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ABSTRACT: An antitumour-promoting activity in two-stage carcinogenesis, is found in the methanol extract of the Carthami Flos (Carthamus tinctorius L.; Compositae), which is a traditional Chinese medicine and natural pigment of rouge additivies in certain Asian countries. From these active fractions, δ5- and δ7-sterol fractions were separated. The separation was examined for inhibitory activity against TPA-induced inflammatory ear oedema in mice. Stigmasterol (71% in the mixture) was the most abundant of 14 sterols identified in the δ5-sterol fraction. Schottenol (70% in the mixture) constituted the dominant sterol of the δ7-sterol fraction. Furthermore, stigmasterol markedly inhibited tumour promotion in two-stage carcinogenesis experiments.
Phytotherapy Research 01/2006; 8(6):327 - 331. · 2.09 Impact Factor
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04/2002;
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ABSTRACT: A novel triterpenoid isolated from the non-saponifiable lipid of the aerial part extract of white bryony (Bryonia dioica) was established to be 3beta-hydroxy-27-norcycloartan-24-one based on spectroscopic methods. Isolation and identification of other known cycloartane triterpenoids and sterols also are described.
Phytochemistry 12/1998; 49(6):1757-1760. · 3.35 Impact Factor
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ABSTRACT: Ten tabular- and eight ligulate-flowers and seven flower-heads from twenty-two species of Compositae were investigated for their alkanediol constituents. All of the flowers contained alkanediols in small amounts suggesting their widespread occurrence in these flowers. Twelve alkanediols were identified as syn(R,S and/or S,R)-C(21)-, C(23)-, C(25)-, and C(27)--C(35)-alkane-6,8-diols among which syn-hentriacontane-6,8-diol occurred abundantly in many of the flowers.
Phytochemistry 12/1998; 49(6):1637-1640. · 3.35 Impact Factor
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ABSTRACT: A C31, alkanediol isolated from the methanol extract of dried flower petals of Carthamus tinctorius was established to have the structure (6R,8S and/or 6S,SR)-erythro-hentriacontanc-6,8-diol by spectral and chemical methods. Eleven other erythro-alkane-6,8-diols with carbon numbers C21, C23, C25, C27–C30 and C32–C31 were also isolated and characterized. This is the first report of the natural occurrence of secondary erythro-alkane-β-diols.
Phytochemistry.
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ABSTRACT: A novel triterpenoid isolated from the non-saponifiable lipid of the aerial part extract of white bryony (Bryonia dioica) was established to be 3β-hydroxy-27-norcycloartan-24-one based on spectroscopic methods. Isolation and identification of other known cycloartane triterpenoids and sterols also are described.
Phytochemistry.
