Yoshitaka Kaneita

Publications (61)152.46 Total impact

• Article: Disorders of arousal and sleep-related bruxism among Japanese adolescents: a nationwide representative survey.

  Osamu Itani, Yoshitaka Kaneita, Maki Ikeda, Shuji Kondo, Ryuichiro Yamamoto, Yoneatsu Osaki, Hideyuki Kanda, Kenji Suzuki, Susumu Higuchi, Takashi Ohida
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  ABSTRACT: OBJECTIVE: The main objective of our study was to clarify the prevalence of disorders of arousal (confusional arousals, sleepwalking, sleep terrors) and sleep-related bruxism (teeth grinding) and their associated factors among Japanese adolescents. METHODS: Our study was designed as a cross-sectional sampling survey. The targets were students attending junior and senior high schools throughout Japan. The questionnaire asked for personal data and information on lifestyle, depressive state, and sleep status including the frequency of experiencing disorders of arousal and sleep-related bruxism. RESULTS: A total of 99,416 adolescents responded. The overall response rate was 63.7%, and 98,411 questionnaires were subjected to analysis. The prevalence of disorders of arousal was 7.1% (95% confidence interval [CI], 6.9-7.3%) among boys and 7.7% (95% CI, 7.5-7.9%) among girls. The prevalence of sleep-related bruxism was 2.3% (95% CI, 2.2-2.4%) among boys and 3.0% (95% CI, 2.8-3.2%) among girls. The factors associated with disorders of arousal were the grade in school, smoking habit, alcohol consumption, naptime (min), breakfast habit, participation in club activities, sleep duration, difficulty initiating sleep, nocturnal awakening, early morning awakening, subjective sleep assessment, snoring, decrease in positive feelings, and depression (all p<.001). The factors associated with sleep-related bruxism were gender, smoking habit, nocturnal awakening, snoring, early morning awakening, decrease in positive feelings, and depressive feelings (all p<.001). CONCLUSIONS: If disorders of arousal or sleep-related bruxism are observed in an adolescent, his or her smoking habit, alcohol consumption, sleep status, and depressive state should be considered.
  Sleep Medicine 05/2013; · 3.40 Impact Factor
• Article: Associations of Work Hours and Actual Availability of Weekly Rest Days with Cardiovascular Risk Factors.

  Osamu Itani, Yoshitaka Kaneita, Maki Ikeda, Shuji Kondo, Atsushi Murata, Takashi Ohida
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  ABSTRACT: Objectives: The aim of study was to determine the associations of work hours and actual availability of weekly rest days with the onset of lifestyle-related diseases such as obesity, hypertension, hypertriglyceridemia, low levels of high-density lipoprotein (HDL) cholesterol and hyperglycemia.Methods: For this longitudinal study, we used data from checkups conducted in 1999 and 2006 for 30,194 men who worked for a local public institution in Japan. We calculated the cumulative incidence rates of onset of obesity, hypertension, hyperglycemia, hypertriglyceridemia and low HDL cholesterol over this 7-year period and performed a χ(2) test to determine the association between the above diseases and work conditions (work hours and actual availability of weekly rest days) at the time of the baseline survey. We then performed multiple logistic regression analysis of the diseases that showed significant associations.Results: The adjusted odds ratio for the onset of hypertriglyceridemia in subjects who worked ≥9 hours was high (1.11 [95% CI: 1.02-1.22], p = 0.02) in comparison with those who worked <9 hours. The adjusted odds ratio for the onset of hypertriglyceridemia in subjects who could not often take weekly rest days was high (1.13 [95% CI: 1.01-1.27], p = 0.03) in comparison with those who were able to take most of the available weekly rest days off work.Conclusions: These results show that work hours and actual availability of weekly rest days independently predict the onset of hypertriglyceridemia. Working only regular hours and taking advantage of weekly rest days can contribute to the prevention of hypertriglyceridemia.
  Journal of Occupational Health 11/2012; · 1.55 Impact Factor
• Article: [Epidemiological studies of sleep disturbance in Japan].

  Osamu Itani, Maki Ikeda, Yoshitaka Kaneita, Takashi Ohida
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  ABSTRACT: Sleep has been a great interest in modern developed countries, epidemiological studies have been carried out extensively. In 2006, average sleep duration of the Japanese men, has been reported 7 hours 49 minutes (9 minutes shorter than 20 years ago) and women has been reported 7 hours 35 minutes (7 minutes shorter than 20 years ago). Sleep habits is affected by gender, age and also social factors and lifestyle. Thus, sleep-related problems have become an important public health issue in the society in developed countries. It is important to progress the preventive health promotion activities and results that are based on the development of future epidemiological studies of sleep.
  Nippon rinsho. Japanese journal of clinical medicine 07/2012; 70(7):1145-9.
• Article: Epidemiological study of sleep habits among four-and-a-half-year-old children in Japan.

  Maki Ikeda, Yoshitaka Kaneita, Shuji Kondo, Osamu Itani, Takashi Ohida
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  ABSTRACT: To date, only limited epidemiological data on the sleep habits of young children in Japan have been available. This study used representative samples to examine the sleep habits of four-and-a-half-year-old children in Japan. We used data from a nationwide cross-sectional survey. A member of each subject's family was asked to complete the questionnaire. The questionnaire included personal characteristics, sleep habits, and lifestyle. The data for 39,813 subject children (collection rate: 74.3%) were analyzed. The mean value of total sleep duration, night-time sleep duration, and daytime napping duration was 10 h 40 min 30 s, 9 h 53 min 0 s, and 46 min 24 s, respectively. The prevalence of daytime napping was 45.8%. Those whose total sleep duration was less than 10h accounted for 13.7% of the sample. The factors associated with high odds ratios for shorter total sleep duration were: living in a less populated area, long hours spent watching television, longer maternal work hours, and attending preschool. In attempting to devise ways of improving the sleep habits of young children, the lifestyles of both the children and their parents must be considered.
  Sleep Medicine 06/2012; 13(7):787-94. · 3.40 Impact Factor
• Article: The association between sleep problems and perceived health status: a Japanese nationwide general population survey.

  Ryuji Furihata, Makoto Uchiyama, Sakae Takahashi, Masahiro Suzuki, Chisato Konno, Kouichi Osaki, Michiko Konno, Yoshitaka Kaneita, Takashi Ohida, Toshiki Akahoshi, Shu Hashimoto, Tsuneto Akashiba
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  ABSTRACT: Sleep problems in humans have been reported to impact seriously on daily function and to have a close association with well-being. To examine the effects of individual sleep problems on physical and mental health, we conducted a nationwide epidemiological survey and examined the associations between sleep problems and perceived health status. Cross-sectional surveys with a face-to-face interview were conducted in August and September, 2009, as part of the Nihon University Sleep and Mental Health Epidemiology Project (NUSMEP). Data from 2559 people aged 20 years or older were analyzed (response rate 54.0%). Participants completed a questionnaire on perceived physical and mental health statuses, and sleep problems including the presence or absence of insomnia symptoms (i.e., difficulty initiating sleep [DIS], difficulty maintaining sleep [DMS], and early morning awakening [EMA]), excessive daytime sleepiness (EDS), poor sleep quality (PSQ), short sleep duration (SSD), and long sleep duration (LSD). The prevalence of DIS, DMS, and EMA was 14.9%, 26.6%, and 11.7%, respectively, and 32.7% of the sample reported at least one of them. At the complaint level, the prevalence of EDS, PSQ, SSD, and LSD was 1.4%, 21.7%, 4.0%, and 3.2%, respectively. Multiple logistic regression analyses revealed that DMS, PSQ, SSD, and LSD were independently associated with poor perceived physical health status; DIS, EDS, and PSQ were independently associated with poor perceived mental health status. This study has demonstrated that sleep problems have individual significance with regard to perceived physical or mental health status.
  Sleep Medicine 05/2012; 13(7):831-7. · 3.40 Impact Factor
• Article: Preferable forms of relaxation for health promotion, and the association between recreational activities and self-perceived health.

  Tadahiro Ohtsu, Yoshitaka Kaneita, Sayaka Aritake, Kazuo Mishima, Makoto Uchiyama, Tsuneto Akashiba, Naohisa Uchimura, Shigeyuki Nakaji, Takeshi Munezawa, Naoki Shimada, Akatsuki Kokaze, Takashi Ohida
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  ABSTRACT: Little research has been done on the association between relaxation and health. In the present study, by conducting a nationwide cross-sectional survey, we aimed to obtain scientific data on the preferable forms of relaxation for health promotion, and to clarify the associations between specific recreational activities and self-perceived mental and physical health. We selected 4,000 households by stratified random sampling from across Japan in November 2009 and used the interview method to collect data (number of subjects: 2,206). The questionnaire contained items on sleep, recreation status, recreational activities, and self-perceived mental and physical health status. We obtained responses from 1,224 adults (response rate: 55.5%). Insufficient rest from sleep, short sleep duration (<6 h/day), ineffective use of free time, and less free time used for activities other than rest showed independent positive associations with poor mental and physical health. The results of the logistic regression analyses showed significantly low adjusted odds ratios with regard to the status of poor mental and physical health for outings/walking among men (0.33 [95% confidence interval; 0.16-0.68] and 0.49 [0.26-0.90], respectively), and for community activities among women (0.19 [0.04-0.79] and 0.27 [0.09-0.77], respectively). Relaxation for the promotion of health should include both passive relaxation (rest) and active relaxation (recreation). In addition, ensuring sufficient sleep duration is important for passive relaxation, and engaging in outings/walking for men and community activities for women are important for active relaxation.
  Acta medica Okayama 02/2012; 66(1):41-51. · 0.84 Impact Factor
• Article: Mobile phone use does not discourage adolescent smoking in Japan.

  Yoneatsu Osaki, Takashi Ohida, Hideyuki Kanda, Yoshitaka Kaneita, Takuji Kishimoto
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  ABSTRACT: The possibility that smoking prevalence among junior and senior high school students may decrease with increasing mobile phone bill was reported by the mass media in Japan. We conducted a nationwide survey on adolescent smoking and mobile phone use in Japan in order to assess the hypothesis that mobile phone use has replaced smoking. A total of 70 junior high schools (response rate; 71%), and 69 high schools (90%) from all over Japan responded to 2005 survey. Students in the responding schools were asked to fill out an anonymous questionnaire about smoking behavior, mobile phone bill, and pocket money. Questionnaires were collected from 32,615 junior high school students and 48,707 senior high school students. The smoking prevalence of students with high mobile phone bill was more likely to be high, and that of students who used mobile phones costing 10,000 yen and over per month was especially high. When "quitters" were defined as students who had tried smoking but were not smoking at the time of survey, the proportion of quitters decreased as the mobile phone bill increased. The proportion of students who had smoking friends increased with the increase in the mobile phone bill per month. The hypothesis that the decrease in smoking prevalence among Japanese adolescents that has been observed in recent years is due to a mobile phone use can be rejected.
  Asian Pacific journal of cancer prevention: APJCP 01/2012; 13(3):1011-4. · 0.66 Impact Factor
• Article: Longitudinal study of parental smoking habits and development of asthma in early childhood.

  Miki Kanoh, Yoshitaka Kaneita, Megumi Hara, Shohei Harada, Yasuhiro Gon, Hiroshi Kanamaru, Takashi Ohida
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  ABSTRACT: This study examined the association between parental smoking habits and the development of asthma in early childhood by using representative samples. The survey subjects included all of the 53,575 babies born in Japan during the periods January 10-17 and July 10-17, 2001. The families of the subjects were asked to complete questionnaires that were delivered by post at 6 months, 1 year 6 months, 2 years 6 months, 3 years 6 months, and 4 years 6 months postpartum. The first survey contained questions regarding the smoking habits of the parents. The second to fifth surveys asked if the child had needed medical attention for the treatment of asthma. Data from 36,888 subjects (collection rate: 68.9%) were analyzed. The 4-year cumulative incidence of asthma was 12.0%. Maternal indoor smoking significantly increased the risk of asthma development in children, 4-year risk 14.4% vs. 11.7%, risk ratio=1.24, 95% CI: 1.11 to 1.38. No statistically significant association was found between paternal smoking and asthma development in children. In order to prevent the development of asthma in early childhood, it is necessary to formulate measures to stop or discourage maternal smoking.
  Preventive Medicine 10/2011; 54(1):94-6. · 3.22 Impact Factor
• Article: Association of current work and sleep situations with excessive daytime sleepiness and medical incidents among Japanese physicians.

  Yoshitaka Kaneita, Takashi Ohida
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  ABSTRACT: The aim of the present study was to clarify the current work and sleep situations of physicians in Japan and to clarify the association between these situations and excessive daytime sleepiness as well as medical incidents. A self-administered questionnaire survey was conducted among the members of the Japan Medical Association in 2008. The randomly selected subjects comprised 3,000 male physicians and 1,500 female physicians. Valid responses were obtained from 3,486 physicians (2,298 men and 1,188 women). Mean sleep duration was 6 h 36 min for men and 6 h 8 min for women. The prevalence of lack of rest due to sleep deprivation was 30.4% among men and 36.6% among women; the prevalence of insomnia was 21.0% and 18.1%, respectively; and the prevalence of EDS was 3.5%. The adjusted odds ratio for EDS was high for physicians who reported short sleep duration, lack of rest due to sleep deprivation, and a high frequency of on-call/overnight work. Physicians who had experienced a medical incident within the previous one month accounted for 19.0% of participants. The adjusted odds ratio for medical incidents was high for those subjected to long working hours, high frequency of on-call/overnight works, lack of rest due to sleep deprivation, and insomnia. In order to facilitate optimal health management for physicians as well as securing medical safety, it is important to fully consider the work and sleep situations of physicians.
  Journal of clinical sleep medicine: JCSM: official publication of the American Academy of Sleep Medicine 10/2011; 7(5):512-22. · 3.23 Impact Factor
• Article: Association of onset of obesity with sleep duration and shift work among Japanese adults.

  Osamu Itani, Yoshitaka Kaneita, Atsushi Murata, Eise Yokoyama, Takashi Ohida
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  ABSTRACT: The objective of this longitudinal epidemiological study was to investigate the association of risk factors for cardiovascular illness with sleep duration and shift work. This study used data obtained at medical checkups conducted in 1999 and 2006 for the employees of a local government organization in Japan (covering 21,693 male employees and 2109 female employees). The medical checkup data included (1) body measurements, (2) blood test parameters, and (3) replies to a self-administered questionnaire (inquiring about sleep duration, with or without shift work, etc.). On the basis of these data, we conducted multiple logistic regression analyses to study the association between the risk of new-onset obesity, hypertension, hyperglycemia, hypertriglyceridemia, and hypo-high density lipoprotein (HDL) cholesterolemia and shift work as well as sleep duration. Among the male subjects who were engaged in shift work, the relative risk of new-onset obesity for those with a sleep duration of less than 5 h was 1.30 (95% CI, 1.14-1.49) higher than for those with sleep duration of 5-7 h. Furthermore, analysis using both engagement in shift work and sleep duration as dependent variables showed that the relative risks of new-onset obesity for those with a sleep duration of less than 5 h were 1.20 (95% CI, 1.09-1.32) for men and 1.7 (95% CI, 1.11-2.87) for women. Short sleep duration is associated with onset of obesity.
  Sleep Medicine 03/2011; 12(4):341-5. · 3.40 Impact Factor
• Article: [Development of depressive symptoms in middle-aged and aged populations and its relationship with stresses in their daily lives--a cross-sectional study of a large population group representing general population in Japan].

  Tatsuhiko Kaji, Kazuo Mishima, Shingo Kitamura, Minori Enomoto, Yukihiro Nagase, Lan Li, Yoshitaka Kaneita, Takashi Ohida, Toru Nishikawa, Makoto Uchiyama
  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 01/2011; 113(7):653-61.
• Article: The association between use of mobile phones after lights out and sleep disturbances among Japanese adolescents: a nationwide cross-sectional survey.

  Takeshi Munezawa, Yoshitaka Kaneita, Yoneatsu Osaki, Hideyuki Kanda, Masumi Minowa, Kenji Suzuki, Susumu Higuchi, Junichiro Mori, Ryuichiro Yamamoto, Takashi Ohida
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  ABSTRACT: The objective of this study was to examine the association between the use of mobile phones after lights out and sleep disturbances among Japanese adolescents. This study was designed as a cross-sectional survey. The targets were students attending junior and senior high schools throughout Japan. Sample schools were selected by cluster sampling. Self-reported anonymous questionnaires were sent to schools for all students to fill out. A total of 95,680 adolescents responded. The overall response rate was 62.9%, and 94,777 questionnaires were subjected to analysis. N/A. Daily mobile phone use, even if only for a brief moment every day, was reported by 84.4%. Moreover, as for use of mobile phones after lights out, 8.3% reported using their mobile phone for calling every day and 17.6% reported using it for sending text messages every day. Multiple logistic regression analysis showed that mobile phone use for calling and for sending text messages after lights out was associated with sleep disturbances (short sleep duration, subjective poor sleep quality, excessive daytime sleepiness, and insomnia symptoms) independent of covariates and independent of each other. This study showed that the use of mobile phones for calling and for sending text messages after lights out is associated with sleep disturbances among Japanese adolescents. However, there were some limitations, such as small effect sizes, in this study. More studies that examine the details of this association are necessary to establish strategies for sleep hygiene in the future.
  Sleep 01/2011; 34(8):1013-20. · 5.05 Impact Factor
• Article: Association between depression and insomnia subtypes: a longitudinal study on the elderly in Japan.

  Eise Yokoyama, Yoshitaka Kaneita, Yasuhiko Saito, Makoto Uchiyama, Yoko Matsuzaki, Tetsuo Tamaki, Takeshi Munezawa, Takashi Ohida
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  ABSTRACT: To examine the association between depression and three subtypes of insomnia, namely, difficulty initiating sleep (DIS), early morning awakening (EMA), and difficulty maintaining sleep (DMS). Cross-sectional and longitudinal study. Community dwellers in Japan. Nationally representative samples of adults aged 65 and over (total N=4,997) were selected by a multistage stratified random sampling method in 1999 and were interviewed face-to-face in 1999, 2001, 2003, and 2006. Those who responded to the 3rd survey conducted in 2003 and the 4th survey conducted in 2006 were used in this study. Depression was evaluated according to the 11-item short form of the CES-D scale at 2 points in time. Insomnia subtypes were assessed by self-reported measures. A logistic regression was employed to examine the association between insomnia subtypes and the presence of depression, controlling for relevant factors. A cross-sectional analysis based on the 2003 data demonstrated statistically significant odds ratios (ORs) for DIS and EMA. In the longitudinal study, DIS at the time of the 3rd survey was found to be significantly related to the presence of depression at the time of the 4th survey, with an odds ratio (95%CI) of 1.592 (1.012 to 2.504). EMA (OR 1.070; 95% CI, 0.664 to 1.723) and DMS (OR 1.215; 95% CI, 0.860 to 1.716), however, were not found to be significantly related to the presence of depression. The longitudinal study revealed a statistically significant relationship, controlling for other relevant factors, between DIS and the presence of depression three years later, but not between EMA or DMS and depression. Based on our findings, we recommend that the association between insomnia subtypes and depression be studied longitudinally in clinical settings.
  Sleep 12/2010; 33(12):1693-702. · 5.05 Impact Factor
• Article: Clarification of the factor structure of the 12-item General Health Questionnaire among Japanese adolescents and associated sleep status.

  Hiroyuki Suzuki, Yoshitaka Kaneita, Yoneatsu Osaki, Masumi Minowa, Hideyuki Kanda, Kenji Suzuki, Kiyoshi Wada, Kenji Hayashi, Takeo Tanihata, Takashi Ohida
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  ABSTRACT: If the factors affecting the mental health status of adolescents and their association with sleep status could be clarified, this information would be helpful for formulating lifestyle and healthcare guidance for the promotion of healthy growth and the prevention of mental problems in these individuals. The purpose of this study was to clarify (1) the factor structure of the 12-item General Health Questionnaire (GHQ-12), and (2) the associations between the factors extracted from this questionnaire and lifestyle, in particular sleep status, by using a representative sample population of Japanese adolescents. One hundred three thousand sixty hundred fifty self-administered questionnaires were collected from students enrolled in junior high and high schools in Japan. Of these questionnaires, 99,668 were analyzed. Sleep duration, subjective sleep assessment, bedtime, and insomnia symptoms of these students over the past month were studied to investigate sleep status. The factor analyses yielded two factors: depression/anxiety and loss of positive emotion. Sleep duration of less than 7h was found to be associated with both depression/anxiety and loss of positive emotion, whereas sleep duration of 8h or more was associated only with loss of positive emotion. Subjective sleep assessment and insomnia symptoms were associated with both depression/anxiety and loss of positive emotion. It was demonstrated that two underlying factors of mental health status were associated with differences in sleep status. In order to improve the mental health status of adolescents, it is important to provide guidance about sleep and lifestyle habits according to the mental health status of the individual.
  Psychiatry Research 12/2010; 188(1):138-46. · 2.52 Impact Factor
• Article: Self-help behaviors for sleep and depression: a Japanese nationwide general population survey.

  Ryuji Furihata, Makoto Uchiyama, Sakae Takahashi, Chisato Konno, Masahiro Suzuki, Kouichi Osaki, Yoshitaka Kaneita, Takashi Ohida
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  ABSTRACT: The aim of this study was to examine the relationship between self-help behaviors for sleep (SHBS) and depression among the general adult population in Japan. The survey was conducted in June 2000 using self-administered questionnaires for subjects living in 300 communities randomly selected throughout Japan. A total of 24,686 responses were analyzed from individuals aged 20 years or older. The Center for Epidemiologic Studies Depression Scale was used to assess the prevalence of depression with two cut-off points: 16 and 25. Details of 6 types of SHBS were asked, based on given examples of actual behavior and frequency. After adjusting for sociodemographic variables, sleep problems and other SHBS, multiple logistic regression analyses revealed that "snacking on food and/or beverages" was independently associated with an increased odds ratio for depression, whereas "maintaining lifestyle regularity" was independently associated with a decreased odds ratio for depression. "Drinking alcoholic beverages," "having a bath," and "reading books or listening to music" were associated with an increased odds ratio for depression in crude analyses, but the significance of the association disappeared after adjusting for sociodemographic variables, sleep problems and other SHBS. Complex constructs are being correlated. These results suggest that individual SHBS are differentially associated with depression, thus providing important clues for establishing sleep hygiene for treatment and prevention of depression.
  Journal of affective disorders 10/2010; 130(1-2):75-82. · 3.76 Impact Factor
• Article: Age verification cards fail to fully prevent minors from accessing tobacco products.

  Hideyuki Kanda, Yoneatsu Osaki, Takashi Ohida, Yoshitaka Kaneita, Takeshi Munezawa
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  ABSTRACT: Proper age verification can prevent minors from accessing tobacco products. For this reason, electronic locking devices based on a proof-of age system utilising cards were installed in almost every tobacco vending machine across Japan and Germany to restrict sales to minors. We aimed to clarify the associations between amount smoked by high school students and the usage of age verification cards by conducting a nationwide cross-sectional survey of students in Japan. This survey was conducted in 2008. We asked high school students, aged 13-18 years, in Japan about their smoking behaviour, where they purchase cigarettes, if or if not they have used age verification cards, and if yes, how they obtained this card. As the amount smoked increased, the prevalence of purchasing cigarettes from vending machines also rose for both males and females. The percentage of those with experience of using an age verification card was also higher among those who smoked more. Somebody outside of family was the top source of obtaining cards. Surprisingly, around 5% of males and females belonging to the group with highest smoking levels applied for cards themselves. Age verification cards cannot fully prevent minors from accessing tobacco products. These findings suggest that a total ban of tobacco vending machines, not an age verification system, is needed to prevent sales to minors.
  Tobacco control 10/2010; 20(2):163-5. · 3.85 Impact Factor
• Article: Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome.

  Toshiki Akahoshi, Akihito Uematsu, Tsuneto Akashiba, Kenichi Nagaoka, Kouji Kiyofuji, Seiji Kawahara, Tomohiro Hattori, Yoshitaka Kaneita, Takayuki Yoshizawa, Noriaki Takahashi, Makoto Uchiyama, Shu Hashimoto
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  ABSTRACT: Several features of OSA syndrome suggest that it is a manifestation of the metabolic syndrome (MS). In this study, we investigated the prevalence of the MS among male Japanese patients with OSA, as well as the relationship between OSA in non-obese patients and components of the MS other than obesity (hypertension, dyslipidaemia and glucose intolerance). The study included 416 Japanese men who were diagnosed as having OSA by polysomnography. Among these, 101 non-obese patients were selected and the severity of OSA, as well as the prevalence of hypertension, dyslipidaemia and glucose intolerance, was assessed. The MS was associated with OSA in 218/416 patients (52.4%). A significant increase in the prevalence of the MS was associated with increased severity of OSA, as categorized according to AHI. In the non-obese patients with OSA (mean age 57.6 years, BMI 22.7 kg/m(2), AHI 34.3 events/h), hypertension, dyslipidaemia and glucose intolerance were identified in 70 (69.3%), 43 (42.6%) and 20 patients (19.8%), respectively. At least two of these factors were identified in 40 patients (39.6%). Non-obese patients with severe OSA had a significantly higher prevalence of two or more of these factors (33/59 patients, 55.9%). Although Asians are generally less obese than Caucasians, the prevalence of the MS was high among Japanese patients with OSA, and even among non-obese patients, OSA was associated with risk factors for the MS.
  Respirology 10/2010; 15(7):1122-6. · 2.42 Impact Factor
• Article: Nightmare and sleep paralysis among Japanese adolescents: a nationwide representative survey.

  Takeshi Munezawa, Yoshitaka Kaneita, Yoneatsu Osaki, Hideyuki Kanda, Tadahiro Ohtsu, Hiroyuki Suzuki, Masumi Minowa, Kenji Suzuki, Susumu Higuchi, Junichirou Mori, Takashi Ohida
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  ABSTRACT: The objective of this study was to clarify the prevalence of nightmares and sleep paralysis and associated factors among Japanese adolescents. This study was designed as a cross-sectional sampling survey. The targets were junior and senior high schools throughout Japan. Self-reported anonymous questionnaires were sent to schools for all students to complete. A total of 90,081 questionnaires were analyzed. The overall response rate was 62.6%, and the prevalence of nightmares and sleep paralysis was 35.2% and 8.3%, respectively. Multiple logistic analyses revealed that female sex, drinking alcohol, poor mental health, difficulty initiating sleep, low subjective sleep assessment, presence of excessive daytime sleepiness, and presence of sleep paralysis had higher odds ratios than others for nightmares. Male sex, poor mental health, drinking alcohol, taking a long daytime nap, early or late bedtime, difficulty initiating sleep, low subjective sleep assessment, presence of excessive daytime sleepiness, and presence of nightmares had higher odds ratios than other factors for sleep paralysis. This study has revealed the prevalence of nightmares and sleep paralysis among Japanese adolescents. Furthermore, the results of this study suggest that it is important to maintain regular sleep habits for preventing these symptoms. We propose that health education about regular sleep habits should be promoted among Japanese adolescents.
  Sleep Medicine 09/2010; 12(1):56-64. · 3.40 Impact Factor
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  Available from: okayama-u.ac.jp

  Article: General consumer awareness of warnings regarding the consumption of alcoholic beverages.

  Tadahiro Ohtsu, Akatsuki Kokaze, Naoki Shimada, Yoshitaka Kaneita, Takako Shirasawa, Hirotaka Ochiai, Hiromi Hoshino, Masahiro Takaishi
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  ABSTRACT: Over the past two decades, the liquor industry in Japan has strived to address alcohol-related problems through initiatives such as warnings in the various media. In this study, we conducted an Internet-based questionnaire survey to examine general consumer awareness of such warnings, and the media by which they are conveyed, on the consumption of alcoholic beverages. A total of 985 subjects (males: 487, females: 498) in age groups ranging from 20s to 70s responded (response rate: 22.4%). The awareness rates for warnings regarding underage drinking, drunk driving, and drinking during pregnancy, and those for messages encouraging moderation in drinking, were 96.4%, 83.7%, 59.6%, and 45.5%, respectively. Logistic regression analysis adjusted for habitual alcohol consumption demonstrated significant gender- and/or age-based differences in the rates of awareness of warnings and the media publicizing them. For example, the odds ratio of awareness among women of warnings against underage drinking was significantly higher than that of awareness among men. Issues that must be addressed in the future include:(1) increasing public awareness about messages regarding drinking during pregnancy and drinking in moderation;(2) reviewing the wording of warnings to make them more effective;and (3) devising and employing, on a regular basis, more effective means of transmitting messages in consideration of gender and age.
  Acta medica Okayama 08/2010; 64(4):225-32. · 0.84 Impact Factor
• Article: Relationship between late-life depression and life stressors: large-scale cross-sectional study of a representative sample of the Japanese general population.

  Tatsuhiko Kaji, Kazuo Mishima, Shingo Kitamura, Minori Enomoto, Yukihiro Nagase, Lan Li, Yoshitaka Kaneita, Takashi Ohida, Toru Nishikawa, Makoto Uchiyama
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  ABSTRACT: The purpose of the present study was to clarify the relationship between late-life depression and daily life stress in a representative sample of 10 969 Japanese subjects. Data on 10 969 adults aged > or =50 who participated in the Active Survey of Health and Welfare in 2000, were analyzed. The self-administered questionnaire included items on 21 reasons for life stressors and the magnitude of stress, as well as the Japanese version of the Center for Epidemiologic Studies Depression Scale (CES-D). The relationship between the incidence of life stressors and mild-moderate (D(16)) and severe (D(26)) depressive symptoms was examined using logistic regression analysis. A total of 21.9% of subjects had D(16) symptoms, and 9.3% had D(26) symptoms. Further, increased age and being female were associated with more severe depressive state. Logistic regression analysis indicated that the strongest relationship between both the incidence of D(16) and D(26) symptoms and life stressors stemmed from 'having no one to talk to' (odds ratio = 3.3 and 5.0, respectively). Late-life depression was also associated with 'loss of purpose in life', 'separation/divorce', 'having nothing to do', 'health/illness/care of self', and 'debt'. There is a relationship between late-life depression and diminished social relationships, experiences involving loss of purpose in life or human relationships, and health problems in the Japanese general population.
  Psychiatry and Clinical Neurosciences 08/2010; 64(4):426-34. · 2.13 Impact Factor