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ABSTRACT: Endotracheal metastases (ETM) from non-lung cancer are seldom seen. Their main clinical symptoms are cough, haemoptysis and dyspnoea, although occasionally an incidental finding is made during a bronchoscopy. Breast, colon and kidney adenocarcinoma might be associated with ETM, lung cancer being the most frequent cause. Its finding is associated with advanced disease but survival will depend on the primary origin, patient status and comorbidity. Therefore, treatment should be individual for each patient. In our centre we recommend pre-surgery bronchoscopy to exclude metastatic endotracheal lesions in patients with metastatic colon adenocarcinoma disease, as this might affect the final outcome and therefore management of the disease.
Clinical and Translational Oncology 11/2008; 10(10):676-8. · 1.33 Impact Factor
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ABSTRACT: Solitary fibrous tumors of the pleura are uncommon and mainly arise in the pleura itself. Such tumors are generally asymptomatic and slow-growing. We report a series of 10 cases (8 men and 2 women with a mean age of 58.6 years) treated over a period of 54 months. The tumors were classified histologically as benign or malignant according to the criteria used by England. The treatment of choice was complete resection of the tumor. Six posterolateral thoracotomies and 4 video-assisted resections were performed. Histology showed a mixture of fibroblast-like cells and collagenous stroma. Sarcomatous degeneration was observed in the excised tumor of 1 patient. The patients were followed for a mean of 23.9 months. We conclude that although fibrous tumors of the pleura are considered benign histologically, complete resection and follow up for all patients are recommended.
Archivos de Bronconeumología 10/2004; 40(9):419-21. · 2.17 Impact Factor
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ABSTRACT: Protocols for treating acute asthma presently rely on measurement of peak expiratory flow (PEF) to orient treatment and evaluate progress. Other clinical or functional parameters have also been considered for use in the assessment of severity of attack. In order to investigate the usefulness of these criteria we analyzed their relation to degree of air flow obstruction expressed by PEF in a sample of 48 asthmatics who came to the emergency room for treatment of disease exacerbation, excluding 6 who presented imminent risk of death at the time of admission. Among the clinical parameters analyzed, only presentation of cyanosis or diaphoresis was related to degree of obstruction. The pattern of accessory muscle use or vital signs such as heart, breathing rate or blood pressure were similar in patients with (PEF < 50%) or without (PEF > 50%) severe exacerbation. Among gasometric readings only PaO2 was significantly lower in patients with PEF < 50% and we were able to identify a cutoff point useful as a screen for respiratory insufficiency: when the initial PEF was above 50% of theoretical value, no patient had PaO2 < 60 mmHg. We conclude that: 1) clinical parameters do not always reflect severity of attack established by degree of air flow obstruction, and 2) PEF > 50% at the start of asthmatic exacerbation allows respiratory insufficiency to be ruled out, making performance of gasometric measurement unnecessary.
Archivos de Bronconeumología 01/1996; 32(1):4-9. · 2.17 Impact Factor
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ABSTRACT: We describe 9 patients with coincident active tuberculosis of the lung and bronchogenic carcinoma who were all diagnosed within a 5-year period. All were men, with a mean age of 55 +/- 10 years. The principal symptom was toxic syndrome lasting 1-3 months and the most common X-ray sign was alveolar consolidation. Analysis of tissue samples revealed squamous carcinoma (4 cases), adenocarcinoma (4 cases, one of which was bronchioloalveolar) and non-small cell carcinoma (1 case). Tumoral stage was often advanced: IV (44%) and III (33%). The tuberculosis bacillus was isolated in sputum (100%) and in bronchial aspirate (50%); no in vitro resistance was observed. Three patients were treated with radical surgery and three with radiotherapy. Average survival was 3 months in this series.
Archivos de Bronconeumología 02/1995; 31(1):32-4. · 2.17 Impact Factor
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ABSTRACT: Los tumores fibrosos pleurales solitarios son lesiones infrecuentes que en su mayoría derivan de la pleura. Generalmente asintomáticos, poseen un crecimiento lento. En el presente trabajo se describe una serie de 10 casos (8 varones y 2 mujeres, con una edad media de 58,6 años) tratados en un período de 54 meses. Histológicamente se clasificaron como benignos o malignos basándose en los criterios de England. El tratamiento de elección fue la cirugía con criterios de resección completa. Se realizaron 6 toracotomías posterolaterales y 4 resecciones por videocirugía. Microscópicamente estaban constituidos por células de aspecto fibroblástico, entremezcladas con estroma colagenizada. Uno de los pacientes presentó una degeneración sarcomatosa en la pieza. Se siguió a los pacientes en consultas, con un seguimiento medio de 23,9 meses. En conclusión, los tumores fibrosos pleurales, aunque considerados histológicamente benignos, precisan de la resección completa. Se recomienda el seguimiento evolutivo en todos los pacientes
Archivos de bronconeumología: Organo oficial de la Sociedad Española de Neumología y Cirugía Torácica SEPAR y la Asociación Latinoamericana de Tórax (ALAT), ISSN 0300-2896, Vol. 40, Nº. 9, 2004, pags. 419-421.
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ABSTRACT: Solitary fibrous tumors of the pleura are uncommon and mainly arise in the pleura itself. Such tumors are generally asymptomatic and slow-growing. We report a series of 10 cases (8 men and 2 women with a mean age of 58.6 years) treated over a period of 54 months. The tumors were classified histologically as benign or malignant according to the criteria used by England. The treatment of choice was complete resection of the tumor.Six posterolateral thoracotomies and 4 video-assisted resections were performed. Histology showed a mixture of fibroblast-like cells and collagenous stroma. Sarcomatous degeneration was observed in the excised tumor of 1 patient. The patients were followed for a mean of 23.9 months.We conclude that although fibrous tumors of the pleura are considered benign histologically, complete resection and follow up for all patients are recommended.Los tumores fibrosos pleurales solitarios son lesiones in-frecuentes que en su mayoría derivan de la pleura. Generalmente asintomáticos, poseen un crecimiento lento. En el presente trabajo se describe una serie de 10 casos (8 varones y 2 mujeres, con una edad media de 58,6 años) tratados en un período de 54 meses. Histológicamente se clasifi-caron como benignos o malignos basándose en los criterios de England. El tratamiento de elección fue la cirugía con criterios de resección completa.Se realizaron 6 toracotomías posterolaterales y 4 resecciones por videocirugía. Microscópicamente estaban constituidos por células de aspecto fibroblástico, entremezcladas con estroma colagenizada. Uno de los pacientes presentó una degeneración sarcomatosa en la pieza. Se siguió a los pacientes en consultas, con un seguimiento medio de 23,9 meses.En conclusión, los tumores fibrosos pleurales, aunque considerados histológicamente benignos, precisan de la resección completa. Se recomienda el seguimiento evolutivo en todos los pacientes.
Archivos de Bronconeumología ((English Edition)).
