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Publications (2)0 Total impact

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    ABSTRACT: Positive-pressure and initial-flow-rate (Hémorhéomètre) methods for the study of erythrocyte filtration through 5 micron diameter pores are highly sensitive to the presence of contaminating leucocytes in the erythrocyte test suspension. A pre-filtration step, in which heparinised or EDTA-anticoagulated whole-blood was passed through a column of Imugard IG500 cotton wool, was therefore developed. This procedure removed contaminating platelets and leucocytes, but not erythrocyte sub-populations, and is likely to improve the sensitivity and specificity of erythrocyte filtration techniques.
    Biorheology. Supplement: the official journal of the International Society of Biorheology 02/1984; 1:283-5.
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    ABSTRACT: Positive-pressure and initial-flow-rate (Hémorhéomètre) filtration systems were used to study the deformability of erythrocytes from whole blood stored in EDTA or heparin. When all contaminating platelets and leucocytes were removed from the erythrocyte suspension there was no significant anticoagulant effect on erythrocyte filtration. Blood may therefore be stored in K2EDTA (1.5 mg/ml blood) or lithium heparin (15 IU/ml blood) for up to 6 hours at room temperature prior to measurement of erythrocyte filterability.
    Biorheology. Supplement: the official journal of the International Society of Biorheology 02/1984; 1:279-81.