Magnus Dencker

Lund University, Lund, Skåne, Sweden

Are you Magnus Dencker?

Claim your profile

Publications (100)255.66 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: There is no general agreement on the spirometric definition of chronic obstructive pulmonary disease (COPD). The global initiative for obstructive lung disease recommends a fixed ratio between forced expiratory volume in one-second (FEV1 ) and forced vital capacity (FVC) of <0·7 (FR) for the diagnosis of COPD. European Respiratory Society and American Thoracic Society favour the use of the fifth percentile of the age-related FEV1 /FVC ratio (the lower limit of normal, LLN). The purpose of this study was to analyse extensive lung function tests in groups of subjects fulfilling none, either or both of the spirometric criteria for COPD. From a previous population-based study, 450 subjects were examined with spirometry, body pletysmography diffusing capacity for CO (DL,CO ), Impulse Oscillometry System (IOS) and answered a questionnaire on respiratory symptoms and diseases. Seventy subjects fulfilled both spirometric COPD criteria (FR+LLN+), 62 subjects the fixed ratio criterion (FR+) only. Of the remaining 318 subjects, 236 were ever smokers (N-ES). Significant differences between all groups were seen for FEV1 and DL,CO . Significant differences between groups were also seen for residual volume (RV) and RV/total lung capacity. For IOS, variables and symptoms increasingly abnormal values were seen from never smokers to FR+LLN+. This study shows that subjects meeting both spirometric COPD criteria frequently have symptoms and findings at extended lung function tests compatible with the diagnosis. Also subjects meeting the fixed ratio criterion only tend to have more symptoms and lung function findings compatible with COPD than ever-smoking subjects with FEV1 /VC > 0·7.
    Clinical Physiology and Functional Imaging 10/2015; DOI:10.1111/cpf.12294 · 1.44 Impact Factor

  • Osteoporosis International 09/2015; DOI:10.1007/s00198-015-3311-y · 4.17 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food intake. Nineteen healthy subjects aged 26·2 ± 4·2 years were investigated. s' was measured with pulsed tissue Doppler imaging in the right and left ventricles before the subjects ate a standardized meal and also 30 and 110 min after the meal. Three measurements were taken in each projection, and a mean value was calculated for each. s' increased significantly (P<0·05) from fasting to 30 min after food intake in every measured site except in the left inferolateral wall (P = 0·15, NS). Several, but not all, variables returned to base value 110 min after food intake. This study shows that food intake affects the tissue Doppler variables used to evaluate systolic heart function. Further studies are needed in older healthy subjects and older subjects with various cardiovascular diseases. © 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.
    Clinical Physiology and Functional Imaging 03/2015; DOI:10.1111/cpf.12242 · 1.44 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: This 11-year prospective longitudinal study examined how a pre-pubertal pediatric bone mass scan predicts peak bone mass. We measured bone mineral content (BMC; g), bone mineral density (BMD; g/cm(2)), and bone area (cm(2)) in femoral neck, total body and lumbar spine by dual-energy X-ray absorptiometry in a population-based cohort including 65 boys and 56 girls. At baseline all participants were pre-pubertal with a mean age of 8 years (range 6-9), they were re-measured at a mean 11 years (range 10-12) later. The participants were then mean 19 years (range 18-19), an age range that corresponds to peak bone mass in femoral neck in our population. We calculated individual BMC, BMD, and bone size Z scores, using all participants at each measurement as reference and evaluated correlations between the two measurements. Individual Z scores were also stratified in quartiles to register movements between quartiles from pre-pubertal age to peak bone mass. The correlation coefficients (r) between pre-pubertal and young adulthood measurements for femoral neck BMC, BMD, and bone area varied between 0.37 and 0.65. The reached BMC value at age 8 years explained 42 % of the variance in the BMC peak value; the corresponding values for BMD were 31 % and bone area 14 %. Among the participants with femoral neck BMD in the lowest childhood quartile, 52 % had left this quartile at peak bone mass. A pediatric bone scan with a femoral neck BMD value in the lowest quartile had a sensitivity of 47 % [95 % confidence interval (CI) 28, 66] and a specificity of 82 % (95 % CI 72, 89) to identify individuals who would remain in the lowest quartile at peak bone mass. The pre-pubertal femoral neck BMD explained only 31 % of the variance in femoral neck peak bone mass. A pre-pubertal BMD scan in a population-based sample has poor ability to predict individuals who are at risk of low peak bone mass.
    Calcified Tissue International 02/2015; 96(5). DOI:10.1007/s00223-015-9965-9 · 3.27 Impact Factor
  • A Malmgren · M Dencker · M Stagmo · P Gudmundsson ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Long--term intensive endurance training leads to increased left ventricular mass and increased left ventricular end--diastolic and left atrial end--systolic diameters. Different types of sports tend to give rise to distinct morphological forms of the athlete's heart. However, the sport--specific aspects have not been fully investigated in female athletes. The purpose of the present study was to investigate differences in left and right cardiac dimensions, cardiac volumes, and systolic and diastolic function in elite female handball players compared to sedentary controls. A cross--sectional study of 33 elite female handball players was compared to 33 matched sedentary controls. Mean age was 21.5 ± 2 years. The subjects underwent echocardiography examinations, both 2--dimensional (2DE) and 3--dimensional (3DE). Cardiac dimensions and volumes were quantified using M--mode, 2DE and 3DE. Systolic and diastolic left ventricular functions were also evaluated. All cardiac dimensions and volumes were adjusted for body surface area (BSA). Left atrium and left ventricle volumes were significantly (p<0.001) larger in elite female handball players compared with sedentary controls. Even right atrium area as well as right ventricular end--diastolic and end--systolic area were significantly (p<0.001) larger in elite female handball players. Significant differences were observed in three out of five systolic parameters. Most diastolic function parameters did not differ between the two groups. The findings from the present study suggest that similar cardiac remodeling takes place in elite female handball players as it does in athletes pursuing endurance or team game sports.
    The Journal of sports medicine and physical fitness 01/2015; 55(4). · 0.97 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Background Intense physical activity (PA) improves muscle strength in children, but it remains uncertain whether moderately intense PA in a population-based cohort of children confers these benefits. Methods We included children aged 6–9 years in four schools where the intervention school increased the school curriculum of PA from 60 minutes/week to 40 minutes/school day while the control schools continued with 60 minutes/week for three years. We measured muscle strength, as isokinetic Peak Torque (PT) (Nm) of the knee flexors in the right leg at speeds of 60°/second and 180°/second, at baseline and at follow-up, in 47 girls and 76 boys in the intervention group and 46 girls and 54 boys in the control group and then calculated annual changes in muscle strength. Data are provided as means with 95% confidence intervals. Results Girls in the intervention group had 1.0 Nm (0.13, 1.9) and boys 1.9 Nm (0.9, 2.9) greater annual gain in knee flexor PT at 60°/second, than girls and boys in the control group. Boys in the intervention group also had 1.5 Nm (0.5, 2.5) greater annual gain in knee flexors PT at 180°/second than boys in the control group. Conclusion A 3-year moderately intense PA intervention program within the school curriculum enhances muscle strength in both girls and boys.
    BMC Musculoskeletal Disorders 10/2014; 15(1):353. DOI:10.1186/1471-2474-15-353 · 1.72 Impact Factor
  • M. Dencker · O. Thorsson · MK Karlsson · P. Wollmer · LB Andersen ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Background and aims Obesity is associated with increased risk of cardiovascular disease (CVD) in adults. We assessed if body fat and abdominal fat are related to clustering of risk factors for CVD in younger children. Methods Cross-sectional study of 170 (92 boys and 78 girls) children aged 8–11 years, recruited from a population-based cohort. Total fat mass (TBF) and abdominal fat (AFM) were measured by DXA. Total body fat was expressed as TBFs percentage of total body mass (BF%). Maximal oxygen uptake (VO2PEAK)was measured by indirect calorimetry. Blood was sampled and blood pressure (BP), and resting heart rate (HR) were measured and pulse pressure (PP) was calculated. Echocardiography was performed and left atrial diameter (LA) was measured, and left ventricular mass (LVM) and relative wall thickness (RWT) were calculated. Z-scores (Value for the individual-mean value for group)/SD) were calculated. Sum of z-scores for triglycerides and lipoprotein concentrations, systolic and diastolic BP, PP, HR, LVM, LA, RWT and -VO2PEAK were calculated in boys and girls, separately, and used as an indices of clustered risk. Results Pearson correlations between ln BF% and ln AFM versus indices of clustered risk were in boys (r = 0.58 and 0.59, p < 0.05), and in girls (r = 0.58 and 0.64, p < 0.05). One-way ANOVA analysis indicated significant differences between different tertiles of BF% and AFM. Higher BF% and AFM were associated with higher clustered risk for CVD in both genders (p < 0.001). Conclusions Both total body fat and abdominal fat were associated with a clustering of CVD risk factors.
    Archives of Disease in Childhood 10/2014; 99(Suppl 2):A94-A95. DOI:10.1136/archdischild-2014-307384.252 · 2.90 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Most pediatric exercise intervention studies, that evaluates the effect on skeletal traits include volunteers and follow bone mass for less than three years. We present a population-based six-year controlled exercise intervention study in children with also bone structure and incident fractures as endpoints. Fractures were registered in 417 girls and 500 boys in the intervention group (3969 person-years) and 835 girls and 869 boys in the control group (8245 person-years), all aged 6-9 years at study start, during the six-year study period. Children in the intervention group had 40 minutes daily school physical education (PE) and the control group 60 minutes per week. In a sub-cohort with 78 girls and 111 boys in the intervention group and 52 girls and 54 boys in the control group, bone mineral density (g/cm(2) ) and bone area (mm(2) ) were measured repeatedly by dual energy X-ray absorptiometry (DXA). Peripheral quantitative computed tomography (pQCT) measured bone mass and bone structure at follow-up. There were 21.7 low and moderate energy related fractures per 1000 person-years in the intervention group and 19.8 fractures in the control group, leading to a Rate Ratio (RR) of 1.12 (0.85, 1.46). Girls in the intervention group, in comparison with girls in the control group, had 0.009 g/cm(2) (0.003, 0.015) larger gain annually in spine BMD, 0.07 g (0.014, 0.123) larger gain in femoral neck BMC and 4.0 mm(2) (0.5, 7.8) larger gain in femoral neck area, and at follow-up 24.1 g (7.6, 40.6) higher tibial cortical BMC (g) and 23.9 mm(2) (5.27, 42.6) larger tibial cross-sectional area. Boys with daily PE had 0.006 g/cm(2) (0.002, 0.010) larger gain annually in spine BMD than control boys but at follow-up no higher pQCT values than boys in the control group. Daily PE for six years in at study start 6-9 year old improves bone mass and bone size in girls and bone mass in boys, without affecting the fracture risk. © 2014 American Society for Bone and Mineral Research.
    Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 06/2014; 29(6). DOI:10.1002/jbmr.2168 · 6.83 Impact Factor
  • Source
    Ylva Gårdinger · Joanna Hlebowicz · Ola Björgell · Magnus Dencker ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Left ventricular wall stress has been investigated in a variety of populations, but the effect of food intake has not been evaluated. We assessed whether left ventricular wall stress is affected by food intake in healthy subjects. Twenty-three healthy subjects aged 25.6 +/- 4.5 years were investigated. Meridional end-systolic wall stress (ESS) and circumferential end-systolic wall stress (cESS) were measured before, 30 minutes after, and 110 minutes after a standardised meal. Both ESS and cESS decreased significantly (P < 0.001) from fasting values 30 minutes after the meal, and had not returned to baseline after 110 minutes. ESS decreased from 65 +/- 16 kdynes/cm2 (fasting) to 44 +/- 12 kdynes/cm2 30 minutes after, and to 58 +/- 13 kdynes/cm2 110 minutes after eating. cESS decreased from 98 +/- 24 kdynes/cm2 to 67 +/- 18 kdynes/cm2 30 minutes after, and to 87 +/- 19 kdynes/cm2 110 minutes after the meal. This study shows that left ventricular wall stress is affected by food intake in healthy subjects.
    Cardiovascular Ultrasound 01/2014; 12(1):2. DOI:10.1186/1476-7120-12-2 · 1.34 Impact Factor
  • Source
    Tina Tanha · Asa Tornberg · Magnus Dencker · Per Wollmer ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Very few validation studies have been performed between different generations of the commonly used Actigraph accelerometers. We compared daily physical activity data generated from the old generation Actigraph model 7164 with the new generation Actigraph GT1M accelerometer in 15 young females for eight consecutive days. We also investigated if different wear time thresholds had any impact on the findings. Minutes per day of moderate and vigorous physical activity (MVPA), vigorous physical activity (VPA) and very vigorous physical activity (VVPA) were calculated. Moreover, minutes of sedentary pursuits per day were calculated. There were significant (P < 0.05) differences between the Actigraph 7164 and the GT1M concerning MVPA (61 +/- 21vs. 56 +/- 23 min/day), VPA (12 +/- 8 vs. 9 +/- 3 min/day) and VVPA (3.2 +/- 3.0 vs. 0.3 +/- 1.1 min/day). The different wear time thresholds had little impact on minutes per day in different intensities. Median minutes of sedentary pursuits per day ranged from 159 to 438 minutes depending on which wear time threshold was used (i.e. 10, 30 or 60 minutes), whereas very small differences were observed between the two different models. Data from the old generation Actigraph 7164 and the new generation Actigraph GT1M accelerometers differ, where the Actigraph GT1M generates lower minutes spent in free living physical activity. Median minutes of sedentary pursuits per day are highly dependent on which wear time threshold that is used, and not by accelerometer model.
    BMC Research Notes 10/2013; 6(1):439. DOI:10.1186/1756-0500-6-439
  • Source
    S Frantz · P Wollmer · M Dencker · G Engström · U Nihlén ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Studies on the influence of alcohol consumption on lung function have shown conflicting results. Self-reported alcohol consumption may be inaccurate. This study used both a validated alcohol questionnaire and a blood marker of heavy alcohol consumption, and examined potential associations with different lung physiological variables. The study population (450 subjects) answered an alcohol questionnaire (AUDIT-C) and performed spirometry, body plethysmography and a test for diffusing capacity for CO (DL,CO). Carbohydrate deficient transferrin (CDT), a clinically used blood marker for identifying heavy alcohol consumption, and C-reactive protein (CRP), a marker of systemic inflammation were analysed. Using AUDIT-C, 407 subjects were alcohol drinkers and 29 non-drinkers. Of the alcohol drinkers, 224 subjects were "hazardous drinkers" and 183 "moderate drinkers". Thirty-four subjects had a CDT ≥2.0% (=heavy drinkers). There was no difference in lung function between hazardous and moderate drinkers. Heavy drinkers had lower DL,CO (74% vs 83% PN, p = 0.003), more symptoms of chronic bronchitis (p = 0.001) and higher AUDIT-C scores (p < 0.001) than non-heavy drinkers. After adjustments (pack years and CRP) the difference in DL,CO (p = 0.037) remained. Multiple regression showed an association between CDT and both FEV1 (p = 0.004) and DL,CO (p = 0.012) in all alcohol drinkers, but not in never-smokers. The AUDIT-C score was associated with CDT (also after adjustments, p < 0.001) but not with any lung function variable. The results from this study suggest that alcohol and particularly heavy drinking has an independent additive negative effect on lung function in smokers.
    Respiratory medicine 09/2013; 108(1). DOI:10.1016/j.rmed.2013.08.041 · 3.09 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Abstract The purpose of this study was to investigate whether Danish children from immigrant backgrounds are less physically active than children from the ethnic majority, and to investigate the possible reasons for any differences found. Accelerometer measures of physical activity as well as questionnaire data about organised sports, family demography, resources and values were collected from 594 children of whom 67 had other ethnic background than Danish. Data were collected when the children were 6-7 years old and again later when the children were 9-10 years old. It was found that children from immigrant backgrounds were not less physically active than other children when their amounts of daily physical activity were measured by direct objective measures, despite their participation rate in organised sports being much lower. Using multiple logistic regression modelling, this study showed that lack of parental experience with organised sports and lack of economic/material resources explained much of the difference in sports participation. Children of immigrant background had significant lower participation in club sports but this did not affect their overall physical activity level.
    05/2013; 13(3):321-31. DOI:10.1080/17461391.2011.635697
  • Source
    Tina Tanha · Asa B Tornberg · Per Wollmer · Magnus Dencker ·
    [Show abstract] [Hide abstract]
    ABSTRACT: We compared, head-to-head, the old generation Actigraph model 7164 with the new generation Actigraph GT1M accelerometer. A total of 15 randomly selected teenagers (eight girls and seven boys) were investigated. They performed a treadmill test wearing the two kinds of accelerometers around the waist simultaneously. The treadmill test consisted of three different levels of speed 4, 6 and 8 km h(-1) for four consecutive minutes. Accelerometer counts per 1 sec epoch for the Actigraph GT1M versus the Actigraph 7164 were at 4 km h(-1) 21·6 ± 12·9 versus 26·5 ± 11·5 counts, at 6 km h(-1) 56·0 ± 23·2 versus 62·9 ± 25·6 counts and at 8 km h(-1) 142·6 ± 37·2 versus 156·4 ± 34·9 counts (P<0·01 for all levels of speed). Data from the old generation Actigraph 7164 and the new generation Actigraph GT1M accelerometers differ, where the Actigraph GT1M generates 10-23% lower values. Correction equation for Actigraph GT1M was Actigraph 7164 = 5·2484 + Actigraph GT1M counts × 1·0448. These results need to be taken into consideration when using these devices.
    Clinical Physiology and Functional Imaging 03/2013; 33(2):162-5. DOI:10.1111/cpf.12003 · 1.44 Impact Factor
  • Source
    M Dencker · P Wollmer · M K Karlsson · L B Andersen · O Thorsson ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Aim: Aerobic capacity, defined as peak oxygen uptake (VO2PEAK), is generally considered to be the best single marker for aerobic fitness. We assessed if VO2PEAK is related to different cardiac dimensions in healthy young children on a population base. Methods: In a cross-sectional study, 245 children (137 boys and 108 girls) aged 8-11 years, were recruited from a population based cohort. VO2PEAK (ml/min-1/kg-1) was assessed by indirect calorimetry during a maximal exercise test. DXA-scan was used to measure lean body mass (LBM) and total fat mass (TBF). Echocardiography, with 2-dimensional guided M-mode, was performed in accordance with current guidelines. Left ventricular end-diastolic diameter (LVDD) and left atrial end-systolic diameter (LA) were measured, and left ventricular mass (LVM) was calculated. Results: Univariate correlations were found between VO2PEAK versus LVDD r=0.44 and LA r=0.27 (both P<0.05) and LVM r=-0.06 (NS) in boys. Corresponding values for girls were; 0.55, 0.34 (both P<0.05) and 0.11 (NS). Multiple regression analysis with VO2PEAK as dependent variable and inclusion of LBM, TBF, sex, age, Tanner stage, and maximal heart rate as independent variables showed that 67% of the total variance of VO2PEAK could be explained by these variables. Including LVDD or LA in the model, added 1% additional explained variance. Conclusion: Findings from this population based cohort of young healthy children show that multiple cardiac dimensions at rest are related to VO2PEAK. However, the different cardiac dimensions contributed very little to the added explained variance of VO2PEAK.
    The Journal of sports medicine and physical fitness 02/2013; 53(1):42-7. · 0.97 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Limited data exist of tracking and changes in accelerometer-measured physical activity in children. Physical activity was assessed by accelerometers for 4 days in 167 children (boys, n = 90; girls n = 77) age 9.8 ± 0.6 years. Follow-up measurement was made 2.0 ± 0.1 yrs later (range 1.9-2.1 yrs). General physical activity (GPA) was defined as mean count/minute. Minutes of inactivity; light, moderate, and vigorous physical activity (LMVPA); moderate and vigorous physical activity (MVPA); and vigorous physical activity (VPA) per day were calculated both as absolute values and as percentage of total registration time. Spearman rank order correlation indicated low tracking of MVPA and VPA in girls (r = .25-0.33, P < .05), and low-moderate tracking of GPA, inactivity, LMVPA, MVPA and VPA in boys (r = .23-0.40, P < .05). Time in inactivity increased at follow-up by 5%-14%. Most of the assessed physical activity variables were decreased at follow-up by 6% to 30%. Physical activity tracks at a low-moderate degree from age 10-12 years, which confirm previous investigations that have used self-report assessments. The low-moderate tracking of physical activity variables indicate that those who were most active initially remained most active. Increasing inactive behavior was observed and that several other physical activity variables were decreased at follow-up.
    Journal of Physical Activity and Health 02/2013; 10(2):241-8. · 1.95 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: We studied the effect in children of an exercise intervention program on fracture rates and skeletal traits. Fractures were registered for 5 years in a population-based prospective controlled exercise intervention study that included children aged 6-9 years at study start, 446 boys and 362 girls in the intervention group and 807 boys and 780 girls in the control group. Intervention subjects received 40 min/school day of physical education and controls, 60 min/week. In 73 boys and 48 girls in the intervention group and 52 boys and 48 girls in the control group, bone mineral density (BMD, g/cm(2)) and bone area (mm(2)) were followed annually by dual-energy X-ray absorptiometry, after which annual changes were calculated. At follow-up we also assessed trabecular and cortical volumetric BMD (g/cm(3)) and bone structure by peripheral computed tomography in the tibia and radius. There were 20.0 fractures/1,000 person-years in the intervention group and 18.5 fractures/1,000 person-years in the control group, resulting in a rate ratio of 1.08 (0.79-1.47) (mean and 95 % CI). The gain in spine BMD was higher in both girls (difference 0.01 g/cm(2), 0.005-0.019) and boys (difference 0.01 g/cm(2), 0.001-0.008) in the intervention group. Intervention girls also had higher gain in femoral neck area (difference 0.04 mm(2), 0.005-0.083) and at follow-up larger tibial bone mineral content (difference 0.18 g, 0.015-0.35), larger tibial cortical area (difference 17 mm(2), 2.4-31.3), and larger radial cross-sectional area (difference 11.0 mm(2), 0.63-21.40). As increased exercise improves bone mass and in girls bone size without affecting fracture risk, society ought to encourage exercise during growth.
    Calcified Tissue International 01/2013; 92(4). DOI:10.1007/s00223-012-9691-5 · 3.27 Impact Factor
  • Tomas Ohrlander · Magnus Dencker · Stefan Acosta ·

    World Journal of Cardiovascular Diseases 01/2013; 03(03):268-274. DOI:10.4236/wjcd.2013.33043 · 0.22 Impact Factor

  • Journal of Science and Medicine in Sport 12/2012; 15:S161. DOI:10.1016/j.jsams.2012.11.394 · 3.19 Impact Factor

  • Journal of Science and Medicine in Sport 12/2012; 15:S161. DOI:10.1016/j.jsams.2012.11.393 · 3.19 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Purpose: Children and adolescents are encouraged to maintain a habitually active lifestyle because of the known health benefits associated with regular physical activity, but there are some reports that a high level of activity may be associated with increased fracture risk. This prospective controlled exercise intervention study in prepubertal children evaluated if a school-based exercise intervention could enhance growth-related gains in muscle strength and muscular function without affecting fracture risk. Methods: Fractures were registered in 417 girls and 500 boys age 7-9 yr in the intervention and in 836 age-matched girls and 872 boys. The intervention included 40 min·d of school physical education for 2 yr, whereas the controls achieved 60 min·wk. In a subsample consisting of 49 girls and 80 boys in the intervention and 50 girls and 53 boys in the control group, body composition was measured by dual-energy x-ray absorptiometry, muscle strength by isokinetic peak torque (PT) of the knee extensors, and flexors at 60 and 180°·s by a computerized dynamometer and neuromuscular performance by vertical jump height. Results: The rate ratio (95% confidence interval) for children in the intervention group to sustain a fracture was 1.07 (0.66-1.68). The annual gain in knee extensor PT at 180°·s was significantly higher for both girls (P < 0.001) and boys (P < 0.01) in the intervention compared with the control group. Boys in the intervention group also had a greater annual gain in knee flexion PT at 180°·s (P < 0.001), and girls had a greater gain in vertical jump height (P < 0.05). Conclusion: An increase in school-based physical education from 60 to 200 min·wk enhanced muscle strength in prepubertal children without affecting fracture risk.
    Medicine and science in sports and exercise 11/2012; 45(5). DOI:10.1249/MSS.0b013e31827c0889 · 3.98 Impact Factor

Publication Stats

1k Citations
255.66 Total Impact Points


  • 2005-2015
    • Lund University
      • • Department of Clinical Sciences, Malmö
      • • Department of Clinical Physiology
      Lund, Skåne, Sweden
  • 2010-2014
    • Skåne University Hospital
      Malmö, Skåne, Sweden
    • University of Southern Denmark
      • Institute of Sports Science and Clinical Biomechanics
      Odense, South Denmark, Denmark
  • 2006-2012
    • Malmö University
      • Department of Cariology
      Malmö, Skåne, Sweden
  • 2011
    • University of Southern Mississippi
      HBG, Mississippi, United States
    • National Sports Medicine Institute
      Лизбург, Virginia, United States