J Rubí-Callejón

Hospital Torrecárdenas, Almeria, Unci, Andalusia, Spain

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Publications (7)9.05 Total impact

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    ABSTRACT: To use transcranial Doppler (TCD) sonography to determine if patients with migraine without aura have interictal hemodynamic abnormalities compared with patients who have episodic tension-type headache (TH). Thirty-six migraine patients without aura and 51 TH patients (age range, 16-50 years) who were diagnosed according to the criteria of the International Headache Society 1988 participated in the study. Forty-four healthy volunteers, matched for age and sex, formed the control group. Time-averaged mean velocity (TAMV), pulsatility index (PI), and breath-holding index (BHI) were measured via TCD sonography in the middle cerebral artery. TAMV was higher in migraine without aura than in episodic TH (p = 0.034). There were no differences between groups regarding PI or BHI. Our findings support the arteriolar vasodilatation theory in migraine without aura.
    Journal of Clinical Ultrasound 10/2007; 35(7):372-5. · 0.80 Impact Factor
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    ABSTRACT: To determine whether menstrual tension-type headache is a real disorder. An appendix was included in the second edition of the International Classification of Headache Disorders by the International Headache Society. Diagnostic criteria are proposed in this appendix for 2 types of menstrual migraine: pure menstrual migraine without aura and menstrually related migraine without aura. References to menstrual tension-type headache do not appear in this classification. In a neurological outpatient clinic 165 patients were identified in whom headache was related to menstruation and the criteria of the International Classification of Headache Disorders for menstrual migraine adapted to menstrual tension-type headache were applied. Twenty-one patients met the criteria of menstrual tension-type headache, 6 for pure menstrual tension-type headache, and 15 for menstrually related tension-type headache. Menstrual tension-type headache is a real condition that should be recognized in the International Classification of Headache Disorders.
    Headache The Journal of Head and Face Pain 02/2007; 47(1):100-3. · 3.19 Impact Factor
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    ABSTRACT: Vasomotor reactivity (VR) is the capability of the cerebral arterioles to dilate and to constrict in response to determined stimuli. Using transcranial doppler (TCD), there are various test to evaluate it, including the breath holding test. With this test, VR can be calculated two ways: using the increment percentage of the mean velocity with respect to the basal velocity (PIV) or by quantifying the apnea time to obtain what is call the breath holding index (PIV/apnea seconds). The objective of our study is to study the linear correlation between the PIV and the breath holding index. This was an observational study performed in a neurology ambulatory setting. A total of 128 subjects, age 16 to 50 years old, were included. We assessed VR using the breath holding test described by Markus and Harrison on the middle cerebral artery. The linear correlation between the two quantitative variables was analysed using Pearson's correlation coefficient. Pearson's correlation coefficient between the PIV and the breath holding index was 0.75 for a significance level of p < 0.0001. Given the good linear correlation between these two methods for calculating the VR using the breath holding test, we consider it is not necessary to calculate breath holding test time when using this test.
    Neurologia (Barcelona, Spain) 12/2005; 20(10):674-7. · 1.35 Impact Factor
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    ABSTRACT: Hymenoptera stings can give rise to a variety of conditions. The most common is a self-limiting local allergic reaction, but occasionally they may produce potentially serious systemic reactions. Neurological complications are rare, but very varied and of differing degrees of severity. Some such consequences are those of a demyelinating nature, which can affect the central and/or peripheral nervous system. Their exact pathogenesis remains unknown but an autoimmune mechanism has been suggested. We report the case of a 28-year-old female who had a clinical picture compatible with acute disseminated encephalomyelitis ten days after being stung several times by a bumblebee. The diagnosis was based on findings from magnetic resonance imaging and on the clinical-radiological course after a one-year follow-up. The patient was treated with massive doses of intravenous corticosteroids and immunoglobulins, which brought about partial recovery from the neurological deficit. Hymenoptera stings can produce demyelinating neurological complications, presumably related to the autoimmune system, which could benefit from treatment with immunomodulators such as corticosteroids, immunoglobulins or plasmapheresis.
    Revista de neurologia 42(7):408-10. · 0.93 Impact Factor
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    ABSTRACT: In recent years our knowledge of the pathophysiology and aetiology of reflex seizures and epilepsies has advanced significantly due to the contributions made by modern functional neuroimaging and neurophysiology techniques, as well as the findings of research being conducted in molecular biology. The aim of our review is to summarise and integrate these contributions in order to describe the current state of our knowledge on the subject. The fundamental pathophysiological pattern is common to all types of reflex epilepsy and is based on the existence of a hyperexcitable cortical or subcortical neuronal area that can respond to a physiological stimulus in an exaggerated manner. This focal hyperexcitability may derive from a predisposing genetic substrate (idiopathic reflex epilepsy) or from a focal cortical lesion (lesional reflex epilepsy). Some genetic substrates have been reported in isolated families and there are many candidate genes, but we still do not know enough about the genetic base. The lesion-based aetiology is very heterogeneous, but disorders affecting cortical development are the lesions with the greatest capacity to cause reflex epilepsy. Clinical expression is conditioned by the topography of the lesion and not by the type of underlying lesion. Future characterisation of reflex epileptic seizures and syndromes must include a diagnosis centred around three axes, that is, topographic, lesional and genetic.
    Revista de neurologia 43(12):745-52. · 0.93 Impact Factor
  • Revista de neurologia 41(6):383. · 0.93 Impact Factor
  • J Rubí-Callejón, A Arjona, P J Serrano-Castro
    Revista de neurologia 39(6):600; author reply 600. · 0.93 Impact Factor