Sungkyu Lim

Publications (3)9.01 Total impact

• Source

  Available from: snupharm.ac.kr

  Article: In-vivo measurements of the dielectric properties of breast carcinoma xenografted on nude mice.

  Jeiwon Cho, Jeonghoon Yoon, Sungjoon Cho, Kihyun Kwon, Sungkyu Lim, Daeduk Kim, Eun Sook Lee, Chul Hwan Kim, Jin Wook Choi, Changyul Cheon, Youngwoo Kwon
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  ABSTRACT: A developing method of cancer detection is to use electromagnetic waves to compare the dielectric properties of normal and cancerous tissue. Because most of the previous studies consisted of dielectric measurements taken ex-vivo, this study investigated the advantages of in-vivo measurements, obtained using the newly developed insertion-type planar probe, through the measurements of cancer (MDA MB 231), which was cultivated and implanted into the mammary fat pad of nude mice. Reflection coefficients were obtained in the broadband frequency range from 0.5 to 30 GHz, from which broadband complex permittivity data was extracted. Complex permittivity, in addition to other parameters such as conductivity and characteristic frequency, were used to make comparisons between cancerous tissue, normal muscle tissue and fat tissue, as well as comparisons between in-vivo and ex-vivo measurements. This study investigated the suitability of in-vivo cancer detection using microwaves with the newly developed insertion-type planar probe. Results showed that both sensitivity and specificity of the current method was 97%. In addition, predictive values were 99% for the positive and 94% for the negative, thus greatly enhancing the practicality of this method. In conclusion, it was demonstrated that in-vivo measurements are highly beneficial in studying the potential of microwaves as a diagnostic tool of breast cancer, especially in combination with the newly developed insertion-type planar probe.
  International Journal of Cancer 09/2006; 119(3):593-8. · 5.44 Impact Factor
• Source

  Available from: lw23.com

  Article: Planar type probe with multiple-polarization response for in-vivo permittivity measurements of heterogeneous biological tissues

  Kihyun Kwon, Sungkyu Lim, Sungjoon Cho, Jeonghoon Yoon, Jeiwon Cho, Changyul Cheon, Youngwoo Kwon
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  ABSTRACT: A three-way planar-type probe optimized for in-vivo permittivity measurements of biological materials has been developed. The probe in this letter consists of three orthogonally-faced probing apertures, which allows one to make accurate and uninterrupted measurements in three different directions per each insertion. As a result, this probe is significantly less invasive for the collection of the desired information of the biological materials, thus providing a vastly improved solution for in-vivo measurements. This probe can also be used for microwave ablation, in which case the treating region can be significantly expanded
  IEEE Microwave and Wireless Components Letters 02/2006; · 1.72 Impact Factor
• Article: Novel low-cost planar probes with broadside apertures for nondestructive dielectric measurement of biological materials at microwave frequencies

  Byoungjoong Kang, Jae-Hyoung Park, Jeiwon Cho, Kihyun Kwon, Sungkyu Lim, Jeonghoon Yoon, Changyul Cheon, Yong-Kweon Kim, Youngwoo Kwon
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  ABSTRACT: Novel planar-type probes were developed to demonstrate the possibility of replacing the existing high-cost open-ended coaxial probes. The planar probes of this study define an aperture on the broadside of the probe body. In this way, the contact area can be maximized and/or customized according to specific medical needs. The probes with various aperture sizes and shapes can also be fabricated simultaneously in a single batch process. Three probes are developed in this paper: a probe combining two laminates, a microelectromechanical systems (MEMS)-based probe with a single benzocyclobutene (BCB) layer on a quartz substrate, and another MEMS probe with two BCB layers defined on a silicon substrate. The third probe was specifically designed for monolithic integration with driving circuits on a single substrate. Limitations in the high-frequency performance of the planar probes were carefully studied, and higher order modes and incomplete shielding were found to be the main causes. The measurement results of each probe showed excellent compatibility with those of the open-ended coaxial probe up to almost 40 GHz. The proposed planar-type probes have great potentials for practical medical applications in view of low cost, disposability, and monolithic integration capability with the driving circuits.
  IEEE Transactions on Microwave Theory and Techniques 02/2005; · 1.85 Impact Factor