Publications (8)33.43 Total impact
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Article: Symptomatic atrial fibrillation as the first symptom of a giant left atrial appendage aneurysm
Clinical Research in Cardiology 04/2012; 95(11):614-616. · 2.95 Impact Factor -
Article: Radiation dose exposure of computed tomography coronary angiography: comparison of dual-source, 16-slice and 64-slice CT.
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ABSTRACT: Dual-source CT (DSCT) promises a significant reduction of radiation dose exposure for coronary CT angiography (CTA). Large studies on radiation dose estimates are rare. To compare radiation dose estimates of DSCT with 16- and 64-slice multidetector CT (MDCT) for non-invasive coronary angiography. Retrospective data analysis was performed on 292 patients: 56 patients were examined with 16-slice MDCT, 38 patients with 64-slice MDCT and 202 patients using DSCT. The effective dose (ED) estimates were calculated for all patients from the dose-length product and the conversion factor k (0.017 mSv/mGy/cm), as recommended by current guidelines. The mean (SD) ED for patients examined by 16-slice MDCT was 9.8 (1.8) mSv, for 64-slice MDCT 8.6 (2.8) mSv and for DSCT 11.4 (7.2) mSv. With a protocol of 100 kV tube voltage and 110 ms ECG pulsing window the mean (SD) ED was 3.8 (1.7) mSv for DSCT scanning. When DSCT with a tube voltage of 100 kV was used, a significant inverse correlation between heart rate and radiation dose exposure was found. When standard protocols for coronary CTA with 16-, 64-slice MDCT and DSCT scanners are used, the radiation dose is still high. However, using optimised and individually adjusted protocols low estimated radiation doses can be achieved.Heart (British Cardiac Society) 06/2009; 95(16):1337-42. · 4.22 Impact Factor -
Article: Atrial septal defects type II: noninvasive evaluation of patients before implantation of an Amplatzer Septal Occluder and on follow-up by magnetic resonance imaging compared with TEE and invasive measurement.
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ABSTRACT: The purpose of this study was to evaluate morphological and functional MRI of atrial septal defects (ASD) before and after interventional occlusion by the Amplatzer Septal Occluder (AOC) in comparison to trans-oesophageal echocardiography (TEE), invasive balloon measurement (IVBM) and cardiac catheterisation (QCC). Sixty patients with an ASD type II were enrolled. They underwent TEE, IVBM, QCC and MRI at 1.5T. Cine gradient echo, steady-state free precession sequences and a gradient echo phase contrast sequence were used. In MRI, pulmonary-to-systemic flow ratio (Qp/Qs) was calculated and compared with the QCC Qp/Qs ratio. Qp/Qs ratio in baseline MRI examination was 1.56 +/- 0.29 (range: 1.05-2.2) and in QCC 1.71 +/- 0.30 (range: 1.2-2.4) with a significant correlation (R = 0.65, P < 0.01). Defect size on MRI was 15.3 +/- 7.4 mm (range: 3-30 mm), in TEE 14.3 +/- 4.9 mm (range: 4-24 mm), and the balloon stretched diameter in IVBM was 23.4 +/- 4.2 mm (range: 14-32 mm). Correlation between defect size in MRI vs. TEE was R = 0.67 (P < 0.01) and MRI vs. IVBM was R = 0.77 (P < 0.01). Right ventricular volumes decreased after intervention. MRI is an accurate noninvasive test for diagnosis, planning and follow-up after interventional ASD occlusion using an AOC.European Radiology 07/2008; 18(11):2406-13. · 3.22 Impact Factor -
Article: Radiation dose exposure in multislice computed tomography of the coronaries in comparison with conventional coronary angiography.
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ABSTRACT: Radiation dose exposure is increased in multislice spiral computed tomography (MSCT) compared to conventional coronary angiography (CXA). Retrospective data analysis of 56 patients (66+/-8 years, 49 males, body surface area 1.98+/-0.18 m(2), heart rate 64+/-11 bpm) who underwent MSCT and CXA was performed (MSCT: 16-slice scanner, rotation time 0.375 s, 120 kV, ECG-pulsing; CXA: current technique system build in 2003). Ten patients with bypass grafts underwent bypass angiography in CXA and MSCT. To compare the radiation doses of both investigations, the effective dose (ED) was chosen as the analysis variable. The mean ED for MSCT was 9.76+/-1.84 mSv (n=46) for patients without bypass grafts; with calcium scoring the mean ED was 12.46+/-2.23 mSv (n=46). In comparison, the mean ED of CXA was 2.60+/-1.27 mSv (n=46) for patients without bypass grafts; with bypass grafts (n=10) the mean ED for MSCT was 12.95+/-1.75 mSv, for CXA of 6.27+/-4.04 mSv, respectively. In MSCT heart rates of <or=60 bpm resulted in lower mean ED than heart rates of >60 bpm (8.86+/-1.24 mSv versus 10.53+/-1.86 mSv). MSCT is still associated with a higher radiation dose exposure than CXA. The radiation dose relation is more favorable for MSCT than for CXA in patients with bypass grafts in comparison to patients without bypass grafts. This study emphasizes the importance of dose reduction techniques.International journal of cardiology 03/2008; 124(3):307-11. · 7.08 Impact Factor -
Article: Use of automatic exposure control in multislice computed tomography of the coronaries: comparison of 16-slice and 64-slice scanner data with conventional coronary angiography.
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ABSTRACT: To evaluate the radiation-dose-reduction potential of automatic exposure control (AEC) in 16-slice and 64-slice multislice computed tomography (MSCT) of the coronary arteries (computed tomography angiography, CTA) in patients. The rapid growth in MSCT CTA emphasises the necessity of adjusting technique factors to reduce radiation dose exposure. A retrospective data analysis was performed for 154 patients who had undergone MSCT CTA. Group 1 (n = 56) had undergone 16-slice MSCT without AEC, and group 2 (n = 51), with AEC. In group 1, invasive coronary angiography (ICA) had been performed in addition. Group 3 (n = 47) had been examined using a 64-slice scanner (with AEC, without ECG-triggered tube current modulation). In group 1, the mean (SD) effective dose (ED) for MSCT CTA was 9.76 (1.84) mSv and for ICA it was 2.6 (1.27) mSv. In group 2, the mean ED for MSCT CTA was 5.83 (1.73) mSv, which signifies a 42.8% dose reduction for CTA by the use of AEC. In comparison to ICA, MSCT CTA without AEC shows a 3.8-fold increase in radiation dose, and the radiation dose of CTA with AEC was increased by a factor of 1.9. In group 3, the mean ED for MSCT CTA was 13.58 (2.80) mSV. This is the first study to show the significant dose-reduction potential (42.8%) of AEC in MSCT CTA in patients. This relatively new technique can be used to optimise the radiation dose levels in MSCT CTA.Heart (British Cardiac Society) 09/2007; 93(9):1040-3. · 4.22 Impact Factor -
Article: Multiple episodes of a transient global left ventricular dysfunction reminiscent to apical ballooning.
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ABSTRACT: A new cardiac syndrome with transient left ventricular dysfunction has been recently reported and is referred to as Tako-Tsubo cardiomyopathy, which is characterized by a transient akinesia of the apex and compensatory basal hyperkinesis. Today, the etiology remains unknown. We report for the first time of a patient with multiple episodes of a transient global left ventricular dysfunction which is reminiscent to apical ballooning. These episodes were always preceded by severe emotional stress proposing a potential common pathomechanism.Cardiology 02/2007; 108(1):1-3. · 1.71 Impact Factor -
Article: Release pattern of cardiac biomarkers in left ventricular apical ballooning.
International journal of cardiology 02/2007; 115(1):128-9. · 7.08 Impact Factor -
Article: Cardiac metastasis of a renal cell adenocarcinoma investigated by cardiac magnetic resonance imaging
Clinical Research in Cardiology 01/2006; 95(9):492-495. · 2.95 Impact Factor
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2008
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Universität Hamburg
- Department of Diagnostic and Interventional Neuroradiology
Hamburg, Hamburg, Germany
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