S. Arora

Guru Nanak Dev University, Amritsar, State of Punjab, India

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Publications (19)16.28 Total impact

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    ABSTRACT: In the present study, two chloroform extracts of fruits of Terminalia chebula viz. "CHL1" and "CHL 2" prepared by maceration and sequential method respectively was compared for their antioxidant efficacy and phenolic content. The extraction procedure of plant material plays an important role in the activity of phytochemicals. Also, the assessment of antioxidant capacity of phytochemicals cannot be executed precisely by any single method due to complex nature of phytochemicals as multiple reaction characteristics and mechanisms can be involved. So, no single assay could accurately reflect comparison in a mixed or complex system. Therefore in the present study the comparison of extracts was done by using most widely used assays viz. DPPH, deoxyribose, reducing power, chelating power and lipid peroxidation assay. Furthermore, the UV-Vis spectrum of both extracts and the correlation between total phenolic content was examined in order to give an orientation to the search of phytochemicals responsible for their activity. From the results, it was concluded that antioxidant activity and phenolic compounds were predominant in the 'CHL 2' prepared by sequential method. The present study enlightening the useful extraction procedure of plant material.
    Journal of basic and clinical pharmacy. 06/2011; 2(3):143-9.
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    [Show abstract] [Hide abstract]
    ABSTRACT: In the present study, two chloroform extracts of fruits of Terminalia chebula viz. "CHL1" and "CHL 2" prepared by maceration and sequential method respectively was compared for their antioxidant efficacy and phenolic content. The extraction procedure of plant material plays an important role in the activity of phytochemicals. Also, the assessment of antioxidant capacity of phytochemicals cannot be executed precisely by any single method due to complex nature of phytochemicals as multiple reaction characteristics and mechanisms can be involved. So, no single assay could accurately reflect comparison in a mixed or complex system. Therefore in the present study the comparison of extracts was done by using most widely used assays viz. DPPH, deoxyribose, reducing power, chelating power and lipid peroxidation assay. Furthermore, the UV-Vis spectrum of both extracts and the correlation between total phenolic content was examined in order to give an orientation to the search of phytochemicals responsible for their activity. From the results, it was concluded that antioxidant activity and phenolic compounds were predominant in the 'CHL 2' prepared by sequential method. The present study enlightening the useful extraction procedure of plant material.
    Journal of basic and clinical pharmacy. 03/2011; 2(2):115-24.
  • Reproductive biomedicine online 09/2008; 17:S-26–S-27. · 2.68 Impact Factor
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    ABSTRACT: the Sureview@ catheter to further refine our dmique of ET, The principle of successful ET being depositing the 'lbryos as gently as possible during IVF, avoiding maneuvers that might "gger uterinecontractions which could adversely affect the results of this t limiting step in human IVE On one hand is an hypothesis that an lIIIediate withdrawal could alter the position of the air-bubble alongwith rembryos due to a transient negative pressure created by the immediate Ihdrawl of the catheter towards the cervix and this could affect pregnancy rs.Onthe other hand, the time during which the embryo transfer catheter 'lllains in the cervical canal might be related to stimulation of contractions. r objective of the present study was to investigate the influence of the rinterval before withdrawal of the catheter after Transabdominal Sonog-'!by(TAS) guided embryo deposition and its influence on the ART Irome, DESIGN:This prospective, comparative study was performed in an amic private ART center. \IATERIALS AND METHODS: To eliminate the effect of variables, we donned this study on 80 consecutive donor egg recipients undergoing Tsfrom September 2005 till March 2006 by the same physician, The OO1en were prospectively randomized into two groups namely Group A or Control Group where we continued our regular practice of a slow :thdrawal of the ET catheter immediately after embryo deposit (n = 51); iGroupB or the Study Group where we paused and clocked a 20 second jaybefore we withdrew the Sureview@ catheter (n = 29), Both the groups Ire matchedas regards age, number and grade of embryos transferred as !IIasthe endometrial thickness & morphology, RESULTS: The pregnancy rates in both the groups were 50,98 (26/51) ~ 51.72%(15/29) respectively, with no significant differences. There Irenostatistically significant differences in pregnancy rates or implanta-I ratesbetween the two patient groups. CONCLUSION: The results suggest that the deposition -withdrawal .mal of 20 seconds does not contribute to increasing the success in a IIOr Egg IVF program, We can conclude that either the waiting interval 10seconds is not adequate to delineate differences between the two I .!Ips or that the retention time before withdrawing the catheter is not a ! 101 that influences pregnancy rate. However, much larger multicentric
    American Society OF REPRODUCTIVE mEDICINE, NEW ORLEANS,USA; 10/2006
  • Article: P-322
    Fertility and Sterility - FERT STERIL. 01/2006; 86(3).
  • Article: P-317
    Fertility and Sterility - FERT STERIL. 01/2006; 86(3).
  • Article: P-321
    Fertility and Sterility - FERT STERIL. 01/2006; 86(3).
  • Article: P-315
    Fertility and Sterility - FERT STERIL. 01/2006; 86(3).
  • Article: P-879
    Fertility and Sterility - FERT STERIL. 01/2006; 86(3).
  • Fertility and Sterility - FERT STERIL. 01/2005; 84.
  • Fertility and Sterility - FERT STERIL. 01/2005; 84.
  • Fertility and Sterility - FERT STERIL. 01/2005; 84.
  • Fertility and Sterility - FERT STERIL. 01/2005; 84.
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    ABSTRACT: The methanol, hexane and diethyl ether extracts from both leaves and roots of Withania somnifera were evaluated for the antibacterial/synergistic activity by agar plate disc-diffusion assay against Salmonella typhimurium and Escherichia coli. Different concentrations of Tibrim, a combination of rifampicin and isoniazid, were tested to find out the minimum inhibitory concentration (MIC), which came out to be 0.1 mg/ml for S. typhimurium and E. coli. From the six extracts tested, only methanol and hexane extracts of both leaves and roots were found to have potent antibacterial activity. A synergistic increase in the antibacterial effect of Tibrim was noticed when MIC of Tibrim was supplemented with these extracts.
    Fitoterapia 07/2004; 75(3-4):385-8. · 2.23 Impact Factor
  • K Kaur, S Arora, S Kumar, A Nagpal
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    ABSTRACT: The antimutagenic effect of benzene, chloroform, acetone and methanol fractions from Terminalia arjuna, a well-known medicinal plant, was determined against Acid Black dye, 2-aminofluorene (2AF) and 4-nitro-o-phenylenediamine (NPD) in TA98 Frameshift mutagen tester strain of Salmonella typhimurium. Among the different fractions, the antimutagenic effect of acetone and methanol fractions was more than that observed with other fractions. Co-incubation and pre-incubation modes of experimentation did not show much difference in the antimutagenic activity of the extracts. Moreover, these fractions inhibited the S9-dependent mutagens, 2AF and Acid Black dye more effectively than the direct-acting mutagens. Studies are under way to isolate and elucidate the nature of the antimutagenic factor in acetone and methanol fractions.
    Food and Chemical Toxicology 11/2002; 40(10):1475-82. · 3.01 Impact Factor
  • S Kaur, S Arora, K Kaur, S Kumar
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    ABSTRACT: A study to evaluate an antimutagenic potential of water, chloroform and acetone extracts of Triphala has been made in an Ames histidine reversion assay using TA98 and TA100 tester strains of Salmonella typhimurium against the direct-acting mutagens, 4-nitro-o-phenylenediamine (NPD) and sodium azide, and the indirect-acting promutagen, 2-aminofluorene (2AF), in the presence of phenobarbitone-induced rat hepatic S9. A combination drug 'Triphala' - a composite mixture of Terminalia bellerica, T. chebula and Emblica officinalis, has been used in traditional system of medicine for the treatment of many malaises, such as heart ailments and hepatic diseases. The drug was sequentially extracted with water, acetone and chloroform at room temperature. The study revealed that water extract was ineffective in reducing the revertants induced by the mutagens. The results with chloroform and acetone extracts showed inhibition of mutagenicity induced by both direct and S9-dependent mutagens. A significant inhibition of 98.7% was observed with acetone extract against the revertants induced by S9-dependent mutagen, 2AF, in co-incubation mode of treatment. Various spectroscopic techniques, namely 1H-NMR, normal 13C-NMR, distortionless enhancement by polarization transfer (DEPT-90 and DEPT-135), UV and IR, are under way to identify the polyphenolic compounds from an acetone extract.
    Food and Chemical Toxicology 05/2002; 40(4):527-34. · 3.01 Impact Factor
  • Reproductive biomedicine online 13:18. · 2.68 Impact Factor
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    ABSTRACT: The aim of this work is to compare the antioxidant efficacy and the phenolic content of two hexane extracts viz. 'Hex 1' and 'Hex 2' of fruits of Terminalia chebula prepared by maceration and sequential method respectively. The extracts were tested for their relative levels of antioxidant activity and the total phenolic content using DPPH, deoxyribose, reducing power, chelating power, lipid peroxidation and Folin-Ciocalteu method. Furthermore, the UV–VIS spectrum of extracts and the correlation between total phenolic content were examined in order to give an orientation to the search of phytochemicals responsible for their activity. From the results, it was concluded that phenolic compounds were predominant in the 'Hex 2' prepared by sequential extraction method. The antioxidative potential of 'Hex 2' was also far superior to the 'Hex 1' prepared by maceration method. Such study would contribute to further knowledge relating to the extraction of plant materials by different methods.
  • Reproductive biomedicine online 17:S-23. · 2.68 Impact Factor