[show abstract][hide abstract] ABSTRACT: ABSTRACT
Objective: In this study our aim is to determine the differences in HRTII parameters of patients who had glaucoma suspected optic discs and increased intraocular pressure in follow up.
Methods: Fifty-eight eyes of 29 (18 female and 11 male) with a mean age of 49.30 ±8.40 years that were previously under follow-up due to glaucoma
suspect in respect to the appearance of glaucomatous cupping, who have HRTII examination, normal CCT, normal visual field and have increased IOP
in follow-up; and control group with 32 eyes of 16 (10 female, 6 male) with a mean age of 53.20±7.40 years with physiological optic discs but with HRTII
examination taken in routine examination included in the study. The first and the last IOP, the first and the last HRTII global values, age and sexes were
Results: The follow up time of patients those with increased IOP was 9.10±3.69 years and the control group’s was 10.13±0.62 years. The difference
between the last and the first measured IOP of the study group was statistically significantly higher than the control group’s (p<0.05). There was no difference in age, sex distribution, disc areas and between the first and the last examination time interval (p>0.05). In our study global optic disc variables
were found to change with same ratio over time both in study and the control group in means of cup area, c/d area ratio, and rim area. There was no
difference in HRTII parameters; cup area, cup volume, cup / disc area ratio, mean cup depth and maximum cup depth between the first and the last
examinations in the study group but these measured results are statistically higher in baseline when compared with the control group.
Conclusion: As a conclusion, one of the major challenges in the management of glaucoma is the early detection of the disease. Although it is a small
scale, this study is the first that has shown optic disc structural analysis with HRTII in a glaucoma suspect population before and after IOP increases.
Our study has shown that especially baseline cup area, mean cup depth and maximum cup depth may be a risk factor for IOP increase in follow up.
Thus, detecting a glaucomatous change in the optic nerve head parameters before IOP increase may be a predictor of future ocular hypertension and
primary open angle glaucoma patients. More studies in large scales have to be done for support of our findings. (JAREM 2013; 3: 69-73)
Key Words: Glaucoma, HRTII, intraocular pressure, ocular hypertension
Journal Of Academic Research In Medicine. 09/2013; 2013(3):69-73.
[show abstract][hide abstract] ABSTRACT: Aims: Purpose of this study is to compare corneal reflex value measurements performed by the Plusoptix S08 photo-screener between anisometropic non–strabismic amblyopic children and non-amblyopic children. Study Design: This is a randomized and controlled prospective study. Place and Duration of Study: Department of Ophthalmology, Medical Faculty of Istanbul Medipol University between September 2012 and December 2012. Methodology: Corneal reflex values of 39 amblyopic non-strabismic children and 28 normal children were compared after complete ophthalmoscopic examination by the same examiner. Only patients with anisometropic amblyopia without strabismus were included in the study group and only non-amblyopic children were included in the control group. Results: There was no statistical significance between the study and the control group in means of age (p=0.100) and sex distribution (p=0.818). Corneal reflex values of the amblyopic eyes was 3.8±3.2 degrees and corneal reflex values of normal eyes was 2.4±4.1 degrees. There was no statistical significance between study and control group in means of corneal reflex values (p=0.127). Conclusion: Although Plusoptix has proved to be a reliable screener in terms of measurement of refraction, we did not know whether the corneal reflex value was also a reliable screening value, because there is no research about this value in the literature. According to the current literature this is the first research examining the corneal light reflex reliability of a Plusoptix S08 photo-screener and, in light of our results, the corneal reflex value of Plusoptix S08 is not a reliable tool for the screening of amblyogenic risk factors in non-strabismic children. - See more at: http://www.sciencedomain.org/abstract.php?iid=199&id=23&aid=1685#.Ueja9tJA2So
Ophthalmology Research: An International Journal. 08/2013; 1(1).
[show abstract][hide abstract] ABSTRACT: To evaluate the effectiveness of an intravitreal bevacizumab injection on retinal neovascularization and diabetic macular edema (DME) refractory to laser photocoagulation therapy. Thirty-four eyes of 22 patients with proliferative diabetic retinopathy and DME refractory to laser photocoagulation therapy received an intravitreal injection of 1.25 mg/0.05 ml of bevazicumab. Changes in mean best-corrected visual acuity (BCVA), central macular thickness (CMT), regression of neovascularization over time, and correlation between BCVA and CMT were evaluated. Follow-up visits were at weeks 1, 2 and 4 and months 3 and 6. Mean BCVA was significantly better than baseline only at week 2 (P = 0.036). Mean CMT decreased significantly from baseline at weeks 1, 2, and 4 (P = 0.001). At months 3 and 6, mean CMT increased, albeit insignificantly (P = 0.804 and P = 1.0). The decrease in fluorescein leakage was moderate in all eyes at the end of week 1. At week 2, there was total resolution of fluorescein leakage in 24 (70.5%) eyes and moderate resolution in 10 (29.5%) eyes. At the end of month 3, the fluorescein leakage was fully resolved in 5 (14.7%) eyes, moderately resolved in 24 (70.5%) eyes, and was similar to baseline in 5 (14.7%) eyes. At month 6, the fluorescein leakage was fully resolved in 3 (8.8%) eyes, moderately resolved in 20 (58.8%) eyes, and was similar to baseline in 11 (32.4%) eyes. A moderate but insignificant negative correlation was found between visual acuity and CMT (P > 0.05). Persistence or recurrence of neovascular tissue after panretinal photocoagulation may be attributed to the production of vascular endothelial growth factor by the residual ischemic retina, which also results in persistent or recurrent DME despite macular grid photocoagulation.
International Ophthalmology 10/2010; 30(6):697-702.
[show abstract][hide abstract] ABSTRACT: A 48-year-old male had been diagnosed with Behcet's disease two years previously. During the remission period a sudden decrease in visual acuity developed in the right eye. Visual acuity in the right eye was 1/10. Relative afferent pupillary defect and impaired colour vision was detected. The anterior segment was normal. Fundus examination revealed right optic disk swelling. Neurological examination and magnetic resonance imaging were normal. Mega dose steroid therapy was initiated. Visual acuity began to improve after the third day and was 9/10 at the end of the first month of the therapy.
[show abstract][hide abstract] ABSTRACT: To describe optical coherence tomography findings in patients with late solar retinopathy and their association with visual loss.
Twenty-one eyes of 21 patients who had a history of watching a solar eclipse in 1999 with or without visual loss were evaluated with colored and red-free fundus photography and optical coherence tomography analysis using the macular thickness protocol.
Ten of the eyes (47.6%) had no visual acuity loss and 11 eyes (52.4%) had visual acuities ranging from 0.3 to 0.8. There was a strong correlation between central foveal thickness and visual acuity. Empty spaces involving the full thickness of the photoreceptor layer band of the entire fovea were observed in 10 eyes and found to be associated with visual acuity loss. Signal defects in the outer and inner segments of the photoreceptors were identified in 12 and 15 eyes, respectively, and were not associated with visual acuity loss.
Decreased central foveal thickness and full-thickness empty spaces beneath the fovea in optical coherence tomography analysis can be associated with permanent visual acuity loss in patients with a history of watching a solar eclipse.
[show abstract][hide abstract] ABSTRACT: We report a case of HELLP syndrome with bilateral decreased vision at 25 weeks' gestation. Fundus examination revealed serous retinal detachment involving the macula. Systemic steroid and oral dorzolamide therapy was initiated and visual acuity improved. At 2 months, peripheral localized tractional retinal detachment was present in the left eye and argon laser photocoagulation was performed. Macular elevation did not resolve; therefore, in the right eye intravitreal triamcinolone acetonide injection was performed.
Annals of Ophthalmology 10/2007; 39(3):261-3. · 0.16 Impact Factor
[show abstract][hide abstract] ABSTRACT: To determine the incidence and risk factors for cystoid macular edema (CME) after phacoemulsification surgery and its effect on visual acuity.
This prospective study evaluated 98 eyes of 98 patients (43 women) with a mean (SD) age of 61.8 (11.3) years. Phacoemulsification was performed with temporal clear corneal incision and implantation of foldable hydrophilic acrylic intraocular lens in the bag. Postoperative visits were on day 1, week 1, and at 1, 3, and 6 months. In addition, at week 10 all patients had fundus fluorescein angiography, and presence of CME was determined. Age, sex, iris colour, pseudoexfoliation, type of cataract, phaco time, status of the posterior vitreous, iris trauma, severity of anterior chamber reaction, and visual acuities were evaluated.
No major intraoperative complications occurred. Twenty-five (25.5%) eyes were CME(+), and 73 (74.4%) eyes were CME(-). CME occurred in 70% of patients with iris trauma and 20.5% of patients with no iris trauma. CME was more common in patients who had postoperative anterior chamber inflammation of 2+ or more than in patients with less inflammation (43.2% vs. 11.5%). Complete posterior vitreous detachment had some apparent protective effect against CME development. The mean visual acuities of CME(+) patients were lower than those of CME(-) patients in all postoperative periods. The difference was significant in the third month (p < 0.05).
CME after phacoemulsification was associated with iris trauma and severe postoperative inflammation. Complete posterior vitreous detachment had some apparent protective effect against CME development. CME may be associated with decreased visual acuity.
Canadian Journal of Ophthalmology 01/2007; 41(6):699-703. · 1.15 Impact Factor
[show abstract][hide abstract] ABSTRACT: To evaluate the effect of sodium hyaluronate on the early complications of trabeculectomy.
In this prospective study, trabeculectomy was performed in 51 eyes of 51 patients with different types of glaucoma. Patients were divided into two groups randomly. In 24 eyes (study group) sodium hyaluronate was injected into the anterior chamber after suturing the scleral flap. In the remaining 27 eyes (control group) only balanced salt solution was injected. Visual acuities, intraocular pressures and early complications were evaluated.
Preoperative mean intraocular pressures were similar in the two groups (34.5 +/- 18.7 mmHg in the study group and 37.2 +/- 18.1 mmHg in the control group). In the first postoperative day mean intraocular pressure difference was significant (16.8 +/- 7.1 mmHg in the study group and 9.0 +/- 6.6 mmHg in the control group, P < 0.01). There was significant difference in occurrence of hypotony (8.3% study vs. 40.7% control), anterior chamber shallowing (8.3% study vs. 37% control) and choroidal detachment (none in study vs. 33.3% control) between the two groups (P < 0.01). Early intraocular pressure peak, occurred more common in the study group (20.8%) than in the control group (11.1%), but the difference was not significant (P > 0.01). Hyphema occurred in two (8.3%) eyes in the study group, and three (11.1%) in the control group. This was not significant (P > 0.01). The clearance time of blood from the anterior chamber (less than 1 week) was also similar in the two groups.
Sodium hyaluronate-assisted trabeculectomy decreased the incidence of early postoperative complications like anterior chamber shallowing, choroidal detachment and hypotony, but it did not have any effect on hyphema or its clearance.
Clinical and Experimental Ophthalmology 07/2006; 34(5):421-4. · 1.96 Impact Factor
[show abstract][hide abstract] ABSTRACT: To introduce a new technique which aids to remove the pterygium head and facilitates the establishment of a smooth and clear corneal surface without extra scraping or polishing.
We used 12 eyes of 12 patients undergoing pterygium excision. Air was injected into the side of the cap of the pterygium head with a 30-gauge needle, to create a dissection plane between the pterygium head and the cornea. After blunt dissection and excision of the pterygium, the conjunctival autograft technique was applied. Complications, postoperative smoothness and clarity of the cornea, and the recurrence rates were evaluated.
Dissection with air was successfully performed in 9 eyes (75%) in which blunt dissection was carried out easily. The corneas were clear and smooth postoperatively. In 3 eyes (25%) dissection with air was not completely successful, and scraping with a crescent blade had to be performed. One of the eyes with incomplete air dissection could not be clearly scraped. No major complications were observed. The recurrence rate was 8.3% (1 eye).
This new technique is a safe, easy and cheap method for removing the pterygium head from the corneal surface, which also facilitates the establishment of a clear and smooth corneal surface.
[show abstract][hide abstract] ABSTRACT: We investigated the results of phacoemulsification surgery with or without capsular tension ring in eyes with traumatic subluxated cataracts with zonular dialysis. Capsular tension ring implantation before nucleus emulsification in subluxated cataracts will reduce various complications.
Annals of Ophthalmology 40(3-4):147-51. · 0.16 Impact Factor