Youn-Hee Choi

Kyungpook National University, Daikyū, Daegu, South Korea

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Publications (40)45.15 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: The prevalence of metabolic syndrome (MetS) increases even in adolescents. The evidence that MetS is associated with the periodontal diseases in adolescent has been understudied. Therefore, our aim was to assess the association between MetS parameters and gingivitis in adolescents. A total of 941 participants (590 boys, 351 girls), aged 12-18 years was selected from the Fourth Korea National Health and Nutrition Examination Survey, a cross-sectional and nationally representative survey, who have had information on waist circumference, blood pressure, serum triglyceride, high-density lipoprotein (HDL) cholesterol, and the fasting blood sugar and community periodontal Index (CPI). The number of positive parameters of MetS showed significant positive correlation with gingivitis; adjusted and crude ORs with one positive parameters of MetS were 1.92(95% CI: 1.21-3.04) and 1.88(95% CI: 1.28-2.76), respectively. And adjusted OR with three or more positive parameters of MetS was 3.29 (95% CI: 1.24-8.71). Among five parameters of MetS, Low HDL-cholesterol showed significant association with gingivitis (crude OR 2.12, 95% CI 1.20-3.73; adjusted OR 1.96, 95% CI 1.24-3.12). Having more positive parameters of MetS and positive HDL-cholesterol parameter had an independent relationship with the prevalence of gingivitis, which may be determinants for the future periodontal diseases even in adolescents This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
    Journal Of Clinical Periodontology 12/2014; · 3.61 Impact Factor
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    ABSTRACT: Background: Periodontitis is a result of a complex biological alteration of the periodontal microenvironment, and a distributional shift of key periodontal pathogens. Metabolic syndrome (MetS), a complex cluster of cardiovascular risk factors, has been linked to periodontal diseases; however the contribution of periodontal bacteria to systemic conditions remains unclear. Methods: The study population comprised of 7848 US adults who participated in an interview, clinical, oral health examination, and had serum IgG titers measured against 19 periodontal bacteria as part of the third National Health and Nutritional Examination survey (NHANES III). The z-scores antibody titers were clustered into 4 mutually exclusive groups and named after Socransky's classification of periodontal bacteria (Orange-Red, Red-Green, Yellow-Orange, and Orange-Blue). Survey logistic regression was used to investigate the independent associations between the cluster scores, and MetS and each component including hypertension, hypertriglyceridemia, low HDL-cholesterol, central obesity, and elevated fasting glucose. Results The Orange-Red cluster score (that included P. gingivalis and Prevotella sps) was positively associated [OR: 1·067 (1·02-1·12)] and Orange-Blue cluster score (which included A. naeslundii and E. nodatum) inversely associated [OR= 0·93 (0·88-0·97)] with elevated fasting glucose (≥110 mg/dl) after adjusted for clusters and potential confounders. Neither MetS nor its other remaining MetS components were associated with a particular cluster score. Conclusion: The associations between specific antibody clusters (Orange-Red and Orange-Blue) against periodontal bacteria and elevated plasma glucose were in qualitatively opposite directions after multivariable adjustment in a large, adult population. The periodontal bacterial profile was not found associated with metabolic control other than very moderate association with elevated plasma glucose.
    Journal of Periodontology 11/2014; · 2.57 Impact Factor
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    ABSTRACT: Background: Serum C-reactive protein (CRP) is elevated in both periodontitis and type 2 diabetes mellitus through inflammation. Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis have been found in periodontal pockets in diabetic patients. We examined effect modification by examining the extent to which the associations between periodontitis and hyperglycemia were different by levels of serum CRP and periodontal pathogens. Methods: Blood samples with plasma was evaluated for IgG antibodies, CRP, and fasting glucose from 5,731 participants ≥19 years old receiving oral examination and providing other health-related data from National Health and Nutrition Examination Survey III. The study participants were classified into quartiles of probing depth (PD) and clinical attachment (CA) loss. The first quartile was the reference. Logistic regression models with SAS survey procedures were used to explore the roles of inflammation levels from serum CRP and periodontal pathogens on the relations between periodontitis including PD and clinical attachment loss and hyperglycemia, and their joint associations with interaction terms. Results: Stronger associations between PD and diabetes existed in people having elevated CRP and titers for P. gingivalis; odds ratios comparing extreme quartiles of PD were 1.31 and 3.40 in the groups with low and high CRP respectively, and 1.28 and 2.96 in groups with low and high titers for P. gingivalis respectively. The joint association patterns were similar for CA loss and diabetes. Conclusion: The strengths of association between periodontitis and diabetes were stronger in people having elevated serum CRP and P. gingivalis titers. This may suggest that chronic inflammatory condition could increase the impact of periodontitis on hyperglycemic status.
    Journal of Periodontology 01/2014; · 2.57 Impact Factor
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    ABSTRACT: The purpose of this study was to develop a self-administered questionnaire survey to determine its validity and reliability as well as to improve the instructions for measurement of periodontal disease during oral examination for reliably calculating the prevalence of periodontal disease.
    Journal of Korean Academy of Oral Health. 01/2014; 38(3):170.
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    ABSTRACT: Purpose: The effects of an oral hygienic care program (OHCP) have been reported in several diseases. However, no study exists investigating the influence of an OHCP on stroke patients or patients in the intensive care unit (ICU) has been reported, thus we sought to investigate the potential effect of an OHCP. Materials and Methods: Fifty-six consecutive stroke patients who were admitted to the ICU were randomly assigned to two groups: the intervention (29 patients) and control groups (27 patients). The OHCP included tooth brushing with an inter-dental brush and tongue cleaner and cleaning with chlorhexidine was administered to patients by one dentist once per day during admission in the ICU (mean, 2.2 weeks). The plague index, gingival index, clinical attachment loss, and colonization degree of candida albicans were assessed. Results: After OHCP, the plaque index, gingival index, and colonization degree of candida albicans in saliva showed a significant decrease in the intervention group compared to those of the control group (p<0.05). However, no significant difference was observed in clinical attachment loss and the colonization degree of candida albicans on the tongue (p>0.05). Conclusion: Our OHCP was effective in improving the oral hygienic status and periodontal health of stroke patients during their stay in the ICU. Therefore, we recommend administration of the OHCP for stroke patients during their stay in the ICU.
    Yonsei medical journal 01/2014; 55(1):240-6. · 0.77 Impact Factor
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    ABSTRACT: Rheumatoid arthritis (RA) has been associated with systemic diseases, such as periodontal diseases. Periodontal diseases and RA appear to share many pathologic features. The etiology of the two diseases may differ, but they share similar pathological characteristics. Therefore, the aim of this study was to evaluate the correlation between RA and periodontal diseases.
    Journal of Korean Academy of Oral Health. 01/2014; 38(4):232.
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    ABSTRACT: Evidence consistently shows that diabetes is a risk factor for increased prevalence of gingivitis and periodontitis. But there is a controversy about the relationship between diabetes related factors and periodontal health. The aim of the present study is to explore the relationship between diabetes related factors such as glycosylated hemoglobin, fasting blood glucose, duration of diabetes and compliance to diabetes self management and periodontal health status. Periodontal health of 125 participants with type-2 diabetes mellitus was measured by the number of missing teeth, community periodontal index (CPI), Russell's periodontal index and papillary bleeding index. Information on sociodemographic factors, oral hygiene behavior, duration and compliance to self management of diabetes, levels of glycosylated hemoglobin(HbA1c) and fasting blood glucose(FBG) were collected by interview and hospital medical records. Statistically, independent t-test, an analysis of variance (ANOVA), chi-squared test and multiple regression analyses were used to assess the association between diabetes-related factors and periodontal health. Periodontal parameters including the number of missing teeth and papillary bleeding index were significantly influenced by duration of diabetes, FBG and compliance to self management of diabetes. CPI was significantly influenced by duration of diabetes, FBG and HbA1C. And Russell's periodontal index was significantly influenced by duration of diabetes, FBG, HbA1C and compliance to self management of diabetes. Results of multiple linear regression analysis showed that the duration of diabetes showed significant positive correlation with all of the periodontal health parameters, except for missing teeth. HbA1c was correlated with Russell's periodontal and papillary bleeding index. FBG and compliance to self management of diabetes were correlated with missing teeth and papillary bleeding index respectively. Diabetes-related factors such as duration of diabetes, FBG, HbA1c and compliance to self management of diabetes were significantly correlated with periodontal health among individuals with type-2 diabetes.
    BMC Oral Health 11/2013; 13(1):64. · 1.15 Impact Factor
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    ABSTRACT: The aim of this study was to investigate the relationship between the duration and number of components of metabolic syndrome and periodontal disease among rural elderly in Korea over 60 years old. This longitudinal study consisted of 399 participants who underwent regular health examinations at Seongju-gun Public Health Center from 2000 to 2007. The components of metabolic syndrome (diabetes mellitus, hypertension, obesity, and hypercholesterolemia) were evaluated from clinical records of Seongju-gun Public Health Center, which were recorded from 2000 to 2007, and periodontal examination by Community Periodontal Index, recorded from 2006 to 2007. Participants suffering from longer durations of diabetes mellitus, hypertension, and obesity were more likely to have periodontal disease. Individuals with a greater number of metabolic syndrome components were more likely to have periodontal disease. Older rural Koreans with components of metabolic syndrome have unmet periodontal treatment needs. Medical and dental professionals need to coordinated systemic and oral care for these people.
    Archives of gerontology and geriatrics 09/2013; · 1.36 Impact Factor
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    ABSTRACT: For the first nationwide representative survey on the environmental health of children and adolescents in Korea, we designed the Korean Environmental Health Survey in Children and Adolescents (KorEHS-C) as a two-phase survey and planned a sampling strategy that would represent the whole population of Korean children and adolescents, based on the school unit for the 6-19 years age group and the household unit for the 5 years or less age group. A pilot study for 351 children and adolescents aged 6 to 19 years in elementary, middle, and high school of two cities was performed to validate several measurement methods and tools, as well as to test their feasibility, and to elaborate the protocols used throughout the survey process. Selected exposure biomarkers, i.e., lead, mercury, cadmium in blood, and bisphenol A, metabolites of diethylhexyl phthalate and di-n-butyl phthalate and cotinine in urine were analyzed. We found that the levels of blood mercury (Median: 1.7 ug/L) and cadmium (Median: 0.30 ug/L) were much higher than those of subjects in Germany and the US, while metabolites of phthalates and bisphenol A showed similar levels and tendencies by age; the highest levels of phthalate metabolites and bisphenol A occurred in the youngest group of children. Specific investigations to elucidate the exposure pathways of major environmental exposure need to be conducted, and the KorEHS-C should cover as many potential environmental hazards as possible.
    International journal of hygiene and environmental health 06/2013; · 2.64 Impact Factor
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    ABSTRACT: Objectives : The aim of this study was to evaluate the relationship between the hand washing management and tooth brushing frequency. Methods : The subjects in this study were 7,285 adults who were selected from the third-year(2009) raw data of the fourth national health & nutrition survey. Results : The mean frequency of daily toothbrushing was 3.35. Increases the frequency of both toothbrushing and hand washing with higher grade class. The higher the tooth brushing frequency, the intention of hand washing management at school and home was more increased. Conclusions : This study can contribute to the general health and oral health promotion.
    Journal of Korean society of Dental Hygiene. 02/2013; 13(1).
  • Journal of Korean Academy of Oral Health. 01/2013; 37(3):147.
  • Journal of Korean Academy of Oral Health. 01/2013; 37(3):126.
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    ABSTRACT: Sensitization to allergens is considered as major mechanism of allergy and related to the development of allergic diseases. The objective of this study was to evaluate overall sensitization rates of inhalant allergens and the relationship between polysensitization and prevalence of allergic diseases in children and adolescents.
    Allergy Asthma & Respiratory Disease. 01/2013; 1(1):41.
  • Journal of Korean Academy of Oral Health. 01/2013; 37(1):47.
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    ABSTRACT: Little is known about the effects of socio-environmental factors on dental caries in different demographic situations in Asian populations. We investigated whether the nature of the association between regional socio-economic context and dental caries experience differed according to gender and age groups in Korean adults. We obtained a linked data set containing individual information from the 2000 Korean National Oral Health Survey and regional information from the "Major statistical indices of Si-Gun-Gu" (city-county-ward), published by the Korean Statistical Office. We stratified participants into women and men and into four 10-year-interval age groups (19-34, 35-44, 45-54, and 55-64 years) and analysed the linked data using a multilevel analysis. In total, 5,259 individuals were included in the final study population. Regional socio-economic context was significantly associated with dental caries experience in men, but not in women. The patterns of the association between regional contextual variables and dental caries experience differed among age groups. People 35-44 years of age living in areas less dependent on the manufacturing industry and those 45-54 years of age living in areas where local government was relatively poor were more prone to have caries experience. The results of this study indicated that socio-economic factors affecting residents' dental health status may operate through different mechanisms or degrees according to geographic location, suggesting that some gender- and age-defined subgroups may be likely to benefit from different types of intervention, including the development of specific health policies.
    International Journal of Health Geographics 07/2012; 11:30. · 2.62 Impact Factor
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    ABSTRACT: Bisphenol A (BPA)-based dental composites have commonly been used to fill dental cavities or seal pits and fissures on teeth. However, epidemiological evidence with regard to the BPA exposure from dental composites among children has rarely been reported. This study investigated whether there is a relationship between the BPA concentration in urine and the presence of composite restorations and sealants among South Korean children. Oral examinations and urine sample analyses were conducted on a total of 495 children aged 8-9 years. We classified the participants into four groups by the number of resin composites and sealant surfaces (0, 1-5, 6-10 and 11+). BPA concentrations in urine were higher in children with 11 or more surfaces restored with sealants and resin composites than in those with zero restored surfaces, although no difference was seen in the group with 1-10 surfaces. After adjusting for gender and age, the urinary BPA concentration in children with 11 or more resin composite surfaces was 2.67 μg/g creatinine, which was higher than the concentration found in those with no filling surfaces (P < 0.01). Having many dental composite filling surfaces on teeth may increase the urinary BPA concentration in children.
    International Dental Journal 04/2012; 62(2):65-9. · 1.20 Impact Factor
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    ABSTRACT: Streptococcus mutans (S. mutans) is the major causative bacteria in dental caries. Xylitol is an effective anticarious natural sugar substitute by inhibiting the virulence of S. mutans. However, long-term xylitol consumption leads to the emergence of the xylitol-resistant S. mutans (XR). The aim of this study is to analyze the difference of gene expression profile of xylitol-sensitive S. mutans (XS) and XR in 0.5% glucose containing TYE media, using a DNA chip.
    Journal of Korean Academy of Oral Health. 01/2012; 36(4):251.
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    ABSTRACT: Periodontal treatment is associated with lower hemoglobin A1c in individuals with diabetes, but the relationship between oral hygiene practices and A1c among youth with diabetes is understudied. This study evaluates the cross-sectional relationships among oral health habits, reported oral conditions, and A1c and control of diabetes among a subset of youth with diabetes enrolled in the SEARCH for Diabetes in Youth study in South Carolina. Oral hygiene practices were determined by questionnaire, and periodontal bone loss was defined as alveolar bone loss ≥3 mm on ≥1 permanent tooth site on preexisting bitewing radiographs. A1c was considered controlled if individuals were aged ≤6 years with A1c <8.5%; aged 7 to 11 years with A1c <8.0%; aged 12 to 18 years with A1c <7.5%; and aged ≥19 years with A1c <7.0%. Among 155 participants, 68% brushed their teeth no less than once daily, 84% flossed, and 70% rinsed, respectively, less than once a week. Diabetes control was associated with toothbrushing (≥1 time daily [odds ratio (OR) = 3.10; 95% confidence interval (CI) = 1.26 to 7.62] and using mouthrinse at least once weekly (OR = 3.33; 95% CI = 1.30 to 8.54) after multivariate adjustment. Periodontal bone loss was three times more common among those with dry mouth (OR = 3.05; 95% CI = 1.07 to 8.70). Clinicians should be aware that children with diabetes tend to have poor oral hygiene practices. Dry mouth may indicate periodontal bone loss in children with diabetes.
    Journal of Periodontology 12/2011; 83(7):856-63. · 2.57 Impact Factor
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    ABSTRACT: The aim of this study was to investigate the capacity of the xylitol-sensitive(Xs) and xylitol-resistant(Xr) S. mutans to induce dental caries in the presence of various carbohydrate. S. mutans KCTC3065 was cultured with 0.4% glucose and 1% xylitol in TYE medium for 30 days at , 10% to form Xr S. mutans. Both Xs and Xr strains were cultured in four different carbohydrate environments; 0.5% glucose containing basal culture TYE medium(G-TYE), G-TYE plus 0.5% sucorse, G-TYE plus 0.5% fructose, G-TYE plus 0.5% maltose. Then cell growth, acid production, and extracellular polysaccharides synthesis were analyzed. The final growth level and extracellular polysaccharides contents in the Xr strain were significantly lower than in the Xs strain in all carbohydrates except fructose. While, acid production was no significantly difference between Xs and Xr strain. These results indicate that the virulence of Xr strains is significantly lower than that of Xs strains, which supports Xr strains may be less cariogenic than Xs strains.
    Journal of the Korea Academia-Industrial cooperation Society. 10/2011; 12(10).
  • Youn-Hee Choi, Sang Gyu Lee
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    ABSTRACT: Recent thinking about the role of regional socioeconomic context in generating health inequalities has argued for the collection of true 'area' data that accurately reflect the characteristics of a region. We investigated whether a range of attributes of regional environments, constructed from factor analysis of various regional socioeconomic indices, is associated with the dental caries experience of adults, and whether the nature of this association changes according to age. A linked data set comprising information on 6,402 individuals from the Korean National Oral Health Survey of 2000 and regional information from 118 districts where our study population lived, were examined using multilevel analysis. The regional contextual variables, 'density of service and medical facilities' and 'dependence on manufacturing industry', were negatively associated with dental caries experience after controlling for individual characteristics, and these associations differed by age groups, especially in the older age group. Our findings suggest that hypotheses about specific chains of causation which might link service affluence or industrialization with dental caries need to be investigated further using more detailed indices.
    European Journal Of Oral Sciences 08/2011; 119(4):294-300. · 1.73 Impact Factor

Publication Stats

89 Citations
45.15 Total Impact Points

Institutions

  • 2007–2014
    • Kyungpook National University
      • Department of Preventive Dentistry
      Daikyū, Daegu, South Korea
  • 2013
    • Yeungnam University
      • Department of Preventive Medicine and Public Health
      Daikyū, Daegu, South Korea
  • 2012
    • Dankook University
      • College of Medicine
      Yŏng-dong, North Chungcheong, South Korea
  • 2011
    • University of South Carolina
      • Department of Epidemiology & Biostatistics
      Columbia, SC, United States
  • 2005
    • Pusan National University
      Tsau-liang-hai, Busan, South Korea