Milica Pavlović

University of Belgrade, Belgrade, SE, Serbia

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Publications (13)15.14 Total impact

  • Article: Chemical composition and antimicrobial activity of Anthriscus nemorosa root essential oil.
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    ABSTRACT: The essential oil obtained by hydrodistillation from the roots of Anthriscus nemorosa (Bieb.) Sprengel (Umbelliferae) was analyzed by GC and GC-MS. Among sixty-two compounds identified (representing 89.0% of the total oil), the main components were: n-nonane (12.1%), n-hexadecanol (6.9%), delta-cadinene (6.4%), beta-pinene (6.0%) and germacrene D (5.4%). Furthermore, the antimicrobial activity of the oil was evaluated against the Gram-positive bacteria Staphylococcus epidermidis (ATCC 12228) and Bacillus subtilis (ATCC 6633), the Gram-negative bacterium Escherichia coli (ATCC 25922), and a yeast Candida albicans (ATCC 10259 and ATCC 24433) using the broth microdilution method.
    Natural product communications 02/2011; 6(2):271-3. · 1.24 Impact Factor
  • Article: Comparative analysis of essential oils of six Anthemis taxa from Serbia and Montenegro.
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    ABSTRACT: The essential-oil composition of six Anthemis taxa from several populations in Serbia and Montenegro, Anthemis triumfetti (L.) DC., A. tinctoria L., A. austriaca Jacq., A. ruthenica Bieb., A. cotula L., and A. cretica ssp. carpatica (Willd.) Grierson were analyzed by GC and GC/MS. The main constituents have been identified as follows: camphor (13.8-15.4%), alpha-pinene (5.2-9.3%), beta-pinene (4.9-7.8%), and (E)-caryophyllene (7.3-9.8%) in three populations, and cis-chrysanthenol (27.0%) and 1,8-cineole (8.4%) in one population of A. triumfetti; 1,8-cineole (9.0-25.8%) in the oils of five populations, and borneol (16.0%) and spatulenol (16.0%) in the oil of one population of A. tinctoria; cis-chrysanthenyl acetate (17.5-22.0%), beta-pinene (8.6-13.2%), and 1,8-cineole (7.2-10.4%) in the oils of A. austriaca; germacrene D (8.3-11.3%) and terpinen-4-ol (6.3-7.3%) in A. ruthenica oils; beta-cedrene (10.3-19.0%), (E)-beta-farnesene (7.8-13.5%), and germacrene D (5.2-9.1%) in the oils of A. cotula; cis-thujone (39.0%), trans-thujone (13.5%), and yomogi alcohol (7.1%) in the oil of A. cretica ssp. carpatica. The essential oil of A. austriaca was studied for the first time. A cluster analysis based on the relative percentages of all components of the essential oils was used to determine the distances between taxa and populations.
    Chemistry & Biodiversity 05/2010; 7(5):1231-44. · 1.80 Impact Factor
  • Article: Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity.
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    ABSTRACT: The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Gram (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.
    Natural product communications 02/2010; 5(2):307-10. · 1.24 Impact Factor
  • Article: Composition and antimicrobial activity of Marrubium incanum Desr. (Lamiaceae) essential oil.
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    ABSTRACT: The essential oil from the aerial parts of Marrubium incanum Desr. (Lamiaceae), obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-six compounds were identified, representing 96.3% of the total oil. The main components of the oil were (E)-caryophyllene (27.0%), germacrene D (26.2%) and bicyclogermacrene (11.5%). The microbial growth inhibitory properties of the isolated essential oil were determined using the agar diffusion and broth microdilution method against seven bacterial species (Staphylococcus aureus ATCC 25923, S. epidermidis ATCC 12228, Micrococcus flavus ATCC 10240, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Klebsiella pneumoniae NCIMB 9111, and Pseudomonas aeruginosa ATCC 27853), and two strains of the yeast Candida albicans (ATCC 10259 and ATCC24433). The essential oil showed activity against all the microorganisms tested, but differences in microbial susceptibility were registered.
    Natural product communications 04/2009; 4(3):431-4. · 1.24 Impact Factor
  • Article: Antimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspecies
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    ABSTRACT: The methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbás) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbás & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO·), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed.
    03/2009; 47(4):314-319.
  • Article: Chemical composition and antimicrobial activity of the essential oil from Chaerophyllum aureum L. (Apiaceae).
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    ABSTRACT: The essential oils of the aerial parts and fruits of Chaerophyllum aureum L., collected from two mountains in Serbia, were analyzed by GC and GC/MS. Sabinene (18.5-31.6%), p-cymene (7.9-25.4%) and limonene (1.9-10.9%) were characterized as the main constituents. The oils were tested against six bacterial strains and one strain of yeast, Candida albicans. The highest antimicrobial activity was observed against the Gram-positive bacteria Staphylococcus aureus, S. epidermidis and Micrococcus luteus, while of the Gram-negative strains, Escherichia coli was the most sensitive.
    Natural product communications 02/2009; 4(1):115-8. · 1.24 Impact Factor
  • Article: Composition and Antimicrobial Activity of Salvia amplexicaulis Lam. Essential Oil
    Journal of Essential Oil Research 01/2009; 21(6):563-566. · 0.41 Impact Factor
  • Article: Composition and Antimicrobial Activity of the Rhizome Essential Oils of Two Athamanta turbith Subspecies
    Journal of Essential Oil Research 01/2009; 21(3):276-279. · 0.41 Impact Factor
  • Article: Antioxidant activity of Filipendula hexapetala flowers.
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    ABSTRACT: The antioxidant activity of the methanol extract of Filipendula hexapetala flowers was assessed by the assay for ferric-reducing antioxidant power (FRAP), the assay for DPPH free radical scavenging ability (DPPH) and the assay for the influence of lipid peroxidation in liposomes, induced by Fe(2+)/ascorbate system and measured by the TBA test (LP). The activity of the investigated extract in all test-systems was found to be significant. The principal constituent responsible for the observed effects was isolated and identified as spiraeoside.
    Fitoterapia 05/2007; 78(3):265-7. · 1.85 Impact Factor
  • Article: Essential oil composition of the flowerheads of Chrysanthemum coronarium L. from Greece
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    ABSTRACT: The essential oils of the flowerheads (capitula) of Chrysanthemum coronarium (Compositae), collected in two different locations in Greece, were obtained by hydrodistillation and analysed by GC–MS. Fifty-six constituents were identified, of which oxygenated monoterpenes made the highest contribution. The major constituents in sample A were trans-chrysanthenyl acetate (13.2%), trans-chrysanthenyl isovalerate (10.2%) and cis-chrysanthenyl acetate (9.9%), while those of sample B were camphor (15.7%), cis-chrysanthenyl acetate (9.1%) and trans-chrysanthenyl acetate (7.8%). Copyright © 2007 John Wiley & Sons, Ltd.
    Flavour and Fragrance Journal 02/2007; 22(3):197 - 200. · 1.42 Impact Factor
  • Article: Essential oil composition of Sanicula europaea L.
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    ABSTRACT: The chemical composition of essential oils obtained by hydrodistillation from leaves of Sanicula europaea L. originating from two different localities in Serbia and Montenegro was analyzed using GC and GC-MS. The oils were characterized by a high content of sesquiterpene hydrocarbons (59.5–63.8%). The major compounds were found to be β-selinene (40.4–44.2%), caryophyllene oxide (17.9–19.2%) and α-selinene (3.7–4.0%). Copyright © 2006 John Wiley & Sons, Ltd.
    Flavour and Fragrance Journal 03/2006; 21(4):687 - 689. · 1.42 Impact Factor
  • Article: Composition of essential oil of Stachys alpina L. ssp. dinarica Murb.
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    ABSTRACT: Essential oils of aerial parts of Stachys alpina ssp. dinarica collected from two localities in Bosnia and Herzegovina (Mt Jahorina and Mt Maglic, respectively) were investigated. Essential oils were obtained by hydrodistilation and analyzed using GC and GC-MS. Essential oil yields were 0.03 and 0.05% (w/w), respectively, and in each oil 71 components were identified, comprising 87.2 and 89.3% of the total amount. The main components in both samples were (E)-caryophyllene (13.4 and 9.3%), germacrene D (12.3 and 5.5%), caryophyllene oxide (5.7 and 8.4%), (E)-nerolidol (4.8 and 5.6%), n-nonanal (5.3 and 5.0%) and linalool (1.7 and 5.7%, respectively). Copyright © 2006 John Wiley & Sons, Ltd.
    Flavour and Fragrance Journal 01/2006; 21(3):539 - 542. · 1.42 Impact Factor
  • Article: Essential oil composition of Anthemis triumfetti (L.) DC.
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    ABSTRACT: The essential oil of the aerial parts of Anthemis triumfetti (Asteraceae), obtained by hydrodistillation, was analysed by GC and GC–MS; 64 compounds were identified, representing 98.3% of the oil. The major constituents were β-pinene (16.9%), camphor (15.0%), α-pinene (14.4%) and 1,8-cineole (5.8%). Copyright © 2005 John Wiley & Sons, Ltd.
    Flavour and Fragrance Journal 11/2005; 21(2):297 - 299. · 1.42 Impact Factor