Laure Gobin

University of Liège, Luik, Wallonia, Belgium

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Publications (31)67.62 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: To analyze the behavior of a new double-C-loop quadripod symmetrical intraocular lens (IOL) platform combined with a hydrophilic lens material and a new hydrophobic glistening-free acrylic lens material, Ankoris and Podeye, respectively, in silico (computer simulation), in vitro (laboratory investigation), and in vivo (rabbit model). John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA, and Physiol S.A., Liege, Belgium. Experimental study. An in silico simulation investigation was performed using finite elements software, an in vitro investigation according to the International Organization for Standardization (ISO11979-3:2012), and an in vivo implantation in a rabbit model with 4 weeks of follow-up. Postmortem data were collected by Miyake-Apple gross examination and histopathologic analyses. Biocompatibility and IOL centration were tested. Both IOLs demonstrated statistically insignificant variations in posterior and anterior capsule opacification and Soemmerring ring formation. They were well biotolerated with no signs of toxicity, inflammation, or neovascularization. Axial and centration stability were noted in vitro and in vivo as a result of significant contact between surrounding tissues and haptics and the posterior portion of the optic. The results suggest suitability of the double-C loop IOL platform for the manufacturing of premium (ie, multifocal, toric, and multifocal toric) IOLs. Drs. Bozukova, Gobin, and Pagnoulle are employees of Physiol S.A., Liege, Belgium. Dr. Pagnoulle has a proprietary interest in the tested intraocular lenses. No other author has a financial or proprietary interest in any material or method mentioned. Copyright © 2015 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
    Journal of Cataract and Refractive Surgery 07/2015; 41(7):1490-502. DOI:10.1016/j.jcrs.2014.10.042 · 2.72 Impact Factor
  • C. Chassain · C. Pagnoulle · L. Gobin · J. Rozema ·
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    ABSTRACT: Purpose To assess the rotational stability and centration of a single-piece hydrophilic acrylic intraocular lens (IOL) during the first postoperative year. Setting Clinique Beausoleil, 117, avenue de Lodève, 34070 Montpellier, France. Design Retrospective case series. Method The POD AY 26% monofocal aspheric yellow intraocular lens is designed to facilitate its intraoperative orientation within the capsular bag. This study consists of a retrospective analysis of 117 consecutive eyes implanted with this IOL to determine its postoperative stability. Data collected include ocular biometry, patient history, IOL power, pre- and postoperative visual acuity and refraction, and slit lamp photos after one and three weeks, and 3 and 12 months. Results Mean postoperative visual acuity was 0.95 after 3 months and remained stable after 1 year. The refraction was also stable over time, although a slight effect related to corneal healing could be observed (0.1 D). The mean absolute rotation of the implant was 2.5 ± 2.6°. The position of the center of the implant relative to the pupillary center expressed as a vector was 0.01 mm at 70°. Conclusion This new IOL design is as stable as a C-Loop IOL but provides much better maneuverability during implantation. It provides physiologic centration and good rotational stability over 1 year. It would be a perfect platform for a toric optic.
    Journal francais d'ophtalmologie 04/2013; 36(4):336–342. DOI:10.1016/j.jfo.2012.04.012 · 0.39 Impact Factor
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    ABSTRACT: To determine the hydrophobic, antiglistening, and bioadhesiveness properties of a new polymer, GF raw material, and to determine the suitability of this material for use in intraocular lenses (IOLs). University of Liege, Liege, Belgium. Experimental study. Intraocular lenses made of the new hydrophobic acrylic material were tested and compared with reference acrylic materials. The stability of their polymer matrix was estimated by testing for glistenings. The relative surface hydrophobicity was quantified via contact-angle measurements. The degrees of bioadhesiveness of the reference and test materials were assessed by in vitro porcine lens epithelial cell (LEC) culture. The glistening test showed that the new material had greater stability under worst-case conditions than previous-generation hydrophobic acrylic materials. The new polymer had the same hydrophobic properties as the hydrophobic Acrysof IQ SN60WF material; both materials were less hydrophobic than the hydrophobic Sensar AR40e material and more hydrophobic than the hydrophilic Ioflex IOL material. The in vitro bioadhesiveness tests showed that porcine LEC adhesion levels of the new material were intermediate with respect to those of the 2 reference hydrophobic materials. When equilibrated in aqueous medium, the new-generation hydrophobic acrylic material reached a low water content at equilibrium, making it glistening free. The hydrophobicity and bioadhesiveness of the new raw material were comparable to those of state-of-the-art reference materials; these properties may resist the formation of posterior capsule opacification. Dr. Pagnoulle has a proprietary interest in the GF material. Drs. Pagnoulle, Gobin, and Bozukova are employees of Physiol S.A. Mme. V. Bertrand and Dr. Gillet-De Pauw have no financial or proprietary interest in any material or method mentioned.
    Journal of Cataract and Refractive Surgery 07/2012; 38(7):1271-7. DOI:10.1016/j.jcrs.2012.02.041 · 2.72 Impact Factor

  • Ophthalmology 02/2012; 119(2):212-212. · 6.14 Impact Factor
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    ABSTRACT: To assess the clinical outcomes of bag-in-the-lens intraocular lens (BIL IOL) implantation following the International Organization for Standardization (ISO) 11979-7:2006 in pediatric eyes and eyes with ocular comorbidities. Antwerp University Hospital, Department of Ophthalmology, Antwerp, Belgium. Cohort study. This cohort included the first series of patients having IOL implantation using the bag-in-the-lens technique. Surgeries were performed between December 1999 and September 2006. In addition to IOL implantation, the technique comprised creation of a primary posterior continuous curvilinear capsulorhexis (PCCC) equal in size to the anterior capsulorhexis. The study enrolled 807 eyes of 547 patients; 326 of the eyes (40.40%) had ocular comorbidity. In the 481 eyes without ocular comorbidity, the mean decimal corrected distance visual acuity was 0.52 ± 0.24 (SD) (0.276 ± 0.206 logMAR) preoperatively and 0.94 ± 0.18 (-0.012 ± 0.053 logMAR) postoperatively. The mean postoperative achieved spherical equivalent was 0.48 ± 0.83 diopter (D) and the mean targeted refraction, -0.24 ± 0.71 D. The A-constant was modified from 118.4 to 118.04. Posterior capsule opacification (PCO) did not occur in any adult eye during the follow-up. Retinal detachment after IOL implantation occurred in 10 eyes (1.24%). In 19 eyes, the iris was captured by the IOL haptics postoperatively. Hypopyon occurred in 3 patients and toxic anterior segment syndrome in 1 patient. The BIL IOL met the ISO criteria; that is, primary PCCC was safe in healthy eyes and in eyes with ocular comorbidities and no eye developed PCO over a mean follow-up of 26.1 ± 21.3 months.
    Journal of Cataract and Refractive Surgery 12/2011; 37(12):2120-9. DOI:10.1016/j.jcrs.2011.06.025 · 2.72 Impact Factor
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    ABSTRACT: To theoretically and experimentally assess a new aspheric diffractive trifocal intraocular lens (IOL). Centre Spatial de Liège, Liège, Belgium. Evaluation of diagnostic test or technology. The theoretical profile of the IOL was designed using software simulation and validated by optical calculation software tools that enabled complete theoretical characterization. These data resulted in a new aspheric diffractive trifocal IOL. The IOL theoretically allows improved intermediate vision without impairing near and far vision and favors distance vision in mesopic conditions without increasing halos or glare perception under dim light or large pupil conditions. The theoretical findings were compared with those of in vitro testing on the optical bench. There was good agreement between the theoretical profile and achieved IOL profile. The simulated and achieved light distribution and focus distribution showed good concordance. The FineVision aspheric trifocal IOL provided intermediate addition at 1.75 diopters. The combination of 2 diffractive profiles to achieve far, intermediate, and near correction is validated. Further clinical investigations are required to validate these principles. Dr. Houbrechts has no financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.
    Journal of Cataract and Refractive Surgery 11/2011; 37(11):2060-7. DOI:10.1016/j.jcrs.2011.05.047 · 2.72 Impact Factor

  • Ophthalmology 11/2011; 118(11):2309-2309.e1; author reply 2309-10. DOI:10.1016/j.ophtha.2011.06.027 · 6.14 Impact Factor
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    ABSTRACT: To report on the influence of rigid gas permeable contact lens (CL) wear on the results of ultraviolet A/riboflavin cross-linking (CXL) for stabilisation of progressive keratoconus. Prospective non-comparative study of 15 eyes without CL and 12 eyes fitted with CL from 1 to 10 weeks post-CXL. None of the patients had been wearing CL before CXL. The effect of the CXL treatment was measured by the change from the baseline of best spectacle corrected visual acuity (BSCVA), refractive sphere and cylinder, maximal keratometry value (K max), simulated keratometry steep, flat, astigmatism, refractive power (RP) steep, flat and astigmatism, I-S value on EyeSys (EyeSys Vision Inc, Houston, Texas, USA) and K max on Pentacam (Oculus Optikgeräte, Wetzlar, Germany). The results of these measurements are reported pre-CXL and at 6-month intervals up to 18 months post-CXL. Results In the eyes without CL, none of the study parameters showed a significant change from baseline. Only in the group of eyes fitted with CL post-CXL, several parameters showed a significant improvement: I-S value and K max on EyeSys (all time points), RP steep and simulated astigmatism (6 and 12 months) and RP flat (12 months). CL can be a confounding factor in interpreting the results of CXL: lens wear itself leads to improved topographic parameters.
    The British journal of ophthalmology 07/2011; 95(10):1402-5. DOI:10.1136/bjophthalmol-2011-300329 · 2.98 Impact Factor
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    ABSTRACT: To determine surgically induced astigmatism (SIA) after monofocal spherical intraocular lens (IOL) implantation using the bag-in-the-lens (BIL) technique. Department of Ophthalmology, Antwerp University Hospital, Antwerp, Belgium. Case series. Adult patients had routine phacoemulsification followed by BIL IOL implantation, which requires a double capsulorhexis for IOL fixation. The 2.8 mm limbo-corneal self-sealing incision was temporally located. Preoperative and 3-month postoperative keratometries were measured by Scheimpflug imaging (Pentacam). The patients were divided into 2 groups based on corneal astigmatism. Group A0 consisted of eyes with physiological corneal astigmatism less than 1.00 diopter (D). Group A1 consisted of eyes with corneal astigmatism of 1.00 D or higher. Vector analysis of the corneal power was used to determine the SIA. The study comprised 100 eyes (58 patients). There was no difference in SIA between Group A0 and Group A1. The mean preoperative and postoperative keratometries were highly correlated in both groups (A0: r(2) = 0.95; A1: r(2) = 0.83). The correlation between preoperative and postoperative vectorial astigmatism was low in Group A0 (J0: r(2) = 0.24; J45: r(2) = 0.10). The mean postoperative SIA was 0.06 D @ -24 degrees in Group A0 and 0.09 D @ 6 degrees in Group A1, with an uncertainty of ± 1.00 D. After BIL IOL implantation, the SIA was not statistically significant. Based on these findings, the technique can be considered an option for spherocylindrical correction of corneal astigmatism of 1.00 D or more. No author has a financial or proprietary interest in any material or method mentioned. Additional disclosure is found in the footnotes.
    Journal of Cataract and Refractive Surgery 06/2011; 37(6):1015-9. DOI:10.1016/j.jcrs.2010.12.043 · 2.72 Impact Factor
  • Laure Gobin · Marie-José Tassignon · Danny Mathysen ·
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    ABSTRACT: To propose a method of calculating the power of the 1-sided posterior chamber toric bag-in-the-lens (BIL) intraocular lens (IOL) and propose a misalignment nomogram to calculate the postoperative rotational misalignment or predict the effect of preoperative existing irregular corneal astigmatism. Antwerp University Hospital, Department of Ophthalmology, Antwerp, Belgium. Cohort study. The new IOL calculation formula uses the steepest corneal meridian and flattest corneal meridian separately (regular spherical IOL formula) followed by a customized A-constant approach based on the changes in the IOL principal plane depending on the spherical and cylindrical powers (thickness) of the IOL. The calculation of the remaining astigmatism (power and axis) in cases of postoperative rotational misalignment resulted in a nomogram that can also be used to predict the degree of tolerance for irregular corneal astigmatism correction at the lenticular plane. The calculation is performed using a worksheet. Because 10 degrees of misalignment would result in 35% refractive inaccuracy, it is the maximum acceptable corneal astigmatic irregularity for correction at the lenticular plane. Calculation of spherocylindrical power is specific to each toric IOL. Because the surgeon must fully understand the optical properties of the toric IOL that is going to be implanted, a comprehensive outline of a new calculation method specific to the toric BIL IOL is proposed. Primary rotational misalignment of the toric BIL IOL can be fine tuned postoperatively. Drs. Gobin and Mathysen have no financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.
    Journal of Cataract and Refractive Surgery 06/2011; 37(6):1020-30. DOI:10.1016/j.jcrs.2010.12.057 · 2.72 Impact Factor
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    ABSTRACT: To evaluate the clinical results after implantation of a spherotoric intraocular lens (IOL) using the bag-in-the-lens (BIL) technique. Antwerp University Hospital, Department of Ophthalmology, Antwerp, Belgium. Evidence-based manuscript. Consecutive eyes with cataract and corneal astigmatism had implantation of a spherotoric BIL intraocular lens (IOL). The IOL was centered based on the patient's pupillary entrance using Purkinje reflexes of the surgical microscope light. The study enrolled 52 eyes of 35 patients (23 women) with corneal astigmatism ranging from 0.90 to 6.19 diopters (D). The toric power was between 1.00 D and 8.00 D. One-third of eyes had an additional ocular comorbidity (including amblyopia) that could influence the clinical outcomes; 5.2% had an irregular astigmatism up to 15 degrees. Twelve eyes had high myopia (axial length [AL] >26 mm) and 5 eyes, high hyperopia (AL <21 mm). The mean preoperative corrected distance visual acuity was 0.58 ± 0.25 (SD). Postoperatively, the uncorrected distance visual acuity (UDVA) was 0.5 or better in 92% of eyes, the mean UDVA was 0.85 ± 0.21 D, the mean magnitude of error was 0.05 ± 0.49 D, and the mean angle of error was 0.29 ± 0.89 degree. Astigmatism correction was successful in 82% of eyes. Spherotoric BIL IOL implantation yielded outcomes similar to those with other spherotoric IOLs, even in eyes with ocular comorbidity or irregular astigmatism up to 15 degrees.
    Journal of Cataract and Refractive Surgery 05/2011; 37(5):830-4. DOI:10.1016/j.jcrs.2010.12.042 · 2.72 Impact Factor
  • Marie-José Tassignon · Laure Gobin ·
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    ABSTRACT: More complex optics of intraocular lenses (IOLs) are implanted nowadays, with the aim to correct the ocular sphere and cylinder simultaneously. Alignment of the IOL is a new area of interest for the ophthalmologist. It is well-known that optimal lens alignment will result in optimal quality of the image as perceived by the patient. The bag-in-the-lens implantation is the first IOL that allows surgeon-controlled alignment. Besides its ability to eradicate posterior capsule opacification, its rotation stability was found to be extremely reliable. This new IOL concept was thus considered suitable for going toric. Patients with a cylinder correction, at the lenticular plane, ranging from 2.5 to 6.5 D (mean: 4 D), were selected. The results are very positive, and thus it can be concluded that this new concept of intraocular lens implantation shows a second major advantage, which is the correction of corneal astigmatism at the lenticular plane of medium high to very high dioptrical cylinder powers.
    Expert Review of Ophthalmology 03/2010; 5(2):135-141. DOI:10.1586/eop.10.15
  • Carina Koppen · Laure Gobin · Marie-José Tassignon ·
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    ABSTRACT: With respect to the safety of ultraviolet-A (UVA) crosslinking for the corneal endothelium, an absorption coefficient is used that has been calculated in riboflavin soaked porcine corneas. We aim to validate this value for clinical use by measuring the absorption coefficient for UVA 365 nm in postmortem human corneas after instilling riboflavin on the corneal surface. Corneal thickness was measured in nine pairs of human donor eyes of which one eye was subjected to manual removal of the epithelium, whereas the epithelium of the fellow eye was left intact. Both eyes were instilled with riboflavin 0.1% in dextran 20% on the intact globe. After 20 min, the corneas were rinsed, and a corneoscleral button was trephined. The transmission of the cornea for UVA 365 nm was measured by transillumination, which allows calculation of the absorption coefficient. Measurement of average corneal thickness was 658.5 +/- 51.5 microm when the epithelium was removed, and 758.3 +/- 98.8 microm without epithelial removal. The average transmittance for UVA 365 nm was 12.89 +/- 4.10% with epithelial debridement and 28.52 +/- 4.39% without (P<0.05). The resultant average absorption coefficient is 32 +/- 5 cm when the epithelium is removed and 17 +/- 2 cm when it is left intact (P<0.05). Our results show an absorption coefficient for human corneas that is much lower than the values reported in the literature. This finding may be relevant when considering endothelial safety of the clinical crosslinking treatment.
    Eye & contact lens 03/2010; 36(2):77-80. DOI:10.1097/ICL.0b013e3181d0b74b · 1.47 Impact Factor
  • M-J Tassignon · L Gobin · I De Veuster · D Godts ·
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    ABSTRACT: Evaluate the advantages of the bag-in-the-lens intraocular lens in children undergoing cataract surgery. This prospective study included 54 eyes of 37 children and babies (age, 2 months to 14 years), consecutively operated on between December 1999 and January 2008 for unilateral or bilateral cataract using the "bag-in-the-lens" intraocular lens. Slit-lamp examination, intraocular pressure, visual acuity, and refraction were followed to the best possible degree over time. The mean age of the 37 children at the last consultation visit was 8.3+/-4.9 years. The mean visual acuity improved from 0.2+/-0.1 to 0.8+/-0.3. On the other hand, visual acuity improvement in children presenting hyperplastic persistence of the vitreous was less favorable with a postoperative average visual acuity of 0.14+/-0.18. The mean postoperative refraction in 13 children (26 eyes) operated on for bilateral cataract was 0.5+/-1.5 D for eyes showing axial lengths with substantial variation. The refraction was stable over time in children over 2 years of age. Once the implant was positioned correctly, the remaining epithelial cells of the lens did not migrate toward the visual axis, which was the case in 93.8% of all eyes and in 100% of children over 1 year of age. The "bag-in-the-lens" implant is particularly indicated in children in whom posterior rhexis and optic capture have been recommended since 1994. The implantation minimizes the use of anterior vitrectomy in pediatric cataract surgery, limiting it to those eyes presenting a proliferative hyperplastic vitreous.
    Journal francais d'ophtalmologie 09/2009; 32(7):481-7. DOI:10.1016/j.jfo.2009.06.007 · 0.39 Impact Factor
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    ABSTRACT: To estimate the rotation stability of the bag-in-the-lens (BIL) intraocular lens (IOL) (Morcher 89A) over time and to assess whether the rotational stability of the IOL design is suitable for toric corrections. Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium. This prospective study evaluated patients who had cataract surgery and BIL IOL implantation. Postoperative red reflex photographs were taken 1 day, 5 weeks, and 6 months after surgery. Intraocular lens rotation was obtained by defining a triangle between a scleral blood vessel, the IOL haptic, and the IOL optic center. Changes in the triangle during the follow-up were evaluated using purpose-designed software written in MatLab. Fifty-nine eyes of 49 patients (mean age 68.0 years +/- 11.9 [SD]) were included. There was little postoperative IOL rotation (mean 0.05 +/- 2.02 degrees) between 1 day and 5 weeks (n = 46 eyes) and between 5 weeks and 6 months (mean 0.36 +/- 1.39 degrees) (n = 15 eyes). The IOL rotation remained unchanged from 1 to 6 months postoperatively (P = .327, analysis of variance). There was no correlation between IOL rotation and patient age (r(2) = 0.011) or IOL power (r(2) = 0.003). Postoperative IOL rotations were not different between left eyes and right eyes (P = .862, t test). The BIL IOL showed good rotation stability, making it suitable for toric correction.
    Journal of Cataract and Refractive Surgery 09/2009; 35(8):1385-8. DOI:10.1016/j.jcrs.2009.03.037 · 2.72 Impact Factor
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    ABSTRACT: To report four cases of severe keratitis after standard corneal collagen cross-linking (CXL) treatment for keratoconus. Four patients with progressive keratoconus from two different centers were treated by ultraviolet A (UVA) CXL, using riboflavin as a photosensitizer. The epithelium was removed over the central 8 to 9 mm of the cornea. Riboflavin 0.1% in dextran 20% was instilled every 2 minutes for 30 minutes before UVA exposure. The UV-X light source (IROC), calibrated at 3 mW/cm(2), was applied for 30 minutes while instillation was continued every 2 minutes. At the end of the treatment, a bandage contact lens was applied and topical treatment consisting of a combination of antibiotics and/or anti-inflammatory drops was initiated. Patients experienced delayed (after more than 24 hours) symptoms and signs of inflammation. The eyes showed pronounced ciliary redness with cells in the anterior chamber and central keratic precipitates; multiple white infiltrates had developed at the edge and within the area of CXL. High-dose topical or subconjunctival corticosteroids led to rapid initial improvement of symptoms and signs. Herpes virus could not be detected on the ocular surface or on the anterior chamber tap of one patient. We report four cases of keratitis and corneal scarring from a total of 117 eyes treated with CXL. The location of the scarring determined the amount of loss of visual acuity: in two eyes, there was a persistent decrease in best spectacle-corrected visual acuity.
    Journal of refractive surgery (Thorofare, N.J.: 1995) 09/2009; 25(9):S819-23. DOI:10.3928/1081597X-20090813-11 · 3.47 Impact Factor
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    ABSTRACT: We analyzed an enucleated eye obtained postmortem from an 86-year-old donor who had been implanted with a hydrophilic acrylic bag-in-the-lens 4 months earlier. To our knowledge, this is the first donor eye implanted with this design to undergo pathological analysis. High-frequency ultrasound showed a well-centered IOL, fixated at the level of the capsular bag. Gross and light microscopic analyses of the eye showed that if anterior and posterior capsule openings are well stretched around the optic of this IOL design, proliferative/regenerative material is potentially confined to the intercapsular space of the capsular bag remnant outside the optic rim.
    Journal of Cataract and Refractive Surgery 01/2009; 34(12):2163-5. DOI:10.1016/j.jcrs.2008.06.044 · 2.72 Impact Factor
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    Laure Gobin · Jos J Rozema · Marie-José Tassignon ·
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    ABSTRACT: To propose a comprehensive classification of anisometropia, a method to calculate the theoretical related aniseikonia (objective aniseikonia) and a purpose-designed eikonometer to measure aniseikonia psychophysically (subjective aniseikonia). University Hospital Antwerp, Department of Ophthalmology, Edegem, Belgium. The occurrence of anisometropia was evaluated in 263 patients scheduled for cataract surgery. Subjective aniseikonia was evaluated in 77 healthy patients. The theoretical model was validated to calculate objective aniseikonia by implementing data from the literature. Ultimately, an aniseikogram was developed and its practical use illustrated by 4 clinical cases of anisometropia. In a population of 263 patients, the total incidence of anisometropia was 7.6%, with a dominance of axial anisometropia. Subjective aniseikonia between 2% and 4% was found in 3.0% to 7.5% of the cases, depending on the refractive error. The correlation coefficient between objective and subjective aniseikonia was good (R(2) = 0.82). Analysis of 4 clinical cases illustrated the calculated preoperative and postoperative aniseikonia in 4 types of anisometropia planned for lens removal. Anisometropia is not a rare condition and should be assessed before cataract surgery. A comprehensive method to calculate the objective aniseikonia and to measure the subjective aniseikonia in anisometropia was proposed. If cataract surgery is considered in anisometropic patients, a postoperative aniseikonia of 4% or more may be induced in the case of emmetropization. A method to calculate the intraocular lens power resulting in an acceptable postoperative aniseikonia, especially in axial anisometropic patients, is also proposed.
    Journal of Cataract and Refractive Surgery 08/2008; 34(8):1353-61. DOI:10.1016/j.jcrs.2008.04.023 · 2.72 Impact Factor
  • M. J. Tassignon · I. De Veuster · D. Godts · L. Gobin ·

    Journal Français d Ophtalmologie 04/2008; 31:68-68. DOI:10.1016/S0181-5512(08)70774-5 · 0.39 Impact Factor
  • L Gobin · R Trau · M J Tassignon ·
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    ABSTRACT: To analyze the performances of the Inpro-Gauss Excimer laser in the treatment of hyperopia and combined hypermetropia-presbyopia. The hypermetropic treatment consisted in making 12 confluent ablation spots of 3.3+/-0.1 mm at 4.5 mm from the corneal apex. The surgical parameters were simulated by a computer model of the corneal profile. The combined hypermetropic-presbyopic treatment was achieved by adding 4 spots of +2 D in the infero-nasal quadrant. Our series included forty eyes of which eleven were treated for hyperopia only and twenty nine were treated both for hyperopia and presbyopia. The uncorrected postoperative visual acuity was equivalent or better than the preoperative corrected visual acuity in 82% of cases. The averaged postoperative spherical equivalent was -0.2+/-0.5 D. Near uncorrected visual acuity was one line better (in decimal notation) for the group treated for both hyperopia and presbyopia than in the single hyperopia group. Surface laser treatment of hyperopia and presbyopia with a gaussian broad beam laser is safe, accurate and reproducible.
    Bulletin de la Société belge d'ophtalmologie 02/2008;