S D Calobrisi

Mayo Clinic - Rochester, Rochester, Minnesota, United States

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Publications (6)18.36 Total impact

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    ABSTRACT: Telemedicine has the potential to revolutionize the delivery of dermatologic care to underserved areas. Our purpose was to compare diagnoses from two types of dermatology consultations: telemedicine using store-and-forward (SAF) technology, and traditional face-to-face (FTF) office visits. Skin conditions were imaged with a consumer-grade digital camera. A standardized template was used to collect historical data. Information was stored in a secured database for access by 2 or 3 board-certified dermatologists. Results from the FTF visit were used to assess the accuracy of the SAF diagnoses. A total of 106 dermatologic conditions in 92 patients were included. Concordance between FTF and SAF diagnoses was high, ranging from 81% to 89% for all 3 dermatologists. Clinically relevant disagreement occurred in only 4% to 8% of cases. Remaining disagreements did not affect patient care. Diagnostic confidence and image quality affected agreement. When cases of high confidence were analyzed separately, agreement increased to 88% to 100%. This increase was substantiated by means of a chi-square test between the high confidence and low confidence groups, which demonstrated statistical significance (P <. 005) for all dermatologists. Similarly, when cases of above average image quality were considered, agreement increased to 84% to 98%. Again this difference was substantiated by means of a chi-square test between adequate and poor images, with statistical significance for two dermatologists (P <.001). Accuracy was comparable between disease types with the exception of benign neoplasms, which demonstrated agreement of 22% to 46%. These data support the use of existing digital technology to construct an accurate SAF teledermatology system. The inexpensive camera and widely available computer equipment make this an extremely affordable system. Furthermore, participating dermatologists appear well aware of system limitations, as reflected in the increased agreement for high confidence cases. Additional investigation of the accuracy of teledermatology for benign neoplasms is warranted.
    Journal of the American Academy of Dermatology 05/2000; 42(5 Pt 1):776-83. · 4.91 Impact Factor
  • M G Liang, J A Rooney, K H Rhodes, S D Calobrisi
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    ABSTRACT: Cutaneous tuberculosis remains a rare entity in the United States. We describe a case of cutaneous tuberculosis in a child.
    Journal of the American Academy of Dermatology 12/1999; 41(5 Pt 2):860-2. · 4.91 Impact Factor
  • S D Calobrisi, E Baselga, E S Miller, N B Esterly
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    ABSTRACT: A 14-year-old adolescent girl presented with a 2-year history of an exquisitely tender, vegetating cheilitis. Because of this, she was unable to drink fluids and was repeatedly hospitalized for dehydration and pain management. Lip and skin biopsies, as well as multiple laboratory studies did not support a definitive diagnosis. After 2 years, a diagnosis of factitial cheilitis was finally established.
    Pediatric Dermatology 01/1999; 16(1):12-5. · 1.04 Impact Factor
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    ABSTRACT: Bullous pemphigoid is a chronic immunobullous disease of the elderly. Classically, tense, pruritic blisters develop on normal or erythematous skin. These may be preceded by a prodromal pruritic, urticarial, or eczematous eruption. Occasionally, patients may develop generalized pruritus without blisters as a prodrome of bullous pemphigoid. The records of the patients were reviewed. Biopsy specimens were studied by light and immunofluorescence microscopy. Serum specimens were studied by indirect immunofluorescence techniques including the salt-split skin technique. We studied six elderly patients presenting with generalized pruritus as the dominant or single presenting feature of early bullous pemphigoid. Two of the six had rare vesicles at presentation. All had excoriations and one each presented with minimal urticarial or eczematous papules. Routine skin biopsies were largely nonspecific. All patients had confirmation of their diagnosis by either indirect or direct immunofluorescence testing or both. All six patients had their disease completely controlled by their treatment. The clinical presentation of the six patients in our series and the eight previously reported patients should be regarded as an unusual prodromal manifestation of bullous pemphigoid characterized by generalized pruritus without primary skin lesions. This presentation could be described as "pruritic pemphigoid," because it joins the remarkable clinical finding of generalized pruritus with the underlying diagnosis of bullous pemphigoid. Elderly patients with severe or persistent unexplained generalized pruritus merit immunofluorescence testing to exclude bullous pemphigoid as the cause of the generalized pruritus. Establishing an early diagnosis permits the prompt institution of effective therapy with dapsone or systemic corticosteroids with an excellent prognosis for complete control of the disease.
    International Journal of Dermatology 08/1998; 37(7):508-14. · 1.34 Impact Factor
  • S D Calobrisi, B A Drolet, N B Esterly
    Pediatrics 04/1998; 101(3 Pt 1):471-3. · 5.12 Impact Factor
  • S D Calobrisi, J S Garland, N B Esterly
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    ABSTRACT: Lipoblastomatosis is a benign tumor of embryonic fat that is more common in male infants. It occurs more frequently in the soft tissues of the extremities. The diagnosis is made by biopsy, which shows globules of lipocytes and lipoblasts mixed with spindled and myxoid cells. MRI demonstrates fat infiltrating fascia and muscle. The infant described had clinical, histologic, and radiologic findings consistent with this diagnosis. Because of concern that total excision would compromise function, a debulking procedure is planned.
    Pediatric Dermatology 01/1998; 15(3):210-3. · 1.04 Impact Factor

Publication Stats

120 Citations
18.36 Total Impact Points


  • 1998–2000
    • Mayo Clinic - Rochester
      • Department of Dermatology
      Rochester, Minnesota, United States
    • Mayo Foundation for Medical Education and Research
      • Department of Dermatology
      Scottsdale, AZ, United States
  • 1999
    • Medical College of Wisconsin
      Milwaukee, Wisconsin, United States