Carme Solé

Publications (10)20.65 Total impact

• Source

  Available from: Mariona Nadal

  Article: Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress.

  Carme Solé, Mariona Nadal-Ribelles, Claudine Kraft, Matthias Peter, Francesc Posas, Eulàlia de Nadal
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  ABSTRACT: Protein ubiquitylation is a key process in the regulation of many cellular processes. The balance between the activity of ubiquitin ligases and that of proteases controls the level of ubiquitylation. In response to extracellular stimuli, stress-activated protein kinases (SAPK) modulate gene expression to maximize cell survival. In yeast, the Hog1 SAPK has a key role in reprogramming the gene expression pattern required for cell survival upon osmostress. Here, we show that the Ubp3 ubiquitin protease is a target for the Hog1 SAPK to modulate gene expression. ubp3 mutant cells are defective in expression of osmoresponsive genes. Hog1 interacts with and phosphorylates Ubp3 at serine 695, which is essential to determine the extent of transcriptional activation in response to osmostress. Furthermore, Ubp3 is recruited to osmoresponsive genes to modulate transcriptional initiation as well as elongation. Therefore, Ubp3 activity responds to external stimuli and is required for transcriptional activation upon osmostress.
  The EMBO Journal 01/2011; 30(16):3274-84. · 9.20 Impact Factor
• Source

  Available from: Sacramento Pinazo

  Article: Older people's university students in Spain: a comparison of motives and benefits between two models

  FELICIANO VILLAR, SACRAMENTO PINAZO, CARME TRIADÓ, MONTSERRAT CELDRÁN, CARME SOLÉ
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  ABSTRACT: This study examines both the motives for and the benefits of attending a university programme for older people (UPOP) in Spain, and how they vary with the type of UPOP. Two UPOP models were assessed: The ‘Older People's Classes’ of the University of Barcelona, which is organised as a lecture course, and the ‘University of Experience’ at the University of Valencia, which is a three- or four-year variant of regular university degrees. A sample of 321 older students (mean age 67.5 years) was gathered from the two UPOPs, 161 participants from the former and 157 from the latter. The findings suggest that expressive motives such as acquiring knowledge, expanding the mind or learning for the joy of learning were the most important reasons for joining a UPOP, and that among the perceived benefits from taking classes at university featured ‘gaining more friends’, ‘enhanced self or life-satisfaction’ and ‘joy in life’. Perceived benefits were particularly high among the less educated and the older students. While students participating in the Older People's Classes were older and included relatively more women, differences between the two models in motives and benefits did not exist or were slight. These results are discussed in the context of new strategies to improve university courses aimed at older students.
  Ageing and Society 10/2010; 30(08):1357 - 1372. · 1.16 Impact Factor
• Article: Measuring well-being among Spanish older adults: development of a simplified version of Ryff's Scales of Psychological Well-being.

  Feliciano Villar, Carme Triadó, Montserrat Celdran, Carme Solé
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  ABSTRACT: Two studies were designed to develop and obtain information about the psychometric properties of a shortened 54-item, Spanish version of Ryff's Scales of Psychological Well-being adapted to older people. In Study 1, 267 older people completed the scales, and data were submitted to a principal components analysis. Then, 22 items were selected and grouped into four components (Self-confidence, Orientation to present, Stress, and Social tension) to form the Simplified Ryff's Well-being Scales. In Study 2, the new scales were administered to 107 older people. While internal consistency estimates were similar to those generally obtained for the 54-item scale, results extracted from a confirmatory factor analysis did not support any factorial model. Although the simplified scales can distinguish between conceptually different approaches to well-being, further studies are needed to obtain estimates of reliability and validity.
  Psychological Reports 08/2010; 107(1):265-80. · 0.44 Impact Factor
• Article: Reasons for Older Adult Participation in University Programs in Spain

  Feliciano Villar, Carme Triadó, Sacramento Pinazo, Montserrat Celdrán, Carme Solé
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  ABSTRACT: This study examined the reasons expressed by older adults for attending a university program in Barcelona (Spain). Results were based on the responses of 36 elders to questions from a semistructured interview. These were (a) reasons for joining a university course and (b) factors that prevent enrolling in that course. Participants mentioned more expressive than instrumental reasons for participating in a university program. Most mentioned barriers to entering university that were lack of interest, lack of self-confidence, health problems, and limited information. These results are discussed in the context of new strategies to improve university courses aimed at the elderly.
  Educational Gerontology 03/2010; 36(3):244-259. · 0.39 Impact Factor
• Article: Contributions of music to aging adults' quality of life.

  Carme Solé, Melissa Mercadal-Brotons, Sofia Gallego, Mariangels Riera
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  ABSTRACT: The purpose of this study was: (a) To evaluate and to compare the impact of three music programs (choir, music appreciation and preventive music therapy sessions) on the quality of life of healthy older adults, and (b) to identify the motivations and the difficulties that seniors encounter when participating in activities of this type, in order to come up with recommendations and strategies for the design of appropriate programs for older adults. A pre-posttest quasi-experimental design without equivalent control group was used in this project. The sample included 83 persons over 65 years of age. The data collection was carried out through an ad hoc questionnaire that included the four aspects of the construct of quality of life (physical health, subjective health, psychological well-being and interpersonal relations), a questionnaire on motivation and another on satisfaction about the program. This questionnaire on quality of life was administered twice: at the beginning of the programs (pretest) and at the end (posttest). The results of this study indicate that the participants perceived improvements in some aspects of their quality of life. In addition, the main reasons which motivate participation in these musical activities are to broaden the social network and to acquire new knowledge. The results are discussed in the light of the challenges of active and satisfactory aging.
  Journal of music therapy 01/2010; 47(3):264-81. · 0.80 Impact Factor
• Article: Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisiae.

  Eva Klopf, Ludmila Paskova, Carme Solé, Gloria Mas, Andriy Petryshyn, Francesc Posas, Ulrike Wintersberger, Gustav Ammerer, Christoph Schüller
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  ABSTRACT: In yeast, environmental stresses provoke sudden and dramatic increases in gene expression at stress-inducible loci. Stress gene transcription is accompanied by the transient eviction of histones from the promoter and the transcribed regions of these genes. We found that mutants defective in subunits of the INO80 complex, as well as in several histone chaperone systems, exhibit extended expression windows that can be correlated with a distinct delay in histone redeposition during adaptation. Surprisingly, Ino80 became associated with the ORFs of stress genes in a stress-specific way, suggesting a direct function in the repression during adaptation. This recruitment required elongation by RNA polymerase (Pol) II but none of the histone modifications that are usually associated with active transcription, such as H3 K4/K36 methylation. A mutant lacking the Asf1-associated H3K56 acetyltransferase Rtt109 or Asf1 itself also showed enhanced stress-induced transcript levels. Genetic data, however, suggest that Asf1 and Rtt109 function in parallel with INO80 to restore histone homeostasis, whereas Spt6 seems to have a function that overlaps that of the chromatin remodeler. Thus, chromatin remodeling by INO80 in cooperation with Spt6 determines the shape of the expression profile under acute stress conditions, possibly by an elongation-dependent mechanism.
  Molecular and cellular biology 08/2009; 29(18):4994-5007. · 6.06 Impact Factor
• Source

  Available from: ucm.es

  Article: Daily activity and life satisfaction in older people living in rural contexts.

  Carme Triadó, Feliciano Villar, Carme Solé, Montserrat Celdrán, Maria José Osuna
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  ABSTRACT: This study is aimed at exploring daily and desired activity patterns in a sample of older people living in a rural context, as well as at examining the effect of some influential factors and their relationships with life satisfaction. Our sample was made of 216 retired people and was recruited from 12 villages from Catalonia and Valencia with populations of less than 1000 inhabitants. Data were gathered by means of an interview that included daily and ideal activities and life satisfaction (by applying the Life Satisfaction Index). Our results show that yesterday's pattern of activities is similar to an ideal pattern, although in the ideal day, our sample allocated more time to social activities and less time to passive activities such as watching TV or resting. In both cases, leisure activities and time spent working seem to play an important role in older people's life. Gender has a remarkable influence on patterns of activity, as women devoted more time to instrumental activities and less time to leisure. In general, differences between yesterday's and ideal activities were not related to life satisfaction.
  The Spanish journal of psychology 06/2009; 12(1):236-45. · 0.74 Impact Factor
• Article: La relación entre abuelos/as y sus nietos/as adolescentes: comparación de perspectivas generacionalesGrandparent-adolescent grandchildren relationship: Comparison of generational perspectives

  Carme Triadó, Feliciano Villar, Sacramento Pinazo, Carme Solé, Julián Montoro, Montserrat Celdrán
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  ABSTRACT: El presente estudio tiene como objetivo examinar la relación entre abuelos/as y sus nietos/as adolescentes comparando ambos puntos de vista. Una muestra de 67 parejas contestó a una serie de instrumentos paralelos que recogían aspectos de su relación (contacto, actividades de ocio, intercambios de apoyo y cercanía) con el otro miembro de la parejas. Los resultados sugieren que los abuelos/as perciben que la relación cambia más a medida que el nieto/a se hace mayor. Las discrepancias encontradas entre ambas generaciones ponen en duda la adecuación a la relación entre abuelos y nietos de la hipótesis del interés intergeneracional, que predice una percepción más optimista de la relación en las generaciones mayores. Nuestros resultados también remarcan la importancia de considerar la comparación entre perspectivas como aspecto relevante para comprender mejor las relaciones intergeneracionales dentro de la familia.The present study is aimed at examining relationship between grandparents and their adolescent grandchildren comparing both points of view. A sample made up of 67 couples answered a series of parallel instruments encompassing different aspects of the relationship (contact, leisure activities, support interchanges and closeness) with the other member of the couple. Results suggest that grandparents perceive the relationships as more changing as grandchildren age. Discrepancies between members of the dyad seem not to follow the intergenerational stake hypothesis, which predicts that older generations hold a more optimistic perception of the relationship. Our results also highlight the importance of taking into account comparisons between perspectives as a key aspect to achieve a deeper understanding of intergenerational relationships inside the family.
  Infancia y Aprendizaje 08/2008; 31(3):385-398. · 0.40 Impact Factor
• Article: Construct validity of Ryff's Scale of Psychological Well-being in Spanish older adults.

  Carme Triadó, Feliciano Villar, Carme Solé, Montserrat Celdrán
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  ABSTRACT: The purpose of this study was to investigate factorial and content validity of the 9-item per dimension Ryff's Scale of Psychological Well-being in a sample of older Spanish adults. The scale is made up of six subscales: Self-acceptance, Environmental mastery, Positive relations with others, Autonomy, Personal growth, and Purpose in life. After translating the scale, it was administered to 422 retired people ages 65 and older. The internal consistency coefficients of the subscales were modest to low, but similar to the ones reported in previous studies. Although correlation profiles of the subscales replicated previous findings and are consistent with a distinction between two types of well-being (eudaimonic and hedonic), results from a second-order principal factor analysis including alternative well-being measures are rather ambiguous. As for the proposed 6-factor structure of the scale, neither exploratory principal component analysis nor confirmatory factor analysis supported clearly this factor structure, with or without second-order latent constructs.
  Psychological Reports 07/2007; 100(3 Pt 2):1151-64. · 0.44 Impact Factor
• Article: [Daily life activity patterns among the elderly: is what they claim to do what they wish to do?].

  Feliciano Villar, Carme Triadó, Carme Solé, Maria José Osuna
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  ABSTRACT: This study is aimed at exploring daily and desired activity patterns in a sample of older people, as well as at examining some influence factors and their relationships to life satisfaction. Our sample was made of 154 retired people living in urban areas and whose age was greater than 60 years old. Data about activities were gathered by means of an interview while life satisfaction scores were obtained by applying LSI scale. Our results show how the pattern of activities that our participants say to have done yesterday is quite similar to an ideal pattern, although in the ideal day time spent with other people is far greater. Factors like gender and economic and educational level have an influence on patters of activity, especially on instrumental and leisure ones. The difference between yesterday and ideal activities was negatively related to life satisfaction. Such a relationship was modest, but reached statistical significance.
  Psicothema 03/2006; 18(1):149-55. · 1.02 Impact Factor