of the patients who did not pass the pins spontaneously with feces, the pins were extracted at endoscopy in three and at laparotomy in one. The patients were followed up for 4 to 49 months. No pathological problems were noted during follow-up.
Turban pin ingestion is common in Islamic populations, and the treatment requires a systemic approach and careful follow-up. Pin ingestion can be prevented by increasing public awareness and avoiding holding pins in the mouth when fixing a turban or wearing a type of turban that does not require pins.
Journal of Gastrointestinal Surgery 09/2009; 13(10):1859-63. · 2.83 Impact Factor
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ABSTRACT: An ileal perforation resulting from a migrated biliary stent is a rare complication of endoscopic stent placement for benign or malignant biliary tract disease. We describe the case of a 59-year-old woman with a history of abdominal surgery in which a migrated biliary stent resulted in an ileal perforation. Patients with comorbid abdominal pathologies, including colonic diverticuli, parastomal hernia, or abdominal hernia, may be at increased risk of perforation from migrated stents.
World Journal of Gastroenterology 07/2009; 15(21):2672-4. · 2.47 Impact Factor
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ABSTRACT: Hydatid disease (HD) is a parasitic disease that is most commonly caused by the larval stage of Echinococcus granulosus. It is still a severe public health problem in the world and most commonly involves the liver and the lungs. However, HD can occur in almost any part of the body. Isolated omental hydatid cyst is one of the least common sites. Information about the appearance of cysts within the omentum is limited because of their extremely rare occurrence. In the evaluation of HD, clinical findings, serologic tests, and imaging methods such as plain radiography and ultrasonography are useful. This report describes the clinical, radiologic, and pathologic findings of omental hydatid cyst in addition to a literature review.
Journal of Pediatric Surgery 06/2009; 44(5):1041-3. · 1.45 Impact Factor
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ABSTRACT: Gastrointestinal stromal tumors (GISTs) of the rectum are rare, and their clinical manifestations are variable. We report the case of a 23-year-old woman who was referred complaining of dyspareunia during coitus. We performed digital vaginal and rectal investigations, ultrasound, colonoscopy, and computed tomography. These examinations confirmed the presence of a lesion measuring about 6 × 5 × 5 cm in size attached to the posterolateral left rectum wall. We performed a circumanal excision, then arrived at the mass between the muscles of the pelvic floor. Pathological studies indicated that the tumor was a high-grade GIST, and was clear at the surgical margins. On follow-up, a GIST was found at the gastric fundus via an endoscopic biopsy. Imatinib treatment was initiated because the patient refused a second operation. The gastric lesion disappeared 6 months after imatinib treatment. Dyspareunia disappeared 1 month after operation.
Archives of Gynecology 05/2009; 281(1):153-5. · 0.91 Impact Factor
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ABSTRACT: Cloacogenic carcinoma (CC, basaloid carcinoma) generally occurs around the dentate line, rarely it can arise from the other sides of the colon. There are only 5 cases of CC located outside the anal canal in the literature. The first occurrence of a CC presents as intraabdominal abscess. We describe a 23-year-old male patient who was admitted with fever and severe abdominal pain. Computed tomography imaging showed diffuse wall thickening about 10-11 cm above the rectosigmoid junction, intraabdominal abscess and a soft tissue lession covering the pelvis with a size of 8 × 8.5 cm including cystic necrotic areas. We performed Hartman procedure since the mass was nonresectable. Histopathological examination showed CC. In total, three times radiotherapy and a concurrent three-drug regimen of irinotecan, fluorouracil and folinic acid chemotherapy were administered for 6 weeks. As a result, the patient was lost because of multiple organ dysfunction syndrome that developed 3 months after radio-chemotherapy.
Case Reports in Gastroenterology 01/2009; 3(2):248-254.
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ABSTRACT: Peripancreatic tuberculosis involving the lymph node is rarely seen. In this paper, a case is presented and the literature reviewed. A 28-year-old woman was admitted to the hospital because of pain in the epigastric region, weakness and malaise. Ultrasound and computed tomography scan revealed a mass near the head of the pancreas. The patient was explored for diagnosis. A peripancreatic mass was found adherent to the pancreatic capsule and the frozen section of the mass was reported as lymphadenopathy. The mass was resected totally. Histopathologically, the diagnosis was peripancreatic tuberculous lymphadenitis. She was prescribed antituberculous drugs for one year.
The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology 07/2006; 17(2):137-9. · 0.47 Impact Factor
