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ABSTRACT: To evaluate the effect of depressing the press and the technical possibility of creating a percutaneous retroperitoneal splenorenal shunts (PRESS) by means of treating with swine with portal hypertension.
There were five normal microswine, all of which underwent portal vein embolization with polyvinyl alcohol (PVA) particles to create the model of portal hypertension. After the successful creation of the model with portal hypertension, PRESS were placed to depress the portal venous press, placing covered-stents to connect the left renal vein and the splenic vein. The variance of relative venous press was observed. Splenic venogram was taked after the PRESS to observe the condition of blood flow in the vein and stents.
Acute portal hypertension were created successfully in the five animals, then PRESS were placed. One animal died during the operation (died of overdose of anesthesia), stent placement were successfully completed in the other four animals. The splenic venogram revealed good flow from the splenic vein to the left renal vein through the shunt track. After the PRESS, the portal venous and the splenic press press descended, and the left renal press elevated.
Creation of a PRESS for swine with portal hypertension is technically possible, and further experimental studies of its safety are warranted.
Zhonghua yi xue za zhi 05/2010; 90(17):1216-9.
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ABSTRACT: Since the 1980s, various approaches to interventional therapy have been developed, with the development and achievement of medical imaging technology. This study aimed to evaluate the effectiveness of comprehensive sequential interventional therapy especially personal therapeutic plan in 53 radical cure patients with hepatocellular carcinoma (HCC).
From January 2003 to January 2005, a total of 203 patients with HCC received sequential interventional treatment in our hospital. Fifty-three patients achieved radical cure outcomes. Those patients were treated with transcatheter arterial chemoembolization (TACE), radiofrequency ablation (RFA), percutaneous ethanol injection (PEI), or high intensity focused ultrasound (HIFU), sequentially and in combination depending on their clinical and pathological features. PET-CT was used to evaluate, assess, and guide treatment.
Based on the imaging and serological data, all the patients had a personal therapeutic plan. The longest follow-up time was 24 months, the shortest was 6 months, and mean survival time was 16.5 months.
Comprehensive sequential interventional therapy especially personal therapeutic plan for HCC play roles in interventional treatment of HCC in middle or advanced stage.
Chinese medical journal 10/2009; 122(19):2292-8. · 0.86 Impact Factor
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ABSTRACT: To explore the clinical value of CT guided radio frequency ablation in the treatment of pelvis tumor.
11 males and 8 females ranging from 25 to 49 years old (average 37) were enrolled in this study, all the 19 patients were suffering from pelvis tumor including giant cell tumor of bone (2/19), Ewing's sarcoma (2/19), malignant fibrous histiocytoma (3/19) and metastatic diseases (12/19). The average diameter of the lesions were 6.2 cm. The predominant clinical symptom of the patients was pain in the local region. All the patients were treated by CT guided radio frequency ablation. Single pole or multiple poles radio frequency ablation device was used according to the characteristics of the tumor tissue. Time of therapy was 5-15 min. Superposition was performed if necessary.
All the patients received PET-CT scan or enhanced CT scan 1 month after the treatment, CR, PR was seen in 10 and 7 cases respectively. Total pain relief was seen in 10 patients, partial pain relief was seen in 8 patients, and gently pain relief was seen in 1 patient.
CT guided CT guided radio frequency ablation is an effective methods in the treatment of pelvis tumor.
Zhonghua yi xue za zhi 08/2009; 89(29):2046-9.
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Chinese medical journal 12/2008; 121(22):2353-6. · 0.86 Impact Factor
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ABSTRACT: To evaluate the therapeutic effect of CT-guided high frequency-induced thermotherapy (HiTT) for intrahepatic cholangiocarcinoma.
Seventeen patients of intrahepatic cholangiocarcinoma with 21 lesions underwent comprehensive treatment with HiTT as the principle approach. As to the patients with obstructive jaundice, percutaneous trans-hepatic cholangial drainage (PTCD) or bile duct endoprosthesis placement was performed first to improve the liver function, then HiTT was performed; and patients without obstructive jaundice underwent CT-guided HiTT directly, 1-2 weeks later, chemotherapy was given for 4 - 6 courses.
CT scan 1 week after HiTT showed a short-term achievement rate of 100% (17/17), and the single puncture in situ ablation rate was 76.1% (16/21). The average life span in the near future was 13.5 months. The adverse effects included topo-bleeding, pain after procedure, liver function damage, defervescence, etc. All the patients recovered after symptomatic treatment.
The clinical value of CT-guided HiTT for intrahepatic cholangiocarcinoma is obvious.
Zhonghua yi xue za zhi 08/2008; 88(25):1759-62.
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ABSTRACT: To explore the clinical value of CT guided 125I seeds implantation in the treatment of local recurrent rectal cancer after surgery resection.
Twenty-one patients with local recurrent rectal cancer after surgery, 12 males and 9 females, aged 47 (35-69), with the longest diameter of 4. 2 cm (3.4 - 6.4 cm), were treated by CT guided 125I radioactive seeds implantation according to treatment planning system (TPS) or Halarism's experienced function: mCi = Da x 5. Totally, 506 seeds, 24.1 for one patient on average, were implanted. All the patients received PET-CT scan 3 months after the treatment and were followed up for 12.5 months (7-22 months).
Complete remission, partial remission, and no change were seen in 16, 3, and 2 patients respectively. All patients survived.
CT guided 125I seeds implantation is an effective methods in the treatment of local recurrent rectal cancer after surgery resection.
Zhonghua yi xue za zhi 06/2008; 88(19):1335-8.
