Matthew J. Concannon

University of Missouri, Columbia, Missouri, United States

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Publications (42)107.66 Total impact

  • Steven L Henry, Bradley A Hubbard, Matthew J Concannon
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    ABSTRACT: Postoperative splinting is common after carpal tunnel release, despite a lack of scientific evidence supporting its value. The purpose of this study was to characterize postoperative splinting regimens among hand surgeons and to identify trends in splint use after this procedure. Questionnaires were mailed to members of the American Society for Surgery of the Hand. Recipients were asked to record whether and for how long they use splints after carpal tunnel release. They were also asked to indicate their training (i.e., orthopedic, plastic, or general surgery). Results were compared with those of previously conducted surveys. One thousand ninety-one questionnaires were returned, for a response rate of 48 percent. Fifty-three percent of respondents use splinting postoperatively. Duration of splinting varied tremendously, from 1 to 42 days. Splinting patterns were similar across all training backgrounds. In comparison with related surveys conducted in 1987 and 1997, a trend is evident toward less use of splinting after carpal tunnel release. The use and duration of splinting after carpal tunnel release vary widely among hand surgeons. This divergence of practice implies that there is little therapeutic benefit to splinting after this procedure, a concept supported by substantial scientific evidence and by a trend away from splinting over the past 20 years.
    Plastic and Reconstructive Surgery 11/2008; 122(4):1095-9. DOI:10.1097/PRS.0b013e31818459f4 · 3.33 Impact Factor
  • Steven L. Henry, Matthew J. Concannon
    Plastic &amp Reconstructive Surgery 03/2008; 121(3). DOI:10.1097/01.prs.0000299651.89976.04 · 3.33 Impact Factor
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    Steven L Henry, Matthew J Concannon, Gloria J Yee
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    ABSTRACT: Magnets are purported to aid wound healing despite a paucity of scientific evidence. The purpose of this study was to evaluate the effect of static magnetic fields on cutaneous wound healing in an animal model. The literature was reviewed to explore the historical and scientific basis of magnet therapy and to define its current role in the evidence-based practice of plastic surgery. Standardized wounds were created on the backs of 33 Sprague-Dawley rats, which were divided into 3 groups with either a 23 gauss magnet (group 1), a sham magnet (group 2), or nothing (group 3) positioned over the wound. The rate of wound closure by secondary intention was compared between the groups. Literature review was conducted through searches of PubMed and Ovid databases for articles pertinent to magnets and wound healing. Wounds in the magnet group healed in an average of 15.3 days, significantly faster than those in either the sham group (20.9 days, P = .006) or control group (20.3 days, P < .0001). There was no statistically significant difference between the sham and control groups (P = .45). An externally applied, low-power, static magnetic field increases the rate of secondary healing. Review of the literature reveals conflicting evidence regarding the use of magnetic energy to aid the healing of bone, tendon, and skin. Level I studies are lacking and difficult to execute but are needed to define conclusively the role of magnets in clinical practice.
    Eplasty 02/2008; 8:e40.
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    ABSTRACT: Herbal medicines are used by a considerable number of surgical patients. An increased risk of bleeding, substantiated by anecdotal reports, has been attributed to the use of certain herbs, and numerous in vitro experiments have identified some herbal extracts as platelet inhibitors. The purpose of this investigation was to determine whether standard commercial preparations of commonly used herbal medicines have an effect on platelet function in vivo and, by extension, to provide clinical scientific evidence of the safety of their use in the perioperative period. Five commercially available herbal agents were investigated, including Ginkgo biloba, garlic, Asian ginseng, St. John's wort, and saw palmetto. In a blinded fashion, one of the agents was administered to 10 adult volunteers at the manufacturer's recommended dose for 2 weeks. At the end of the 2-week period, in vivo platelet function was quantified using the PFA-100 assay. After a 2-week "washout" period, the protocol was repeated using a different agent. This 4-week cycle was repeated for each of the five herbal agents, as well as the control agent aspirin. In vivo platelet function was not affected by the administration of any herbal agent and was markedly inhibited with the administration of aspirin. The herbal medicines investigated in this study do not affect platelet function in vivo. Neither this experiment nor a review of the literature supports the concern of perioperative bleeding in users of these herbal medicines.
    Plastic and Reconstructive Surgery 01/2008; 120(7):2044-50. DOI:10.1097/01.prs.0000295972.18570.0b · 3.33 Impact Factor
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    ABSTRACT: Matrix metalloproteinases are enzymes that serve to degrade the extracellular matrix, giving them a central role in the inflammatory and wound-healing processes; they have been implicated in the pathophysiology of hypertrophic scarring. The purpose of this study was to examine the effect of minocycline, a matrix metalloproteinase inhibitor, on hypertrophic scarring. Standardized wounds were created on the ears of eight New Zealand White rabbits. Half of the rabbits received daily injections of minocycline, whereas the other half received daily injections of saline (control). After 4 weeks, the resulting ear scars were harvested. Histologic slides were prepared from the thickest cross-sections of the scars, and from these slides the cross-sectional area of each scar was measured. A hypertrophic index was calculated by comparing the area of the scar to the baseline value of unwounded skin. Statistical analysis was performed using the SAS/STAT NESTED Procedure for hierarchical data. Among the rabbits treated with minocycline, the mean hypertrophic index was 1.08 +/- 0.01, compared with 1.54 +/- 0.03 in the control group (p = 0.03), representing an 85 percent reduction in hypertrophic area. Systemically administered minocycline significantly reduces the severity of hypertrophic scarring in a rabbit model. Although not directly examined in this study, matrix metalloproteinase inhibition is hypothesized to be responsible for this effect.
    Plastic and Reconstructive Surgery 08/2007; 120(1):80-8; discussion 89-90. DOI:10.1097/01.prs.0000263325.73400.f8 · 3.33 Impact Factor
  • Steven L Henry, Matthew J Concannon, Charles L Puckett
    Plastic and Reconstructive Surgery 02/2007; 119(1):442-4. DOI:10.1097/01.prs.0000233620.73320.23 · 3.33 Impact Factor
  • Matthew J Concannon, Steven L Henry
    Plastic and Reconstructive Surgery 11/2005; 116(5):1579-80. DOI:10.1097/ · 3.33 Impact Factor
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    ABSTRACT: Microvascular anastomotic thrombosis is a significant clinical problem, particularly in crush and avulsion injuries. Platelet deposition plays a particularly important role in the initiation and propagation of microvascular thrombosis, whereas thrombin has little effect in the acute phase of thrombus formation. Nevertheless, heparin (a specific thrombin inhibitor) remains the most widely used microvascular irrigant. The purpose of this study was to evaluate tirofiban HCl (Aggrastat), a glycoprotein IIb/IIIa inhibitor, and its role in preventing postoperative thrombosis in a crush anastomosis model. A crush injury model using the rat femoral artery was used. End-to-end microvascular repairs were performed. One milliliter of irrigant was used within the vessel lumen before placement of the last suture. The irrigant used was randomized into one of four groups: lactated Ringer's as a control, tirofiban (50 microg/ml), heparin (100 U/ml), and a combination of heparin (100 U/ml) and tirofiban (50 microg/ml). The vessels were reexamined 24 hours postoperatively and patency was assessed. A total of 62 vessels were used for the study. The patency rate was two of 20 (10 percent) for the control group, 13 of 22 (59 percent) for the tirofiban group, one of 10 (20 percent) for the heparin group, and eight of 10 (80 percent) for the heparin plus tirofiban group. This study demonstrates a statistically significant improvement in patency with tirofiban irrigation in a crush anastomosis rat model when compared with saline or heparin alone. Clinically, tirofiban may have utility as a potent anticoagulant and is potentially useful in microvascular injuries that have a significant crush/avulsion component.
    Plastic and Reconstructive Surgery 08/2005; 116(1):205-8. DOI:10.1097/01.PRS.0000169938.26534.97 · 3.33 Impact Factor
  • Faeza R. Kazmier, Matthew J. Concannon, C Lin Puckett
    Plastic &amp Reconstructive Surgery 01/2005; 116:149-150. DOI:10.1097/00006534-200509011-00124 · 3.33 Impact Factor
  • Benjamin W Beckert, Charles L Puckett, Matthew J Concannon
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    ABSTRACT: Fresh water injuries are often contaminated with bacteria that are not typically encountered in other wounds. Their treatment should include empiric administration of appropriate antibiotics. This study identifies the most common pathogens found in the Lake of the Ozarks and their antibiotic sensitivity. Eleven of the twelve lake water samples (92%) had a positive culture result. Sixty-seven percent of lake water samples contained at least two strains of bacteria. Five different bacterial species of gram negative rods were isolated. All isolates were sensitive to Cefotetan, Ceftazidime, Ceftriaxone, Imipenem, Levofloxacin, Tobramycin, and Trimetheprim/sulfa. Antibiotic coverage after traumatic wounds required gram positive coverage. Our study suggests the addition of gram negative coverage for penetrating trauma contaminated by fresh water.
    Missouri medicine 01/2004; 101(3):219-21.
  • York J Yates, Matthew J Concannon
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    ABSTRACT: There are two types of fungi (yeasts and molds) both of which can cause superficial infections of the perionychium. Yeasts (such as Candida albicans) grow as single cells and reproduce by asexual budding. In contrast, molds grow in long filaments, called hyphae. There are approximately 100,000 species of fungi that have been characterized. Most of these are ubiquitous. Fortunately only about 200 are human pathogens, and only a handful are commonly found to be associated with human disease. This article discusses causes, symptoms, diagnosis, and treatment of the most common fungal infections of the perionychium, including superficial dermatophytosis, onychomycosis, and chronic paronychia.
    Hand Clinics 12/2002; 18(4):631-42, vi; discussion 643-6. DOI:10.1016/S0749-0712(02)00039-2 · 1.07 Impact Factor
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    ABSTRACT: Free fat grafts from liposuction aspirate can be used as donor material for soft-tissue augmentation. The purpose of this study was to attempt to identify a subpopulation of adipose cells within liposuction aspirate with the greatest viability and, it is hoped, a greater chance for increased survival after transplantation. Liposuction samples were obtained from 20 individuals (16 women, four men; age range, 27 to 49 years). These samples were then centrifuged at 50 g. At 2-minute intervals, specimens from three different areas (superficial, middle, deep) were obtained from each specimen. After collagenase degradation, the specimens were stained with trypan blue, and the number of viable cells were counted. The bottom (deepest) layer consistently contained the highest number of viable cells after centrifugation: 250 percent more viable cells when compared with the top layer (p < 0.0001) and 140 percent more viable cells when compared with the middle layer (p < 0.0002). Centrifugation beyond 2 minutes did not increase the number or proportion of viable adipocytes. When using aspirated fat from liposuction for soft-tissue augmentation, centrifugation for 2 minutes at 50 g will stratify the adipocytes, with more viable cells being found at the deepest layer. Using only this bottom portion of the fat layer for transplantation will yield a fat graft with a greater number of viable adipocytes, potentially improving fat graft survival and decreased fat graft resorption.
    Plastic &amp Reconstructive Surgery 02/2002; 109(2):761-5; discussion 766-7. DOI:10.1097/00006534-200202000-00054 · 3.33 Impact Factor
  • Journal of the American College of Surgeons 10/2000; 191(4). DOI:10.1016/S1072-7515(00)00626-8 · 4.45 Impact Factor
  • Matthew J. Concannon, Mona L. Brownfield, Charles L. Puckett
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    ABSTRACT: Endoscopic carpal tunnel release has been used to decompress the median nerve in carpal tunnel syndrome for over the past decade, with an advantage (over the traditional "open" release) being decreased pain in the postoperative period. The goals of this study were to attempt to define the recurrence rate after endoscopic carpal tunnel release and to determine if it differs from that of open technique. The charts of 191 consecutive carpal tunnel syndrome patients treated operatively at the University of Missouri were reviewed. For this study, recurrent carpal tunnel syndrome was defined as documented cases in which the symptoms had resolved following surgical release but subsequently recurred, requiring surgical rerelease of the carpal tunnel. All endoscopic releases were performed using the Chow two-portal technique. Statistical analysis was performed using Fisher's exact test. A total of 103 patient hands had open carpal tunnel releases; 88 were endoscopically released. Total follow-up time (from the initial release) averaged 29 months for the open group and 22 months for the endoscopic group. There were no recurrences in the open group and six recurrences in the endoscopic group (7 percent, p = 0.008). All six recurrences were in worker's compensation patients. The median time between endoscopic release and rerelease was 8.5 months. There seems to be a statistically higher incidence of recurrence of carpal tunnel syndrome after endoscopic release compared with the traditional "open" release in our cases. Although the pathogenesis of this increased rate of recurrence is not clear, this should be considered when planning surgical release of the volar carpal ligament for carpal tunnel syndrome.
    Plastic &amp Reconstructive Surgery 05/2000; 105(5):1662-5. DOI:10.1097/00006534-200004050-00010 · 3.33 Impact Factor
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    Matthew J. Concannon, Gregory M. Bazell, Charles L. Puckett
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    ABSTRACT: An open injury at the distal dorsal finger with loss of the teminal extensor tendon mechanism is challenging to treat, particularly if there is associated overlying soft tissue loss as well. Current options for this type of injury include joint fusion or revision amputation (in severe cases). We present a case of a patient who had a 1.5-cm loss of the terminal extensor tendon with associated loss of the overlying skin that was successfully reconstructed with a palmaris longus tendon graft and covered with a reversed cross-finger flap in the immediate postinjury setting. This technique has allowed restoration of active flexion and extension of the distal interphalangeal joint.
    Operative Techniques in Plastic and Reconstructive Surgery 02/2000; 7(1):16-19. DOI:10.1053/oa.2000.6164
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    ABSTRACT: The use of digital wound images could allow remote consultation among patients, physicians, or other care-givers located at quite distant sites by means of the Internet. To evaluate the efficacy and validity of digital images for the evaluation of wounds, the ability and reliability of surgeons to diagnose and make treatment suggestions using digital images of several types of wounds were compared. Twenty-four wound images on 35-mm slides were selected for use in this study. Each slide image was digitized at 24-bit color with a resolution of 640 pixels horizontal by 425 pixels vertical and stored as a JPEG file. These images were then presented as a slide show on a video monitor, with resolution set at 640 x 480. Six physicians examined the images, first in digital format and later in the original slide form. Each observer assessed each wound and possible treatment options by filling out a questionnaire using a series of yes/no questions. For all observers, there was an 87 percent agreement between digital and slide images (p = 0.004). The agreement between the digital and slide images was measured for each individual observer using a kappa coefficient. The agreement level corresponded to the experience of the observer, with the kappa values ranging from greater than 0.8 (almost perfect agreement) for the attending plastic surgeon to just greater than 0.5 (moderate agreement) for the intern. With this study, the feasibility of distance wound consultation using digital images of a quality consistent with consumer-grade digital photography was demonstrated.
    Plastic &amp Reconstructive Surgery 03/1999; 103(2):483-6. DOI:10.1097/00006534-199902000-00018 · 3.33 Impact Factor
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    ABSTRACT: Tumescent liposuction is currently one of the most commonly performed aesthetic procedures. Despite the variable use of preoperative antibiotics, infection is uncommon. Prior works suggest that the low incidence of infection may be due to lidocaine's antibacterial properties. However, these properties have only been demonstrated using concentrations of lidocaine above 0.8%, significantly higher than those used in tumescent liposuction. The purpose of this study was to determine if the commonly used tumescent fluid containing 0.1% lidocaine, 1:1000,000 epinephrine, and 0.012 mEq sodium bicarbonate possesses antibacterial activity. Using the broth microdilution method, the minimum inhibitory concentrations of Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, and Group A beta-hemolytic Streptococcus were determined after exposure to either lidocaine, epinephrine, bicarbonate, or the combination of all three agents. To determine if there were significant growth differences not detectable by the broth microdilution method, bacterial concentrations were obtained through the use of a spectrophotometer, and significant differences from the controls were calculated by one-way analysis of variance. To determine if prolonged exposure to the tumescent mix would alter bacterial growth, a Killing Time study was also undertaken. The results indicated that the minimum inhibitory concentration of lidocaine was not less than 0.5% for any of the bacteria, whereas the lowest minimum inhibitory concentration of the combined solution was 0.25%. The lowest inhibitory concentration as determined by spectrophotometric analysis for the combined solution was 0.13% (p < 0.01). Analysis of the Killing Time data revealed no inhibition of bacterial growth over time. In conclusion, lidocaine, epinephrine, and bicarbonate do exhibit antibacterial properties at high concentrations. However, the commonly used tumescent mixture containing dilute concentrations of these agents does not significantly inhibit the growth of commonly encountered bacteria.
    Plastic &amp Reconstructive Surgery 02/1999; 103(2):666-70. DOI:10.1097/00006534-199902000-00047 · 3.33 Impact Factor
  • M J Concannon, C L Puckett
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    ABSTRACT: Ear amputation can leave a devastating deformity; the application of microsurgical replantation techniques has allowed very favorable aesthetic outcomes when successful. We report a case of ear replantation in a child in whom a venous repair was not performed; instead medicinal leeches were used to decompress the ear in the immediate postoperative setting. This represents the third reported case of successful ear replantation without microsurgical venous anastomosis. A review of the literature reveals the high incidence of venous congestion requiring external decompression (57 percent) and the very high rate of salvage (80 percent) after replantation. Surgeons attempting ear replantation should be aware of the high rate of ear survival in the situation of no venous outflow (with appropriate decompression techniques) and should not abandon attempts at replantation because of the inability to establish venous outflow microsurgically.
    Plastic &amp Reconstructive Surgery 12/1998; 102(6):2088-93; discussion 2094-6. DOI:10.1097/00006534-199811000-00042 · 3.33 Impact Factor
  • Matthew J. Concannon, Charles L. Puckett
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    ABSTRACT: We describe the use of a "lacing apparatus" across large and complex wounds to accomplish wound closure. This technique utilizes the principles of tissue expansion (exploiting inherent extensibility of the skin, mechanical creep, and biologic creep) but is able to employ them in situations in which traditional tissue expansion (utilizing implantable expanders) is not practical. After preparation, the wounds are laced with large nylon suture, which is tightened on a daily basis, typically allowing closure of even massive wounds within 8 to 10 days. In this report, we describe the technical details of wound preparation, application of the lacing apparatus, and postoperative execution of the expansion leading to final wound closure. This technique is particularly valuable in the upper arm, trunk, and lower extremity but has limited application in the distal forearm and the distal third of the lower extremity.
    Plastic &amp Reconstructive Surgery 09/1998; 102(2):377-84. DOI:10.1097/00006534-199808000-00012 · 3.33 Impact Factor
  • Plastic &amp Reconstructive Surgery 07/1998; 101(7):1981-3. DOI:10.1097/00006534-199806000-00033 · 3.33 Impact Factor

Publication Stats

665 Citations
107.66 Total Impact Points


  • 1991–2008
    • University of Missouri
      • • Department of Surgery
      • • Department of Health Management and Informatics
      • • School of Medicine
      • • Department of Orthopaedic Surgery
      Columbia, Missouri, United States
  • 1992
    • Columbia College Missouri
      Columbia, South Carolina, United States