T L Zaets

Publications (60)4.14 Total impact

• Article: [Fibronectin as a part of the wound exudate and its importance in wound healing].

  V A Lavrov, T L Zaets
  Biulleten' eksperimental'noĭ biologii i meditsiny 04/1998; 125(3):355-7.
• Article: Fibronectin as a component of wound exudate and its significance for wound healing

  V. A. Lavrov, T. L. Zaets
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  ABSTRACT: Fibronectin concentration is much lower in wound exudate from the zone of operation for postoperational ventral hernia than in blood plasma. It gradually increases, reaching the plasma level before the end of exudation and wound healing.
  Bulletin of Experimental Biology and Medicine 01/1998; 125(3):316-317. · 0.27 Impact Factor
• Article: Enteral hyperalimentation of burned patients: the possibility of correcting metabolic disorders by the early administration of prolonged high calorie evenly distributed tube feeds.

  V K Sologub, T L Zaets, A V Tarasov, M R Mordkovitch, Yashin AYu
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  ABSTRACT: Metabolic processes and the ways they may be treated were investigated in severely burned patients receiving prolonged high calorie evenly distributed tube feedings. It was shown that in critically ill patients the absorption of nutrients in the upper regions of the intestine was slightly impaired but the ability to absorb was preserved, which made it possible to provide prolonged evenly distributed tube feeding. For these purposes we used the nutrient mixture 'Combustal'. Restoration of nitrogen balance could be reached within about 10 days after starting tube feeding. However, the creatine excretion remained high, a manifestation of increased dystrophy of muscle tissue. Pseudocholinesterase activity in serum was also decreased, suggesting subnormal biosynthetic processes. To provide the full correction to normal of the metabolic processes the tube feeding with 'Combustal' should be given for at least a month.
  Burns 07/1992; 18(3):245-9. · 1.96 Impact Factor
• Article: [Water-soluble phosphorus-containing forms of ionol in experimental treatment of thermal burns].

  T l Zaets, E E Nifant'ev, V A Lavrov, T S Kukhareva, I A Soldatova
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  ABSTRACT: The authors studied the membrane-stabilizing effect of two water-soluble preparations of antioxidants, analogues of ionol, in thermal burns. It was found that both preparations increase somewhat to a different degree the resistance of the red cell membranes to peroxide compounds and reduce hemolysis which is very characteristic of the first minutes and hours after the thermal trauma. The preparations alter the electrical properties of the red cells and affect the activity of phospholipases in blood plasma.
  Patologicheskaia fiziologiia i eksperimental'naia terapiia 02/1991;
• Article: [Changes in electric indices of blood in the early period after burns].

  V A Lavrov, T L Zaets
  Biulleten' eksperimental'noĭ biologii i meditsiny 06/1990; 109(5):440-2.
• Article: [Changes in several characteristics of the erythrocyte membrane and erythrocyte structure in severe burns in animal experiments].

  T L Zaets, V A Lavrov, A I Marchuk, I M Nosova
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  ABSTRACT: It is determined in experiments on rats that the IIIB degree thermal injuries of 20% of the total body surface significantly reduce the erythrocytic membrane's resistance and cause the production of peroxides in 15 minutes after trauma. Simultaneously the electrical properties begin to change. The structure of erythrocytes is also altered. In 30 minutes post injury these alterations are in progress, but in 60 minutes they are less expressed. The structure of the erythrocytes is significantly altered. The authors consider that the influence of membranotoxic factors--the products of free radicals' reactions and phospholipases--is accounted for all noticed alterations.
  Biulleten' eksperimental'noĭ biologii i meditsiny 02/1990; 109(1):27-30.
• Article: [The effect of tubal hyperalimentation on the metabolic processes in patients with severe burns].

  M I Kuzin, V K Sologub, T L Zaets, A V Tarasov, M R Mordkovich
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  ABSTRACT: High caloric probe hyperalimentation used in 37 burned patients in addition to routine ration resulted in normalization of metabolic processes due to the inhibition of biopolymer degradation and stabilization of biological membranes followed by the activation of anabolic processes.
  Vestnik khirurgii imeni I. I. Grekova 03/1988; 140(2):61-6.
• Article: [Therapeutic plasmapheresis in burns].

  M I Kuzin, V K Sologub, T L Zaets, A I Marchuk, V A Lavrov
  Klinicheskaia meditsina 03/1988; 66(2):116-20.
• Article: [Tube hyperalimentation in burns].

  M I Kuzin, V K Sologub, A V Tarasov, T L Zaets, M R Mordkovich
  Sovetskaia meditsina 02/1988;
• Article: [Blood phospholipases in burn shock].

  T L Zaets, V K Sologub, V I Nikulin, V A Lavrov, B Dakova
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  ABSTRACT: The activity of blood plasma phospholipases A and C has been observed during burn shock periods in patients with severe burns affecting more than 20% of the body surface. It was experimentally demonstrated that the enzyme plasma activity increased 30 minutes after burning. Simultaneously, intensification of lipid peroxidation took place. Phospholipases are suggested to liberate from the damaged tissues with their following activation by free-radical products.
  Biulleten' eksperimental'noĭ biologii i meditsiny 05/1987; 103(4):403-4.
• Article: [Minimal and optimal number of laboratory studies in deep and extensive burns].

  V K Sologub, T L Zaets
  Laboratornoe delo 02/1987;
• Article: [The hyperalimentation of burn patients].

  A V Tarasov, T L Zaets, M R Mordkovich
  Klinicheskaia khirurgiia 02/1987;
• Article: [Plasmapheresis combined with hemosorption in the treatment of burns].

  V K Sologub, A I Marchuk, T L Zaets, N A Oliunina, V A Lavrov
  Khirurgiia 12/1986;
• Article: [Therapeutic plasmapheresis in acute burn toxemia].

  V K Sologub, A I Marchuk, T L Zaets, V A Lavrov, E Sh Zinov'ev
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  ABSTRACT: Curative plasmapheresis was used in 10 critically burned patients at the stage of acute burn toxemia with the delirious syndrome with the unfavourable prognosis. Good immediate results were obtained in all the patients: psychic disorders were arrested by the end of the procedure. Clinico-laboratory data have shown the curative plasmapheresis to be an effective detoxicating method resulting in the elimination of various toxic substances from the organism.
  Vestnik khirurgii imeni I. I. Grekova 07/1986; 136(6):127-32.
• Article: [Effectiveness of tube feeding in burn injury patients].

  M I Kuzin, V K Sologub, A V Tarasov, M R Mordkovich, T L Zaets
  Klinicheskaia meditsina 03/1986; 64(2):44-54.
• Article: [Changes in the met- and leu-enkephalin levels in the rat brain during burn shock].

  T L Zaets, V K Sologub, M Ia Maĭzelis, A L Zabludovskiĭ, S N Shikhov
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  ABSTRACT: The dynamics of met-and leu-enkephalin content in the brain cortex and hypothalamus of rats with severe burn shock caused by 50% burns by boiling water were studied. A tendency towards burn-induced growth in leu-enkephalin hypothalamus level was observed, with the content of met-and leu-enkephalins in the hypothalamus significantly increasing 30 min later. Met-enkephalin content in the brain cortex also rises. 2 hours later the changes are less pronounced, with met-enkephalin hypothalamus level remaining elevated. The adaptive nature of changes, mobilization of endogenous anti-pain defensive mechanisms in severe burn shock and the role of hypothalamus structures in this process are suggested.
  Biulleten' eksperimental'noĭ biologii i meditsiny 02/1986; 101(1):10-1.
• Article: [Absorptive function of the intestines in severely ill patients].

  T L Zaets, V G Borisov, A V Tarasov
  Klinicheskaia meditsina 02/1984; 62(1):112-5.
• Article: [Structural and enzymatic disorganization of biological membranes in rat liver cells in thermal burns].

  T L Zaets
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  ABSTRACT: Permeability of hepatocyte cell membrane was studied from the release into blood of hepatospecific enzymes and from 5'-nucleotidase activity in plasma membranes. A study was also made of membrane permeability of mitochondria, lysosomes and microsomes in liver cells of burnt rats from the level of non-sedimented activity and activity of malate dehydrogenase, succinate dehydrogenase, cathepsin D and glucose-6-phosphatase in appropriate organelles. Permeability of cell and lysosomal membranes was demonstrated to be disordered within the first hours after burn. One day after burn generalized disturbance of membrane permeability in the cell was observed, followed by the release into cytosol of organelles template enzymes and a decrease in the activity of membrane-bound enzymes in these organelles. The alterations persisted during 7 days of observation.
  Biulleten' eksperimental'noĭ biologii i meditsiny 11/1983; 96(10):43-5.
• Article: [Effect of water-soluble antioxidants on the permeability of lysosomal membranes and on the structure of the liver in rats with thermal burns].

  T L Zaets, E B Burlakova, L I Muzykant, L S Evseenko
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  ABSTRACT: Experiments on rats were made to study the effect of water-soluble antioxidants on the permeability of lysosomal membranes of liver cells and liver structure under burn. Antioxidants were injected intraperitoneally shortly after burn, whereas examination was performed after one day. It has been discovered that one day after burn there takes place an appreciable destabilization of lysosomal membranes with the release of a lysosomal matrix enzyme, cathepsin D to the cytoplasm. Liver structure had undergone substantial changes by that time. After administration of water-soluble antioxidants lysosomal membranes got stabilized while liver structure manifested but insignificant disorders.
  Biulleten' eksperimental'noĭ biologii i meditsiny 11/1983; 96(10):29-32.
• Article: [Enzymatic hydrolysis of the burn crust].

  V K Sologub, I Chervenkov, E I Vyglenova, T L Zaets, M G Lagvilava
  Khirurgiia 04/1983;