Young Hyo Kim

Inha University Hospital, Sinhyeon, South Gyeongsang, South Korea

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Publications (28)24.49 Total impact

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    ABSTRACT: To evaluate the antiallergic effects of oral benzaldehyde in a murine model of allergic asthma and rhinitis, we divided 20 female BALB/c mice aged 8–10 weeks into nonallergic (intraperitoneally sensitized and intranasally challenged to normal saline), allergic (intraperitoneally sensitized and intranasally challenged to ovalbumin), and 200- and 400-mg/kg benzaldehyde (allergic but treated) groups. The number of nose-scratching events in 10 min, levels of total and ovalbumin-specific IgE in serum, differential counts of inflammatory cells in bronchoalveolar lavage (BAL) fluid, titers of Th2 cytokines (IL-4, IL-5, IL-13) in BAL fluid, histopathologic findings of lung and nasal tissues, and expressions of proteins involved in apoptosis (Bcl-2, Bax, caspase-3), inflammation (COX-2), antioxidation (extracellular SOD, HO-1), and hypoxia (HIF-1α, VEGF) in lung tissue were evaluated. The treated mice had significantly fewer nose-scratching events, less inflammatory cell infiltration in lung and nasal tissues, and lower HIF-1α and VEGF expressions in lung tissue than the allergic group. The number of eosinophils and neutrophils and Th2 cytokine titers in BAL fluid significantly decreased after the treatment (P < 0.05). These results imply that oral benzaldehyde exerts antiallergic effects in murine allergic asthma and rhinitis, possibly through inhibition of HIF-1α and VEGF.
    International Immunopharmacology. 01/2014;
  • Young Hyo Kim, Tae Young Jang
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    ABSTRACT: Experience with the use of porous high-density polyethylene (PHDPE) for reconstruction of the nasal framework has been limited.
    01/2014; 22(1):14-7.
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    ABSTRACT: Objective Disagreement between results of skin prick test (SPT) and nasal provocation tests (NPT) causes difficulty in differential diagnosis of allergic rhinitis (AR) and nonallergic rhinitis (NAR). We hypothesized this discrepancy could be due to the nonspecific hyper-reactivity (NHR) and localized allergy of the nasal cavity.Study DesignProspective pilot.SettingAcademic tertiary rhinologic practice.Subjects and Methods Sixty patients with AR and 62 with NAR were enrolled. We categorized patients according to results of SPT and NPT. We compared: (1) the clinical characteristics and severity of the disease, (2) change of minimal cross-sectional area (MCA) and total nasal volume (TNV) after normal saline (NS) challenge, and (3) change of nasal symptoms and acoustic parameters after intranasal house dust mite (HDM) challenge between groups.ResultsPatients in groups A (SPT[+]/NPT[+]) and C (SPT[-]/NPT[+]) complained of more persistent discomfort than those in groups B (SPT[+]/NPT[-]) and D (SPT[-]/NPT[-]). The proportion of moderate to severe symptoms was significantly higher in groups A, B, and C compared to group D. After NS challenge, MCA/TNV showed a significantly greater decrease in groups A (MCA: 27.6% ± 21.3%, TNV: 24.6% ± 16.4%) and C (MCA: 31.2% ± 24.0%, TNV: 24.1% ± 23.4%) compared to groups B (MCA: 0.1% ± 13.2%, TNV: 3.9% ± 13.5%) and D (MCA: 2.1% ± 12.1%, TNV: 2.0% ± 17.2%) (P < .05). After HDM challenge, groups A/B showed a greater decrease in MCA (Group A: 62.4% ± 16.1%, Group B: 6.4% ± 11.3%) compared to groups C/D (Group C: 45.5% ± 14.4%, Group D: -3.0% ± 9.5%).ConclusionNHR and/or localized allergy should be considered in patients with rhinitis whose SPT and NPT results are not in agreement.
    Otolaryngology Head and Neck Surgery 12/2013; · 1.73 Impact Factor
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    ABSTRACT: Epileptic nystagmus is defined as a quick, repetitive jerky movement of the eyeball associated with seizure activity. In cases of epileptic nystagmus associated with ictal discharge from multiple brain areas, localization of the exact epileptogenic zone could be extremely difficult. In a nine-year-old patient with epileptic nystagmus and vertigo associated with bilateral temporal and frontal lobe epilepsy, we could infer the epileptic focus by interpreting the patient's clinical picture, characteristics of nystagmus, and findings of electroencephalography.
    Clinical and Experimental Otorhinolaryngology 12/2013; 6(4):259-62. · 0.88 Impact Factor
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    ABSTRACT: BACKGROUND: Sialic acid-binding Ig-like lectin-F (Siglec-F) in mice and its functional paralog Siglec-8 in humans are transmembrane receptors that play a role in the apoptosis of eosinophils. We aimed to evaluate the therapeutic potential of anti-Siglec-F antibodies in a murine model of allergic rhinitis. METHODS: Twenty-eight BALB/c mice were used. In group A (control group, n = 7), mice were sensitized and challenged with saline. In group B (ovalbumin [OVA] challenge group, n = 7), OVA was used for i.p. sensitization and intranasal challenge. Mice in group C (control IgG group, n = 7) or those in group D (anti-Siglec-F group, n = 7) had been given rabbit control IgG or anti-Siglec-F antibody injections, respectively. We assessed the number of nose-scratching events; serum total/OVA-specific IgE; the number of eosinophils, neutrophils, and lymphocytes in bronchoalveolar lavage (BAL) fluid; histopathological changes in nasal cavity tissues; and the levels of IL-4, IL-5, and IL-13 in BAL fluid. RESULTS: Mice in group D had significantly less nose scratching. Serum total and OVA-specific IgE were not significantly changed. The number of eosinophils in BAL fluid and in the lamina propria of the nasal cavity mucosa was significantly decreased with anti-Siglec-F antibody treatment. The levels of Th2 cytokines such as IL-4, IL-5, and IL-13 were also significantly decreased with anti-Siglec-F antibody treatment. CONCLUSION: Anti-Siglec-F antibody has beneficial effects in a mouse model of experimental allergic rhinitis.
    American Journal of Rhinology and Allergy 05/2013; 27(3):187-191.
  • Young Hyo Kim, Tae Young Jang
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    ABSTRACT: Nasal provocation tests (NPTs) are useful for evaluation of patients with allergic rhinitis. The cold dry air (CDA) provocation test is useful for evaluation of patients with nonspecific nasal hyperreactivity (NHR). This study aimed to determine whether the NPT or CDA provocation would be more useful for patients with different clinical pictures. We evaluated changes in nasal symptoms (visual analog scale [VAS]) and acoustic parameters after NPT or CDA provocation in healthy volunteers (group A, n = 27), patients with allergic rhinitis (group B, n = 20), and subjects with nonallergic rhinitis (group C, n = 26). According to their subjective cold hyperresponsiveness (SCH), we compared changes in VAS and acoustic parameters after each protocol. The correlation between results of the skin-prick test (SPT) and changes in VAS after each protocol was analyzed. Finally, we performed an analysis of correlation between NPT and CDA provocation. After NPT, group B showed a larger change in VAS for rhinorrhea, sneezing, and itching (p < 0.01). After CDA challenge, the change in VAS for nasal obstruction was larger in group C (p < 0.05). Changes in acoustic parameters were larger in groups B and C after NPT (p < 0.01). After CDA challenge, the SCH(+) group (n = 49) showed a larger decrease of acoustic parameters than the SCH(-) group (n = 24; p < 0.01). Significant correlation was observed between the size of SPT and degree of change in VAS after NPT. No significant correlation was observed between NPT and CDA. CDA could be an adjunct tool for evaluating NHR in patients with self-reported SCH.
    American Journal of Rhinology and Allergy 03/2013; 27(2):113-7.
  • Young Hyo Kim, Tae Young Jang
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    ABSTRACT: OBJECTIVE: We evaluated the effect of patients' age and duration of allergic rhinitis on nonspecific nasal hyper-reactivity (NHR) using cold dry air (CDA) provocation. METHODS: In 156 patients of various ages with allergic rhinitis and different symptom duration, we evaluated the change of symptoms, the subjective cold hyper-responsiveness (SCH) grade, the change of acoustic parameters such as total nasal volume (TNV) and minimal cross-sectional area (MCA), and the amount of rhinorrhea before and after CDA provocation. RESULTS: Patients in different age or duration groups did not show significant differences in the change of each nasal symptom. SCH grade 2 or 3 was more frequently observed in patients older than 30 years (p=0.018). There was a significant correlation between the age of the patients and the SCH grade (R=0.184, p=0.022). Patients with >10 years of duration reported higher SCH grade (p=0.022). There was a significant correlation between the duration of disease and SCH grade (R=0.284, p<0.001). However, there were no significant differences in the change of TNV and MCA, and the amount of rhinorrhea after CDA provocation between different age and duration groups. CONCLUSION: SCH grade reflects the age- and duration-related increase of NHR. Further studies to elucidate the pathophysiologic mechanisms are needed in the future.
    Auris, nasus, larynx 08/2012; · 0.58 Impact Factor
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    ABSTRACT: Interleukin (IL)-33, which mediates the T(h)2 allergic pathway, may play a key role in allergic airway inflammation. This study was conducted to evaluate the therapeutic potential of anti-IL-33 antibody for treatment of allergic inflammation of the lower airway in a murine model. Twenty-four BALB/c mice were used in this study. Saline was used for sensitization and challenge of mice in Group A (control group, n = 6). Mice in Group B (ovalbumin (OVA) group, n = 6) received intraperitoneal (ip) and intranasal OVA challenge. In Group C (control IgG group, n = 6), mice received ip injection with control IgG prior to OVA challenge. Mice in Group D (anti-IL-33 group, n = 6) received an ip injection of anti-IL-33 prior to challenge. Measurements of serum total and OVA-specific IgE and the number of eosinophils, neutrophils, and lymphocytes in bronchoalveolar lavage (BAL) fluid were performed. We performed histopathologic examination to evaluate the degree of eosinophilic infiltration in lung tissue. Airway hyperreactivity was measured according to change of enhanced pause (Penh). A significant decrease in serum total and OVA-specific IgE and the number of eosinophils and neutrophils in BAL fluid was observed in Group D, compared with Group B or Group C (p < .05). In Group D, treatment with anti-IL-33 resulted in a significant decrease in eosinophilic infiltration in lung tissue, compared with Group B and Group C (p < .05). Degree of airway hyperreactivity, measured by Penh, showed a significant decrease in the anti-IL-33 treatment group, compared with the OVA group or the control IgG treatment group (p < .01, at 50 mg/mL of methacholine). Anti-IL-33 has therapeutic potential for treatment of allergic inflammation of the lower airway.
    Journal of Asthma 07/2012; 49(7):738-43. · 1.85 Impact Factor
  • Young Hyo Kim, Tae Young Jang
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    ABSTRACT: Abstract Conclusion: Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). Objective: We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured by cold dry air (CDA) provocation and acoustic rhinometry. Methods: A total of 156 patients with allergic or non-allergic rhinitis were classified into three groups according to the decrease of minimal cross-sectional area (MCA) after CDA provocation (group A: n = 40, MCA decrease >60%; group B: n = 29, MCA decrease 30-60%; group C: n = 87, MCA decrease <29%). Symptom scores using the visual analog scale (VAS) were obtained before and after CDA provocation. Changes of VAS were compared between groups. The amount of rhinorrhea was measured after CDA provocation. Results: VAS scores for nasal obstruction, rhinorrhea, and sneezing were significantly higher in groups A and B than in group C before and after CDA provocation. Change of nasal obstruction and rhinorrhea was significantly larger in group A compared with group B or C. There were also significant differences in the amount of rhinorrhea between groups. All these parameters significantly correlated with the change of MCA values after CDA provocation.
    Acta oto-laryngologica 06/2012; 132(10):1095-101. · 0.98 Impact Factor
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    ABSTRACT: Middle ear adenoma is a rare disease that arises from the mucosa of the middle ear. Only a few cases of associated facial nerve paralysis have been reported. Facial nerve involvement is most likely related to nerve compression rather than tumor invasion of the nerve. We describe a case of a huge middle ear adenoma in a 63-year-old man. He presented with a 1-month history of right-sided otalgia, otorrhea, and facial palsy; he also had a 10-year history of right-sided hearing loss. A tympanomastoidectomy was performed. Intraoperatively, the tumor was found to fill the middle ear cavity as well as the entire diameter of the external auditory canal. The tumor had eroded the wall of the facial canal at the second genu, and it was tightly adherent to the epineurium. Focal inflammation around the tumor was observed at the exposed facial nerve. The tumor was removed and the facial nerve was decompressed. Immediately after surgery, the patient's aural symptoms resolved. The final pathology evaluation established the diagnosis of a middle ear adenoma. At the 3-year follow-up, the ear cavity was completely healed and facial nerve function was improved.
    Ear, nose, & throat journal 06/2012; 91(6):E11-4. · 1.03 Impact Factor
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    ABSTRACT: There is still no study involving the immunologic properties of local allergic rhinitis (LAR). We aimed to determine the immunologic profile of patients with LAR by analyzing cytokines in the serum and nasal secretions and correlated the results with clinical characteristics. Ten healthy volunteers (group A), nine patients with allergic rhinitis (group B), and seven patients with LAR (group C) were enrolled. Changes in nasal symptoms, total nasal volume (TNV), and minimal cross-sectional area (MCA) were compared. We performed a Quantibody array for interleukin (IL)-4, IL-13, IL-3, IL-5, granulocyte-macrophage colony-stimulating factor, stem cell factor, IL-10, and transforming growth factor β (TGF-β) using serum and nasal secretions. Patients in group C had more aggravated rhinorrhea and itching than patients in group B (p < .05). The change in TNV and MCA was greater in groups B and C than in group A (p < .01). The serum concentration of IL-10 in group C was higher than in group A or B (p < .001). The concentration of IL-13, IL-5, IL-10, and TGF-β in group C was higher than in group A or B in the nasal secretions (p < .001). Patients with LAR have similar symptoms, similar changes in TNV and MCA, and a similar profile of cytokine production and nasal secretions than those with allergic rhinitis. More prominent immunomodulating properties of LAR patients could in part explain the absence of systemic allergic responses.
    Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 02/2012; 41(1):51-7. · 0.71 Impact Factor
  • Young Hyo Kim, Tae Young Jang
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    ABSTRACT: There is still no study about the correlation between the symptom score and the reactivity to cold dry air (CDA). The authors developed a subjective cold hyperresponsiveness (SCH) scale for CDA and we evaluated its usefulness by comparing the changes of the symptom score and the acoustic parameters between different SCH groups and analyzing the correlation between the SCH scale and other parameters. One hundred fifty-two patients were classified according to their SCH scale. The symptom score by the visual analog scale (VAS), the total nasal volume (TNV), and the minimal cross-sectional area (MCA) by acoustic rhinometry were obtained before and after CDA provocation. Changes of these values were compared between groups and an analysis was performed for the correlation between SCH scale and change of the VAS, TNV, or MCA. The patients with SCH grade 2 or 3 had a greater change of the VAS scores for nasal obstruction and rhinorrhea. The patients with SCH grade 2 or 3 had a greater change of the TNV (grade 0, 26.1 ± 17.2%; grade 1, 33.3 ± 26.5%, versus grade 2, 44.2 ± 30.0%; grade 3, 61.6 ± 40.0%; p < 0.05) and MCA (grade 0, 23.0 ± 25.3%; grade 1, 35.7 ± 51.1%, versus grade 2, 61.2 ± 72.4%; grade 3, 80.5 ± 56.4%; p < 0.05). Significant correlation existed between the SCH scale and changes in the TNV or MCA. We developed the SCH scale and proved its usefulness for evaluating nonspecific hyperreactivity.
    American Journal of Rhinology and Allergy 01/2012; 26(1):45-8.
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    ABSTRACT: Objective. Little is known concerning the role of benign paroxysmal positional vertigo (BPPV) as a prognostic factor for sudden sensorineural hearing loss (SSNHL). The purpose of this study is to analyze the hearing recovery in patients who have SSNHL with BPPV compared with those who have SSNHL without BPPV. The study also documented the relative incidence of each semicircular canal involvement.Study Design. Case-control study.Setting. Academic tertiary otologic practice.Subjects and Methods. Ninety patients diagnosed with SSNHL with vertigo were enrolled. Clinical characteristics such as gender, age, and pure tone audiogram threshold were compared between group A (SSNHL with BPPV, n = 17) and group B (SSNHL without BPPV, n = 73). The frequency of each canal involvement was compared between group A and another 111 patients with BPPV only (group C). The proportion of patients with hearing recovery was compared between patients with or without BPPV, and between those with or without canal paresis.Results. Patients in group A did not display significant differences in the sex ratio, mean age, or initial results of pure tone audiogram threshold compared with those in group B. Most patients with SSNHL with BPPV had lateral canal canalithiasis (64.7%). The presence of BPPV had no influence on the recovery of hearing.Conclusions. The clinical characteristics of patients with SSNHL with BPPV were not different from those with SSNHL without BPPV. The lateral canal was the most frequently involved, and the presence or absence of BPPV had no dramatic impact on the outcome of SSNHL.
    Otolaryngology Head and Neck Surgery 12/2011; · 1.73 Impact Factor
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    ABSTRACT: Intravestibular lipoma (IVL) and intravestibular schwannoma (IVS) are rare tumors occupying the intravestibular space. Patients with IVL or IVS complain of hearing impairment, tinnitus or recurrent rotatory vertigo. Therefore, the clinical practitioner could misdiagnose them as sudden sensorineural hearing loss or Meniere's disease. Since delayed diagnosis and treatment could lead to more severe and refractory symptoms, clinicians should have a high index of suspicion for early diagnosis. Recent advancements in imaging diagnostic tools such as computed tomography and magnetic resonance imaging have facilitated the correct diagnosis of these intravestibular tumors without surgical removal. Presently, we report two different kinds of intravestibular tumors of lipoma and schwannoma which manifest different clinical course and treatment strategies.
    Auris, nasus, larynx 11/2011; 39(4):431-3. · 0.58 Impact Factor
  • Young Hyo Kim, Beom Joon Kim, Tae Young Jang
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    ABSTRACT: Juvenile angiofibroma, nasopharyngeal carcinoma (NPC) and lymphoepithelial carcinoma of the nasal cavity (LEC NC) all could be found as a hyper-vascular mass in the nasopharynx area. Performing biopsy for histopathologic confirmation is necessary in the case of NPC or LEC NC but could be fatal in the case of angiofibroma. In our case, a 21-year-old male who was suffering from unilateral nasal stuffiness and frequent epistaxis had a mass with an easily bleeding tendency in his right nasal cavity. Juvenile angiofibroma was suspected by clinical and radiologic examinations. We performed preoperative angiography and the feeding vessel from the right internal maxillary artery was obliterated with polyvinyl alcohol nanoparticle. The mass was completely removed endoscopically, and there was profound hemorrhage in spite of the preoperative embolization. The mass turned out to be LEC NC by postoperative histopathologic examination. To avoid this misdiagnosis, the authors suggest that we should perform biopsy under rigid endoscopy 24h after angiographic embolization. If the result of frozen biopsy is juvenile angiofibroma, we could perform surgery another 24h later. If the result is nasopharyngeal carcinoma or LEC NC, we could avoid unnecessary surgical removal and perform radiotherapy. In terms of treatment strategies, we suggest endoscopic removal of gross tumor and postoperative combination of chemoradiotherapy as the more curative regimen with less complications related with radiotherapy.
    Auris, nasus, larynx 11/2011; 39(5):519-22. · 0.58 Impact Factor
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    ABSTRACT: Evaluate the effect of septoplasty on the clinical course of allergic rhinitis by comparing (1) symptom change using the Visual Analogue Scale (VAS), (2) change of the medication score, and (3) improvement of the quality of life using a questionnaire. Prospective pilot. Academic tertiary rhinological practice. Sixty-two patients who had undergone septoplasty and turbinoplasty for septal deviation and allergic rhinitis were enrolled in group A. Twenty-six patients who had undergone only turbinoplasty for allergic rhinitis were enrolled in group B. The VAS score, the Average Rescue Medication Score (ARMS), and the Rhinasthma Questionnaire for the quality of life were all obtained from each patient. These parameters were compared before and after the surgery and between the groups. Both groups showed significant improvement of the VAS score (P < .001). When the change of VAS was compared between groups, there was a significant difference in group A only for nasal obstruction (P = .047). Comparison of the ARMS between groups showed significant improvement in both groups after the surgery (P < .01). However, there were no differences between the groups. The Rhinasthma score of group A was significantly lowered after the surgery (56.4 ± 13.2 to 34.1 ± 12.3, P < .001). The Rhinasthma score of group A was significantly lower than that of group B after the surgery (P = .004). This is the first research about the potential effect of septoplasty on the clinical course of allergic rhinitis. Further studies are needed to elucidate the mechanisms underlying these effects.
    Otolaryngology Head and Neck Surgery 09/2011; 145(6):910-4. · 1.73 Impact Factor
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    ABSTRACT: There was no significant difference in the postoperative outcomes between different surgical options for treating chronic maxillary sinusitis (CMS). We aimed to compare the improvement in symptoms, and changes in endoscopic and CT grade in patients undergoing different surgical management of the maxillary sinus ostium. In 32 patients (group A), the pathologic mucosa was radically removed with a power microdebrider. In 28 patients (group B), only part of the pathologic mucosa was removed; gross pathologic lesions were left in situ. In 38 patients (group C), only enlargement of the maxillary ostium was performed. Pre- and postoperative changes in symptoms, endoscopic polyp grade, and Lund-Mackay CT score were compared between groups. In all groups, the symptoms were significantly improved after 1 month and throughout the follow-up period. Patients in groups A and B had meaningful improvement of the endoscopic polyp grade 1 month after surgery. The endoscopic grade of patients in group C at 1 and 3 months after surgery was not significantly different from the preoperative grade; however, there was a meaningful difference after 6 months. At 12 months after surgery, all groups had a significant decrease in the CT score (p < 0.01); however, there was no difference between groups.
    Acta oto-laryngologica 09/2011; 131(9):1002-7. · 0.98 Impact Factor
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    ABSTRACT: CONCLUSION. The recurrence rate of vertigo due to any cause in patients with vestibular neuritis (VN) was about 26.0% in our study. No clinical characteristics were significantly associated with recurrences. We aimed to: 1) determine the prevalence of recurrent VN; 2) compare the clinical characteristics and epidemiologic factors of patients with non-recurrent and recurrent VN; and 3) determine the prevalence of benign paroxysmal positional vertigo (BPPV) in patients with VN. In 131 patients diagnosed as having VN (68 males, aged 49.8 ± 14.9 years and 63 females, aged 57.5 ± 12.5 years), a retrospective chart review and telephone survey about the recurrent vertigo were performed. Vestibular function testing, inner ear magnetic resonance imaging (MRI), and pure tone audiograms were performed on every patient. Vestibular function testing was repeated in patients with recurrences. Fourteen of 131 patients (10.7%) had recurrent VN. The subjective intensity of recurrent VN was less than the first attack. There were no significant differences in clinical characteristics such as accompanying headache or preceding respiratory infection and in epidemiologic risk factors between patients with recurrent and non-recurrent VN. Twenty of 131 patients (15.3%) experienced BPPV during the follow-up period.
    Acta oto-laryngologica 07/2011; 131(11):1172-7. · 0.98 Impact Factor
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    ABSTRACT: There are few studies on the ischemic necrosis and apoptosis of septal cartilage after using bilateral spreader grafts in rhinoplasty. We attempted to evaluate structural changes to the septal cartilage after using the bilateral spreader graft and herein propose possible involved mechanisms observed by histopathologic examination, the apoptosis index using the TUNEL assay, and ultrastructural examination using an electron microscope. Septal cartilage between bilateral spreader grafts (group A, n  =  12), cartilage beside unilateral spreader grafts (group B, n  =  12), and normal septal cartilage (group C, n  =  12) were obtained from 36 patients who had revision rhinoplasty because of minor cosmetic dissatisfaction. We investigated the histopathologic appearance via hematoxylin-eosin staining. Then, using the TUNEL assay, we determined the apoptosis index. Finally, we studied cell morphology under a transmission electron microscope. Although the thickness of septal cartilage was not significantly different between groups, the signs of ischemic necrosis were more prominent in group A. The apoptosis index was significantly higher in group A than in group B or C (p < .05). We observed evidence of cellular injury also by electron microscope examination. The survival of septal cartilage could be affected by bilateral spreader grafts through the mechanism of ischemic necrosis and apoptosis.
    Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 06/2011; 40(3):244-8. · 0.71 Impact Factor
  • Young Hyo Kim, Beom Joon Kim, Tae Young Jang
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    ABSTRACT: In this study, 29 patients with porous high-density polyethylene (group A) and 29 patients with septal cartilage (group B) were enrolled for either spreader or extended septal graft. By questionnaire or telephone survey, the authors evaluated patients' cosmetic satisfaction and complications. The authors also used postoperative photographs to evaluate cosmetic results. For the functional analysis, the change of visual analog scale of nasal obstruction and change of minimal cross-sectional area using acoustic rhinometry were compared. Of 29 patients in group A, 27 were totally satisfied with the results. There was no complication except for 2 cases of extrusion during 5.3 ± 1.8 years. The patients in group A showed more decrease of nasal obstruction by visual analog scale and more improvement of minimal cross-sectional area as compared with those in group B. Therefore, porous high-density polyethylene is an ideal alloplastic material for spreader or extended septal graft in rhinoplasty in both cosmetic and functional aspects. And it is also safe and stable over a long-term period.
    Annals of plastic surgery 02/2011; 67(5):464-8. · 1.29 Impact Factor

Publication Stats

46 Citations
24.49 Total Impact Points

Institutions

  • 2008–2014
    • Inha University Hospital
      Sinhyeon, South Gyeongsang, South Korea
  • 2008–2011
    • Inha University
      • Department of Otorhinolaryngology-Head and Neck Surgery
      Seoul, Seoul, South Korea