Donald J. Maclean

Publications (2)31.2 Total impact

• Source

  Available from: Sucheta Tripathy

  Article: Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis.

  Brett M Tyler, Sucheta Tripathy, Xuemin Zhang, Paramvir Dehal, Rays H Y Jiang, Andrea Aerts, Felipe D Arredondo, Laura Baxter, Douda Bensasson, Jim L Beynon, [......], Brian M Smith, Bruno W S Sobral, Astrid Terry, Trudy A Torto-Alalibo, Joe Win, Zhanyou Xu, Hongbin Zhang, Igor V Grigoriev, Daniel S Rokhsar, Jeffrey L Boore
  [show abstract] [hide abstract]
  ABSTRACT: Draft genome sequences have been determined for the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum. Oömycetes such as these Phytophthora species share the kingdom Stramenopila with photosynthetic algae such as diatoms, and the presence of many Phytophthora genes of probable phototroph origin supports a photosynthetic ancestry for the stramenopiles. Comparison of the two species' genomes reveals a rapid expansion and diversification of many protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily of 700 proteins with similarity to known oömycete avirulence genes.
  Science 10/2006; 313(5791):1261-6. · 31.20 Impact Factor
• Source

  Available from: Brett Tyler

  Article: Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis

  Brett M Tyler, Sucheta Tripathy, Xuemin Zhang, Donald J. Maclean, et al
  [show abstract] [hide abstract]
  ABSTRACT: Draft genome sequences have been determined for the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum. Oomycetes such as these Phytophthora species share the kingdom Stramenopila with photosynthetic algae such as diatoms, and the presence of many Phytophthora genes of probable phototroph origin supports a photosynthetic ancestry for the stramenopiles. Comparison of the two species' genomes reveals a rapid expansion and diversification of many protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily of 700 proteins with similarity to known oomycete avirulence genes.