Jong Man Kim

Pusan National University, Tsau-liang-hai, Busan, South Korea

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Publications (70)98.55 Total impact

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    ABSTRACT: This paper proposes a new method to find out optimum overdrive (OD) values through visual inspection only. The method compares different OD values applied on a scrolling pattern. We found that the scrolling pattern with the height of 2° or smaller viewing angle is the best choice to find the optimum OD values. After only three trials performed by users, it is possible to estimate the OD values for all the transitions of the LCDs.
    SID Symposium Digest of Technical Papers. 06/2014; 45(1).
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    ABSTRACT: TiO2 nanofibers (NFs) were fabricated by an electrospinning process and were used as scattering layers in dye-sensitized solar cells (DSSCs). The NF-coated photoanodes of the DSSCs were prepared with a variety of scattering layer thicknesses. The thickness effect of the scattering layer on the double-layered TiO2 nanoparticle (NP)/TiO2 NF structure was investigated through structural, morphological, and optical measurements. In the double-layered photoanode, the TiO2 NP layer plays a major role in dye adsorption and light transmission, and the TiO2 NF scattering layer improves the absorption of visible light due to the light scattering effects. The scattering effect of TiO2 NFs layer was examined by the incident monochromatic photon-to-electron conversion efficiency (IPCE) and UV-Vis spectrometry. The conversion efficiency for the 12 μm-thick photoanode composed of a 2 μm-thick TiO2 NF layer and 10 μm-thick TiO2 NP layer was higher than that of DSSCs with only TiO2 NPs photoanode by approximately 33%.
    Current Applied Physics 01/2014; · 1.81 Impact Factor
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    ABSTRACT: We demonstrated that the size and morphology of an oxidizer have strong effects on the propulsion forces of nano-Al-based propellants. Enhanced propulsion forces could be obtained through the creation and addition of various oxidizer nanoparticles and nanowires in nano-Al-based propellants.
    Journal of Nanoscience and Nanotechnology 10/2013; 13(10):7037-41. · 1.15 Impact Factor
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    ABSTRACT: The purpose of this study was to analyze the survival of patients with biliary atresia (BA) after Kasai operation and liver transplantation (LT) and to analyze the factors affecting survival. Seventy-two patients diagnosed with BA were operated on between April 1995 and December 2009 and retrospectively analyzed. Out of the 72 patients, 59 received Kasai operation and 13 received LT without prior Kasai operation. Twenty-seven patients received LT after Kasai operation. Survival with native liver was 39 % at 10 years. With the application of LT, overall 10-year survival for patients with BA was 94.9 %. Among patients alive with native livers after Kasai operation, 14 patients (58.3 %) have at least one complication associated with biliary cirrhosis and portal hypertension. Age at which Kasai operation was performed (60 days) and postoperative normalization of bilirubin were independent risk factors for survival with the native liver, according to multivariate analysis (HR 2.90, p = 0.033 and HR 9.89, p = 0.002). Survival of BA patients has greatly increased in the era of LT. However, many patients surviving with native livers after Kasai operation continue to have signs of biliary cirrhosis and abnormal liver function.
    Pediatric Surgery International 08/2013; · 1.22 Impact Factor
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    ABSTRACT: ABO-incompatible liver transplantation is usually contraindicated because of the risk of antibody-mediated humoral rejection of the graft. We describe 22 successful cases of patients who had living donor liver transplantation (LDLT) from ABO-incompatible donors. The immunosuppressive protocol consisted of rituximab and plasmapheresis prior to LDLT. Plasmapheresis was planned for up to 2 weeks after LDLT aiming at maintaining levels of anti-ABO titers below 1:32. The median age of recipients was 54 years and the median MELD score was 13. The initial range of isoagglutinin IgM and IgG titers were 1:8 - 1:1024 and 1:2 - 1:1024, respectively. Preoperative isoagglutinin IgM and IgG titers were achieved less than or equal to 1:8 by performing therapeutic plasma exchange (PTE). While the median number of TPE was 4 (range, 2-18) in all patients, it was 4 (range 2-8) in initial low titer group (<1:256) and was 8 (range 6-18) in the high titer group (⩾1:256). There were no statistically significant differences for liver functions tests in the first 2 weeks after transplantation between the groups having high MELD score (⩾20) vs. low MELD score (<20), local graft infusion vs. systemic infusion, or high initial isoagglutinin titer (⩾1:256) vs. low initial isoagglutinin titer (<1:256). Patient and graft survival was 100% and there was no acute humoral rejection in recipients at a mean follow-up of 10 months (range, 3-21). ABO-incompatible LDLT can be safely performed when rituximab and TPE are used, and may be proposed when ABO-compatible donors are not available.
    Journal of Hepatology 08/2013; · 9.86 Impact Factor
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    ABSTRACT: We propose a novel method to drive ultra-large size and high resolution LCD TV with a single-bank data driver scheme without severe image degradation. We could achieve a maximum luminance and uniformity to be 98cd/m2 and 86%, respectively when gray 128 is displayed. This confirms excellent performance because the conventional dual-bank driver scheme achieves the counterparts to be 90cd/m2 and 93%.
    SID Symposium Digest of Technical Papers. 06/2013; 44(1).
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    ABSTRACT: BACKGROUND: Hepatocellular carcinoma (HCC) has a high predilection for portal vein invasion, and the prognosis of HCC with malignant portal vein invasion is extremely poor. The objective of this study was to investigate the outcomes and the prognostic factor of recurrence in HCC patients with malignant portal vein invasion. METHODS: We retrospectively reviewed the clinicopathologic data and outcomes of 83 HCC patients with malignant portal vein invasion and 1,056 patients without portal vein invasion who underwent liver resection. RESULTS: Increased serum alkaline phosphatase (ALP) levels, increased maximum tumor size, and intrahepatic metastasis were predisposing factors for malignant portal vein invasion by multivariate analysis. The median disease-free survival and overall survival of HCC patients with malignant portal vein invasion was 4.5 months and 25 months, respectively. The 1-year, 2-year, and 3-year disease-free survival rates were 30.6%, 26.1%, and 21.2%, respectively, and the overall survival rates for HCC patients with malignant portal vein invasion were 68.6%, 54.2%, and 41.6%, respectively. The initial detection site was the lung in HCC patients with portal vein invasion and the liver in HCC patients without portal vein invasion. C-reactive protein (CRP) was a significant independent predictor of tumor recurrence in HCC with malignant portal vein invasion after surgery. CONCLUSIONS: Increased ALP levels, increased maximum tumor size, and intrahepatic metastasis were independent predictors of malignant portal vein invasion in HCC. CRP level was closely associated with the predisposing factor of tumor recurrence in HCC patients with malignant portal vein invasion after a surgical resection, and lung metastasis was common.
    World Journal of Surgical Oncology 04/2013; 11(1):92. · 1.09 Impact Factor
  • Hepato-gastroenterology 04/2013; 60(128). · 0.77 Impact Factor
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    ABSTRACT: BACKGROUND: The degree of steatosis is an important factor that determines the graft function in the recipient and the recovery of the remnant liver in the living donor. To date, there is no consensus regarding how to assess steatosis among potential living liver donors. We evaluate the prevalence and risk factors for steatosis in living liver donors with normal serum aminotransferase levels and without fatty liver on ultrasonography (US-negative). METHODS: The degree of steatosis was assessed for a total of 492 US-negative living liver donors with normal aminotransferase levels (age 30.1±9.9; male 301 [61.2%]). Total steatosis was defined by adding the degree of macrosteatosis and microsteatosis. RESULTS: No liver donor had a severe degree (≥60%) of macrosteatosis or microsteatosis. A moderate degree (30-59%) of macrosteatosis and microsteatosis was seen in 4 (0.8%) and 26 (5.3%) subjects, respectively. Severe and moderate degrees of total steatosis were seen in 3 (0.6%) and 53 (10.8%) subjects, respectively. Body mass index and serum triglyceride levels were independent factors associated with the moderate or greater degree of total steatosis. CONCLUSIONS: Noninvasive preoperative assessment for liver steatosis (US-negative with normal aminotransferase level) was sufficient to exclude severe macrosteatosis or microsteatosis and moderate macrosteatosis but not sufficient to exclude moderate microsteatosis or total steatosis in living liver donors.
    Transplantation 03/2013; · 3.78 Impact Factor
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    ABSTRACT: BACKGROUND: At the time of transplantation, a recipient's serum is tested against the prospective donor's lymphocytes to identify specific reactivity and to look for a donor-specific crossmatch (CXM). Here, we investigated the relationship between the pretransplantation lymphocytotoxic CXM results and the long-term outcome of liver transplantation at a single center. METHODS: From October 1998 to April 2011, medical records, laboratory data, and pretransplantation lymphocytotoxic CXM results were collected from 1133 consecutive liver transplant recipients. RESULTS: We performed liver transplantations on 80 (7.1%) patients after a true-positive CXM (t+CXM). The t+CXM group exhibited higher initial aminotransferase levels immediately after transplantation compared with a negative CXM group. However, no significant differences in rejection, biliary or vascular complications, viral disease recurrence, or de novo malignancies were found. Although overall graft and patient survival did not differ between the groups, liver-specific graft survival was inferior in the t+CXM group. It was also found that, in 42 (3.7%) recipients, initially positive results converted to final negative results after the elimination of immunoglobulin M autoantibodies. We defined this subpopulation as a false-positive CXM. Significantly decreased posttransplantation aminotransferase levels with a higher incidence of de novo malignancies were observed in this group compared with negative controls. CONCLUSION: Our findings demonstrate that t+CXM transplants show increased aspartate aminotransferase and alanine aminotransferase peak immediately after transplantation, which influences liver-specific graft outcomes. Additionally, the presence of circulating immunoglobulin M autoantibodies against recipients' own antigens may be protective in liver grafts. However, this may be a predisposing factor for de novo malignancies.
    Transplantation 03/2013; · 3.78 Impact Factor
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    ABSTRACT: BACKGROUND: Hepatocellular carcinoma (HCC) <2 cm in diameter has a favorable prognosis. Therefore surgical resection of small HCC is associated with good outcomes. However, the predisposing factors of prognosis following resection of HCC remain ill-defined. The aims of the present study were to identify the clinicopathologic characteristics and outcomes of patients with small HCC and analyze the predisposing factors for tumor recurrence after surgery. METHODS: We retrospectively reviewed 180 patients with small HCC who underwent hepatectomy between 2006 and 2010. Independent predictors of tumor recurrence were identified with Cox regression analysis. RESULTS: The 1-year, 3-year, and 5-year disease-free survival rates and overall survival rates were 83.7, 68.0, 65.3, and 98.9, 96.5, 92.7 %, respectively. Multivariate analysis reported that protein induced by the vitamin K antagonist-II (PIVKA-II) ≥200 mAU/mL, alkaline phosphatase (ALP) ≥80 IU/mL, and microvascular invasion were important predisposing factors for tumor recurrence. Elevated serum PIVKA-II level was associated with microvascular invasion in small HCC, which was a powerful predisposing factor. CONCLUSIONS: Although small HCC is generally associated with a good prognosis, serum PIVKA-II level ≥200 mAU/mL, ALP ≥ 80 IU/L, and microvascular invasion were predisposing factors for tumor recurrence. These factors can be used to stratify patients with respect to recurrence after resection. Elevated PIVKA-II was closely associated with microvascular invasion in small HCC. These data emphasize the importance of PIVKA-II in small HCC.
    World Journal of Surgery 02/2013; · 2.23 Impact Factor
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    ABSTRACT: BACKGROUND: Hepatectomy is the standard treatment for HCC. However, large HCC poses a difficult challenge because of the technical complexity of surgical resection and the fear of postoperative hepatic decompensation. We analyzed the outcome and prognostic factors in patients with large hepatocellular carcinoma (HCC >=10 cm) after surgery. METHODS: We retrospectively investigated the medical records of 91 patients who had undergone hepatectomy between January 2006 and June 2010. A survival analysis was performed utilizing the Kaplan-Meier method and prognostic factors were evaluated using Cox regression analysis. RESULTS: Of the 91 patients evaluated, most tumors were associated with hepatitis B virus (HBV). The median tumor size was 12.3 cm (range, 10 to 21 cm), with microvascular invasion present in most patients. The postoperative mortality rate was 2.2%. The median disease-free survival and overall survival were six months and 41 months. The one-year, two-year, and three-year disease-free survival rates were 33.5%, 29.3%, and 18.8%, respectively. The one-year, two-year, and three-year overall survival rates were 73.9%, 63.7%, and 54.8%, respectively. Of the 89 surviving patients, 69 patients (77.5%) developed HCC recurrence during the mean follow-up period of 23.4 +/- 15.9 months. On multivariate analysis, the statistically significant factors that predicted HCC recurrence were ALP >= 80 IU/mL (P = 0.009) and intrahepatic metastases (P = 0.013). CONCLUSIONS: Our study suggests that preoperative ALP levels (>= 80 IU/L) and intrahepatic metastases could be utilized to monitor and predict recurrence in HCC patients.
    World Journal of Surgical Oncology 02/2013; 11(1):40. · 1.09 Impact Factor
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    ABSTRACT: Pediatric liver transplantation is the standard of care for treatment of liver failure in children. The aim of this study was to identify the characteristics of pediatric liver transplantation in centers located in Korea and determine factors that influence outcomes. This retrospective study was performed using data from between 1988 and 2010 and included all recipients 18 yr old and younger who underwent pediatric liver transplantation in Korea during that period. Our data sources were hospital medical records and the outcome measure was overall patient survival. Univariate and multivariate statistical analyses were undertaken using the Cox proportional hazards model. Five hundred and thirty-four pediatric liver transplantations were performed in 502 children. Median age and average pediatric end-stage liver disease (PELD) score were 20 months and 18 point, respectively. Biliary atresia (57.7%, 308/534) was the most common cause of liver disease. Eighty-two (15.3%) were deceased donor liver transplantations and 454 (84.7%) were living donor liver transplantations. Retransplantation was performed in 32 cases (6%). Overall, 1-, 5-, and 10-yr patient survival rates were 87.8%, 82.2%, and 78.1%, respectively. In multivariate analysis, independent significant predictors of poor patient survival were chronic rejection and retransplantation. This study presents the epidemiologic data for nearly all pediatric liver transplantation in Korea and shows that the independent prognostic factors in patient survival are chronic rejection and retransplantation.
    Journal of Korean medical science 01/2013; 28(1):42-7. · 0.84 Impact Factor
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    ABSTRACT: BACKGROUND: The prognosis of fulminant hepatic failure (FHF) depends on the etiology and reversibility. In this study, we identified the etiological difference of FHF in Korea and analyzed the prognostic factors after liver transplantation (LT) for FHF. METHODS: We retrospectively reviewed 42 patients with FHF who underwent LT from April 1999 to April 2011 at Samsung Medical Center, Seoul, Korea. The patients were categorized into two groups according to the short-term result of LT, and perioperative profiles were compared to identify the short-term poor prognostic factors. RESULTS: Unlike Western countries, there was no paracetamol-related FHF but herbal/folk medicines were the most frequent causes of FHF (26.2%). HAV-related FHF increased significantly and comprised the main portion of FHF with Herbal/folk medicines after 2005. Encephalopathy grade, onset time, pre-transplantation need of renal replacement, and ventilator treatment were significantly different between groups in univariate analysis. In multivariate analysis, pre-transplantation renal replacement treatment and hepatic encephalopathy grade IV were the independent prognostic factors after LT. CONCLUSIONS: The etiologies of FHF in Korea were different compared with Western reports. The requirement of renal replacement treatment and hepatic encephalopathy grade IV were identified as independent poor prognostic factors after LT for FHF in this study.
    Clinical Transplantation 12/2012; · 1.63 Impact Factor
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    ABSTRACT: Massive intraoperative bleeding during liver transplantation often requires large amounts of blood products. The goal of this study was to investigate long-term outcomes of living donor liver transplantation (LDLT) recipients with hepatocellular carcinoma (HCC) who underwent intraoperative use of intraoperative blood salvage (IBS) and leukocyte depletion filter (LDF). In this study, we included 230 LDLT recipients with HCC from two transplantation centers, between February 2002 and December 2007. Group 1 patients (n = 121) underwent intraoperative IBS with LDF and group 2 patients (n = 109) did not. The amount of autotransfused, filtered red blood cells (RBCs) in group 1 was 1590.2 ± 1486.8 ml, which corresponded to 5.9 units of allogenic leukocyte-depleted RBCs saved. The incidences of renal dysfunction, postoperative bleeding, and urinary tract infection in group 2 were higher than in group 1 (P < 0.05). Recurrence-free survival rates for 1, 3, and 5 years were 91.3%, 83.3%, and 83.3%, respectively, in group 1, and 84.6%, 79.0%, and 77.4%, respectively, in group 2 (P = 0.314). IBS using LDF does not increase the risk of cancer recurrence during LDLT for recipients with HCC. Therefore, the use of IBS with LDF appears to be safe for LDLT recipients with HCC.
    Transplant International 11/2012; · 3.16 Impact Factor
  • Journal of Pediatric Surgery 04/2012; 47(4):819-21. · 1.38 Impact Factor
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    ABSTRACT: Reports on the risk factors of peritoneal recurrence (PR) after liver resection for hepatocellular carcinoma are lacking. We examined the risk factors of PR after hepatectomy and the outcome of resected PR at our institution. We retrospectively reviewed the data from 1,222 patients who underwent hepatectomies for hepatocellular carcinoma in Samsung Medical Center from January 2006 to August 2010. We identified patients with PR and studied the risk factors and outcomes of resected PR. The rate of PR was 3.0% (n=36). The mean±SD age of patients was 54.0±10.2 years. Among those with PR, 23 patients (63.9%) had unresectable disease and 13 patients (36.1%) had resectable disease. Multivariate analysis found that tumor size>50 mm, presence of microvascular invasion, bile duct invasion, and positive margins were significant risk factors of PR after liver resection. The median overall survival (OS) for resectable PR was 33.0 (28.0-61.6) months compared to 14.0 (6.8-21.2) months for unresectable PR (P=0.009). Cox regression analysis demonstrated that resected PR [hazard ratio (HR) 0.042, P = 0.001] and interval between hepatectomy and PR (>6 months) (HR 0.195, P=0.016) were positive prognostic factors for OS, while alfa-fetoprotein>200 ng/dl at detection of PR (HR 11.321, P=0.015) and serosal involvement of primary hepatocellular carcinoma (HR 25.616, P=0.007) were negative prognostic factors for OS. We found that tumor size>50 mm, presence of microvascular invasion, bile duct invasion, and positive resection margins were significant risk factors of PR after liver resection. Selected patients with resected PR had significantly better OS.
    Annals of Surgical Oncology 03/2012; 19(7):2246-55. · 4.12 Impact Factor
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    ABSTRACT: Because of the shortage of deceased-donor livers for transplantation, living-donor liver transplantation (LDLT) has become an indispensible treatment strategy for end-stage liver disease. The critical prerequisite for LDLT is the maximal safety of healthy donors. From June 1996 to November 2010, a total of 827 completed donor hepatectomies were performed in our center. We analyzed donor morbidity associated with LDLT. There was no donor mortality. No complications were observed in 744 (90.0%) donors, and 83 (10.0%) donors experienced complications. Wound complications were most common, occurring in 48 (5.8%) patients. According to a modified Clavien classification, grade I, grade II, grade IIIa, and grade IIIb complications were experienced in 56 (67.5%), 2 (2.4%), 15 (18.1%), and 10 (12.0%) donors, respectively. Surgical or interventional management was successful in all grade IIIa and grade IIIb donors. The incidence of biliary complications was significantly higher in younger donors. Donor morbidity did not decrease below the attained level even after time had passed. This study demonstrates the safety of donor hepatectomy. Complications were relatively minor and easily controlled. The incidence of biliary complications and donor age was inversely correlated. The procedural experience of the surgeons was not associated with the donor complication rate.
    Transplantation 02/2012; 93(9):942-8. · 3.78 Impact Factor
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    ABSTRACT: An equivalent islet number (EIN) greater than 300,000 is necessary for islet cell transplantation for a recipient who weighs about 60 kg. The aim of this study is to identify factors that affect isolation outcome. The most significant independent predictor for successful islet isolation from deceased donors was low international normalized ratio (INR).
    Diabetes research and clinical practice 11/2011; 95(3):e45-8. · 2.74 Impact Factor
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    Jong Man Kim, Sung Joo Kim
    08/2011; , ISBN: 978-953-307-807-6

Publication Stats

282 Citations
98.55 Total Impact Points

Institutions

  • 2011–2014
    • Pusan National University
      • College of Nanoscience and Nanotechnology
      Tsau-liang-hai, Busan, South Korea
    • Ulsan University Hospital
      Urusan, Ulsan, South Korea
  • 2011–2013
    • Kyung Hee University
      • • Department of Information Display
      • • Advanced Display Research Center
      Sŏul, Seoul, South Korea
  • 2010–2013
    • Sungkyunkwan University
      • Department of Surgery
      Sŏul, Seoul, South Korea
  • 2003–2008
    • Hanyang University
      • • Division of Chemical Engineering and Bioengineering
      • • Major in Biochemistry & Molecular Biology
      Ansan, Gyeonggi, South Korea
  • 2002–2006
    • Samsung Advanced Institute of Technology
      Usan-ri, Gyeonggi Province, South Korea