M Krivokuca

Martin Luther University of Halle-Wittenberg, Halle, Saxony-Anhalt, Germany

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Publications (5)17.45 Total impact

  • M. Krivokuca, K. Werdan
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    ABSTRACT: Die vorliegende Übersicht über die Notfalltherapie der akuten Links- und Rechtsherzinsuffizienz sowie des kardiogenen Lungenödems und Schocks macht klar, wie viele wichtige ärztliche und organisatorische Aspekte in dieser Notfallsituation zu beachten sind. All dies muß ständig vorgehalten werden: spezialisiertes, hochmotiviertes ärztliches und Hilfspersonal, ein beachtliches medikamentöses Arsenal, zahlreiche Geräte zu supportiven Zwecken, ein großer diagnostischer Apparat und schließlich die Möglichkeit zu interventionellen koronaren Maßnahmen. Die im Text dieser Arbeit erklärten und diskutierten Empfehlungen zur Behandlung der akuten Herzinsuffienz sind in tabellarisch einprägsamer Form dargestellt, worauf besonders hingewiesen sei. Überblickt man die Entwicklung der kardiologischen Notfalltherapie in der letzten Dekade, besonders die überzeugenden Resultate von Notfall-PTCA’s drängen sich natürlich Fragen mit weit reichenden ökonomischen Konsequenzen auf: (1.) Wohin sollen die erstbehandelnden Ärzte ihre kardiologischen Notfälle schicken bzw. begleiten, in die nächste Klinik (wie man so leicht sagt, immer die beste) oder nicht doch lieber gleich in eine (meist wesentlich weiter entfernte) Spezialabteilung mit interventionellen Möglichkeiten? (2.) Wie steht es mit der flächendeckenden Versorgung kardiologischer Notfälle hierzulande?
    Der Internist 04/2012; 41(2):127-136. · 0.33 Impact Factor
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    ABSTRACT: Cerebral ischaemia caused by thromboembolism is a possible complication of diagnostic and interventional cardiac catheterization. In this case report we describe the diagnostic steps and successful treatment strategy in the management of a patient who suffered from cerebral ischaemia during cardiac catheterization. Initial CT scanning to exclude cerebral haemorrhage was followed by angiography through the cardiac catheterization sheath in the right femoral artery. Occlusion just before the intracranial bifurcation of the right internal carotid artery was found and local thrombolysis given with a reduced dose of 34 mg rt-PA. The subsequent angiogram showed restored perfusion in the affected vessel after completion of thrombolytic therapy and resolution of neurological symptoms.
    Zeitschrift für Kardiologie 08/2005; 94(7):474-8. · 0.97 Impact Factor
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    ABSTRACT: Paradoxical embolism via a patent foramen ovale (PFO) has been identified as a potential risk factor for ischaemic stroke. Such occurrences are associated with risk factors for deep vein thrombosis (DVT), e. g. pregnancy, immobilisation, and surgery of the lower limbs. A 54-year-old otherwise healthy female presented with acute onset motoric aphasia and brachiofacial right hemiparesis. The cranial computed tomography showed a left striatal ischaemic infarction. The patient's history revealed a variceal sclerotherapy with polydocanol 0,5% three days prior to the onset of symptoms. Echovist TCM doppler revealed a right-to-left shunt. A patent foramen ovale (PFO) was detected by transesophageal echocardiography. There was no evidence of DVT in bilateral lower-extremity venous duplex ultrasound scanning. Other potential risk factors of stroke including thrombophilia could not be identified. The patient was treated with a high dose regimen of heparin and a further anticoagulation treatment was recommended. This case suggests a probable causal relationship between variceal sclerotherapy and paradoxical embolism resulting in a stroke. Variceal sclerotherapy might be a potential, but rare risk of embolism.
    European journal of medical research 06/2004; 9(5):282-4. · 1.10 Impact Factor
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    ABSTRACT: We undertook this study to evaluate potential changes in cerebral vasoreactivity in patients with cardiac failure and their consequent dependence upon cardiac functional variables. A total of 50 patients with various degrees of heart failure, 20 age-matched controls and 20 normal controls were examined. Cerebrovascular reactivity was examined with the carbon dioxide technique. Mean flow velocities of both middle cerebral arteries as well as end-tidal carbon dioxide partial pressure were continuously registered. Normal controls were examined on two different occasions, to evaluate the technique's reproducibility. Cerebrovascular reactivity was significantly reduced in all examined patients as compared to controls, and in NYHA IV as compared to NYHA II and III patients. A significant relationship between cerebrovascular reactivity and left ventricular ejection fraction was evident. Reproducibility of the technique was satisfactory. Our study provided evidence of significantly reduced cerebrovascular reactivity in patients with cardiac failure, which was significantly related to the NYHA grade and the left ventricular ejection fraction.
    European Heart Journal 04/2000; 21(5):407-13. · 14.72 Impact Factor
  • M Krivokuca, K Werdan
    Der Internist 03/2000; 41(2 Pt 1):127-36. · 0.33 Impact Factor

Publication Stats

122 Citations
17.45 Total Impact Points

Institutions

  • 2000–2012
    • Martin Luther University of Halle-Wittenberg
      • Poliklinik für Innere Medizin III (Kardiologie, Angiologie)
      Halle, Saxony-Anhalt, Germany
    • Azienda Ospedaliera Santa Maria Nuova di Reggio Emilia
      Reggio nell'Emilia, Emilia-Romagna, Italy