F Nome

Publications (5)34.27 Total impact

• Article: Effects of surfactants on cobalamin dependent methyl transfer. Influence of aqueous and reversed micelles on the interaction of mercuric ion with methylcobalamin.

  G C Robinson, F Nome, J H Fendler
  Journal of the American Chemical Society 08/1977; 99(15):4969-76. · 9.91 Impact Factor
• Article: Novel prebiotic systems: nucleotide oligomerization in surfactant entrapped water pools.

  D W Armstrong, F Nome, J H Fendler, J Nagyvary
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  ABSTRACT: Oligomerization of 5' -TMP in water pools entrapped by dodecyl-ammonium chloride surfactant aggregates in benzene: hexane in the presence of dicyanodiimide at temperatures ranging from 21 degree -72 degree resulted in the formation of linear and cyclic oligonucleotides containing up to pentamers. Effects of temperature, time and surfactants have been examined. Rate constants for the formation of oligomers have been determined at five different temperatures. These data afforded values of (formula: see text). Prebiotic significance of these results are discussed.
  Journal of Molecular Evolution 06/1977; 9(3):213-23. · 2.27 Impact Factor
• Article: Effects of surfactants on the interaction of vitamin B12a with cysteine and N-alkanoylcysteines in water and in benzene. Influence of aqueous micelles and solvent restrictions.

  F Nome, J H Fendler
  Journal of the American Chemical Society 04/1977; 99(5):1557-69. · 9.91 Impact Factor
• Article: Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.

  J H Fendler, F Nome, J Nagyvary
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  ABSTRACT: Cationic amino acids, arginine and lysine partition differentially from water into aqueous micellar sodium dodecanoate. Conversely, partitioning of serine, glycine, aspartic acid, glutamic acid, threonine, alanine, proline, valine, leucine, phenylalanine and isoleucine do not vary appreciably. Partitioning from neat hexane into dodecylammonium propionate trapped water in hexane is, however, dependent upon both electrostatic and hydrophobic interactions. These results imply that the interior of dedecylammonium propionate aggregates is negatively charged and is capable of hydrogen bonding in addition to providing a hydrophobic enviroment. The solubilities of amino acids in neat hexane substantiate the previously derived amino acid hydrophobicity scale. Relevance of partitioning in these systems to the postulated selective amino acid compartmentalization is discussed.
  Journal of Molecular Evolution 12/1975; 6(3):215-32. · 2.27 Impact Factor
• Article: Effects of surfactants on ligand exchange reactions in vitamin B12a in water and in benzene. Influence of aqueous micelles and of solvent restrictions.

  J H Fendler, F Nome, H C Van Woert
  Journal of the American Chemical Society 11/1974; 96(21):6745-53. · 9.91 Impact Factor