J B Soriano

Publications (4)11.27 Total impact

• Article: [Comorbidities in patients hospitalized due to chronic obstructive pulmonary disease. A comparative analysis of the ECCO and ESMI studies].

  P Almagro, F López, F J Cabrera, J Portillo, M Fernández-Ruiz, E Zubillaga, J Díez, P Román, J Murcia-Zaragoza, R Boixeda, C Murio, J B Soriano
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  ABSTRACT: The presence of associated diseases is very frequent in patients hospitalized due to exacerbation of COPD. We have studied the comorbidities of patients admitted due to the disease in the Spanish Internal Medicine Services and we have evaluated the variations in regards to a previous study (ECCO study) performed two years earlier. A cross-sectional, multicenter and cohort study was performed. Patients hospitalized due to exacerbation of COPD in Spanish Internal Medicine Services were enrolled. All the patients were studied for the presence of comorbidity using the Charlson index and a questionnaire with relevant conditions not included in this index. Furthermore, spirometric data were collected on the duration of the disease or home treatment, among other variables. A total of 1004 patients (398 in the ECCO study and 606 in the ESMI study) were studied. Of these, 89.4% were males, with mean age of 73 years (SD: 9.5 years). The patients of the ESMI study obtain higher scores on the Charlson index (3.04 vs. 2.71; P<0.01), and had a greater prevalence of ischemic heart disease (17 vs. 22.0%; P<0.05), heart failure (26.9 vs. 35.5%; P<.002), peripheral vascular disease (12.6 vs. 17.4%; P<.02), arterial hypertension (54.8 vs. 65.6%; P<.001), diabetes mellitus (29.4 vs. 37%; P<.02) and renal failure (6.5 vs. 16.8%; P<.0001). This study confirms the elevated prevalence of associated diseases in patients with COPD who are admitted to the Spanish Internal Medicine Services and the increase of comorbidities.
  Revista Clínica Española 04/2012; 212(6):281-6. · 2.01 Impact Factor
• Article: Comorbidities and short-term prognosis in patients hospitalized for acute exacerbation of COPD. The ESMI study.

  P Almagro, F J Cabrera, J Diez, R Boixeda, B Ortiz, C Murio, J B Soriano
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  ABSTRACT: Abstract: BACKGROUND:Comorbidities are frequent in patients hospitalized for COPD exacerbation, but little is known about their relation with short-term mortality and hospital readmissions. Our hypothesis is that the frequency and type of comorbidities impair the prognosis within 12 weeks after discharge. MATERIAL AND METHODS:A longitudinal, observational, multicenter study of patients hospitalized for a COPD exacerbation with spirometric confirmation was performed. Comorbidity information was collected using the Charlson index and a questionnaire that included other common conditions not included in this index. Dyspnea, functional status, and previous hospitalization for COPD or other reasons among other variables were investigated. Information on mortality and readmissions for COPD or other causes was collected up to 3 months after discharge. RESULTS:We studied 606 patients, 594 men (89.9%), with a mean (SD) age of 72.6 (9.9) years and a post-bronchodilator FEV1 of 43.2 % (21.2). The mean Charlson index score was 3.1 (2.0). On admission, 63.4% of patients had arterial hypertension, 35.8% diabetes mellitus, 32.8% chronic heart failure, 20.8% ischemic heart disease, 19.3% anemia and 34% dislipemia. Twenty-seven patients (4.5%) died within 3 months. The Charlson index was an independent predictor of mortality (p<0.003; O.R.1.23; C.I. 95%: 1.07-1.40), even after adjustment for age, FEV1 and functional status measured with the Katz index. Comorbidity was also related with the need for hospitalization from the emergency room, length of stay, and hospital readmissions for COPD or other causes. CONCLUSIONS:Comorbidities are common in patients hospitalized for a COPD exacerbation, and they are related with short-term prognosis.
  Chest 04/2012; · 5.25 Impact Factor
• Article: [Risk of osteoporotic fracture and hip fracture in patients with chronic obstructive pulmonary disease].

  J Díez-Manglano, F López-García, J Barquero-Romero, N Galofré-Alvaro, L Montero-Rivas, P Almagro-Mena, J B Soriano
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  ABSTRACT: Osteoporosis is a frequent comorbidity in patients with chronic obstructive pulmonary disease (COPD). We have studied the risk of major osteoporotic fracture and hip fracture in patients with COPD. A multicenter cross-sectional study was performed in Spain in 26 hospitals of 16 regional communities. Patients diagnosed with COPD who required admission to the Internal Medicine Service due to exacerbation of their respiratory disease were enrolled. COPD was confirmed by post-bronchodilator spirometry in stable state: maximum expiratory volume in the first second (FEV₁) < 80% of the theoretical value and quotient FEV(1)/FVC < 0.70 and percent predicted after the administration of a bronchodilator. Dyspnea was evaluated with the modified Medical Research Council (mMRC) dyspnea scale. The principal variable was the likelihood of fracture evaluated with the FRAX® tool for the Spanish population. Three hundred and ninety two patients, 347 (88%) men, with a mean (SD) age of 73.7 (8.9) years and a mean FEV₁ of 1.23 liters (43.3% of predicted) were enrolled. Only 37 patients (9.4%), 27 men and 10 women had been diagnosed previously of osteoporosis. Overall, 1.8% (95% CI: 0.9-3.6) had a 10-year probability of major osteoporotic fracture ≥ 20% and 49.7% (95% CI: 44.8-54.7) had a probability of hip fracture ≥ 3%. No relationship was observed between the probability of fracture and GOLD stage or mMRC dyspnea scale. The diagnosis of osteoporosis is uncommon in our COPD patients. However, half of them have a high probability of a hip fracture in the next 10 years.
  Revista Clínica Española 09/2011; 211(9):443-9. · 2.01 Impact Factor
• Article: Riesgo de fractura osteoporótica y de cadera en pacientes con enfermedad pulmonar obstructiva crónica

  J. Díez-Manglano, F. López-García, J. Barquero-Romero, N. Galofré-Alvaro, L. Montero-Rivas, P. Almagro-Mena, J. B. Soriano
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  ABSTRACT: AimOsteoporosis is a frequent comorbidity in patients with chronic obstructive pulmonary disease (COPD). We have studied the risk of major osteoporotic fracture and hip fracture in patients with COPD.
  Revista Clinica Espanola - REV CLIN ESPAN. 01/2011; 211(9):443-449.
• Article: [Study of the comorbidities in hospitalized patients due to decompensated chronic obstructive pulmonary disease attended in the Internal Medicine Services. ECCO Study].

  P Almagro, F López García, F J Cabrera, L Montero, D Morchón, J Díez, F de la Iglesia, F B Roca, M Fernández-Ruiz, J Castiella, E Zubillaga, J Recio, J B Soriano
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  ABSTRACT: Evaluate comorbidity in patients hospitalized due to COPD in the Internal Medicine services. An observational, prospective and multicenter study. The Charlson index and a specific questionnaire were used. A total of 398 patients, 353 men (89%), with mean age of 73.7 years (8.9) and mean FEV(1) of 43.2% (12.5), were included. The most frequent comorbidities were: arterial hypertension (55%), arrhythmias (27%) and diabetes mellitus (26%). A total of 27% suffered heart failure, 17% coronary disease and 9% previous myocardial infarction. The number of associated chronic diseases was 3.6 (1,8). Score on Charlson index was 2.72 (2). The patients hospitalized due to decompensated COPD had an elevated comorbidity.
  Revista Clínica Española 03/2010; 210(3):101-8. · 2.01 Impact Factor