Y Sampeur

Publications of Y Sampeur

• Long term tissue response to titanium coated with diamond like carbon.

  Authors: M Mohanty, T V Anilkumar, P V Mohanan, C V Muraleedharan, G S Bhuvaneshwar, F Derangere, Y Sampeur, R Suryanarayanan

  Biomolecular engineering. 09/2002; 19(2-6):125-8.

  Diamond like carbon (DLC) coatings were deposited on to Ti substrates by plasma enhanced chemical vapor deposition technique. Ti and DLC/Ti samples were implanted in skeletal muscle of rabbits. TheDiamond like carbon (DLC) coatings were deposited on to Ti substrates by plasma enhanced chemical vapor deposition technique. Ti and DLC/Ti samples were implanted in skeletal muscle of rabbits. The samples were explanted after 1, 3, 6 and 12 months and the tissue-cell interaction was studied. Our data indicate both DLC/Ti and bare Ti to be compatible with skeletal muscle.

• Quantitation of platelet adhesion to Ti and DLC-coated Ti in vitro using (125)I-labeled platelets.

  Authors: L K Krishnan, N Varghese, C V Muraleedharan, G S Bhuvaneshwar, F Derangère, Y Sampeur, R Suryanarayanan

  Biomolecular engineering. 09/2002; 19(2-6):251-3.

  Measurement of platelet adhesion in vitro is a good indicator of its reactivity to implant devices in vivo. Platelets were labeled with I-125 without affecting its normal morphology and function andMeasurement of platelet adhesion in vitro is a good indicator of its reactivity to implant devices in vivo. Platelets were labeled with I-125 without affecting its normal morphology and function and the labeled platelets were suspended in platelet poor plasma and exposed to Ti and diamond like carbon-coated (DLC) Ti discs, under dynamic conditions, using a parallel plate flow chamber. The test materials were washed, dried, exposed to a phosphor screen and scanned to get the images. The number of platelets that adhered to Ti was found to be higher than those that adhered to DLC coated Ti sample, irrespective of the shear stress which was varied between 2 and 16 dynes/cm(2).

• In vitro cytocompatibility studies of Diamond Like Carbon coatings on titanium.

  Authors: T V Kumari, P R Anil Kumar, C V Muraleedharan, G S Bhuvaneshwar, Y Sampeur, F Derangere, R Suryanarayanan

  Bio-medical materials and engineering. 02/2002; 12(4):329-38.

  Diamond like carbon (DLC) films were deposited on to titanium (Ti) substrates by Plasma Enhanced Chemical Vapour Deposition (PECVD) process. The quality of the films were checked by Raman spectra andDiamond like carbon (DLC) films were deposited on to titanium (Ti) substrates by Plasma Enhanced Chemical Vapour Deposition (PECVD) process. The quality of the films were checked by Raman spectra and nano-hardness tests. The cytocompatibility of titanium and DLC coated titanium were studied using continuous cell lines of mouse fibroblast cells ( L-929), Human Osteoblast cells (HOS) and primary human umbilical cord vein endothelial cells (HUVEC). The cellular responses to the materials were assessed both quantitatively and qualitatively. The adhesion and spreading of cells on materials were compared using Ti as a control. Present study indicates an improved cytocompatibility of DLC coated Ti in comparison to bare Ti.

• Evaluation of maximization sensitization of the saline extract of titanium coated with diamond like carbon material

  Authors: PV Mohanan, CV Muraleedharan, GS Bhuvaneshwar, F Derangere, Y Sampeur, R Suryanarayanan, others

  Toxicology International. 14(1):63.

• Quantitation of platelet adhesion to Ti and DLC-coated Ti in vitro using 125I-labeled platelets

  Authors: LK Krishnan, N Varghese, CV Muraleedharan, GS Bhuvaneshwar, F Derangere, Y Sampeur, R Suryanarayanan

  Biomolecular engineering. 19(2-6):251-253.

• Quantitation of platelet adhesion to Ti and DLC-coated Ti in vitro using 125I-labeled platelets

  Authors: L.K Krishnan, N Varghese, C.V Muraleedharan, G.S Bhuvaneshwar, F Derangère, Y Sampeur, R Suryanarayanan

  Biomolecular Engineering.

  Measurement of platelet adhesion in vitro is a good indicator of its reactivity to implant devices in vivo. Platelets were labeled with I-125 without affecting its normal morphology and function andMeasurement of platelet adhesion in vitro is a good indicator of its reactivity to implant devices in vivo. Platelets were labeled with I-125 without affecting its normal morphology and function and the labeled platelets were suspended in platelet poor plasma and exposed to Ti and diamond like carbon-coated (DLC) Ti discs, under dynamic conditions, using a parallel plate flow chamber. The test materials were washed, dried, exposed to a phosphor screen and scanned to get the images. The number of platelets that adhered to Ti was found to be higher than those that adhered to DLC coated Ti sample, irrespective of the shear stress which was varied between 2 and 16 dynes/cm2.