Chun-ling Wang

Tianjin Medical University, T’ien-ching-shih, Tianjin Shi, China

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Publications (30)11.86 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: To detect the changes of Osterix (Osx) mRNA and protein expression in human periodontal ligament cells (HPDLCs) induced by recombinant human bone morphogenetic protein-2 (rhBMP-2), and examine the role of BMP-2 and Osx during the osteogenic differentiation of HPDLCs. HPDLCs were isolated and cultured in vitro with explant method. Cells at passage 3 were cultured in DMEM with rhBMP-2 at different concentrations (50, 100, 150, 200, 250, 300, 400, and 600 µg/L) for different times (2, 3, 5, 7, 10, 14 and 21 days). Then the expressions of Osx mRNA and protein were measured by real-time reverse transcription (RT)-PCR and Western blotting respectively. Cells were treated with 10 µmol/L SB203580 (p38 inhibitor) to inhibit p38 phosphorylation induced by rhBMP-2. The mineralization nodules formation and the expressions of phosphorylated p38 and Osx mRNA were detected respectively. During the culture of rhBMP-2, the expression of Osx mRNA significantly increased. Initially Osx protein had a low expression and then increased in a time-dependent manner followed by the production of bone-like nodules in HPDLCs. Under the effect of SB203580, the up-regulation of phosphorylated p38 expression induced by rhBMP-2 was significantly inhibited as well as the expression of Osx (Osx mRNA expression: 0.378 ± 0.034 vs 0.134 ± 0.027, Osx protein expression: 0.353 ± 0.024 vs 0.155 ± 0.031, both P < 0.01). Meanwhile the mineralization nodules formed by HPDLCs induced by rhBMP-2 were fewer and delayed. BMP-2 has a significant positive regulatory role on the expression of Osx in HPDLCs. And p38 pathway is an important link of this regulatory process. Thus, as an important signaling pathway in osteogenic differentiation of HPDLCs, BMP-2/p38/Osx may be involved in periodontal tissue remodeling.
    Zhonghua yi xue za zhi 04/2013; 93(14):1104-8.
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    ABSTRACT: Objective: To investigate the relationship between growth patterns and mandibular posterior tooth-alveolar bone complex morphology in a Chinese population with normal occlusion. Methods: Forty-five patients with normal occlusion (23 males, 22 females) were included in this study. Among these patients, 20 displayed the vertical growth pattern, and 20 had the horizontal growth pattern, while the remaining patients displayed the average growth pattern. All of the patients underwent dental cone beam computed tomography (CBCT), which included the region of the mandibular posterior teeth and the alveolar. A linear regression analysis and a correlation analysis between the facial height index (FHI) and the alveolar bone morphology were performed. Results: The inclination of the molars, the thickness of the cortical bone, and the height of the mandibular bone differed significantly between patients with the horizontal growth pattern and those with the vertical growth pattern (P<0.05). Significant positive correlations were found between: the FHI and the inclination of the molars; the FHI and the thickness of the cortical bone; and the FHI and the height of the mandibular bone. Conclusions: The mandibular posterior tooth-alveolar bone complex morphology may be affected by growth patterns.
    Journal of Zhejiang University SCIENCE B 01/2013; 14(1):25-32. · 1.11 Impact Factor
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    ABSTRACT: To propose a method of establishing the reference mandibular plane (MP), which could be reestablished according to the coordinates of the reference points, and then facilitate the assessment of anterior alveolar morphology using cone beam computed tomography (CBCT), sixty patients with bimaxillary protrusion were randomly selected and CBCT scans were taken. The CBCT scans were transferred to Materialism's interactive medical image control system 10.01 (MIMICS 10.01), and three dimensional models of the entire jaws were constructed. Reference points determining the reference MP were positioned in the coronal, axial, sagittal windows, and the points were exactly located by recording their coordinates in the interfaces of software. The reference MP provided high intra-observer reliability (Pearson's r 0.992 to 0.999), and inter-observer reliability (intra-class correlation coefficients (ICCs) 0.996 to 0.999).
    Journal of Zhejiang University SCIENCE B 11/2012; 13(11):942-7. · 1.11 Impact Factor
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    ABSTRACT: To examine the expression of HIF-1α and VEGF after application of mechanical stretch on human dental pulp cells (HDPCs), and to investigate the role of them in maintaining homeostasis of dental pulp during orthodontic movement. HDPCs were subjected to 15% elongation by 1.0 Hz stretching frequency for 6, 12, 24, 48 and 72 h. The expression of HIF-1α and VEGF mRNA was measured by real-time polymerase chain reaction (PCR). SPSS12.0 software package was applied for statistical analysis. At the initial time point, HIF-1α mRNA had a weak expression. The mRNA level of HIF-1α increased gradually and then decreased towards its pre-pressure levels. The mRNA level of VEGF was upregulated in a time-dependent manner. The mRNA expression of HIF-1α and VEGF was enhanced by mechanical stress in HDPCs, which indicates that HIF-1α and VEGF may play an important role in retaining homeostasis of dental pulp during orthodontic movement. Supported by Excellent Young Researchers Foundation of Shandong Province(2008BS03050), Jinan Young Star of Science and Technology Program (20080111) and Independent Innovation Foundation of Shandong University (2011GN038, 2010TS095).
    Shanghai kou qiang yi xue = Shanghai journal of stomatology 10/2012; 21(5):501-5.
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    ABSTRACT: Abstract Objective: To evaluate, using multislice computed tomography (MSCT), the morphologic changes in the upper airway after large incisor retraction in adult bimaxillary protrusion patients. Materials and Methods: Thirty adult patients with bimaxillary protrusion had four first premolars extracted, and then miniscrews were placed to provide anchorage. A CT scan was performed before incisor retraction and again posttreatment. Three-dimensional (3D) reconstruction of the pre- (T1) and post- (T2) CT data was used to assess for morphological changes of the upper airway. A paired t-test was used to compare changes from T1 to T2. The relationship among the three variables (upper incisor retraction amount, upper airway size, and hyoid position) was analyzed by Pearson correlation coefficient. Results: The amounts of upper incisor retraction at the incisal edge and apex were 7.64 ± 1.68 mm and 3.91 ± 2.10 mm, respectively. The hyoid was retracted 2.96 ± 0.54 mm and 9.87 ± 2.92 mm, respectively, in the horizontal and vertical directions. No significant difference was observed in the mean cross-sectional area of the nasopharynx (P > .05) between T1 and T2, while significant differences between T1 and T2 were found in the mean cross-sectional areas of the palatopharynx, glossopharynx, and hypopharynx (P < .05); these mean cross-sectional areas were decreased by 21.02% ± 7.89%, 25.18% ± 13.51%, and 38.19% ± 5.51%, respectively. The largest change in the cross-sectional area is always noted in the hypopharynx. There was a significant correlation among the retraction distance of the upper incisor at its edge, the retraction distance of the hyoid in the horizontal direction, and the decrease of the hypopharynx. Conclusion: Large incisor retraction leads to narrowing of the upper airway in adult bimaxillary protrusion patients.
    The Angle Orthodontist 03/2012; · 1.18 Impact Factor
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    ABSTRACT: The purpose of this study was to evaluate three-dimensional (3D) dehiscence of upper anterior alveolar bone during incisor retraction and intrusion in adult patients with maximum anchorage. Twenty adult patients with bimaxillary dentoalveolar protrusion had the four first premolars extracted. Miniscrews were placed to provide maximum anchorage for upper incisor retraction and intrusion. A computed tomography (CT) scan was performed after placement of the miniscrews and treatment. The 3D reconstructions of pre- and post-CT data were used to assess the dehiscence of upper anterior alveolar bone. The amounts of upper incisor retraction at the edge and apex were (7.64±1.68) and (3.91±2.10) mm, respectively, and (1.34±0.74) mm of upper central incisor intrusion. Upper alveolar bone height losses at labial alveolar ridge crest (LAC) and palatal alveolar ridge crest (PAC) were 0.543 and 2.612 mm, respectively, and the percentages were (6.49±3.54)% and (27.42±9.77)%, respectively. The shape deformations of LAC-labial cortex bending point (LBP) and PAC-palatal cortex bending point (PBP) were (15.37±5.20)° and (6.43±3.27)°, respectively. Thus, for adult patients with bimaxillary protrusion, mechanobiological response of anterior alveolus should be taken into account during incisor retraction and intrusion. Pursuit of maximum anchorage might lead to upper anterior alveolar bone loss.
    Journal of Zhejiang University SCIENCE B 12/2011; 12(12):990-7. · 1.11 Impact Factor
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    ABSTRACT: Interleukin-17 (IL-17) is a cytokine secreted primarily by TH-17 cells that can stimulate the development of osteoclasts (osteoclastogenesis) in the presence of osteoblasts. IL-17, through osteoblasts, has indirect effects on the expression of bone resorption-related enzymes in osteoclasts, which have not been well clarified. Here, using MC3T3-E1 cells and RAW264.7 cells as osteoblasts and osteoclast precursors, we aimed to clarify these effects of IL-17A. MC3T3-E1 cells were cultured in the presence or absence of IL-17A for 72 h and the conditioned media collected (in the presence of soluble receptor activator of NF-кB ligand) and used to culture RAW264.7 cells. To assess osteoclast differentiation, adherent cells were fixed and stained for tartrate-resistant acid phosphatase (TRAP). Our analyses demonstrated that the number of TRAP-positive multinucleated cells increases after 3 days of culture in conditioned medium from IL-17A-treated cells compared to untreated controls. In addition, we observed that the levels of cathepsin K and MMP-9 increase in the conditioned medium from IL-17A-treated cells, whereas CA II expression levels remain unaffected. PGE2 production from MC3T3-E1 cells increased in the presence of IL-17A. Celecoxib, a specific inhibitor of cyclooxygenase-2 (COX-2), blocked both the IL-17A-stimulated increase in TRAP-positive multinucleated cells and the expression of cathepsin K and MMP-9. Furthermore, when MC3T3-E1 cells were transformed with small interfering RNA to silence COX-2 expression before IL-17A treatment, the resulting conditioned medium was less effective at inducing cathepsin K and MMP-9 expression in RAW264.7 cells. These results suggest that IL-17A induces the differentiation and function of osteoclasts via celecoxib-blocked prostaglandin, mainly PGE2, in osteoblasts.
    Biochimie 01/2011; 93(2):296-305. · 3.14 Impact Factor
  • Tao Lv, Ding Bai, Chun-Ling Wang
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    ABSTRACT: To evaluate the indication and characteristics of lower incisor extraction orthodontics. Thirty-four lower incisor extracted patients with satisfied effect were included in the study. The lateral cephalometric radiographs and casts were measured to observe the change before and after orthodontic treatment, then the difference was analyzed with paired-samples t test using SPSS11.0 software package. Different degree mismatch in Bolton index was found in most patients. The measurements of the upper anterior dental arch length and the U1-SN angle were significantly decreased (P<0.01). The upper anterior dental arch width and the U1-L1 angle were found significantly increased (P<0.01). Mandibular incisor extraction can be an effective treatment option in selected cases, particularly in those Class II malocclusion patients with 2-premolar-extraction. To reach an ideal effect with matched dental arch and ideal occlusion, one should pay attention to the indication and the incisor protrusion. Supported by Key Science and Technology Program of Shandong Province (Grant No.2010GSF10269).
    Shanghai kou qiang yi xue = Shanghai journal of stomatology 12/2010; 19(6):575-8.
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    ABSTRACT: The computer aided design and computer aided manufacture (CAD/CAM) template was fabricated basing on CT data of completely edentulous jaws, and the accuracy of template was evaluated by assessment of the deviation between the actual and planning position of the implant after the registration of pre- and post-operative CT images. The CAD/CAM templates for 4 completely edentulous jaws were designed and fabricated basing on the pre-operative CT data and the stone models of the jaws sample. And 14 implants were placed in the posterior region of the jaws aided by the CAD/CAM template. The pre- and post-operative CT was registered by the point to point method, and the deviation between actual and virtual implants was measured to assess the accuracy of the template. With the aid of CAD/CAM template, the deviations of the position at the tail of the implant, at the tip of the implant and the projected deviation of angle were (0.19 +/- 0.07) mm, (0.47 +/- 0.12) mm, and 1.790 +/- 0.68 degrees respectively, and the deviations of the position at the bucco-palatal, disto-mesial, vertical direction were (0.22 +/- 0.08) mm, (0.25 +/- 0.06) mm, (0.30 +/- 0.11) mm at the tip respectively. Within the limits of this study, the results verify the accuracy of CAD/CAM template and support its use for safety implant placement.
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 10/2010; 28(5):517-21.
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    ABSTRACT: Our objective was to enable accurate miniscrew placement after preoperative simulation. We developed a new template for miniscrew placement and evaluated its accuracy. Eleven patients who had bimaxillary protrusion were scanned with computed tomography. The 3-dimensional computed tomography data were used to produce, with stereolithography apparatus, a template for accurate miniscrew placement. The interradicular space available for miniscrew placement was calculated in the 3-dimensional images. Postoperative computed tomography images were matched with preoperative images to calculate the deviations between the planned and actual placements. The distance for placement of a miniscrew between 2 roots was 4.12 mm (SD, 0.25 mm; range, 3.7-4.5 mm). The placed miniscrews showed an average angular deviation of 1.2 degrees (SD, 0.43 degrees ; range, 0.6 degrees -2.41 degrees ) compared with the plan, whereas the mean linear distomesial deviation was 0.42 mm (SD, 0.13 mm; range, 0.15-0.6 mm) at the tip. The proposed template has high accuracy and will be especially useful for patients who require precise miniscrew placement.
    American journal of orthodontics and dentofacial orthopedics: official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 06/2010; 137(6):728.e1-728.e10; discussion 728-9. · 1.33 Impact Factor
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    ABSTRACT: INTRODUCTION: Our objective was to enable accurate miniscrew placement after preoperative simulation. We developed a new template for miniscrew placement and evaluated its accuracy. METHODS: Eleven patients who had bimaxillary protrusion were scanned with computed tomography. The 3-dimensional computed tomography data were used to produce, with stereolithography apparatus, a template for accurate miniscrew placement. The interradicular space available for miniscrew placement was calculated in the 3-dimensional images. Postoperative computed tomography images were matched with preoperative images to calculate the deviations between the planned and actual placements. RESULTS: The distance for placement of a miniscrew between 2 roots was 4.12 mm (SD, 0.25 mm; range, 3.7-4.5 mm). The placed miniscrews showed an average angular deviation of 1.2 degrees (SD, 0.43 degrees ; range, 0.6 degrees -2.41 degrees ) compared with the plan, whereas the mean linear distomesial deviation was 0.42 mm (SD, 0.13 mm; range, 0.15-0.6 mm) at the tip. CONCLUSIONS: The proposed template has high accuracy and will be especially useful for patients who require precise miniscrew placement.
    American journal of orthodontics and dentofacial orthopedics: official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 06/2010; 137(6):728-729. · 1.33 Impact Factor
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    ABSTRACT: To examine the expression of Osterix (Osx) mRNA and protein after application of mechanical force on human periodontal ligament cells (HPDLCs), and to investigate the role of Osx in orthodontic alveolar bone remodeling. HPDLCs were isolated and cultured in vitro with explant method. Approximately 2.5 x 10(5) cells were seeded onto six-well cell culture plates and then were exposed to centrifugal force for 1, 2, 4, 6, 8 or 12 h at 631 r x min(-1). The expression of Osx mRNA and protein was measured by reverse transcription-polymerase chain raction (RT-PCR) and Western blot respectively. Immunofluorescence assay was used to detect the expression and subcellular At the initial time point, Osx mRNA had a weak exlocalization of Osx protein by green fluorescence. pression and protein was not detected. Under the mechanical stimulation, both mRNA and protein levels of Osx were upregulated in a time-dependent manner. Furthermore, Osx protein was translocated gradually from the cytosol into the cell nuclei. The expression and activation of Osx were enhanced by mechanical stress in HPDLCs, which indicates that Osx may play an important role in HPDLCs osteogenic differentiation and periodontal tissue remodeling induced by mechanical stress.
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 04/2010; 28(2):214-8, 228.
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    ABSTRACT: To investigate the skeletodental factors relating to the chin point deviation of facial asymmetry in skeletal Class III malocclusion patients using three-dimensional computed tomography. Forty-one adult female patients with class III malocclusion, who underwent three-dimensional CT examination before orthodontics treatment, were assigned as group of symmetry or group of asymmetry according to the amount of chin point deviation from the facial midline. Midfacial and mandibular variables were measured. The data was analyzed with SPSS13.0 software package. Patients in the group of asymmetry showed higher positions of the upper canine and first molar, shorter ramus height, more superior positioning of gonion on the deviated side, more mesial and frontal inclination of the ramus, medial and frontal positioning of gonion on the opposite side than the group of symmetry. Menton deviation correlated significantly with the difference of ramus height between the 2 sides ramus, ramus height in the deviated side and other skeletodental factors. Facial asymmetry in Class III patients is due to the overgrowth,frontal and mesial inclination of the ramus in the opposite side.
    Shanghai kou qiang yi xue = Shanghai journal of stomatology 02/2010; 19(1):6-10.
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    ABSTRACT: During orthodontic tooth movement, cytokines released from periodontal ligament fibroblasts and alveolar bone osteoblasts can alter the process of bone remodeling. Recently, interleukin-17 (IL-17) was found to stimulate osteoclastic resorption through osteoblasts by inducing receptor activator of nuclear factor κB ligand (RANKL) expression. However, the relationship between mechanical stress and IL-17 production by osteoblasts is not clear. Therefore, we examined the effect of compressive force on the expressions of IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, IL-17F, and their receptors (IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE) using MC3T3-E1 cells as osteoblast-like cells. We also examined the effect of IL-17A on the expression of IL-17Rs, RANKL, macrophage colony-stimulating factor (M-CSF), and osteoprotegerin (OPG). The cells were cultured with or without continuous compressive force (1.0 and 2.0 g/cm(2)) for up to 24 hr. The cells were also cultured with or without IL-17A (0.1, 1.0, or 10 ng/ml) for up to 72 hr. The mRNA expressions of IL-17s and their receptors were estimated by real-time polymerase chain reaction. The expression levels of IL-17s and their receptors increased depending on the compressive force. The addition of IL-17A increased the expression of IL-17RA, IL-17RB, IL-17RC, IL-17RE, RANKL, and M-CSF, whereas it decreased OPG expression. These results indicate that compressive force induces the expression of IL-17s and their receptors in osteoblast-like cells and that IL-17s and their receptors produced in response to compressive force may affect osteoclastogenesis through the expression of RANKL, M-CSF, and OPG.
    Connective tissue research 01/2010; · 1.55 Impact Factor
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    ABSTRACT: To evaluate the influence of periodontal ligament (PDL) injury on initial stability for immediately loaded mini-implant anchorage. The sample consisted of 153 adult patients with maxillary protrusion deformity. Guiding by the positioning device designed by Choi, 306 mini-implants were inserted by self-tapping in the upper right and left buccal areas between the first molars and second premolars. The mini-implants were divided into two groups according to CT scanning. The mini-implant was absolutely separated from PDL (group I), the mini-implant appeared to touch or overlay on PDL, but not contact to the adjacent roots (group II). If orthodontic force could be applied to the mini-implants for four months, the mini-implant was recorded as successful anchorage. After immediate loading for four months, the analyses were completed by SPSS 9.0 software. Of the 306 inserted mini-implants, 162 were absolutely separated from PDL, 136 appeared to touch or overlay on PDL, but not contact to the adjacent roots, and 8 were excluded from this study because of injury to the adjacent root. The success rates of group I and II were 87.0% and 65.4% respectively. There were significant differences in the success rates between the two groups (P<0.001). The differences between the two groups in distribution of the upper right and left area had statistical significance (P<0.05). PDL injury is one of the main reasons leading to early loosening of the mini-implant.
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 05/2009; 27(2):224-6, 236.
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    ABSTRACT: To determine the influence of chin prominence on preferred lip position in profile. The average profile was constructed from the profile of a young Chinese man who has typical Chinese facial profile. Changes in chin position were established by altering the antero-posterior position by protruding or retruding the chin in increments of 5 degrees and 10 degrees from the average profile. The lips were then protruded or retruded in 1mm increments from the average profile and 9 silhouettes were arranged respectively. One hundred and eighty college students were asked to rate the top three most favored, well-balanced profiles.SPSS13.0 software package was used to compare the differences in the scores between the top three most favored profiles and the other profiles. Slightly retruded lip positions were preferred for the average profile.The scores in top three profiles were significantly larger than the other profiles(P<0.05);The raters tended to prefer more retruded lip positions as the facial convexity decreased and more protruded lip positions as the facial convexity increased. The chin position does significantly impact preferred lip position and different esthetic standards should be applied to the various profiles encountered in clinical practice.The results might be helpful in decisions between extraction and nonextraction treatment in borderline cases.
    Shanghai kou qiang yi xue = Shanghai journal of stomatology 12/2008; 17(6):598-602.
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    ABSTRACT: To investigate effects of non-surgical treatment on temporal mandibular joint(TMJ) of adult low-angle subjects with severe skeletal Class III deformity. Thirteen low-angle patients with severe skeletal Class III malocclusion (male 5, female 8) were included in the study. The average age was 21.3 years old. They were treated with OPA-K straight wire technique. Helkimo index evaluation was made before and after treatment. Lateral cephalometric films and corrected TMJ lateral cephalometric radiograghs were taken before and after treatment, and linear and area measurement were observed. All data were analyzed with SPSS 12.0 software. After non-surgical treatment, Helkimo indexes of all patients redistributed. The line distance and area of anterior space in TMJ increased while the posterior space decreased. Linear percent decreased from 20.81% to 8.04%, and area proportion decreased from 1.62 to 1.01. Anterior space was the same as the posterior. Condyles and mandibles were retruded. After non-surgical therapy in adult low-angle subjects with severe skeletal Class III malocclusion, condyles remove posteriorly from more anterior position to normal concentric position, and temporo-mandibular disorders symptom is relieved and cured effectively.
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 11/2007; 25(5):463-6, 469.
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    ABSTRACT: This study was designed to examine the changes of mRNA and protein levels of activating transcription factor-4 after centrifugal force stimulation in cultured human periodontal ligament (PDL)cells. Human PDL cells were cultured by sequential digestio, and then stimulated by centrifugal force (167g) for 10, 30, 60, 90, 120 and 240 minutes. The changes of mRNA and protein levels of ATF4 were analyzed by semi-quantitative RT-PCR and Western blotting. The data was analyzed with SPSS11.5 software package for ANOVA. Unstimulated human PDL cells exhibit an ATF4 mRNA expression, but very low level of protein; Immediately 10 minutes after force application, the mRNA and protein levels of ATF4 increased(P>0.05); at 30-minute,the mRNA level increased significantly to a peak level(P<0.01), at 60-minute, the protein level increased significantly to a peak level(P<0.01); at 90-minute, mRNA and protein levels decreased, but still higher than the control(P<0.01); after 120 minutes, mRNA and protein levels decreased to control levels(P>0.05). Centrifugal force stimulates ATF4 gene expression within a narrow time frame: a temporary increase of ATF4 expression and a fast downregulation back to its preloading level. This study demonstrates that ATF4 may play a critical role in orthodontic alveolar bone remodeling.
    Shanghai kou qiang yi xue = Shanghai journal of stomatology 08/2007; 16(4):422-6.
  • Kun Zhu, Chun-ling Wang, Juan Wang, Yan-hong Zhao
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    ABSTRACT: To measure the frictions between FAS bracket and stainless steel wire under different two conditions, and compare two traditional self-ligating brackets. FAS bracket was a new-style self-ligating bracket with a friction adjusting system (FAS) to adjust the friction as the wires slide in the bracket. Firstly, FAS bracket 20 times of original size was made, then the frictions were measured respectively made by the steel round wires of diameters 8.128 0 mm or the steel square wires in size of 9.1440 mm x 12.7000 mm. It was divided into two adjusting states, and used the same method to measure Damon III and SPEED bracket in 20 times of original size. With the shim entirely drew in, all the frictions of the arch wire had no significant difference with the Damon III. When 8.1280 mm stainless steel round wire was used, SPEED bracket had no significant difference with FAS. When 9.1440 mm x 12.7000 mm square wire was used, they had significant difference (P < 0.05). On turning half a circle, all the frictions of the arch wire had significant difference with two tradition bracket (P < 0.01). The new-style FAS bracket can adjust the friction efficiently. Under no pressure state, the friction force is similar to Damon III. Under pressure state, FAS bracket locks the wires, and provides the sliding of wires.
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 08/2007; 25(4):371-4.
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    ABSTRACT: To investigate the effects of orthodontic treatment on temporomandibular joint (TMJ) in adult low-angle patients with skeletal class III malocclusion. Sixteen adult female low-angle patients with skeletal class III malocclusion were included in the study. All patients were treated with OPA-K straight wire technique. Lateral cephalometric and corrected transcranial projection films were taken before and after treatment. Cephalometric analysis was carried out. All data were analyzed statistically. After orthodontic treatment, the linear measurement and area of anterior space in TMJ increased by 0.27 mm (P < 0.001) and 0.70 mm(2) (P < 0.01), respectively, while the posterior space decreased by 0.24 mm and 0.67 mm(2), respectively (P < 0.001). Linear ratio decreased from 22.13% to 9.64% (P < 0.001), and area proportion decreased from 1.56 to 1.19 (P < 0.01). Anterior space became equal to the posterior space. Cephalometric analysis showed that point Co, Ar, Go and Pg were all retruded (P < 0.05). After orthodontic therapy, the condyle moved posteriorly to normal concentric position, which would be helpful in alleviating temporomandibular disorders (TMD) symptom in adult low-angle patients with skeletal class III malocclusion.
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 08/2007; 42(8):471-4.

Publication Stats

46 Citations
11.86 Total Impact Points

Institutions

  • 2013
    • Tianjin Medical University
      T’ien-ching-shih, Tianjin Shi, China
  • 2010–2013
    • Shandong University
      • Department of Oral Orthodontics
      Jinan, Shandong Sheng, China
  • 2012
    • Shandong Qianfoshan Hospital
      Chi-nan-shih, Shandong Sheng, China
  • 2002–2010
    • University of Jinan (Jinan, China)
      Chi-nan-shih, Shandong Sheng, China