M H Guillet

Université de Poitiers, Poitiers, Poitou-Charentes, France

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Publications (61)55.74 Total impact

  • Marie Hélène Guillet · Ewa Wierzbicka · Stephanie Guillet · Guy Dagregorio · Gerard Guillet ·
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    ABSTRACT: To assess the relative frequency of the different causes of pompholyx evoked in the literature. Prospective survey. Clinical outpatient setting. A total of 120 consecutive patients with pompholyx referred to our department from 2000 through 2003. Systematic investigation of different causes of pompholyx: fungal intertrigo, hyperhidrosis, atopy, contact eczema, and internal reactions with systematic provocation tests to metals, balsam of Peru, and food allergen when suspected. The present study found the following causes of pompholyx in the 120 patients: mycosis (10.0%); allergic contact pompholyx (67.5%), with cosmetic and hygiene products as the main factor (31.7%), followed by metals (16.7%); and internal reactivation from drug, food, or haptenic (nickel) origin (6.7%). The remaining 15.0% of patients were classified as idiopathic patients, but all were atopic. (Percentages do not total 100 because of rounding.) Our data confirm the existence of reactional pompholyx to interdigital-plantar intertrigos and endogenous reactions to metals or other allergens, but they mainly point at the unexpected importance of a so-called contact pompholyx in which cosmetic and hygiene products play a preponderant role compared with metals. The great frequency of atopic conditions, even if idiopathic pompholyx is not inferred as an equivalent of atopy, should lead to further causative investigations before undertaking more expensive or extensive treatments of refractory pompholyx.
    Archives of dermatology 01/2008; 143(12):1504-8. DOI:10.1001/archderm.143.12.1504 · 4.79 Impact Factor
  • G Guillet · M H Guillet · G Dagregorio ·
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    ABSTRACT: The aims of the study were to assess whether contact dermatitis in children could be due to a delayed hypersensitivity reaction to natural rubber latex (NRL) and to define risk factors for later occurrence of Type I hypersensitivity to this allergen. Among 1800 children investigated for contact dermatitis, 55 were referred on suspicion of rubber allergy and had patch tests to NRL, as well as prick tests and blood tests for specific immunoglobulin E (IgE). A 2-year follow-up was then carried out. Delayed hypersensitivity to NRL was confirmed in 32 children. Patch testing with NRL proved to be positive, and clinical improvement confirmed the diagnosis and relevance of patch tests. 30 of these 32 patients had associated atopic dermatitis (AD). Prick tests and blood tests for specific IgE to latex were negative at the time of diagnosis. A 2-year follow-up showed that 10 of 27 patients presenting initially with a positive patch test without associated Type I sensitization later developed immediate hypersensitivity. Children with AD are at high risk for allergy to NRL protein. Exclusion of this allergen should be strongly advised in atopics because of the dual risk of dermatitis and later evolution into severe Type I hypersensitivity.
    Contact Dermatitis 08/2005; 53(1):46-51. DOI:10.1111/j.0105-1873.2005.00634.x · 3.75 Impact Factor
  • G. Guillet · A. Labouche · M.-H. Guillet ·

    Annales de Dermatologie et de Vénéréologie 02/2005; 132(2):192-193. DOI:10.1016/S0151-9638(05)79240-1 · 0.92 Impact Factor
  • G. Guillet · G. Dagregorio · M.-H. Guillet ·
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    ABSTRACT: Background Contact sensitivity deserves to be assessed in acute vulvitis as well as chronic vulvar dermatitis with a specific orientation toward semen allergy whenever the pathology is post-coital.ObservationsThree observations of semen allergy are reported. Two women presented with post-coïtal vulvitis due to delayed hypersensitivity to semen proteins without associated specific IgE. The type 2 allergy was confirmed by positive patch-tests and disappearance of symptoms when using condoms. Another woman presented with oedematous vulvitis associated with asthma and malaise per and post-sexual intercourse. Positive prick-tests with husband's semen and blood tests for specific IgE led to the diagnosis of type 1 hypersensitivity to semen, with disappearance of both vulvar and systemic symptoms with the use of condoms.DiscussionImmediate or delayed type hypersensitivity may be discovered using prick and patch tests respectively. The observation of vulvitis or vulvar discomfort should promt such investigations, whenever a post-coital chronology is suggested. The good clinical pertinence of positive skin tests must be emphasized. Although type I hypersensitivity to semen is documented in the literature, with easy detection of specific IgE, delayed type 2 allergy presents as an as yet under-diagnosed etiology of post-coïtal vulvitis. Patch tests may help to confirm that contact dermatitis may be due to seminal proteins.
    Annales de Dermatologie et de Vénéréologie 02/2005; 132(2):123-125. DOI:10.1016/S0151-9638(05)79221-8 · 0.92 Impact Factor
  • G Guillet · L Robcis · C Herisse · M Sarrasin · M Delrez · M H Guillet ·

    Revue de l'infirmière 01/2005;
  • M. H. Guillet · L. Robcis · C. Hérissé · M. Delrez · J. P Rat · M. Sarrazin · C. Gaucher · G. Guillet ·

    Revue Française d Allergologie et d Immunologie Clinique 10/2004; 44(6):559-560. DOI:10.1016/j.allerg.2004.07.022 · 0.24 Impact Factor
  • G. Guillet · L. Robcis · C. Herisse · M. Sarrasin · M. Delrez · M. H. Guillet ·

    Revue Française d Allergologie et d Immunologie Clinique 10/2004; 44(6):563-566. DOI:10.1016/j.allerg.2004.07.019 · 0.24 Impact Factor
  • M. H. Guillet · G. Guillet ·

    Revue Française d Allergologie et d Immunologie Clinique 10/2004; 44(6):561-562. DOI:10.1016/j.allerg.2004.07.020 · 0.24 Impact Factor
  • M.-H. Guillet · G. Guillet ·
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    ABSTRACT: Background Although natural rubber latex hypersensitivity is considered as a major problem in adult, it may be still misdiagnosed in childhood. Patients and method We collected 27 observations of natural rubber latex contact urticaria in children under 15 years of age, 21 of them aged under 8. Results All of them where atopic and 19 out of 27 presented with other association paroxystic signs of immediate hypersensitivity, that were lately related to latex allergy (i. e. asthma, rhinitis, conjunctivitis, fainting). Cross-allergy to food allergens was present in 33 p. 100. Average level of specific IgE to natural rubber latex was 21.7 kU/l. One to 4 years follow up confirmed the benefit of latex eviction on urticaria as well as on associated symptoms. It led to the early detection of ficus allergy in 4 of them. Discussion This series confirms that atopy is at high risk for natural rubber latex allergy in children. These data suggest that atopic children are exposed too early to latex devices such as pacifiers, toodles of latex toys. Contact urticaria in children must be considered as a possible marker of other respiratory or general symptoms that may have been misconsidered under other etiologies.
    Annales de Dermatologie et de Vénéréologie 01/2004; 131(1):35–37. DOI:10.1016/S0151-9638(04)93539-9 · 0.92 Impact Factor
  • M Guillet ·

    Revue Française d Allergologie et d Immunologie Clinique 12/2003; 43(8):520-523. DOI:10.1016/S0335-7457(03)00264-8 · 0.24 Impact Factor
  • M. H Guillet · C Kauffmann-Lacroix · F Dromer · C Larsen · G Guillet ·
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    ABSTRACT: We report the observation of a patient who developed three episodes of urticaria and anaphylactic shock due to food allergy to “Penicillium italicum” a contaminant mold of skin of sausage and cheese. This patient previously had asthma that suggested an allergy to a brand of cheese. Skin tests were found positive to skin of sausage, flesh of sausage, cheese and Penicillium. All these products were contaminated with P. italicum and blood tests were found positive for IgE anti-penicillium. Cutaneous prick tests and anamnesis confirmed that the allergy only concerned mold of sausage and “tomme de Savoie” without allergy to other cheeses (such as camembert) or to penicillin. Patient was informed of a high risk of contact contamination in other foods. Since the responsibility of Penicillium is likely to be misdiagnosed, we think this mold should be tested anytime sausages and cheese are suspected.
    Revue Française d Allergologie et d Immunologie Clinique 12/2003; 43(8):520-523. DOI:10.1016/j.allerg.2003.09.004 · 0.24 Impact Factor
  • Guillet M.H · Kauffmann- Lacroix C · Dromer F · Larsen C · Guillet G ·

    Revue Française d Allergologie et d Immunologie Clinique 11/2003; 43(8):520-523. · 0.24 Impact Factor
  • G Guillet · M.-H Guillet ·
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    ABSTRACT: The diagnosis of atopic dermatitis (AD) includes reference to an allergic background and takes into account major and minor clinical criteria; among the latter are nonspecific flare factors. These nonspecific flare factors, including itching threshold, cutaneous reactivity to heat or cold, to sweating, to irritants, to contact with water, and psychological stress, may be predominant in patients with mild or moderate DA and deserve to be assessed in all AD patients prior to an allergic work-up. The involvement of extrinsic allergic or infectious factors is supported by many, although sometimes controversial, studies, some of which suggest a role for the pro-inflammatory effect of Staphyloccus aureus and others a role for airborne and food allergens.
    Revue Française d Allergologie et d Immunologie Clinique 12/2002; 42(8-42):793-797. DOI:10.1016/S0335-7457(02)00226-5 · 0.24 Impact Factor
  • M. H. Guillet · Y. Le Ru · G. Guillet · Morvan Chu ·

    Revue Française d Allergologie et d Immunologie Clinique 01/2001; 41(1):125-125. DOI:10.1016/S0335-7457(01)80053-8 · 0.24 Impact Factor
  • MH Guillet · G Guillet ·

    Revue Française d Allergologie et d Immunologie Clinique 01/2001; 41(1):126-126. DOI:10.1016/S0335-7457(01)80054-X · 0.24 Impact Factor
  • G. Guillet · M. H. Guillet ·

    Fuel and Energy Abstracts 01/2001; 41(1):126-126. DOI:10.1016/S0335-7457(01)80057-5
  • G Guillet · A Labouche · MH Guillet ·

    Fuel and Energy Abstracts 01/2001; 41(1):126-126. DOI:10.1016/S0335-7457(01)80056-3
  • MH Guillet · JP Codet · G Guillet ·

    Fuel and Energy Abstracts 01/2001; 41(1):126-126. DOI:10.1016/S0335-7457(01)80055-1
  • G Guillet · M H Guillet ·
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    ABSTRACT: A five month old child with atopic dermatitis developed contact dermatitis to almond with positive patch test, positive prick test, and class 4 anti-almond IgE. Focal lesions of persistent eczema were correlated with application of almond oil for 2 month on cheeks and buttocks. The child had not ingested almond and her mother did not report almond intake during her breast-feeding. This observation points to the problems of possible percutaneous sensitisation to food proteins. The study of skin ointments containing components of food origin in 27 food sensitized atopic patients confirm that the choice of an ointment for lesional skin is of importance.
    Allergie et immunologie 11/2000; 32(8):309-11.
  • M H Guillet · G Guillet ·
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    ABSTRACT: Allergic management of AD may be worthwhile since allergy may trigger the disease. A systematic evaluation of sensitizations overtime and study of their clinical involvement in 500 children with AD was carried out, including minor, moderate, and severe patients (defined by clinical scores). Standardized methods assessed the possibility of contact dermatitis as well as IgE dependant allergies. Contact dermatitis concerned fragrances and nickel. Contact dermatitis was observed in minor and moderate AD with a progressive increase: 11% of children under 2 years and 58% in those over 15 years of age. Later in older children, sensitization to cosmetics and occupational allergens occurred in close connection with the specific environment. As for IgE sensitization, investigation should be electived advised in moderate and severe AD. Inhalant allergen sensitization was observed in 66% in moderate AD and 93% in severe AD in the group of 7 or 15 years. Clinical confrontation was a better indicator of cutaneous involvement than atopen patch-test. It mainly concerned respiratory symptoms. In severe AD, food allergy was constantly observed and presented as a marker for severe atopic dermatitis. The main trophallergen differ according to the age and cultural habits: in children under 2 years of age, eggs, peanuts, milk, fish were the main offending agents. Later, main trophallergens were wheat flour, shellfish. Although spontaneous decrease of food allergy is sometimes observed, it must be pointed out that food allergy may still persist as a triggering factor in teenagers as well as in adult-hood. The allergologic diagnosis of atopic dermatitis should not focus on IgE dependent sensitization without patch testing.
    Allergie et immunologie 11/2000; 32(8):305-8.

Publication Stats

373 Citations
55.74 Total Impact Points


  • 2008
    • Université de Poitiers
      Poitiers, Poitou-Charentes, France
  • 2004-2005
    • Centre Hospitalier Universitaire de Poitiers
      Poitiers, Poitou-Charentes, France
  • 1996
    • CHRU de Strasbourg
      Strasburg, Alsace, France
  • 1991-1996
    • Centre Hospitalier Universitaire de Brest
      Brest, Brittany, France