ABSTRACT: A case report was carried out in two asthmatic patients treated with a new health natural product named Vimang®, an aqueous extract of Mangifera indica L stem bark, which has been registered as antioxidant and anti-inflammatory. A 39 years-old female with persistent moderated asthma and a 43 years-old male with persistent severe asthma were treated orally with Vimang® (capsule 300 mg, one every 8 h) during three months. Respiratory functional tests and determination of total serum immunoglobulin E (IgE), eosinophil cationic protein (ECP) and metalloproteinase-9 (MMP-9) activity were done at times 0, 6 and 12 weeks, respectively. An improvement in the volume of force expiration (FEV1) was observed for both patients. The values of IgE, ECP and the enzymatic activity of MMP-9 decreased also for both patients. These results could open the way to further clinical researches about the use of Vimang® as an alternative for the treatment of bronchial asthma.
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. 01/2009;