Kazumichi Tsukamoto

Tottori University, Tottori, Tottori-ken, Japan

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Publications (2)4.08 Total impact

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    ABSTRACT: The clinical differentiation of Parkinson's disease (PD) from multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) may be challenging, especially in their early stages. The aim of this study was to evaluate the utility of apparent diffusion coefficient (ADC) measurement to distinguish among these degenerative disorders. Twenty-five MSA, 20 PSP, and 17 PD patients and 18 healthy controls were retrospectively studied. Axial diffusion-weighted and T2-weighted images were obtained using a 3-T MR system. Regions of interest (ROIs) were precisely placed in the midbrain, pons, putamen, globus pallidus, caudate nucleus, thalamus, superior cerebellar peduncle, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus, and the regional ADC (rADC) value was calculated in each ROI. In MSA, rADC values in the pons, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus were significantly higher than in PSP, PD, and controls. Furthermore, rADC values in the posterior putamen were significantly higher in MSA than in PSP and controls. In PSP, rADC values were significantly higher in the globus pallidus and midbrain than in MSA, PD, and controls. Furthermore, rADC values in the caudate nucleus and superior cerebellar peduncle were significantly higher in PSP than in MSA and controls. In PD, there were no significant differences in the rADC values compared to in MSA, PSP, and controls in all regions. Evaluation of rADC values in characteristic lesions in MSA, PSP, and PD by placing ROIs using 3-T systems can provide useful additional information for differentiating these disorders.
    Neuroradiology 01/2012; 54(9):947-55. · 2.70 Impact Factor
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    ABSTRACT: We demonstrated 2 cases of uterine endometrial stromal sarcoma with emphasis on diffusion-weighted imaging. The tumors showed high signal intensity, and their tumor venous thrombi were clearly depicted on diffusion-weighted imaging. Diffusion-weighted imaging is a useful method not only for diagnosis of endometrial stromal sarcoma but also for preoperative planning.
    Journal of computer assisted tomography 01/2010; 34(3):377-9. · 1.38 Impact Factor