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ABSTRACT: Twenty four hour blood pressure and ECG monitoring, assessment of sexual function (questionnaires, penile artery Doppler flowmetry) were carried out in male hypertensives treated with atenolol, metoprolol, or bisoprolol. Compared with atenolol and metoprolol bisoprolol was found to be more effective and safe. The use of bisoprolol was associated with no negative changes and even with improvement of some parameters of sexual function. Sildenafil could be used for correction of male sexual dysfunction occurring during treatment with other beta-blockers.
Kardiologiia 02/2002; 42(9):39-42. · 0.20 Impact Factor
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ABSTRACT: 20 patients with complicated urinary infection (CUI) have been treated with levofloxacine (tavanik) for 10 days in a single daily dose 250 mg. They were compared with 23 acute pyelonephritis patients given ciprofloxacin in a dose 1 g/day. None of the patients had purulent inflammation or was treated with antibacterial drugs. The response to tavanik and its safety were good or very good in 95% patients. With ciprofloxacin the same results were achieved in 88% patients. 3 patients failed this treatment. 2 patients developed purulent pyelonephritis and were operated. The number and intensity of side effects were higher were less in the tavanik group. Thus, tavanik, a new antibacterial drug from fluoroquinolone group, is effective and low-toxic in complicated infection of the urinary tracts.
Klinicheskaia meditsina 02/2001; 79(12):35-8.
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ABSTRACT: The efficacy of ciprofloxacin was studied in the treatment of 50 women (the average age of 41.6 years) with acute noncomplicated cystitis. The drug was administered in a dose of 100 mg twice a day for 3 days. The reference group included 15 women with the same disease subjected to the routine therapy with cotrimoxazol in a dose of 8 mg and pipemidic acid in a dose of 100 mg administered twice a day. The positive results evident from the subjective clinical improvement and no veritable bacteriuria were stated in 46 patients (92 per cent). The effect was at the average observed in 36 hours in the ciprofloxacin group while in the reference group it was at the average stated in 81.2 hours from the treatment start.
Antibiotiki i khimioterapii͡a = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoĭ i mikrobiologicheskoĭ promyshlennosti SSSR 02/1997; 42(6):42-4.
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ABSTRACT: Forty-five women with miction disorders underwent ambulatory urodynamic examinations. The patients were divided into two groups. In Group A, including 20 women with signs of irritable bladder, the classical urodynamic examination did not reveal any disorder in bladder function. The ambulatory urodynamic examination revealed detrusor hyperactivity in 3 cases and uretral instability in 5. In Group B, including 25 women, the classical urodynamic examination showed detrusor hyperactivity in 7 and uretral instability in 7 others. The ambulatory urodynamic examination confirmed these disorders for 1 and 3 women respectively. In addition, it revealed vesicosphincter dissynergia in 3 cases. In 7 women with enuresia, the ambulatory examination did not reveal any abnormality. These examinations were well tolerated and appeared to be more sensitive and physiological than the usual examination. This method gave more precise information on infraclinical disorders.
Journal d'urologie 02/1996; 102(1):30-2.
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ABSTRACT: Data on the treatment of 152 women with bilateral injuries to the ureters are presented. Many-year experience gained in the treatment of women with such injuries permitted the authors to single out their main causes and to find the most rational methods of derivation of the urine and develop the treatment policy depending on the type of injury to the ureters, complications of these injuries, and anatomo-functional status of the urinary system. Plastic surgery brought good results in 84.4% of patients.
Akusherstvo i ginekologiia 02/1995;
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ABSTRACT: Ultrasonic examinations of the urethra were carried out in 188 women suffering from dysuria, making use of transducers for transcutaneous and transvaginal scanning. The authors describe in detail the echographic picture of the urethra in health and in various diseases, e.g. urethritis, paraurethral fibrosis, cysts, diverticuli, malignant and benign tumors, etc. The diagnostic value of ultrasonography of the urethra is compared to that of urethrocystoscopy, two-balloon cystourethrography, etc. Ultrasonic scanning was found to be the most informative in paraurethral cysts, tumors, diverticuli, and inflammatory diseases of the urethra. The accuracy of ultrasonic diagnosis as against other diagnostic methods was found to be 82.2%.
Akusherstvo i ginekologiia 02/1993;
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ABSTRACT: The paper outlines the problems in the diagnosis and treatment of associated ++uretero-vesicovaginal fistulas on the basis of a follow-up of 72 patients. The most informative diagnostic methods and effective operative techniques are proposed.
Akusherstvo i ginekologiia 06/1991;
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Akusherstvo i ginekologiia 07/1980;
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Akusherstvo i ginekologiia 03/1972; 48(2):23-6.
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Akusherstvo i ginekologiia 12/1971; 47(11):73-4.
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ABSTRACT: Combined antiandrogen therapy (complete androgen blocking) implies surgical or chemical castration in combination with antiandrogen therapy. Both sources of androgens are thus blocked in patients with locally disseminated prostatic cancer. The purpose of this study was to evaluate the efficiency of bikalutamide (150 mg) monotherapy. The study was carried out in 58 patients with prostatic cancer (stages T3-T4) divided into 2 groups: 1) bikalutamide monotherapy (150 mg daily) and 2) bikalutamide (50 mg daily) + bilateral orchidectomy. All patients were examined before and 3, 6, 12, 18, and 24 months after the beginning of therapy. The efficiency of non-steroid antiandrogen was higher in group 1. The mean level of prostate-specific antigen in this group decreased to 10.6 ng/ml by 24 months, while in group 2 to 25.3 ng/ml. Hence, bicalutamide was effective, safe, and well tolerated in our study, and is therefore recommended as monotherapy for patients with disseminated forms of prostatic cancer.
Urologii͡a (Moscow, Russia: 1999)
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ABSTRACT: 33 patients with benign prostatic hyperplasia (BPH) were exposed to hyperbaric oxygenation (HBO) and SHF waves. Group 1 patients had no prostatic inflammation, group 2 patients had combination of BPH with chronic prostatitis. Both these modalities are considered as to mechanism of action at different periods of the development of urination disturbances. The combined therapy imposed a positive trend in urination parameters, especially evident in group 2 patients. In them mean urination frequency reduced from 14.8-8.5 times to 6.3, mean urine volume increased from 83.6 to 199 ml. Index I-PSS fell in group 1 by 2 and group 2 by 6.4 scores. L index of quality of life declined by 1.2 and 1.6 scores in groups 1 and 2, respectively. It is inferred that combined use of HBO and SHF therapy is highly effective in urination disorders in patients with BPH suffering from or without chronic prostatitis.
Urologii͡a i nefrologii͡a
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Urologii͡a i nefrologii͡a
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ABSTRACT: On the basis of 32 surgical cases of recurrent urorectal fistulas, review of relevant literature, the authors define factors determining choice of treatment and preoperative preparation policy. Such individual approach may secure success in many cases. A new surgical procedure of surgical treatment of urethrorectal fistulas involving abdominoanal resection of the rectum with implantation of the sigmoid into the anus has been tried and found satisfactory.
Urologii͡a i nefrologii͡a
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ABSTRACT: Basing on 139 cases with vesicovaginal fistulas treated, the authors review diagnostic and clinical aspects of these fistulas, the performance of fistuloplasty via transvesical approach. Clear indications for fistuloplasty via transvesical approach have been formulated.
Urologii͡a i nefrologii͡a
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ABSTRACT: To estimate the rate of positive surgical margin (SM) in radical retropubic prostatectomy and its role in emergence of prostatic cancer (PC) recurrence, we operated 216 PC patients aged 41 to 73 years. Most of the patients had clinical stages T2a,b (41.8%) or T3a (35.6%). Stages T1 and T3b were in 18.7 and 3.9% patients, respectively.A positive SM was registered in 68 of 193 patients (35.2%). Thirty six (52.9%) patients had a focal (solitary or short) SM, thirty two (47.1%) had a long SM. The recurrence occurred in 31 (16.1%) patients who, as a rule, had long SM. Recurrence-free one-year survival in 104 patients who had no SM reached 82%, in 34 patients with focal SM (group 2) it was 83%. Such three-year survival in group 1 and 2 was 75 and 73.6%, respectively. Thus, recurrence-free survival in organ-limited process and short SM differed little within 3 years. The period between 12 and 24 months of follow-up is most risky in relation to detection of recurrence in short SM. The group of patients with long SM had maximal number of recurrences.
Urologii͡a (Moscow, Russia: 1999)
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ABSTRACT: Intracavernous injections (ICI) of prostaglandin E1 (PGE1) of German produce (Schwarz Pharma A. G.) have been tested for diagnosis of erectile disorders in 63 patients (age 32-71, the majority at the age 45-65) and for autotherapy in 22 patients. In 76% of males with erectile impotency PGE1 ICI in a dose 10-20 micrograms result in marked erection which emerged within 5-15 min after the injection and persisted for 90 min on the average in spite of ejaculation. 86% of patients suffering from erectile dysfunction found this method of impotency correction satisfactory as it warrants normal coitus in 91% of cases (dose regimen 10-20 micrograms). ICI of PGE1 in the above dose 1-2 times a week for 2 months is safe, entail no systemic and insignificant local side effects. The risk of priapism and cavernous body fibrosis is minimal. The duration of the effect is related to the dose. The above advantages make PGE1 superior to papaverin and phentolamine. PGE1 ICI are recommended as the treatment of choice for therapy of erectile dysfunctions.
Urologii͡a i nefrologii͡a
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ABSTRACT: Diagnostic potential of urodynamic tests was studied in 279 females with combined and complicated enuresis. 90 healthy females and 21 cadavers served control. The statistical analysis covered the following urodynamic parameters: cystometric volume, detrusor pressure in cystometric volume, functional urethral length, maximal intraurethral pressure, fluctuations of maximal intraurethral pressure. Isolated measurements of cystometric volume, functional urethral length and maximal intraurethral pressure failed to provide sufficient diagnostic information in effort enuresis, whereas cystometry was most efficient in diagnosis of detrusor instability. Registration of urethral pressure fluctuations in the maximal point allows detection of urethral instability. Combined urodynamic examination can not be fully rejected in patients with complicated and combined enuresis.
Urologii͡a i nefrologii͡a
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ABSTRACT: Unstable bladder was diagnosed in 15.9% of patients with post-operative problems with urination. It is suggested that the mechanism of urination defects in patients with benign prostatic hyperplasia may imply not only mechanical compression, stretching of the posterior urethra, changes in the urethrovesical angle, but also detrusor abnormalities. Ultrastructure of bladder muscles was studied in 6 patients with benign prostatic hyperplasia. In all cases bladder tissue underwent dystrophic, hypertrophic or atrophic changes. Lesions of the contractile apparatus of the bladder were associated with microcirculatory vessels sclerosis. The above ultrastructural alterations should be considered in combined therapy of patients with benign prostatic hyperplasia.
Urologii͡a i nefrologii͡a
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ABSTRACT: The authors studied potentialities of outpatient urodynamic monitoring in diagnosis of subclinical urination defects in females. The examination was made of 31 females aged 25-55 years (mean age 43.8 years) with complaints of pollakiuria, precipitant urination. Laboratory urodynamic investigation combined retrograde cystometry, profilometry and uroflowmetry (Jupiter 8000 Video produced by WIEST) and was followed by urodynamic monitoring (CAMSYS 6300 by WIEST). Standard combined urodynamic evaluation registered normal urodynamic parameters in 17 females, unstable urethra in 4, unstable detrusor in 7, unstable urethra and detrusor in 3 patients. The curves devised on the basis of the outpatient urodynamic monitoring data indicated that; normal urodynamics, unstable urethra, unstable detrusor, detrusor-sphincter dyssynergia, combined instability of urethra and detrusor, unstable detrusor plus detrusor-sphincter dyssynergia in 4, 10, 7, 3, 2, 2 females, respectively. 3 cases were ineligible. The above investigation promoted accurate diagnosis in 41.9% of cases. Outpatient monitoring is a method of choice in diagnosis of subclinical urination disorders.
Urologii͡a i nefrologii͡a
