K S Madhusudhan

All India Institute of Medical Sciences, New Delhi, NCT, India

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Publications (23)20.93 Total impact

  • Source
    Article: von Meyenburg’s complex in a patient with primary malignancy: role of MRI
    K. S. Madhusudhan, C. J. Das
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    ABSTRACT: von Meyenburg’s complexes are benign liver malformations histologically constituting cystic dilatations of the bile ducts, surrounded by abundant fibrous stroma. Appearance of these lesions on MRI is characteristic and a fine needle aspiration or biopsy can be avoided and judicious management planned. We report a case of esophageal carcinoma who had suspicious lesions in the liver on CT scan, which after MRI were confirmed as biliary hamartomas.
    Indian Journal of Surgery 04/2012; 71(2):98-100. · 0.08 Impact Factor
  • Article: Spontaneous rupture of benign mediastinal teratoma: A report of two cases.
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    ABSTRACT: Benign mediastinal teratomas are commonly asymptomatic and seldom cause complications. Spontaneous rupture into the pleura is rare and cross-sectional imaging is crucial in its early detection and planning a proper surgical approach. We report two cases of spontaneous pulmonary and pleural rupture of benign mediastinal teratoma and discuss the imaging appearances.
    Indian journal of medical and paediatric oncology 04/2012; 33(2):123-5.
  • Article: Renal iron deposition in aplastic anemia: Magnetic resonance imaging appearance.
    K S Madhusudhan, R Oberoi
    Indian Journal of Nephrology 04/2011; 21(2):134-5.
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    Article: Multifocal epithelioid hemangioendothelioma presenting with hemoptysis.
    K S Madhusudhan, D N Srivastava, S Gamanagatti
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    ABSTRACT: We present a case of multifocal epithelioid hemangioendothelioma occurring in an adolescent boy who presented with massive hemoptysis and showed a pulmonary perihilar mass with multiple lesions in the liver and two lytic lesions in the ribs on imaging. The diagnosis was confirmed by lung and liver biopsy. He was treated with oral steroids.
    The Indian Journal of Pediatrics 06/2010; 77(6):699-700. · 0.52 Impact Factor
  • Article: Sciatic hernia causing sciatica: MRI and MR neurography showing entrapment of sciatic nerve.
    Chitranjan, H Kandpal, K S Madhusudhan
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    ABSTRACT: Sciatic hernia is a rare condition with diverse clinical manifestations. We report a case of sciatic hernia causing sciatica, in which the diagnosis made on CT was subsequently confirmed on MRI including magnetic resonance neurography. The salient clinical and imaging features and a brief review are presented.
    The British journal of radiology 03/2010; 83(987):e65-6. · 2.11 Impact Factor
  • Article: A rare case of combined soft-tissue and intraosseous arteriovenous malformation of the hand with diffuse periosteal elevation: imaging appearances.
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    ABSTRACT: Arteriovenous malformations are uncommon congenital lesions of the hand. Although present at birth, they usually manifest later in life. Ultrasonography, MRI and digital subtraction angiography play an important role in the diagnosis of these lesions. We report the imaging appearances of an unusual case of combined soft-tissue and intraosseous arteriovenous malformation (AVM) of the hand with marked periosteal elevation in a 12-year-old child. Although associated skeletal changes are common, diffuse periosteal elevation owing to direct communication of the AVM with the subperiosteal space has not, to the best of our knowledge, been reported previously.
    The British journal of radiology 11/2009; 82(983):e219-24. · 2.11 Impact Factor
  • Article: Case report. Schwannoma of both intrahepatic and extrahepatic bile ducts: a rare case.
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    ABSTRACT: Schwannoma of the biliary tree is extremely uncommon, with only a few cases having been reported so far. They commonly present with obstructive jaundice. Although involvement of the extrahepatic duct is common, occurrence in the intrahepatic ducts has not been reported. We report a case of combined intrahepatic and extrahepatic schwannoma in a 46-year-old man presenting with obstructive jaundice.
    The British journal of radiology 10/2009; 82(982):e212-5. · 2.11 Impact Factor
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    Article: Endovascular embolization of pulmonary sequestration in an adult.
    Journal of vascular and interventional radiology: JVIR 10/2009; 20(12):1640-2. · 1.81 Impact Factor
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    Article: Tuberculosis of the thyroid gland: magnetic resonance imaging appearances.
    K S Madhusudhan, A Seith, R Khadgawat, P Das, S Mathur
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    ABSTRACT: Tuberculosis involving the thyroid gland is a rare occurrence. We report a case of cytologically-diagnosed thyroid gland tuberculosis in a 21-year-old man who presented with thyroid swelling of short duration, and describe the magnetic resonance (MR) imaging appearances of the lesion, which to our knowledge, has not been previously described. We also report a rare complication of abscess formation in the track of the fine needle aspiration. The intermediate signal intensity of the lesions on both T1- and T2-weighted MR images may provide a clue about tuberculosis, as clinical suspicion is low due to the rarity of the disease.
    Singapore medical journal 08/2009; 50(7):e235-8. · 0.73 Impact Factor
  • Article: Respiratory-triggered versus breath-hold diffusion-weighted MRI of liver lesions: comparison of image quality and apparent diffusion coefficient values.
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    ABSTRACT: The purpose of our study was to compare respiratory-triggered and breath-hold diffusion-weighted liver MRI and to assess the agreement in the apparent diffusion co-efficient (ADC) values between the two sequences. Forty-eight patients (27 men, 21 women; mean age, 45.2 years) with focal liver lesions underwent respiratory-triggered and breath-hold diffusion-weighted MRI (DWI) in addition to routine MRI. Both sequences had identical imaging parameters except for signal averages, which were 6 in respiratory-triggered and 2 in breath-hold sequences. A total of 92 lesions (maximum of three lesions per patient; 37 benign, 55 malignant) were evaluated. Lesions were confirmed by typical imaging appearance, histopathology, or follow-up. Signal-to-noise ratio (SNR) of the liver, contrast-to-noise ratio (CNR), and relative contrast ratio of the lesions were measured in each DWI sequence and were statistically compared using the Mann-Whitney U test. The ADC values of normal liver and each category of liver lesions in the two sequences were compared for agreement using Pearson's coefficient and reliability analysis scale. The SNR of the normal liver was significantly better on respiratory-triggered DWI than on breath-hold DWI. The mean CNR of metastases, hepatocellular carcinomas, and abscesses was significantly better in the respiratory-triggered DWI than in the breath-hold DWI sequences. The ADC values of liver and focal lesions measured by the two techniques showed good agreement. The SDs of the ADC values of normal liver were similar in the two sequences. Respiratory-triggered DWI should be preferred over breath-hold DWI for the evaluation of focal liver lesions because it provides better image quality and SNR without any compromise in the calculated ADC values.
    American Journal of Roentgenology 05/2009; 192(4):915-22. · 2.78 Impact Factor
  • Article: Comparison of intra-arterial digital subtraction angiography using carbon dioxide by 'home made' delivery system and conventional iodinated contrast media in the evaluation of peripheral arterial occlusive disease of the lower limbs.
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    ABSTRACT: To prospectively compare the feasibility, safety and diagnostic role of carbon dioxide (CO(2)) digital subtraction angiography (DSA) using a 'home made' delivery system with iodinated contrast medium (ICM) DSA in the evaluation of peripheral arterial occlusive diseases (PAOD) of lower limbs. Twenty-one patients (27 limbs; all men; mean age, 47.6 years) who presented with PAOD of lower limbs underwent DSA using both intra-arterial CO(2) and ICM. Conventional ICM DSA was performed first and used as gold standard. Carbon dioxide was then injected by hand using a locally improvised home made plastic bag delivery system. Patient tolerance was assessed subjectively. Arteries from aortic bifurcation to the ankle were independently evaluated by two radiologists and graded for stenosis using a five-point scale. For each patient, the quality of CO(2) DSA images were compared with the corresponding images of ICM DSA and an overall grade of 'good', 'acceptable' or 'poor' was assigned. Cohen's kappa coefficient was used to determine inter-observer agreement. Carbon dioxide opacified 86.2% (188/195) of major arteries and depicted stenosis adequately in 84.5% (191/226) of arterial segments. A good or acceptable image quality of CO(2) DSA was obtained in over 95% of patients. Infrapopliteal arteries were inadequately visualized. Mild pain was seen in six (28.6%) patients with both contrast agents; one patient developed severe pain during CO(2) DSA. Inter-observer agreement was good (k > 0.75) at 70% of the segments. Administration of CO(2) into lower limb arteries is well tolerated. Carbon dioxide DSA using the locally improvised home made delivery system is a feasible and safe alternative to ICM DSA in the evaluation of PAOD. It provides adequate imaging of arteries of lower extremities except infrapopliteal segments.
    Journal of Medical Imaging and Radiation Oncology 03/2009; 53(1):40-9. · 0.87 Impact Factor
  • Article: Creutzfeldt-Jakob disease: Importance of early magnetic resonance imaging.
    K S Madhusudhan, Chandan Jyoti Das
    Annals of Indian Academy of Neurology 01/2009; 12(1):52-3. · 0.93 Impact Factor
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    Article: Primary breast tuberculosis masquerading as carcinoma.
    K S Madhusudhan, S Gamanagatti
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    ABSTRACT: Although tuberculosis is a very common disease in endemic areas, isolated involvement of the breast is very rare. Any form of tuberculous mastitis may present with features of malignancy. Diagnosis is mainly based on identification of tubercle bacilli. We report a 50-year-old woman with primary tuberculous abscess of the breast which simulated carcinoma on mammography, and describe the importance of ultrasonography in differentiating abscess from malignancy.
    Singapore medical journal 02/2008; 49(1):e3-5. · 0.73 Impact Factor
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    Article: Pulmonary infections mimicking cancer: report of four cases.
    K S Madhusudhan, S Gamanagatti, A Seith, S Hari
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    ABSTRACT: Lung infections infrequently simulate cancer, and their differentiation, based on imaging findings, can sometimes be difficult. The infections may be fungal, mycobacterial, parasitic or, rarely, viral. A biopsy is required to prove the infectious nature of the lesions. A specific diagnosis is necessary for initiation of appropriate therapy. We report four cases of chronic pulmonary infections, which were wrongly diagnosed as bronchogenic carcinoma based on radiological features. We also reviewed the existing literature.
    Singapore medical journal 01/2008; 48(12):e327-31. · 0.73 Impact Factor
  • Article: Esophageal lichen planus: a case report and review of literature.
    K S Madhusudhan, Raju Sharma
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    ABSTRACT: Lichen planus is a rare cause of esophagitis and esophageal stricture. It is invariably associated with oral mucosal involvement and the diagnosis has to be considered in these patients who present with dysphagia. We present a case of esophageal stricture secondary to lichen planus.
    Indian Journal of Dermatology 01/2008; 53(1):26-7.
  • Article: Esophageal duplication cyst causing unilateral hyperinflation of the lung in a neonate.
    K S Madhusudhan, A Seith, M Srinivas, A Kumar Gupta
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    ABSTRACT: Esophageal duplication cysts are rare congenital anomalies. Frequently asymptomatic, they may cause respiratory distress and feeding difficulties in infants. Unilateral hyperinflation of the lung due to compression of the bronchus by the cyst is rare. We report a case of a 4-day-old male neonate presenting with respiratory distress who had an esophageal duplication cyst causing obstructive hyperinflation of the right lung. The nature of the cyst was confirmed after surgery.
    Acta Radiologica 07/2007; 48(5):588-90. · 1.37 Impact Factor
  • Article: Hepatic hydatid cysts with biliary, and peritoneal rupture and transdiaphragmatic migration.
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    ABSTRACT: Hydatid disease is a parasitic infection that most commonly involves the liver. Imaging plays a vital role in the diagnosis of this disease. Rupture of the cyst can give rise to a wide spectrum of complications. We describe a case of hepatic hydatid cyst with rupture into the biliary tree, right pleural cavity and dissemination into the peritoneal cavity, with associated splenic hydatid cysts. MRI may be a useful non-invasive diagnostic tool in such disseminated cases to define the complete extent of the disease.
    Tropical gastroenterology: official journal of the Digestive Diseases Foundation 27(2):93-6.
  • Article: Update in liver imaging.
    C J Das, S B Paul, K S Madhusudhan, M S Gulati
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    ABSTRACT: Over the last decade, liver imaging has experienced a revolution providing a bewildering array of options for detection and characterisation of liver lesions. Cross-sectional imaging modalities like computed tomography and magnetic resonance imaging have improved in speed and resolution, thereby facilitating multiphasic scanning of the liver. The advent of the use of contrast agents for ultrasonography and magnetic resonance imaging has further paved the way for definitive diagnosis in an attempt to obviate the need for invasive diagnosis. This article captures advances made in ultrasonography, computed tomography, magnetic resonance imaging and positron emission tomography and brings the specialist up to date with the latest in liver imaging.
    Tropical gastroenterology: official journal of the Digestive Diseases Foundation 28(4):149-55.
  • Article: Giant hemangioma of liver presenting as deep vein thrombosis of the lower limbs.
    K S Madhusudhan, D N Srivastava, S Gamanagatti
    Journal of Postgraduate Medicine 55(4):290-1. · 1.26 Impact Factor
  • Article: Spontaneous closure of a traumatic intrarenal pseudoaneurysm.
    K S Madhusudhan, S Sharma, A Seth
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    ABSTRACT: Renal artery pseudoaneurysms caused by blunt abdominal trauma are uncommon. It requires treatment with angioembolization because of high risk of rupture. Spontaneous closure of the pseudoaneurysm is extremely unusual. We report a case of a 29-year-old male who developed a traumatic intrarenal pseudoaneurysm that later resolved spontaneously. This report provides an insight into the natural history of renal pseudoaneurysm and suggests a potential option of managing them conservatively.
    Journal of Postgraduate Medicine 55(2):124-6. · 1.26 Impact Factor