[Show abstract][Hide abstract] ABSTRACT: The INT/WFC Photometric H-Alpha Survey of the Northern Galactic Plane (IPHAS)
is a 1800 square degrees imaging survey covering Galactic latitudes |b| < 5 deg
and longitudes l = 30 to 215 deg in the r, i and H\alpha\ filters using the
Wide Field Camera (WFC) on the 2.5-metre Isaac Newton Telescope (INT) in La
Palma. We present the first quality-controlled and globally-calibrated source
catalogue derived from the survey, providing single-epoch photometry for 219
million unique sources across 92% of the footprint. The observations were
carried out between 2003 and 2012 at a median seeing of 1.1 arcsec (sampled at
0.33 arcsec/pixel) and to a mean 5\sigma-depth of 21.2 (r), 20.0 (i) and 20.3
(H\alpha) in the Vega magnitude system. We explain the data reduction and
quality control procedures, describe and test the global re-calibration, and
detail the construction of the new catalogue. We show that the new calibration
is accurate to 0.03 mag (rms) and recommend a series of quality criteria to
select the most reliable data from the catalogue. Finally, we demonstrate the
ability of the catalogue's unique (r-H\alpha, r-i) diagram to (1) characterise
stellar populations and extinction regimes towards different Galactic
sightlines and (2) select H\alpha\ emission-line objects. IPHAS is the first
survey to offer comprehensive CCD photometry of point sources across the
Galactic Plane at visible wavelengths, providing the much-needed counterpart to
recent infrared surveys.
[Show abstract][Hide abstract] ABSTRACT: Surgery is the accepted treatment for infected acute pancreatitis, although mortality remains high. As an alternative, a staged management has been proposed to improve results. Initial percutaneous drainage could allow surgery to be posponed, and improve postoperative results. Few centres in Spain have published their results of surgery for acute pancreatitis.
[Show abstract][Hide abstract] ABSTRACT: We report the first case, to our knowledge, of Candida arteritis in a liver transplant recipient. The patient presented with hemorrhagic shock requiring emergency arterial repair. As Candida albicans, Candida tropicalis, and Candida glabrata were growing in the arterial tissue, the patient received antifungal therapy for 5 months, but died because of chronic graft dysfunction. No evidence of fungal infection was found in the tissue on postmortem examination.
[Show abstract][Hide abstract] ABSTRACT: The Javalambre-Physics of the Accelerated Universe Astrophysical Survey
(J-PAS) is a narrow band, very wide field Cosmological Survey to be carried out
from the Javalambre Observatory in Spain with a purpose-built, dedicated 2.5m
telescope and a 4.7 sq.deg. camera with 1.2Gpix. Starting in late 2015, J-PAS
will observe 8500sq.deg. of Northern Sky and measure $0.003(1+z)$ photo-z for
$9\times10^7$ LRG and ELG galaxies plus several million QSOs, sampling an
effective volume of $\sim 14$ Gpc$^3$ up to $z=1.3$ and becoming the first
radial BAO experiment to reach Stage IV. J-PAS will detect $7\times 10^5$
galaxy clusters and groups, setting constrains on Dark Energy which rival those
obtained from its BAO measurements. Thanks to the superb characteristics of the
site (seeing ~0.7 arcsec), J-PAS is expected to obtain a deep, sub-arcsec image
of the Northern sky, which combined with its unique photo-z precision will
produce one of the most powerful cosmological lensing surveys before the
arrival of Euclid. J-PAS unprecedented spectral time domain information will
enable a self-contained SN survey that, without the need for external
spectroscopic follow-up, will detect, classify and measure $\sigma_z\sim 0.5\%$
redshifts for $\sim 4000$ SNeIa and $\sim 900$ core-collapse SNe. The key to
the J-PAS potential is its innovative approach: a contiguous system of 54
filters with $145\AA$ width, placed $100\AA$ apart over a multi-degree FoV is a
powerful "redshift machine", with the survey speed of a 4000 multiplexing low
resolution spectrograph, but many times cheaper and much faster to build. The
J-PAS camera is equivalent to a 4.7 sq.deg. "IFU" and it will produce a
time-resolved, 3D image of the Northern Sky with a very wide range of
Astrophysical applications in Galaxy Evolution, the nearby Universe and the
study of resolved stellar populations.
[Show abstract][Hide abstract] ABSTRACT: The VST Photometric Halpha Survey of the Southern Galactic Plane and Bulge
(VPHAS+) is surveying the southern Milky Way in u, g, r, i and Halpha at 1
arcsec angular resolution. Its footprint spans the Galactic latitude range -5 <
b < +5 at all longitudes south of the celestial equator. Extensions around the
Galactic Centre to Galactic latitudes +/-10 bring in much of the Galactic
Bulge. This ESO public survey, begun on 28th December 2011, reaches down to
20th magnitude (10-sigma) and will provide single-epoch digital optical
photometry for around 300 million stars. The observing strategy and data
pipelining is described, and an appraisal of the segmented narrowband Halpha
filter in use is presented. Using model atmospheres and library spectra, we
compute main-sequence (u - g), (g - r), (r - i) and (r - Halpha) stellar
colours in the Vega system. We report on a preliminary validation of the
photometry using test data obtained from two pointings overlapping the Sloan
Digital Sky Survey. An example of the (u - g, g - r) and (r - Halpha, r - i)
diagrams for a full VPHAS+ survey field is given. Attention is drawn to the
opportunities for studies of compact nebulae and nebular morphologies that
arise from the image quality being achieved. The value of the u band as the
means to identify planetary-nebula central stars is demonstrated by the
discovery of the central star of NGC 2899 in survey data. Thanks to its
excellent imaging performance, the VST/OmegaCam combination used by this survey
is a perfect vehicle for automated searches for reddened early-type stars, and
will allow the discovery and analysis of compact binaries, white dwarfs and
[Show abstract][Hide abstract] ABSTRACT: To evaluate the outcome of patients with hepatocellular-cholangiocarcinoma (HCC-CC) or intrahepatic cholangiocarcinoma (I-CC) on pathological examination after liver transplantation for HCC.
Information on the outcome of cirrhotic patients undergoing a transplant for HCC and with a diagnosis of HCC-CC or I-CC by pathological study is limited.
Multicenter, retrospective, matched cohort 1:2 study. Study group: 42 patients undergoing a transplant for HCC and with a diagnosis of HCC-CC or I-CC by pathological study; and control group: 84 patients with a diagnosis of HCC. I-CC subgroup: 27 patients compared with 54 controls; HCC-CC subgroup: 15 patients compared with 30 controls. Patients were also divided according to the preoperative tumor size and number: uninodular tumors 2 cm or smaller and multinodular or uninodular tumors 2 cm or larger. Median follow-up: 51 (range, 3-142) months.
The 1-, 3-, and 5-year actuarial survival rate differed between the study and control groups (83%, 70%, and 60% vs 99%, 94%, and 89%, respectively; P < 0.001). Differences were found in 1-, 3-, and 5-year actuarial survival rates between the I-CC subgroup and their controls (78%, 66%, and 51% vs 100%, 98%, and 93%; P < 0.001), but no differences were observed between the HCC-CC subgroup and their controls (93%, 78%, and 78% vs 97%, 86%, and 86%; P = 0.9). Patients with uninodular tumors 2 cm or smaller in the study and control groups had similar 1-, 3-, and 5-year survival rate (92%, 83%, 62% vs 100%, 80%, 80%; P = 0.4). In contrast, patients in the study group with multinodular or uninodular tumors larger than 2 cm had worse 1-, 3-, and 5-year survival rates than their controls (80%, 66%, and 61% vs 99%, 96%, and 90%; P < 0.001).
Patients with HCC-CC have similar survival to patients undergoing a transplant for HCC. Preoperative diagnosis of HCC-CC should not prompt the exclusion of these patients from transplant option.
[Show abstract][Hide abstract] ABSTRACT: A retrospective cohort multicenter study was conducted to analyze the risk factors for tumor recurrence after liver transplantation (LT) in cirrhotic patients found to have an intrahepatic cholangiocarcinoma (iCCA) on pathology examination. We also aimed to ascertain whether there existed a subgroup of patients with single tumors ≤2 cm ("very early") in which results after LT can be acceptable. Twenty-nine patients comprised the study group, eight of whom had a "very early" iCCA (four of them incidentals). The risk of tumor recurrence was significantly associated with larger tumor size as well as larger tumor volume, microscopic vascular invasion and poor degree of differentiation. None of the patients in the "very early" iCCA subgroup presented tumor recurrence compared to 36.4% of those with single tumors >2 cm or multinodular tumors, p = 0.02. The 1-, 3- and 5-year actuarial survival of those in the "very early" iCCA subgroup was 100%, 73% and 73%, respectively. The present is the first multicenter attempt to ascertain the risk factors for tumor recurrence in cirrhotic patients found to have an iCCA on pathology examination. Cirrhotic patients with iCCA ≤2 cm achieved excellent 5-year survival, and validation of these findings by other groups may change the current exclusion of such patients from transplant programs.
American Journal of Transplantation 01/2014; · 6.19 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Introduction
Surgery is the accepted treatment for infected acute pancreatitis, although mortality remains high. As an alternative, a staged management has been proposed to improve results. Initial percutaneous drainage could allow surgery to be posponed, and improve postoperative results. Few centres in Spain have published their results of surgery for acute pancreatitis.
To review the results obtained after surgical treatment of acute pancreatitis during a period of 12 years, focusing on postoperative mortality.
Material and methods
We have reviewed the experience in the surgical treatment of severe acute pancreatitis (SAP) at Bellvitge University Hospital from 1999 to 2011. To analyse the results, 2 periods were considered, before and after 2005. A descriptive and analitical study of risk factors for postoperative mortality was performed
A total of 143 patients were operated on for SAP, and necrosectomy or debridement of pancreatic and/or peripancreatic necrosis was performed, or exploratory laparotomy in cases of massive intestinal ischemia. Postoperative mortality was 25%. Risk factors were advanced age (over 65 years), the presence of organ failure, sterility of the intraoperative simple, and early surgery (< 7 days). The only risk factor for mortality in the multivariant analysis was the time from the start of symptoms to surgery of < 7days; furthermore, 50% of these patients presented infection in one of the intraoperative cultures.
Pancreatic infection can appear at any moment in the evolution of the disease, even in early stages. Surgery for SAP has a high mortality rate, and its delay is a factor to be considered in order to improve results.
[Show abstract][Hide abstract] ABSTRACT: Background
We present the experience of the liver transplantation program at the Hospital of Bellvitge with 500 transplantations performed during 15 years, to describe changes in liver transplantation observed throughout the time and to analyze the long term results.
Patients and method
Five groups each one including 100 consecutive transplantations are studied.
The main indications were hepatocellular carcinoma (23%), alcoholic cirrhosis (22.8%), and post-hepatitis C cirrhosis (18.8%). Sixty-five retransplantations were performed in 59 patients (13%), being the more frequent indications arterial thrombosis (13 patients) and primary nonfunction of graft (10 patients). In 10 patients a hepatorenal transplantation was performed. In group I, the most frequent donor cause of death was cranial traumatism (80%), while in group V it was the vascular pathology (52%). There were other significative dif-ferences between these groups of patients (I vs V): patients with stage 2 or 3 from UNOS status (45 vs 19%), blood use (29.6  vs 4.6 [5.3] PRBC), ICU stay (13  vs 7.4  days), hospital stay (40  vs 23.7  days), rejection rate (46 vs 20%) and primary graft non-function (9 vs 3%). However, the infection rates (48 vs 54.5%) and biliary tract complications (26 vs 20%) have not shown statistically significant differences. Actuarial one and 5-year survival are 83 and 70% respectively.
An important and progressive improvement of liver transplantation results has been observed. However, de novo tumours, hepatitis C virus recurrence and chronic rejection can limit long term results.
[Show abstract][Hide abstract] ABSTRACT: Context. Be stars are probably the most rapid rotators among stars in
the main sequence (MS) and, as such, are excellent candidates to study
the incidence of the rotation on the characteristics of their non-radial
pulsations, as well as on their internal structure. Pulsations are also
thought to be possible mechanisms that help the mass ejection needed to
build up the circumstellar disks of Be stars. Aims: The purpose
of this paper is to identify a number of faint Be stars observed with
the CoRoT satellite and to determine their fundamental parameters, which
will enable us to study their pulsation properties as a function of the
location in the HR diagram and to search for correlations with the light
outbursts, which are possibly produced by discrete mass ejections. Methods: We identified those objects in the exofields of CoRoT
presenting the Be phenomenon using Hα surveys, as well as
automated methods based on pulsation properties that we finally
confirmed with FLAMES/GIRAFFE and X-shooter spectroscopic observations
at VLT/ESO, and with near-IR photometry. The spectra were 1) corrected
for the veiling effect, 2) treated with the GIRFIT code to determine
apparent fundamental parameters, and 3) corrected with the FASTROT code
for effects induced by the rapid rotation. Results: A list of 41
Be star candidates were found from photometric and spectroscopic
criteria. The spectral coverage useful for determining the fundamental
parameters was obtained for only about half of them. We then
spectroscopically identified 21 Be stars, two probable Be stars, and two
B stars contaminated by the Sh 2-284 nebulosity. A
short description of the spectral characteristics of each star is given.
The fundamental parameters and, in particular, the rotation frequency
νr (cycles per day) were all corrected for rotational
effects at rotation rates ranging from Ω/Ωc = 0.8
to 1.0. We have determined the positions of Be stars in the HR diagram
and find two of them located beyond the MS phase. Conclusions:
The well-determined fundamental parameters presented in this paper for a
statistically reliable sample of Be stars will enable us in forthcoming
papers to compare the properties of stars as pulsators either according
to their location in different regions of the HR diagram or with those
predicted from theory.
Appendices are only available in electronic form at http://www.aanda.org
Astronomy and Astrophysics 03/2013; 551:A130. · 5.08 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: OBJECTIVES: The aims of present study were to analyze the mortality risk factors in patients who had surgery for acute pancreatitis and to assess the importance of culturing peripancreatic tissue or fluid infection to ascertain the infection status. METHODS: Surgery was indicated both in patients with infected severe acute pancreatitis and in those with sterile pancreatitis with an unfavorable course. During surgery, cultures were taken of tissues (pancreatic necrosis and peripancreatic fat), intra-abdominal fluid, and bile. RESULTS: Of 107 patients operated on, fluid culture was analyzed in 94 patients, pancreatic necrosis in 61 patients, peripancreatic fat in 39 patients, and bile in 38 patients. Sterile pancreatitis with sterile ascites was found in 17 patients, sterile pancreatitis with infected ascites in 22, and pancreatic tissue infection in 60. Multivariate analysis demonstrated that sterile tissue cultures, age over 65 years, and fewer than 12 days between the beginning of pain and surgery were risk factors for mortality. Sterile pancreatitis with sterile ascites and sterile pancreatitis with infected ascites had similar postoperative mortality (41% and 50%, respectively); the group with pancreatic tissue infection had a lower mortality (20%). CONCLUSIONS: Early surgery, advanced age, and sterility of tissue cultures have been demonstrated as mortality factors for acute pancreatitis. Intra-abdominal fluid may be infected in the presence of sterile necrosis.
[Show abstract][Hide abstract] ABSTRACT: We investigate a region of the Galactic plane, between 120 <= l <= 140 and -1
<= b <= +4, and uncover a population of moderately reddened (E(B-V) \sim 1)
classical Be stars within and beyond the Perseus and Outer Arms. 370 candidate
emission line stars (13 <= r <= 16) selected from the INT Photometric H-alpha
Survey of the Northern Galactic plane (IPHAS) have been followed up
spectroscopically. A subset of these, 67 stars with properties consistent with
those of classical Be stars, have been observed at sufficient spectral
resolution (Delta_lambda \sim 2 - 4 Angstrom) at blue wavelengths to narrow
down their spectral types. We determine these to a precision estimated to be
+/- 1 sub-type and then we measure reddenings via SED fitting with reference to
appropriate model atmospheres. Corrections for contribution to colour excess
from circumstellar discs are made using an established scaling to H-alpha
emission equivalent width. Spectroscopic parallaxes are obtained after
luminosity class has been constrained via estimates of distances to
neighbouring A/F stars with similar reddenings. Overwhelmingly, the stars in
the sample are confirmed as luminous classical Be stars at heliocentric
distances ranging from 2 kpc up to \sim 12 kpc. However, the errors are
presently too large to enable the cumulative distribution function with respect
to distance to distinguish between models placing the stars exclusively in
spiral arms, or in a smooth exponentially-declining distribution.
Monthly Notices of the Royal Astronomical Society 01/2013; 430(3). · 5.52 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Context. Be stars are rapidly rotating stars with a circumstellar
decretion disk. They usually undergo pressure and/or gravity pulsation
modes excited by the κ-mechanism, i.e. an effect of the opacity of
iron-peak elements in the envelope of the star. In the Milky Way,
p-modes are observed in stars that are hotter than or equal to the B3
spectral type, while g-modes are observed at the B2 spectral type and
cooler. Aims: We observed a B0IVe star, HD 51452, with the
high-precision, high-cadence photometric CoRoT satellite and
high-resolution, ground-based HARPS and SOPHIE spectrographs to study
its pulsations in great detail. We also used the lower resolution
spectra available in the BeSS database. Methods: We analyzed the
CoRoT and spectroscopic data with several methods: Clean-NG, FreqFind,
and a sliding window method. We also analyzed spectral quantities, such
as the violet over red (V/R) emission variations, to obtain information
about the variation in the circumstellar environment. We calculated a
stellar structure model with the ESTER code to test the various
interpretation of the results. Results: We detect 189 frequencies
of variations in the CoRoT light curve in the range between 0 and 4.5 c
d-1. The main frequencies are also recovered in the
spectroscopic data. In particular we find that HD 51452 undergoes
gravito-inertial modes that are not in the domain of those excited by
the κ-mechanism. We propose that these are stochastic modes
excited in the convective zones and that at least some of them are a
multiplet of r-modes (i.e. subinertial modes mainly driven by the
Coriolis acceleration). Stochastically excited gravito-inertial modes
had never been observed in any star, and theory predicted that their
very low amplitudes would be undetectable even with CoRoT. We suggest
that the amplitudes are enhanced in HD 51452 because of the very rapid
stellar rotation. In addition, we find that the amplitude variations of
these modes are related to the occurrence of minor outbursts.
Conclusions: Thanks to CoRoT data, we have detected a new kind of
pulsations in HD 51452, which are stochastically excited
gravito-inertial modes, probably due to its very rapid rotation. These
modes are probably also present in other rapidly rotating hot Be stars.
The CoRoT space mission, launched on December 27, 2006, has been
developed and is operated by CNES, with the contribution of Austria,
Belgium, Brazil, ESA (RSSD, and Science Programs), Germany, and Spain.
This work uses observations partly made with the HARPS instrument at the
3.6-m ESO telescope (La Silla, Chile) in the framework of the
LP182.D-0356, as well as data obtained with Sophie at OHP and from the
BeSS database.Table 3 is available in electronic form at http://www.aanda.org
Astronomy and Astrophysics 10/2012; 546:A47. · 5.08 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Biliary strictures are the most common biliary tract complication after liver transplantation. There are scarce data on the results of hepaticojejunostomy (HJ) in the management of biliary complications after orthotopic liver transplantation (OLT). Thus, the role of surgery in this setting remains to be established. The aim of this study was to evaluate the results of surgical treatment of patients with biliary complications at our institution.
We reviewed 1000 consecutive liver transplantations performed at our institution from 1984 to 2007. We used a prospectively recorded database to identify patients who underwent HJ to treat any biliary tract complication.
Overall, 62 patients (6.2%) underwent HJ, 40 for an anastomotic and 7 for a non-anastomotic stricture as well as 15 for biliary leaks. Postoperative morbidity was 16%, and postoperative mortality 1.6%. There were 7 cases of anastomotic stenosis (11.3%). Four patients (5%) required retransplantation.
HJ is a safe procedure to manage biliary complications after OLT. It may be the first treatment choice especially for cases with anastomotic strictures.
[Show abstract][Hide abstract] ABSTRACT: El objetivo de este estudio fue analizar los factores pronósticos y las indicaciones quirÚrgicas de las metástasis hepáticas
de carcinoma colorrectal (CCR). Se realizaron 212 hepatectomías en 196 pacientes. No hubo un criterio fijo para la resección
con respecto al nÚmero o tamaño de las metástasis o la enfermedad extrahepática excepto que la exéresis tenía que ser macroscópicamente
El índice de resecabilidad fue del 91% (196/215). La mortalidad postoperatoria fue del 4,7%. Se efectuó la exéresis de metástasis
pulmonares en 14 pacientes. La supervivencia actuarial a 1, 3 y 5 años fue del 88%, 60% y 39%, respectivamente. La supervivencia
libre de enfermedad fue del 20% a los 5 años, pero el 48% de los pacientes estaban libres de recidiva hepática a los 5 años.
En el estudio multivariante, 4 metástasis y la invasión de márgenes fueron factores independientes de peor supervivencia.
La exéresis quirÚrgica es un tratamiento seguro y debe considerarse la terapéutica estándar en las metástasis hepáticas de
The purpose of this study was to investigate the prognostic factors and indications of surgical treatment of liver metastases
from colorrectal cancer (CRC).
One hundred ninety six patients were submitted to 212 liver resections. We had no predefined criteria of resectability with
regard to either the number or size of the tumors or the locorregional invasion, except that resection had to be complete
and macroscopically curative.
Resectability rate was 91% (196/215). Postoperative mortality was 4.7%. A pulmonary resection could be performed in 14 patients
with lung metastases. The actuarial survival rates at 1, 3 and 5 years were 88%, 60% and 39%, respectively. Five-year disease
free survival was 20%, but the rate of survival free of hepatic recurrence was 48% at 5 years. In the multivariate analysis,
four or more metastases and positive margin were independent predictors of poor outcome.
Surgical resection is safe and should be considered the standard treatment in patient with liver metastases of CRC.
Clinical and Translational Oncology 04/2012; 2(6):309-315. · 1.28 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: The Working Group on Active B Stars (WGABS) was re-established under IAU
Commission No. 29 at the IAU General Assembly in Montreal, Quebec,
Canada in 1979. Its main goal is to promote and stimulate research and
international collaboration in the field of active B stars. Originally
known as the Working Group on Be Stars, its name was changed at the
22nd IAU General Assembly in The Hague, Netherlands in 1994
when the research interests of the group were broadened to include
activity in all B stars, especially pulsating OB stars, interacting
binaries, stellar winds, and magnetic fields.
Proceedings of the International Astronomical Union 04/2012; 7(T28A):199-202.