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Publications (4)0 Total impact

  • Lin Lin, Feng-ri Cao, Gui-yan Liu
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    ABSTRACT: To understand the status of the expanded program on immunization (EPI) ralated to the immunization site at towns, and provide reliable base for it. Questionnaires about the status of information system were filled out by all immunization site at towns, and descriptive method was applied to analyze the EPI and infomation service, personnel, equipments, funds and information system status. Among all the immunigation site in Jilin province, monthly running accounts for 75.85%, vaccination in designated sites and homes accounts for 46.77% and 40.41% respectively; the personnel whose age was under 45-year-old accounts for 77.31%, and the personnel whose work experience was more than 3 years accounted for 86.98%, 39.15% of all the personnel had little knowledge about using computer, and 46.93% of which had basic knowledge. 7.23% of all the immunigation site at towns had computers for EPI management, and 5.53% of which had optical cable or ADSL network service. Funds for EPI related information system and management at all immunization site at towns was little. Computers should be equipped as soon as possible, and computer related training should be enhanced; funds input should be increased. Pilot project about EPI related information network at county level should be carried out to obtain useful experience and to improve the information system so that the EPI related information network could be expanded.
    Zhongguo ji hua mian yi = Chinese journal of vaccines and immunization 06/2009; 15(3):274-5.
  • Gui-yan Liu, Li-xia Wang, Xin Chang
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    ABSTRACT: This project is designed for understand poliomyelitis (Polio) neutralization antibody level in the the border areas in Jilin province. 263 serum samples were collected from age groups of under 1-year-old, 1-2, 3-4, 5-6, 7-14, 15-19 and above 20-years-old. Microplate neutralization test was used to determine antibody level. Positive rates of neutralization antibody against Polio type I, II, III were 94.98%, 94.59%, 92.28%. The geometric mean titre of Polio type I, II, III were 1:40.53, 1:29.68, 1:20.71 respectively,which was decreased with the age increasing. The population especially the population under 15-years-old lived in places that near the border in Jilin province had good immunity barriar against poliomyelitis.
    Zhongguo ji hua mian yi = Chinese journal of vaccines and immunization 06/2009; 15(3):249-50.
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    ABSTRACT: A new simple RT-LAMP method was applied to detect measles virus nucleic acid and compared with nest-RT-PCR. Compare the detection rate of the RT-LAMP method with that of nest-RT-PCR by detecting measles virus nucleic acid from measles virus and clinical samples. The nucleic acid positive rates of all 23 strains of measles virus are all 100% by the two methods. But to the detection of 18 clinical samples which are negative in measles isolation, the nest-RT-LAMP showed 56.52% positive rate of nucleic acid of measles virus and nest-RT-PCR showed 47.83%. RT-LAMP is more sensitive than nest-RT-PCR.
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 01/2009; 22(6):403-5.
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    ABSTRACT: To study the genotype and gene characterization of measles wild viruses circulated in Jilin provinces, and to provide scientific evidences for setting down controlling and preventing strategy and measures. 38 strains of measles virus isolated in 2001-2006 were genotyped by RT-PCR-RFLP, some strains of measles virus in Jilin province were chosen for the phylogenetic analysis and for the homology analysis of nucleotide and amino acid sequences. All the 38 strains of measles virus were identified as H1 genotype by RT-PCR-RFLP, and 29 strains of them were identified further as H1 a by sequence analysis. The homology of nucleotide was 88.0%-89.4% and the homology of amino acid was 91.8%-92.7% .The average diversity was less than 1.4%. The measles virus of H1a genotype was the circulating virus within recent years in Jilin province. There were the same measles virus strains circulating and transmitting at different years and also the different H1a measles virus strains co-circulating at the same year. There were the same transmission chain caused by the same measles virus with other provinces.
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 01/2009; 22(6):409-12.