To investigate the effect of the integrated therapy of traditional Chinese and Western medicine in the treatment of BPH complicated by diabetes mellitus.
Fifty-two cases of BPH complicated by diabetes mellitus were equally randomized to a treatment group and a control group, and both underwent transurethral plasmakentic vaporization when fasting glucose was kept at 6.0 - 8.0 mmol/L, followed by anti-infection, rehydration and semeiologically supportive therapies. And both of the two groups received Chinese medicinal herbal treatment before and after surgery.
Neither of the two groups showed postoperative electrolyte disturbance, ketone acidosis, or hypoglycemia. The incidences of postoperative constipation, bladder convulsion and urinary tract infection were significantly lower in the treatment group than in the control group (P < 0.05).
The integrated therapy of traditional Chinese and Western medicine for BPH with diabetes mellitus can not only smoothly tide the patients over the perioperative period, but also improve their quality of life by reducing postoperative constipation, bladder convulsion and urinary tract infection.
Zhonghua nan ke xue = National journal of andrology 06/2011; 17(6):568-70.
To compare the safety and efficacy of the two surgical alternatives, transurethral bipolar vaporization resection of the prostate (TUBVP) and holmium laser enucleation of the prostate (HOLEP), in the treatment of large benign prostatic hyperplasia (BPH).
Retrospective analyses were made of 56 cases of large BPH ( >80 ml), 34 treated by TUBVP with the Bipolar Vaporization System (ACMI Medical Ltd, U.K.) at 160 W in cutting and 80 W in coagulation mode, and 22 by HOLEP with the Holmium Laser System (LUMNIS Ltd, US) at 100W. The safety and efficacy of the two approaches were assessed based on the operative and follow-up data.
Blood loss was significantly less in the HOLEP than in the TUBVP group ( P < 0.01), but the time of postoperative bladder irrigation and catheter indwelling was obviously shorter in the latter. IPSS, Qmax and Residual unine were markedly improved at 1 and 3 months after the surgery, with no statistically significant differences between the two groups.
Both TUBVP and HOLEP are safe and effective surgical options for the treatment of large BPH. Particularly the former, easier to be popularly applied, is promising to be a new "gold standard" in the surgical treatment of BPH.
Zhonghua nan ke xue = National journal of andrology 10/2008; 14(10):907-10.
To improve the level of clinical diagnosis and differential diagnosis of benign and malignant prostate lesions.
One hundred and nine cases of prostate cancer and prostate hyperplasia were evaluated by the expression of high molecular weight cytokeratin (CK34BE12), prostate specific antigen (PSA) and protein P53 gene using the immunohistochemical technique.
The basal-cells in all of the benign lesions were stained with the CK34BE12 and PSA, while it had not immunoreactivity with P53. In contrast, the prostate carcinoma were not stained or partly stained with the CK34BE12 and PSA, but P53 show significant immunoreactivity with the tissue.
Based on the routine histological studies with the expression of CK34BE12 and PSA together, they can indicate the existence of basal-cell distinctly and show indirectly whether the basal-cell is integrated. Combining the expression of P53 to determine the existence of cancer gene, it can help to distinguish benign and malignant prostate lesions.
Zhonghua nan ke xue = National journal of andrology 05/2006; 12(4):340-2.