Publications (19)22.07 Total impact
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Article: Coronary arterial bypass surgery with beating heart in a patient with heparin-induced thrombocytopenia: Usage of thrombin inhibitor (Lepirudin; r-hirudin)
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ABSTRACT: One of the most important adverse drug reactions that physicians encounter is the life-threatening prothrombotic syndrome known as heparin-induced thrombocytopenia (HIT). In patients with a history of heparin-induced thrombocytopenia and coronary arterial disease, alternative anticoagulatory regimens are needed during cardiac surgery for prevention of thrombosis. Treatment options for such patients now generally include the use of alternative anticoagulants such as lepirudin, bivalirudin, argatroban or danaparoid. In this article, we present a case where heparin-induced thrombocytopenia was properly performed coronary arterial bypass grafting by using lepirudin. (This sentence is confusing) KeywordsLepirudin-Heparin-induced thrombocytopenia-Coronary arterial bypss surgery-Heparin-AnticoagulationCentral European Journal of Medicine 04/2012; 5(2):150-153. · 0.31 Impact Factor -
Article: Sinus of Valsalva thrombosis causing peripheral embolism.
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ABSTRACT: A 44-year-old woman was admitted with the diagnosis of peripheral arterial emboli. Peripheral angiography demonstrated total occlusion of the popliteal artery. The obstruction was successfully resolved with a Fogarty arterial embolectomy catheter. Both transthoracic and transesophageal echocardiography showed a mobile, round thrombus in the noncoronary sinus of Valsalva. The patient did not accept surgery, and anticoagulation with warfarin was initiated. One month after treatment, transthoracic echocardiography demonstrated disappearance of the thrombus in the noncoronary sinus of Valsalva. The patient did not experience any recurrent episode of systemic embolization. This is a rare case of peripheral embolism caused by a thrombus in the noncoronary sinus of Valsalva without aneurysm.Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 01/2011; 39(1):52-4. -
Article: Vascular ring: tracheoesophageal compression associated with symmetrical double aortic arch.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 02/2008; 35(2):209-10. · 0.65 Impact Factor -
Article: Prevention of reperfusion injury of the spinal cord in aortic surgery: an experimental study.
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ABSTRACT: We designed an experimental study to show the effects of some agents in order to prevent reperfusion injury of the spinal cord. Twenty rabbits were used and were divided into two groups in our study. Infrarenal abdominal aortic occlusion, between renal arteries and iliac bifurcations, was applied to the subjects in group 1 for only 30 min; in the group 2 subjects, on the other hand, intra-aortic diltiazem, N-acetylcysteine, and catalase combinations were applied after infrarenal abdominal aortic occlusion. The spinal cord functions of the subjects were assessed at the 48th hour after the operation according to Tarlov scoring, then cord tissue samples were taken for biochemical and histopathological studies. The group 2 subjects had better neurological functions than group 1 subjects (P < 0.01). In group 2; superoxide dismutase and glutathione peroxidase levels increased, while malondialdehyde and xanthine oxidase levels decreased as compared with group 1 (P < 0.05). A histopathological examination showed the group 2 samples to have fewer bleeding points and less neuron loss. We concluded that antioxidant agent combinations (diltiazem, N-acetylcysteine, and catalase) applied after ischemia might thus help protect the spinal cord against ischemia and reperfusion injury.Surgery Today 01/2008; 38(3):237-44. · 1.22 Impact Factor -
Article: Primary benign schwannoma of the left ventricle coursing under the left anterior descending artery.
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ABSTRACT: A 57-year-old female patient with a mass adjacent to the left ventricle coursing along the left anterior descending artery has been reported. The maximum possible resection was performed at a maximum degree; however without complete removal. Histological examination revealed a benign primary schwannoma of the heart. To our knowledge, this is the first reported case of benign schwannoma of left ventricle in an adult.Echocardiography 12/2007; 24(10):1093-5. · 1.24 Impact Factor -
Article: The impact of intraoperative transit time flow measurement on the results of on-pump coronary surgery.
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ABSTRACT: The purpose of this study is to evaluate the effect of detection of graft dysfunction by intraoperative transit time flow measurement (TTFM) on the surgical results of on-pump coronary artery bypass grafting. Two hundred patients undergoing on-pump isolate coronary artery bypass grafting via median sternotomy performed by the same surgical team were included into the study. TTFM was routinely performed for assessment of graft patency during operation after a transit time flow meter became available in our center in February 2006. The last 100 consecutive patients before this date formed the control group (Group A), and the first 100 consecutive patients after this date formed the study group (Group B). Interpretation of the values obtained using the TTFM in Group B patients has allowed us to reach a decision whether or not to revise a graft. Preoperative and postoperative variables of the two groups were compared. The clinical features of control and study groups were comparable. We assessed patency of 303 grafts using TTFM. Revision was required for nine grafts in nine patients based on unsatisfactory TTFM findings. Incidences of overall mortality (p<0.05), peri- or postoperative myocardial infarction (p<0.05) and intraaortic balloon pump insertion (p<0.05) were significantly lower in Group B than Group A. We believe that TTFM seems to be a crucial tool for deciding if a graft is well-functioning or not, and it allows for improvement of graft failure during operation. Our results suggest that detection of graft dysfunction intraoperatively by TTFM improves the surgical outcome.European Journal of Cardio-Thoracic Surgery 08/2007; 32(2):313-8. · 2.55 Impact Factor -
Article: Brachial plexus injury following median sternotomy.
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ABSTRACT: Brachial plexus injury is a rare complication after median sternotomy. We investigated that injury to the brachial plexus was retrospectively assessed in the results of three patients who underwent median sternotomy for open heart surgery. All patients were placed in the hands-up position after right internal jugular vein cannulation, and the internal mammary artery was prepared for all of those. Nerve conduction measurements and electromyography were performed besides neurological examination. Brachial plexus injury was detected in three cases (0.5%) of 575 patients who underwent coronary artery bypass grafting with median sternotomy. The main symptoms were continuous pain, and motor and sensory disturbances at the affected upper extremity (left arm in all cases). The common feature was that in all cases the left internal mammary artery was harvested. While the symptoms were relieved in two patients about six months after the operation, the other one had intractable pain and paresthesia. The most important measure is careful sternal retraction and use of the hands-up position for the low incidence and benign course of brachial plexus problems. Inappropriate sternal retraction during preparation of internal mammary artery should be avoided.Interactive cardiovascular and thoracic surgery 05/2007; 6(2):235-7. -
Article: The effect of surgical treatment for secundum atrial septal defect in patients more than 30 years old.
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ABSTRACT: We prospectively examined whether surgical treatment of secundum atrial septal defects in patients 30 years old improves their early- and mid-term clinical outcomes. Our clinical experience is reviewed to assess the importance of surgical management in elderly patients with atrial septal defect. We analyzed 41 patients older than 30 years of age who underwent surgical correction of a secundum atrial septal defect. To evaluate the effects of surgical treatment, we compared functional capacity, diuretic administration, rhythm status, and echocardiographic parameters of all patients before and after the operation. The median follow-up period was 4.2 years (range, 6 months-7 years). There were no operative deaths. Functional class in most of the patients improved after operation. Two patients reverted to normal sinus rhythm after the operation. There was only one new atrial fibrilation among patients in the postoperative term. Right atrial and right ventricular dimensions and pulmonary artery pressures were significantly decreased, and ejection fractions were significantly increased after the operation. The need for diuretic treatment was decreased after surgical repair. No residual intracardiac shunts were identified during follow-up. There were no cerebrovascular thromboembolic accidents in the early postoperative period. Surgical closure of atrial septal defects in patients over 30 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency. The operation must be performed as soon as possible, even if the symptoms or the hemodynamic impact seem to be minimal.Heart Surgery Forum 02/2007; 10(5):E376-80. · 0.63 Impact Factor -
Article: Pseudoaneurysm of the left coronary ostial anastomoses as a complication of the modified Bentall procedure diagnosed by echocardiography and multislice computed tomography.
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ABSTRACT: We report the case of a patient with a pseudoaneurysm of the left coronary ostial anastomoses diagnosed 6 years after a Bentall procedure with coronary button anastomoses had been performed. Preoperatively, the pseudoaneurysm of the ascending aorta was diagnosed by transesophageal echocardiography and multislice tomography, and the diagnosis was confirmed by surgery. Intraoperatively, the dehiscence of the button anastomosis of the left coronary artery was determined. The operative technique for the repair of the left coronary anastomosis dehiscence was direct closure through a sternotomy using extracorporeal circulation. The patient was discharged on the twelfth day without problems. In conclusion, we demonstrated that the patient with a pseudoaneurysm after a conduit operation of the ascending aorta can be prediagnosed by using echocardiography and multislice tomography.Heart Surgery Forum 02/2007; 10(3):E191-2. · 0.63 Impact Factor -
Article: Massive pulmonary embolism complicated by a patent foramen ovale with straddling thrombus: report of a case.
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ABSTRACT: We report a case of massive right pulmonary embolism with a patent foramen ovale and straddling thrombus, occurring a few days after cesarean section in a 31-year-old woman. Preoperatively, a mass was seen echocardiographically in four cardiac cavities. We performed emergency surgery because of the patient's acute hemodynamic deterioration. Intraoperatively, we found a thrombus entrapped in the patent foramen ovale. Most of the thrombus was floating in the right atrium and a long end was found in the left atrium, in addition to the pulmonary emboli. We removed the thrombus, closed the patent foramen ovale by direct suturing, and performed pulmonary embolectomy. Histological examination confirmed thrombi. Doppler examination of the venous system did not reveal any possible source of the thrombus. The patient is now well and free from recurrence of embolic disease 1 year after surgery. We review the literature on this relatively unusual thromboembolic disease.Surgery Today 02/2006; 36(6):528-33. · 1.22 Impact Factor -
Article: Primary arteriovenous fistulas in the forearm for hemodialysis: effect of miscellaneous factors in fistula patency.
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ABSTRACT: The provision and maintenance of vascular access remains a major cost to end-stage renal failure programs. In addition, vascular access occlusion, results in significant morbidity in hemodialysis patients. Age, gender, diabetes mellitus, malignancy, smoking habits, administration of heparin per hemodialysis session, previous dialysis catheter insertion, number of hemodialysis sessions and location of the fistula may be associated with survival of the primary arteriovenous fistula. We examined the effects of various factors on fistulas in 412 chronic renal insufficiency patients. From 1995 to 2004, 412 arteriovenous fistulas were created by the Department of Cardiovascular Surgery at the Medical Faculty of Atatürk University for hemodialysis. The mean age of the patients was 45 years (range 6 to 62 years). We evaluated the effects of various factors for patency rates in the patients who had primary arteriovenous fistulas. Primary patency was defined as the duration of fistula patency without revision. Twenty-eight patients (6.7%) with ischemic cardiac disease did not require surgical interference. Analyzed data were age, gender, smoking habits, diabetes mellitus, malignant neoplasm, previous dialysis catheter insertion, number of hemodialysis sessions, and fistula location. In 298 patients, where lower-arm radiocephalic fistulas were created, the fistula patency was 74.1%, 64.2%, 49.8%, 33.7%, and 4.1% after 1, 2, 3, 4, and 5 years, respectively, in the other 114 patients, where upper-arm fistulas were created, these rates were 84.0%, 72.2%, 53.3%, 39.8%, and 12.3%, respectively. There was no significantly difference between the upper-arm fistulas and the lower-arm fistulas statistically (p = 0.069). Factors affecting the primary patency of arteriovenous fistulas were diabetes mellitus (p = 0.0001), hemodialysis counts > or =3 per week (p < 0.0005), presence of malignancy (p < 0.0005), previous catheter insertion (p < 0.0007), and administration of heparin per hemodialysis session (p = 0.0008). While primary arteriovenous fistula patency was shortened in chronic renal insufficiency patients with diabetes mellitus, presence of malignancy, and previous catheter insertion, patency was longer in patients with heparin used for hemodialysis and hemodialysis count per week (> or =3).Renal Failure 01/2006; 28(4):275-81. · 0.82 Impact Factor -
Article: Surgical treatment in a patient with multiple systemic complications of prosthetic aortic valve endocarditis: case report.
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ABSTRACT: A 31-year-old woman who had undergone aortic and mitral valve replacement 1 year previously was hospitalized with suspected prosthetic valve endocarditis. Freestyle stentless aortic xenograft was successfully replaced using freestanding total aortic root replacement techniques at the left ventricular outflow tract position, and aorta-to-right coronary artery bypass was also applied with a saphenous vein graft. The patient developed multiple systemic problems during the preoperative and postoperative periods and was successfully treated with intensive interventions. She was discharged at the postoperative fourth month, and the following 28 months were uneventful.Heart Surgery Forum 02/2005; 8(1):E52-4. · 0.63 Impact Factor -
Article: A nail in the heart.
The Annals of thoracic surgery 08/2004; 78(1):e15. · 3.74 Impact Factor -
Article: Left ventricular pseudoaneurysm after myocardial infarction.
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ABSTRACT: In this report, a case of a left ventricular (LV) pseudoaneurysm due to a previous myocardial infarction, which was repaired successfully, is described. A 62-year-old man, with a history of acute anterior wall myocardial infarction 6 months previously, was admitted with the complaints of acute dyspnea and palpitation. Echocardiography revealed an LV aneurysm, and ventriculography showed ventricular dysfunction and an LV pseudoaneurysm. Coronary angiography showed total occlusion of the proximal segment of the left anterior descending artery with a very thin lumen and insufficient retrograde filling. Under cardiopulmonary bypass and beating heart, the pseudoaneurysm was resected and the defect on the ventricular free wall was closed by the remodeling ventriculoplasty method of Dor. Histopathologic examination of the resected material confirmed the diagnosis of pseudoaneurysm. The postoperative course of our patient was uneventful. He was discharged on the ninth postoperative day.Heart and Vessels 08/2003; 18(3):160-2. · 2.05 Impact Factor -
Article: Mitral valve replacement and tricuspid annuloplasty via right mini-thoracotomy in a patient with tracheostomy.
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ABSTRACT: This report describes our experience in performing mitral valve replacement and tricuspid annuloplasty via a right mini-thoracotomy in a patient with tracheostomy. A 24-year-old woman was admitted with shortness of breath and palpitations. She had subglottic tracheal stenosis and tracheostomy due to tracheal intubation of long duration. Echocardiography revealed chronic severe mitral and tricuspid valve regurgitation. We planned to perform at first the cardiac, and then the tracheal operation, because her left ventricular function was worsening. To eliminate the potential complications of sternotomy in patients with tracheostomy, we used right mini-thoracotomy. We performed mechanical mitral valve replacement for the mitral valve and De Vega annuloplasty for the tricuspid valve. The patient was transferred to the tracheal surgery clinic after the 20th day. Tracheal resection and anastomosis were performed in this department. Three months later, the patient was asymptomatic. We believe that the right mini-thoracotomy approach is a good technique for mitral valve replacement in patients with tracheostomy.Heart and Vessels 06/2003; 18(2):103-4. · 2.05 Impact Factor -
Article: Involvement of the coronary artery in a patient with thromboangiitis obliterans. A case report.
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ABSTRACT: We report a case of coronary artery bypass grafting (CABG) using the left internal mammary artery (LIMA) and a saphenous vein graft in a 36-year-old man with Buerger's disease. He was hospitalized in the coronary intensive care unit with a diagnosis of acute myocardial infarction. His coronary angiography showed total occlusion of the proximal segment of the left anterior descending artery (LAD) and right coronary artery. Left ventricular dysfunction was detected by ventriculography. The patient had undergone bilateral sympathectomy of the lumbar branches for distal arterial occlusions due to thromboangiitis obliterans 12 years previously. Under cardiopulmonary bypass and aortic cross-clamping, we performed endarterectomy and a complex bypass procedure to LAD. Aorta-right coronary artery bypass was also applied. A histopathological study of an endarterectomy specimen showed characteristic features of thromboangiitis obliterans. The postoperative course was uneventful and the patient was discharged on the ninth postoperative day.Heart and Vessels 08/2002; 16(5):201-3. · 2.05 Impact Factor -
Article: Arterial embolism caused by a ruptured hydatid cyst in the heart: report of a case.
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ABSTRACT: Cardiac hydatid cysts are extremely rare and, although patients may remain asymptomatic for many years or have only minor nonspecific symptoms, they are associated with life-threatening complications. We report the case of a 32-year-old woman with an acute arterial embolism caused by a ruptured hydatid cyst in the heart. An emergency operation revealed that the embolism originated from the left cardiac chamber caused by a cyst in the left ventricle. There were also three cystic lesions in the right lung. The patient underwent surgery to remove the hydatid cysts from the right lung on the 13th day after the first operation. Her postoperative course was uneventful and she was discharged from hospital on the 27th day after admission.Surgery Today 02/2002; 32(11):989-91. · 1.22 Impact Factor -
Article: Diagnosis and Treatment of Peripheric Arterial Pseudoaneurysms: Evaluation of the 34 Cases
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ABSTRACT: The increasing number of invasive cardiac centers and interventional diagnostic and therapeutic procedures leads to an increased incidence of iatrogenic or traumatic false aneurysms (pseudoaneurysms) in the extremity arteries. Surgical treatment can be easily performed and has a low risk, but without treatment rupture and embolization can be fatal. In this study, we examined 34 pseudoaneurysm patients operated on between 1999–2006 in Atatürk University School of Medicine Cardiovascular Surgery Clinic. Nineteen patients (55.8%) were male and 15 (44.2%) were female. The mean age was 47.9±5.81 years (range, 14 to 77). The most frequent signs were pulsatil hematoma and thrill. The diganosis of the pseudoaneurysm was established with physical examination, coloured Doppler ultrasonography, and magnetic resonance imaging angiography. The femoral superficial artery was the most common site of presentation with 73.6%. The most important etiologic factor was the arterial puncture aimed diagnosis. In 23 patients (67.6%) the pseudoaneurysmal sac was opened and resected, and after the drainage of the hematoma the puncture point was primarily sutured. In the other patients the continuity of the arterial flow was restored by end-to end anastomoses or graft interposition. The amputation and mortality were not detected. Ischemic changes in the involved extremities have not occured. In this study, we present our clinical experiences relation to arterial pseudoaneurysms. -
Article: Management of carotid body tumors and familial paragangliomas: review of 30 years' experience.
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ABSTRACT: Carotid body tumors (CBTs), especially familial paragangliomas, are rare benign neoplasms, accounting for <0.5% of all tumors; and they are the most common extra-adrenal paraganglioma. In this study, CBTs were clinically suspected in 31 patients but diagnosed by histopathology in 28 between 1977 and 2007 at our department. All but one was operated upon. The ages of the 30 surgically treated patients ranged 17-73 years. A mass in the neck was the common symptom in all patients. Two of the 28 patients with CBTs had a familial paraganglioma history of CBT. Twenty-eight of these 30 surgically treated patients had confirmed CBT by histopathology; the diagnoses of other two patients were neurofibroma in one and tuberculosis lymphadenitis in one. These two patients were excluded from the study. CBTs were resected without a shunt procedure. UltraCision was used in five patients for tumor resection; the surgical results of these patients were excellent (easy dissection, minimal hemorrhage and time operation). Twenty patients underwent total resection, six had resection and saphenous vein interposition, one had partial resection, and one had carotid artery ligation with no resultant neurological deficit. One case of hypoglossal paralysis and one benign recurrence were detected. No mortality or malignant course was observed. CBTs are infrequent neoplasms; their surgical treatment is highly dependent on the ability and experience of the surgeon. The diagnostic and therapeutic relevance reside in making a timely diagnosis to propose a surgical treatment aimed at preventing complications and neurological damage. Surgical resection is usually definitive therapy for these lesions.Annals of Vascular Surgery 23(5):616-20. · 1.03 Impact Factor
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2002–2012
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Ataturk University
Erzurum, Erzurum, Turkey
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