[Show abstract][Hide abstract] ABSTRACT: Rheumatoid arthritis is a chronic inflammatory autoimmune disease whose etiology is still unknown. Extra-articular manifestations are not uncommon. F-18 fluoro-2-deoxyglucose (F-18 FDG) positron emission tomography combined with computed tomography (PET/CT) is a useful tool to assess neoplastic diseases. However, some inflammatory conditions may also show high F-18 FDG uptake. We report a symptomatic rheumatoid arthritis patient showing marked F-18 FDG uptake in subcutaneous nodules, and cervical, supraclavicular, axillary, and pelvic lymph nodes. Detection of extra-articular inflammatory sites may improve our knowledge about inflammatory disorders of unknown etiology, and will certainly improve their management in the future. F-18 FDG PET/CT false-positives results for malignancy may be avoided in patients with rheumatoid arthritis.
Clinical nuclear medicine 07/2010; 35(7):540-1. DOI:10.1097/RLU.0b013e3181e05eb9 · 3.93 Impact Factor